DK428678A - Fremgangsmaade til fremstilling af 4-amino-2-(piperazin-1-yl eller homopiperazin-1-yl)-quinazoliner - Google Patents

Fremgangsmaade til fremstilling af 4-amino-2-(piperazin-1-yl eller homopiperazin-1-yl)-quinazoliner

Info

Publication number: DK428678A
Authority: DK; Denmark
Prior art keywords: homopiperazin; quinazolines; piperazin; amino; procedure
Prior art date: 1977-11-05

Application number

DK428678A

Other languages

English (en)

Other versions

DK154082B (da

DK154082C (da

Inventor

S F Campbell

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-11-05

Filing date

1978-09-27

Publication date

1979-05-06

1978-09-27 Application filed by Pfizer filed Critical Pfizer

1978-10-18 Priority to US05/952,317 priority Critical patent/US4188390A/en

1979-05-06 Publication of DK428678A publication Critical patent/DK428678A/da

1988-10-10 Publication of DK154082B publication Critical patent/DK154082B/da

1989-02-27 Application granted granted Critical

1989-02-27 Publication of DK154082C publication Critical patent/DK154082C/da

1992-03-16 Priority to BG096072A priority patent/BG60337B2/bg

Links

-1 PIPERAZIN-1-YL Chemical class 0.000 title 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK428678A 1977-11-05 1978-09-27 Analogifremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(piperazin-1-yl eller homopiperazin-1-yl)-quinazolinforbindelser eller farmaceutisk acceptable syreadditionssalte deraf DK154082C (da)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
US05/952,317 US4188390A (en)	1977-11-05	1978-10-18	Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
BG096072A BG60337B2 (bg)	1977-11-05	1992-03-16	4-амино-2-(4-)1,4-бензодиоксан-2-карбонил(пиперазин-1-ил или хомопиперазин-1-ил)хиназолини с антихипертензивно действие

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB4612877		1977-11-05
GB4612877		1977-11-05

Publications (3)

Publication Number	Publication Date
DK428678A true DK428678A (da)	1979-05-06
DK154082B DK154082B (da)	1988-10-10
DK154082C DK154082C (da)	1989-02-27

Family

ID=10439957

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK428678A DK154082C (da)	1977-11-05	1978-09-27	Analogifremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(piperazin-1-yl eller homopiperazin-1-yl)-quinazolinforbindelser eller farmaceutisk acceptable syreadditionssalte deraf

Country Status (36)

Country	Link
JP (1)	JPS5498792A (da)
AR (2)	AR219562A1 (da)
AT (1)	AT365186B (da)
AU (1)	AU509329B2 (da)
BE (1)	BE871771A (da)
CA (1)	CA1088059A (da)
CH (1)	CH643255A5 (da)
CS (2)	CS207671B2 (da)
DD (1)	DD139850A5 (da)
DE (1)	DE2847623C2 (da)
DK (1)	DK154082C (da)
EG (1)	EG13594A (da)
ES (2)	ES474805A1 (da)
FI (1)	FI64366C (da)
FR (1)	FR2407929A1 (da)
GR (1)	GR81514B (da)
HK (1)	HK94284A (da)
HU (1)	HU176306B (da)
IE (1)	IE47888B1 (da)
IL (1)	IL55857A (da)
IN (1)	IN148828B (da)
IT (1)	IT1100919B (da)
KE (1)	KE3350A (da)
LU (2)	LU80470A1 (da)
MY (1)	MY8500286A (da)
NL (2)	NL174549C (da)
NO (1)	NO150158C (da)
NZ (1)	NZ188813A (da)
PH (1)	PH13966A (da)
PL (2)	PL119586B1 (da)
PT (1)	PT68735A (da)
SE (1)	SE437518B (da)
SU (1)	SU816403A3 (da)
UA (1)	UA8324A1 (da)
YU (2)	YU40204B (da)
ZA (1)	ZA786184B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1986002644A1 (fr) *	1984-11-01	1986-05-09	Takeda Chemical Industries, Ltd.	Derives de 1,5-benzoxathiepines et leur procede de preparation
WO1985004658A1 (fr) *	1984-04-04	1985-10-24	Takeda Chemical Industries, Ltd.	Derives de 1,5 benzoxathiepine et leur preparation
WO1985002617A1 (fr) *	1983-12-14	1985-06-20	Takeda Chemical Industries. Ltd.	Derives de 1,5-benzoxathiepine et leur procede de preparation
EP0849265A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von Doxazosin-Mesylat (Form II)
DE59611417D1 (de) *	1996-12-20	2007-03-29	Heumann Pharma Gmbh & Co	Neue polymorphe Form von Doxazosinmesylat (Form III)
EP0849264A1 (de) *	1996-12-20	1998-06-24	HEUMANN PHARMA GmbH	Neue polymorphe Form von doxazosinmesylat (Form I)
TW448155B (en) *	1999-03-29	2001-08-01	Dev Center Biotechnology	Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (en) *	2002-09-27	2005-06-22	Council of Scientific and Industrial Research	Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3635979A (en) *	1969-09-29	1972-01-18	Pfizer	Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
US3669968A (en) *	1970-05-21	1972-06-13	Pfizer	Trialkoxy quinazolines

