DK456389A - Broforbundne bicycliske imider med en 4-oe4-(3-benzisothiazolyl)-1-piperazinylaabutylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske praeparater indeholdende disse - Google Patents

Broforbundne bicycliske imider med en 4-oe4-(3-benzisothiazolyl)-1-piperazinylaabutylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske praeparater indeholdende disse Download PDF

Info

Publication number
DK456389A
DK456389A DK456389A DK456389A DK456389A DK 456389 A DK456389 A DK 456389A DK 456389 A DK456389 A DK 456389A DK 456389 A DK456389 A DK 456389A DK 456389 A DK456389 A DK 456389A
Authority
DK
Denmark
Prior art keywords
benzisothiazolyl
piperazinylaabutyl
imidnitrogen
antipsycotic
atoms
Prior art date
Application number
DK456389A
Other languages
English (en)
Other versions
DK175200B1 (da
DK456389D0 (da
Inventor
Gene Michael Bright
Iii John Adams Lowe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK456389D0 publication Critical patent/DK456389D0/da
Publication of DK456389A publication Critical patent/DK456389A/da
Application granted granted Critical
Publication of DK175200B1 publication Critical patent/DK175200B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK198904563A 1988-09-16 1989-09-15 Broforbundne bicycliske imider med en 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske præparater indeholdende disse DK175200B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1988/003230 WO1990002552A1 (en) 1988-09-16 1988-09-16 Antipsychotic 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butyl bridged bicyclic imides
US8803230 1988-09-16

Publications (3)

Publication Number Publication Date
DK456389D0 DK456389D0 (da) 1989-09-15
DK456389A true DK456389A (da) 1990-03-17
DK175200B1 DK175200B1 (da) 2004-07-05

Family

ID=22208913

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198904563A DK175200B1 (da) 1988-09-16 1989-09-15 Broforbundne bicycliske imider med en 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske præparater indeholdende disse

Country Status (20)

Country Link
US (1) US5077295A (da)
EP (1) EP0364091B1 (da)
JP (1) JPH0631231B2 (da)
KR (1) KR930002568B1 (da)
AT (1) ATE92063T1 (da)
AU (1) AU607354B2 (da)
CA (1) CA1339314C (da)
DE (1) DE68907845T2 (da)
DK (1) DK175200B1 (da)
ES (1) ES2058542T3 (da)
FI (1) FI911285A7 (da)
HU (1) HUT61760A (da)
IE (1) IE61413B1 (da)
IL (1) IL91552A (da)
MY (1) MY104207A (da)
NO (1) NO911042L (da)
NZ (1) NZ230672A (da)
PT (1) PT91703B (da)
WO (1) WO1990002552A1 (da)
ZA (1) ZA897049B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235283A (en) * 1991-02-07 1993-08-10 Siemens Aktiengesellschaft Gradient coil system for a nuclear magnetic resonance tomography apparatus which reduces acoustic noise
ES2210450T3 (es) * 1996-02-13 2004-07-01 Pfizer Inc. Profarmacos de 5-(2-(4-(1,2-benzoisotiazol-3-il)-1-piperazinil)etil)-6-cloro-1,3-dihidro-2h-indol-2-ona.
US6084097A (en) * 1997-10-20 2000-07-04 Council Of Scientific & Industrial Research Methods for preparing 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl] propanes
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
JPS5995267A (ja) * 1982-11-25 1984-06-01 Eisai Co Ltd カルボン酸イミド誘導体およびその製造方法
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4562255A (en) * 1984-03-30 1985-12-31 American Home Products Corporation Substituted bi-alicyclic imides
US4585773A (en) * 1984-07-11 1986-04-29 Bristol-Myers Company Isoindolinyl-alkyl-piperazines
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
JPH0625181B2 (ja) * 1985-03-27 1994-04-06 住友製薬株式会社 新規なイミド誘導体
US4656173A (en) * 1985-04-24 1987-04-07 Bristol-Myers Company Antipsychotic benzisothiazole S-oxide compound
NL8601494A (nl) * 1985-06-22 1987-01-16 Sandoz Ag Thiazolen, hun bereiding en farmaceutische preparaten die ze bevatten.
US4732984A (en) * 1985-10-17 1988-03-22 American Home Products Corporation Piperazinoisothiazolones with psychotropic activity
JPS6310786A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd 新規イミド誘導体およびその製造法
JPS6310760A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd イミド誘導体の新規製造法
DD263531A5 (de) * 1986-10-21 1989-01-04 ������@���Kk�� Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
US4883795A (en) * 1988-01-22 1989-11-28 Pfizer Inc. Piperazinyl-heterocyclic compounds
JPH0310760A (ja) * 1989-06-09 1991-01-18 Nippon Spindle Mfg Co Ltd 結晶質脆性材料切断用ワイヤソー

Also Published As

Publication number Publication date
DK175200B1 (da) 2004-07-05
FI911285A0 (fi) 1991-03-15
MY104207A (en) 1994-02-28
EP0364091B1 (en) 1993-07-28
IL91552A0 (en) 1990-04-29
DK456389D0 (da) 1989-09-15
US5077295A (en) 1991-12-31
PT91703A (pt) 1990-03-30
IE892949L (en) 1990-03-16
ZA897049B (en) 1991-04-24
EP0364091A1 (en) 1990-04-18
ES2058542T3 (es) 1994-11-01
IE61413B1 (en) 1994-11-02
KR900004730A (ko) 1990-04-12
KR930002568B1 (ko) 1993-04-03
HUT61760A (en) 1993-03-01
JPH02121986A (ja) 1990-05-09
AU607354B2 (en) 1991-02-28
NZ230672A (en) 1990-12-21
NO911042L (no) 1991-05-15
FI911285A7 (fi) 1991-03-15
CA1339314C (en) 1997-08-19
DE68907845T2 (de) 1993-11-11
PT91703B (pt) 1995-07-18
WO1990002552A1 (en) 1990-03-22
JPH0631231B2 (ja) 1994-04-27
IL91552A (en) 1994-02-27
ATE92063T1 (de) 1993-08-15
AU4150689A (en) 1990-03-22
NO911042D0 (no) 1991-03-15
DE68907845D1 (de) 1993-09-02

Similar Documents

Publication Publication Date Title
IS1564B (is) Aðferð við framleiðslu á N1-súbstitúeruðum bensimidasólafleiðum til að nota við lækningar
NO166448C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazolidindioner.
HU913283D0 (en) Process for the production of hydroximethyl-(methylene-cyclopentyl)-purines and pirimidines, their medically usable salts, and of medical preparations containing them
MY102016A (en) Thiazolidinedione derivatives, their production and use.
NO163569C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 6-thioxanthinderivater.
BG103219A (bg) Бензамидинови производни и използването им като лекарствени средства с ltb4-антагонистично действие
DK499088A (da) 1-oe(2-pyrimidinyl)-aminoalkylaapiperidinderivater, fremgangsmaade til fremstilling deraf og laegemiddel indeholdende saadanne derivater
ES2017498B3 (es) Derivado de 2-fenilbenzoxepina.
DK53285D0 (da) (-)-trans-4(4-fluorphenyl)-3-(4-methoxyphenoxy)-methylpiperidin, farmaceutisk acceptable syreadditionssalte heraf og farmaceutisk praeparat indeholdende samme
DE3688087D1 (de) Cephemverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
DK456389D0 (da) Broforbundne bicycliske imider med en 4-oe4-(3-benzisothiazolyl)-1-piperazinylaabutylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske praeparater indeholdende disse
NO952900L (no) Materiale inneholdende tandospiron eller analoger derav
DK156474C (da) S-(carbamoylphenylselenyl)-derivater af mercaptaner, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
NO840526L (no) Derivater av n-iminopyridiniumbetainer, fremgangsmaate til deres fremstilling og deres anvendelse i medikamenter
DK248886D0 (da) Spiro-imidazolidin-forbindelser og farmaceutiske praeparater indeholdende disse
NO165393C (no) Fremgansmaate for fremstilling av aryloksypropanolaminer og salter av disse med difenyleddiksyre.
PT85454A (de) Verwendung von 15-deoxyspergualin als arzneimittel
DK614989D0 (da) Indolderivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
NO164170C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzhydryl-4-cinnamyl-piperazinderivater.
DK592988A (da) Laegemiddel, deri indeholdende phosphorholdige 2-isoxazoliner og isoxazoler, samt fremstilling af disse heterocycliske forbindelser
DK400385D0 (da) Arphameninderivater, fremgangsmaade til deres fremstilling samt anvendelse heraf som laegemiddel
NO176177C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-amino-tetrahydroisokinolinderivater

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK