DK46489D0 - Anvendelse af 4-(1-(2,3-dimetylfenyl)-aetyl)-1h-imidazol til fremstilling af laegemidler til perioperativ anvendelse - Google Patents

Anvendelse af 4-(1-(2,3-dimetylfenyl)-aetyl)-1h-imidazol til fremstilling af laegemidler til perioperativ anvendelse

Info

Publication number
DK46489D0
DK46489D0 DK046489A DK46489A DK46489D0 DK 46489 D0 DK46489 D0 DK 46489D0 DK 046489 A DK046489 A DK 046489A DK 46489 A DK46489 A DK 46489A DK 46489 D0 DK46489 D0 DK 46489D0
Authority
DK
Denmark
Prior art keywords
dimethylphenyl
imidazole
ethyl
preparation
medicinal products
Prior art date
Application number
DK046489A
Other languages
English (en)
Other versions
DK46489A (da
DK175282B1 (da
Inventor
Mervyn Maze
Mika Scheinin
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of DK46489D0 publication Critical patent/DK46489D0/da
Publication of DK46489A publication Critical patent/DK46489A/da
Application granted granted Critical
Publication of DK175282B1 publication Critical patent/DK175282B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK198900464A 1988-02-29 1989-02-02 Anvendelse af 4-[1-(2,3-dimetylfenyl)-ætyl]-1H-imidazol til fremstilling af lægemidler til perioperativ anvendelse DK175282B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8804683 1988-02-29
GB8804683A GB2215206B (en) 1988-02-29 1988-02-29 4-substituted imidazole derivatives useful in perioperative care

Publications (3)

Publication Number Publication Date
DK46489D0 true DK46489D0 (da) 1989-02-02
DK46489A DK46489A (da) 1989-08-30
DK175282B1 DK175282B1 (da) 2004-08-09

Family

ID=10632543

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900464A DK175282B1 (da) 1988-02-29 1989-02-02 Anvendelse af 4-[1-(2,3-dimetylfenyl)-ætyl]-1H-imidazol til fremstilling af lægemidler til perioperativ anvendelse

Country Status (13)

