DK416289A - Estere af 3-demethylthiocolchicin og n-acylanaloger - Google Patents

Estere af 3-demethylthiocolchicin og n-acylanaloger

Info

Publication number
DK416289A
DK416289A DK416289A DK416289A DK416289A DK 416289 A DK416289 A DK 416289A DK 416289 A DK416289 A DK 416289A DK 416289 A DK416289 A DK 416289A DK 416289 A DK416289 A DK 416289A
Authority
DK
Denmark
Prior art keywords
demethylthiocolchicine
esters
acyl analogs
alkyl
analogs
Prior art date
Application number
DK416289A
Other languages
Danish (da)
English (en)
Other versions
DK416289D0 (da
Inventor
Arnold Brossi
Original Assignee
Advance Biofactures Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advance Biofactures Corp filed Critical Advance Biofactures Corp
Publication of DK416289D0 publication Critical patent/DK416289D0/da
Publication of DK416289A publication Critical patent/DK416289A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40Y being a hydrogen or a carbon atom
    • C07C323/41Y being a hydrogen or an acyclic carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK416289A 1988-08-24 1989-08-23 Estere af 3-demethylthiocolchicin og n-acylanaloger DK416289A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23590788A 1988-08-24 1988-08-24

Publications (2)

Publication Number Publication Date
DK416289D0 DK416289D0 (da) 1989-08-23
DK416289A true DK416289A (da) 1990-02-25

Family

ID=22887351

Family Applications (1)

Application Number Title Priority Date Filing Date
DK416289A DK416289A (da) 1988-08-24 1989-08-23 Estere af 3-demethylthiocolchicin og n-acylanaloger

Country Status (10)

Country Link
EP (1) EP0356137B1 (fr)
JP (1) JPH02142765A (fr)
AT (1) ATE113273T1 (fr)
AU (1) AU618395B2 (fr)
CA (1) CA1338432C (fr)
DE (1) DE68919025T2 (fr)
DK (1) DK416289A (fr)
ES (1) ES2062014T3 (fr)
FI (1) FI95461C (fr)
ZA (1) ZA896411B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1270124B (it) * 1994-10-05 1997-04-28 Indena Spa Derivati della colchicina e loro impiego terapeutico
IT1291550B1 (it) * 1997-04-11 1999-01-11 Indena Spa Derivati della colchicina e della tiocolchicina ad attivita' antinfiammatoria e miorilassante
US8497290B2 (en) 2009-05-27 2013-07-30 Takeda Pharmaceuticals U.S.A., Inc. Thiocolchicine derivatives, method of making and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US235907A (en) * 1880-12-28 sqhlimp
FR1099138A (fr) * 1954-02-10 1955-08-30 Roussel Uclaf Thiodérivés tropoloniques de la colchicine et leur procédé d'obtention
US2820029A (en) * 1954-02-10 1958-01-14 U C L A F New thio-derivatives of colchiceine compounds and a process of making same

Also Published As

Publication number Publication date
ES2062014T3 (es) 1994-12-16
AU4019189A (en) 1990-03-01
EP0356137A3 (en) 1990-11-07
EP0356137B1 (fr) 1994-10-26
FI95461C (fi) 1996-02-12
FI893955L (fi) 1990-02-25
FI95461B (fi) 1995-10-31
AU618395B2 (en) 1991-12-19
DE68919025T2 (de) 1995-03-02
DE68919025D1 (de) 1994-12-01
DK416289D0 (da) 1989-08-23
ZA896411B (en) 1990-05-30
ATE113273T1 (de) 1994-11-15
CA1338432C (fr) 1996-07-02
JPH02142765A (ja) 1990-05-31
FI893955A0 (fi) 1989-08-23
EP0356137A2 (fr) 1990-02-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment