DK4011887T3 - Sammensætninger og fremgangsmåder til hæmning af arginaseaktivitet - Google Patents

Sammensætninger og fremgangsmåder til hæmning af arginaseaktivitet Download PDF

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Publication number
DK4011887T3
DK4011887T3 DK22150809.6T DK22150809T DK4011887T3 DK 4011887 T3 DK4011887 T3 DK 4011887T3 DK 22150809 T DK22150809 T DK 22150809T DK 4011887 T3 DK4011887 T3 DK 4011887T3
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Denmark
Prior art keywords
compositions
methods
arginase activity
inhibiting arginase
inhibiting
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DK22150809.6T
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English (en)
Inventor
Eric B Sjogren
Jim Li
Zandt Michael Van
Darren Whitehouse
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Prec Pharmaceuticals Inc
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Publication of DK4011887T3 publication Critical patent/DK4011887T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
DK22150809.6T 2015-10-30 2016-10-28 Sammensætninger og fremgangsmåder til hæmning af arginaseaktivitet DK4011887T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562248632P 2015-10-30 2015-10-30
US201662281964P 2016-01-22 2016-01-22
US201662323034P 2016-04-15 2016-04-15
EP20165627.9A EP3693375B1 (en) 2015-10-30 2016-10-28 Compositions and methods for inhibiting arginase activity

Publications (1)

Publication Number Publication Date
DK4011887T3 true DK4011887T3 (da) 2024-10-28

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK16860883.4T DK3368541T3 (da) 2015-10-30 2016-10-28 Sammensætninger og metoder til inhibiering af arginaseaktivitet
DK22150809.6T DK4011887T3 (da) 2015-10-30 2016-10-28 Sammensætninger og fremgangsmåder til hæmning af arginaseaktivitet

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK16860883.4T DK3368541T3 (da) 2015-10-30 2016-10-28 Sammensætninger og metoder til inhibiering af arginaseaktivitet

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US (4) US10065974B2 (da)
EP (3) EP3693375B1 (da)
JP (3) JP6833844B2 (da)
KR (2) KR20220118559A (da)
CN (4) CN113201002A (da)
AU (3) AU2016343656B2 (da)
BR (3) BR122020022280B1 (da)
CA (1) CA3003271A1 (da)
CL (4) CL2018001134A1 (da)
CO (1) CO2018004750A2 (da)
CR (3) CR20210389A (da)
CY (1) CY1123557T1 (da)
DK (2) DK3368541T3 (da)
EA (1) EA038276B1 (da)
EC (1) ECSP18040250A (da)
ES (3) ES2910928T3 (da)
HR (1) HRP20201046T1 (da)
HU (1) HUE054972T2 (da)
IL (3) IL258731B (da)
LT (1) LT3368541T (da)
MA (2) MA50636A (da)
MD (1) MD3368541T2 (da)
MX (1) MX2018005294A (da)
MY (1) MY201783A (da)
NZ (1) NZ742742A (da)
PH (2) PH12022551082A1 (da)
PL (1) PL3368541T3 (da)
PT (1) PT3368541T (da)
RS (1) RS60695B1 (da)
SG (4) SG10201911402YA (da)
SI (1) SI3368541T1 (da)
SM (1) SMT202000469T1 (da)
TW (3) TWI710565B (da)
UA (1) UA125289C2 (da)
WO (1) WO2017075363A1 (da)
ZA (4) ZA201803556B (da)