Country Link
EP (1) EP0331374B1 (da)
JP (1) JP2856410B2 (da)
KR (1) KR0136790B1 (da)
AT (1) ATE101514T1 (da)
AU (1) AU611262B2 (da)
CA (1) CA1338556C (da)
DE (1) DE68913054T2 (da)
DK (1) DK175282B1 (da)
GB (1) GB2215206B (da)
HU (1) HU202751B (da)
IE (1) IE60538B1 (da)
NZ (1) NZ228125A (da)
ZA (1) ZA891493B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI894911A0 (fi) * 1989-10-17 1989-10-17 Farmos Oy En terapeutiskt vaerdefull foerening.
GB9111732D0 (en) * 1991-05-31 1991-07-24 Orion Yhtymae Oy The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs
GB2281206A (en) * 1993-08-25 1995-03-01 Orion Yhtymae Oy Use of dexmedetomidine
RU2157210C2 (ru) * 1995-12-28 2000-10-10 Проктер энд Гэмбл Компани Замещенные 6h-1,3,4-тиадиазин-2-амины, их применение в качестве анестезирующих, сердечно-сосудистых и гипометаболических средств и содержащие их фармацевтические композиции
EP0877025B1 (en) * 1995-12-28 2001-10-17 The Procter & Gamble Company Substituted 6-h-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetising, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them
EP0877024B1 (en) 1995-12-28 2002-02-20 Nauchno-Tekhnologicheskoe Predpriyatie "Ligand" (Obschestvo S Ogranichennoi Otvetstvennostju) Substituted 6-h-1,3,4-thiadiazine-2-amines, the use thereof as an aesthetising, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them
AU5127996A (en) * 1995-12-28 1997-07-28 Procter & Gamble Company, The Substituted 6-r-1,3,4-thiadiazine-2-amines, the use thereof as anaesthetising, cardiovascular and hypometabolic agents, and a pharmaceutical composition containing them
AR015744A1 (es) * 1998-04-01 2001-05-16 Orion Corp Uso de dexmedetomidina para sedacion en terapia intensiva
RU2008130448A (ru) 2006-01-27 2010-03-10 Ф. Хоффманн-Ля Рош Аг (Ch) Применение производных 4-имидазола для расстройств цнс
RU2009112496A (ru) 2006-10-19 2010-11-27 Ф. Хоффманн-Ля Рош Аг (Ch) Аминометил-4-имидазолы
CA2668454A1 (en) 2006-11-02 2008-05-08 F. Hoffmann-La Roche Ag Substituted 2-imidazoles
JP2010510184A (ja) 2006-11-16 2010-04-02 エフ．ホフマン−ラ ロシュ アーゲー 置換４−イミダゾール類
CA2672617A1 (en) 2006-12-13 2008-06-19 F. Hoffmann-La Roche Ag Novel 2-imidazoles as ligands for trace amine associated receptors (taar)
US20080146523A1 (en) 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
CN101600700B (zh) 2007-02-02 2013-08-21 弗·哈夫曼-拉罗切有限公司 作为taar1配体用于cns病症的新的2-氨基噁唑啉
KR101222412B1 (ko) 2007-02-15 2013-01-15 에프. 호프만-라 로슈 아게 Ｔａａｒ1 리간드로서의 2-아미노옥사졸린
CN101687812A (zh) 2007-07-02 2010-03-31 弗·哈夫曼-拉罗切有限公司 对痕量胺相关受体(taar)具有良好亲和性的2-咪唑啉化合物
CA2691704A1 (en) 2007-07-03 2009-01-08 F. Hoffmann-La Roche Ag 4-imidazolines and their use as antidepressants
CA2694362A1 (en) 2007-07-27 2009-02-05 F. Hoffmann-La Roche Ag 2-azetidinemethaneamines and 2-pyrrolidinemethaneamines as taar-ligands
JP5341084B2 (ja) 2007-08-03 2013-11-13 エフ．ホフマン−ラ ロシュ アーゲー Ｔａａｒ１リガンドとしてのピリジンカルボキシアミド及びベンズアミド誘導体
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
ES2733905T3 (es) * 2009-02-13 2019-12-03 Allergan Inc Composiciones farmacéuticas que comprenden (3-(1-(1H-imidazol-4-il)etil)-2-metilfenil)metanol
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
AU2012340806B2 (en) 2011-11-21 2017-10-19 Allergan, Inc. Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3H-imidazole derivatives for treating retinal diseases
CA2924236C (en) 2013-10-07 2020-01-07 Teikoku Pharma Usa, Inc. Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
KR101948779B1 (ko) 2013-10-07 2019-05-21 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치 및 이의 사용 방법
CA2924233C (en) 2013-10-07 2018-10-23 Teikoku Pharma Usa, Inc. Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions
CN108713019B (zh) 2016-03-17 2021-06-15 豪夫迈·罗氏有限公司 具有作为taar的激动剂的活性的5-乙基-4-甲基-吡唑-3-甲酰胺衍生物
BR112019006955A2 (pt) 2016-10-31 2019-07-02 Teikoku Pharma Usa Inc métodos de controle da dor usando dispositivos de distribuição transdérmica de dexmedetomidina
US12472158B2 (en) 2019-02-27 2025-11-18 Vanderbilt University Methods of treating trigeminal nerve pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202660A (en) 1961-10-09 1965-08-24 Boehringer Sohn Ingelheim Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
FI844786A0 (fi) * 1984-12-04 1984-12-04 Farmos Oy Terapeutiskt utnyttjbar foerening.
FI864570A0 (fi) * 1986-11-11 1986-11-11 Farmos Oy Terapeutiskt anvaendbar foerening.
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative

Also Published As

Publication number Publication date
HUT51139A (en) 1990-04-28
ZA891493B (en) 1989-11-29
HU202751B (en) 1991-04-29
EP0331374A2 (en) 1989-09-06
JP2856410B2 (ja) 1999-02-10
GB2215206A (en) 1989-09-20
DE68913054D1 (de) 1994-03-24
EP0331374A3 (en) 1990-10-10
DK46489A (da) 1989-08-30
KR890012647A (ko) 1989-09-18
CA1338556C (en) 1996-08-27
KR0136790B1 (ko) 1998-04-25
GB2215206B (en) 1991-07-03
EP0331374B1 (en) 1994-02-16
DK175282B1 (da) 2004-08-09
JPH01294623A (ja) 1989-11-28
IE60538B1 (en) 1994-07-27
IE890639L (en) 1989-08-29
ATE101514T1 (de) 1994-03-15
DE68913054T2 (de) 1994-07-07
NZ228125A (en) 1996-12-20
GB8804683D0 (en) 1988-03-30
AU611262B2 (en) 1991-06-06
AU3027289A (en) 1989-08-31

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