1978
- 1978-09-27 DK DK428678A patent/DK154082C/da active
- 1978-10-03 IN IN712/DEL/78A patent/IN148828B/en unknown
- 1978-10-24 CA CA314,027A patent/CA1088059A/en not_active Expired
- 1978-10-24 PH PH21726A patent/PH13966A/en unknown
- 1978-10-31 UA UA2679598A patent/UA8324A1/uk unknown
- 1978-10-31 SU SU782679598A patent/SU816403A3/ru active
- 1978-11-02 DE DE2847623A patent/DE2847623C2/de not_active Expired
- 1978-11-02 NL NLAANVRAGE7810909,A patent/NL174549C/xx not_active IP Right Cessation
- 1978-11-02 CH CH1132178A patent/CH643255A5/de not_active IP Right Cessation
- 1978-11-02 JP JP13569578A patent/JPS5498792A/ja active Granted
- 1978-11-02 CS CS787166A patent/CS207671B2/cs unknown
- 1978-11-02 GR GR57562A patent/GR81514B/el unknown
- 1978-11-02 SE SE7811382A patent/SE437518B/sv not_active IP Right Cessation
- 1978-11-02 IL IL55857A patent/IL55857A/xx unknown
- 1978-11-02 NZ NZ188813A patent/NZ188813A/xx unknown
- 1978-11-02 AT AT0784378A patent/AT365186B/de not_active IP Right Cessation
- 1978-11-02 YU YU2553/78A patent/YU40204B/xx unknown
- 1978-11-02 PT PT68735A patent/PT68735A/pt unknown
- 1978-11-02 HU HU78PI648A patent/HU176306B/hu unknown
- 1978-11-02 AR AR274321A patent/AR219562A1/es active
- 1978-11-02 FI FI783347A patent/FI64366C/fi not_active IP Right Cessation
- 1978-11-02 ZA ZA00786184A patent/ZA786184B/xx unknown
- 1978-11-03 LU LU80470A patent/LU80470A1/fr unknown
- 1978-11-03 AU AU41322/78A patent/AU509329B2/en not_active Expired
- 1978-11-03 ES ES474805A patent/ES474805A1/es not_active Expired
- 1978-11-03 FR FR7831126A patent/FR2407929A1/fr active Granted
- 1978-11-03 PL PL1978210681A patent/PL119586B1/pl unknown
- 1978-11-03 BE BE191544A patent/BE871771A/xx not_active IP Right Cessation
- 1978-11-03 NO NO783705A patent/NO150158C/no unknown
- 1978-11-03 PL PL1978216980A patent/PL119419B1/pl unknown
- 1978-11-03 IT IT29434/78A patent/IT1100919B/it active Protection Beyond IP Right Term
- 1978-11-03 DD DD78208868A patent/DD139850A5/de unknown
- 1978-11-03 IE IE2179/78A patent/IE47888B1/en active Protection Beyond IP Right Term
- 1978-11-04 EG EG641/78A patent/EG13594A/xx active
1979
- 1979-04-30 ES ES480121A patent/ES480121A0/es active Granted
- 1979-10-18 AR AR278545A patent/AR223015A1/es active
1983
- 1983-02-17 YU YU386/83A patent/YU40419B/xx unknown
- 1983-11-21 KE KE3350A patent/KE3350A/xx unknown
1984
- 1984-11-29 HK HK942/84A patent/HK94284A/xx not_active IP Right Cessation
1985
- 1985-12-30 MY MY286/85A patent/MY8500286A/xx unknown
1991
- 1991-11-22 CS CS913544A patent/CS354491A3/cs unknown
1993
- 1993-06-11 NL NL930062C patent/NL930062I2/nl unknown
- 1993-06-24 LU LU88331C patent/LU88331I2/fr unknown

Also Published As

Publication number	Publication date
ES8308559A1 (es)	1980-07-16
IE47888B1 (en)	1984-07-11
SU816403A3 (ru)	1981-03-23
UA8324A1 (uk)	1996-03-29
AU509329B2 (en)	1980-05-08
CS207671B2 (en)	1981-08-31
DK154082B (da)	1988-10-10
PH13966A (en)	1980-11-12
SE437518B (sv)	1985-03-04
ATA784378A (de)	1981-05-15
IL55857A (en)	1982-07-30
FR2407929B1 (da)	1981-02-27
AR223015A1 (es)	1981-07-15
NO150158C (no)	1984-08-29
FI64366B (fi)	1983-07-29
IE782179L (en)	1979-05-05
YU40204B (en)	1985-08-31
NO150158B (no)	1984-05-21
BE871771A (fr)	1979-05-03
IN148828B (da)	1981-06-27
FI64366C (fi)	1983-11-10
DK154082C (da)	1989-02-27
NZ188813A (en)	1980-10-08
PL210681A1 (da)	1979-11-05
MY8500286A (en)	1985-12-31
YU40419B (en)	1985-12-31
ES480121A0 (es)	1980-07-16
NO783705L (no)	1979-05-08
LU80470A1 (fr)	1980-06-05
JPS5498792A (en)	1979-08-03
ES474805A1 (es)	1980-01-16
AR219562A1 (es)	1980-08-29
DE2847623C2 (de)	1983-06-01
PT68735A (en)	1978-12-01
NL7810909A (nl)	1979-05-08
PL119586B1 (en)	1982-01-30
CH643255A5 (en)	1984-05-30
HK94284A (en)	1984-12-07
FR2407929A1 (fr)	1979-06-01
KE3350A (en)	1983-12-16
CS354491A3 (en)	1992-06-17
YU255378A (en)	1983-06-30
NL174549B (nl)	1984-02-01
IT1100919B (it)	1985-09-28
HU176306B (en)	1981-01-28
LU88331I2 (fr)	1994-05-04
AT365186B (de)	1981-12-28
DE2847623A1 (de)	1979-05-23
EG13594A (en)	1982-03-31
AU4132278A (en)	1979-05-17
ZA786184B (en)	1979-10-31
IL55857A0 (en)	1979-01-31
FI783347A7 (fi)	1979-05-06
NL930062I2 (nl)	1993-11-16
PL119419B1 (en)	1981-12-31
DD139850A5 (de)	1980-01-23
YU38683A (en)	1983-06-30
NL174549C (nl)	1984-07-02
IT7829434A0 (it)	1978-11-03
CA1088059A (en)	1980-10-21
NL930062I1 (nl)	1993-09-01
GR81514B (da)	1984-12-11
JPS5625233B2 (da)	1981-06-11
SE7811382L (sv)	1979-05-06

Publication	Publication Date	Title
DK110778A (da)	1978-09-15	Fremgangsmaade til fremstilling af 4-acylamino-phenyl-ethanolaminer
DK306978A (da)	1979-01-12	Fremgangsmaade til fremstilling af 1-acyl-2-cyanaziridiner
DK569678A (da)	1979-06-21	Fremgangsmaade til fremstilling af 2alfa-cyano-3-oxosteroider
DK484677A (da)	1979-04-04	Fremgangsmaade til fremstilling af furokumariner
DK145701C (da)	1983-07-18	Fremgangsmaade til fremstilling af ergotalkaloider
DK172578A (da)	1978-10-23	Fremgangsmaade til fremstilling af anilinderivater
DK146578A (da)	1978-10-05	Fremgangsmaade til fremstilling af interphenylen 8-aza-9-dioxothia-11%12-secoprostaglandiner
DK466878A (da)	1979-04-21	Fremgangsmaade til fremstilling af 0-methallyloxyphenol
DK393778A (da)	1979-03-22	Fremgangsmaade til fremstilling af serinol
DK237978A (da)	1979-01-19	Fremgangsmaade til fremstilling af alfafluormethyl-alfa-aminoalkansyrer
DK154949C (da)	1989-05-29	Fremgangsmaade til fremstilling af trifluormethylphenoler
DK436978A (da)	1979-04-05	Fremgangsmaade til fremstilling af sarcosinoxidase
DK577078A (da)	1979-06-28	Fremgangsmaade til fremstilling af trans-4a-aryloctahydro-1h-2-pyridiner
DK5778A (da)	1978-07-12	Femgangsmaade til fremstilling af 4-diphenylmethylen-1-hydroxybenzyl-piperidiner
DK71378A (da)	1978-08-20	Fremgangsmaade til fremstilling af halogenmethylerede diphenylethere
DK248978A (da)	1978-12-05	Fremgangsmaade til fremstilling af hydroxy-alfa-aminobenzylpenicillin
DK261278A (da)	1979-12-15	Fremgangsmaade til fremstilling af 24-dehydrovitamin d-3-derivater
DK353478A (da)	1979-02-12	Fremgangsmaade til fremstilling af urethangruppeholdige skumstoffer
DK246878A (da)	1978-12-04	Fremgangsmaade til fremstilling af acylderivater
DK262178A (da)	1978-12-14	Fremgangsmaade til fremstilling af 2-keto-l-gulonsyre eller estere eller d-enantiomere heraf
DK154778A (da)	1978-10-10	Fremgangsmaade til fremstilling af phosphorylerede amidiner
DK339777A (da)	1978-10-30	Fremgangsmaade til fremstilling af 2-benzylperhydroazepiner
DK275378A (da)	1978-12-29	Fremgangsmaade til fremstilling af indanderivater
DK158976C (da)	1990-12-31	Fremgangsmaade til fremstilling af alfa-cyanobenzyl
DK206178A (da)	1978-11-12	Fremgangsmaade til fremstilling af 3-bromphthalid