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ZA201907091B (en) 2021-05-26
SMT202000469T1 (it) 2020-11-10
CR20210390A (es) 2021-10-19
UA125289C2 (uk) 2022-02-16
US10844080B2 (en) 2020-11-24
MA43131B1 (fr) 2020-07-29
PH12022551082A1 (en) 2023-03-13
RS60695B1 (sr) 2020-09-30
IL288225A (en) 2022-01-01
EP3368541A1 (en) 2018-09-05
BR122020022280B1 (pt) 2022-05-03
DK3368541T3 (da) 2020-06-29
EP4011887A1 (en) 2022-06-15
BR122020022275B1 (pt) 2022-05-03
JP7032583B2 (ja) 2022-03-08
CA3003271A1 (en) 2017-05-04
TWI775556B (zh) 2022-08-21
US20210061822A1 (en) 2021-03-04
MX2018005294A (es) 2018-09-21
TW201726692A (zh) 2017-08-01
US10065974B2 (en) 2018-09-04
AU2016343656B2 (en) 2020-09-17
MY201783A (en) 2024-03-18
IL281503B (en) 2022-01-01
EP3368541A4 (en) 2019-07-17
ES2910928T3 (es) 2022-05-17
CL2019000819A1 (es) 2019-08-09
TW202110858A (zh) 2021-03-16
KR102434308B1 (ko) 2022-08-19
ECSP18040250A (es) 2018-10-31
MA50636A (fr) 2021-04-14
EA201891057A1 (ru) 2018-12-28
JP6833844B2 (ja) 2021-02-24
JP2021075543A (ja) 2021-05-20
CO2018004750A2 (es) 2018-10-31
TW202146028A (zh) 2021-12-16
EA038276B1 (ru) 2021-08-04
EP3693375A1 (en) 2020-08-12
KR20220118559A (ko) 2022-08-25
AU2016343656A1 (en) 2018-06-07
ES2808988T3 (es) 2021-03-02
CN113150016A (zh) 2021-07-23
HK1252560A1 (en) 2019-05-31
MD3368541T2 (ro) 2020-09-30
IL258731B (en) 2021-04-29
US10851118B2 (en) 2020-12-01
PH12018500899A1 (en) 2018-10-29
CR20180282A (es) 2018-11-30
JP2022071010A (ja) 2022-05-13
SG10201911402YA (en) 2020-02-27
AU2020286278A1 (en) 2021-01-14
TWI734630B (zh) 2021-07-21
EP3693375B1 (en) 2022-02-16
AU2020286278B2 (en) 2022-03-17
AU2022203703A1 (en) 2022-06-16
US20170121352A1 (en) 2017-05-04
CL2018001134A1 (es) 2018-10-26
SG11201802961PA (en) 2018-05-30
CN113150015A (zh) 2021-07-23
SG10201911406TA (en) 2020-01-30
CN108271371A (zh) 2018-07-10
LT3368541T (lt) 2020-09-25
HRP20201046T1 (hr) 2020-10-16
CN108271371B (zh) 2021-02-09
KR20180084063A (ko) 2018-07-24
ZA201907092B (en) 2021-04-28
PH12018500899B1 (en) 2023-02-08
SI3368541T1 (sl) 2020-10-30
BR112018008746A2 (pt) 2018-10-30
CN113201002A (zh) 2021-08-03
PT3368541T (pt) 2020-07-06
CR20210389A (es) 2021-09-16
WO2017075363A1 (en) 2017-05-04
EP3368541B1 (en) 2020-05-27
ES2991555T3 (es) 2024-12-04
ZA201803556B (en) 2021-02-24
EP4011887B1 (en) 2024-07-31
HUE054972T2 (hu) 2021-10-28
ZA201907093B (en) 2021-03-31
CL2019000821A1 (es) 2019-08-09
NZ742742A (en) 2023-04-28
SG10202003966RA (en) 2020-06-29
CL2019000820A1 (es) 2019-08-09
CY1123557T1 (el) 2022-03-24
BR112018008746B1 (pt) 2021-11-16
PL3368541T3 (pl) 2020-11-02
IL258731A (en) 2018-06-28
TWI710565B (zh) 2020-11-21
IL281503A (en) 2021-04-29
JP2018533582A (ja) 2018-11-15
US20180346489A1 (en) 2018-12-06
BR112018008746A8 (pt) 2019-02-26
US20200223872A1 (en) 2020-07-16

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