DK46489D0 - Anvendelse af 4-(1-(2,3-dimetylfenyl)-aetyl)-1h-imidazol til fremstilling af laegemidler til perioperativ anvendelse - Google Patents

Anvendelse af 4-(1-(2,3-dimetylfenyl)-aetyl)-1h-imidazol til fremstilling af laegemidler til perioperativ anvendelse

Info

Publication number
DK46489D0
DK46489D0 DK046489A DK46489A DK46489D0 DK 46489 D0 DK46489 D0 DK 46489D0 DK 046489 A DK046489 A DK 046489A DK 46489 A DK46489 A DK 46489A DK 46489 D0 DK46489 D0 DK 46489D0
Authority
DK
Denmark
Prior art keywords
dimethylphenyl
imidazole
ethyl
preparation
medicinal products
Prior art date
Application number
DK046489A
Other languages
English (en)
Other versions
DK175282B1 (da
DK46489A (da
Inventor
Mervyn Maze
Mika Scheinin
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of DK46489D0 publication Critical patent/DK46489D0/da
Publication of DK46489A publication Critical patent/DK46489A/da
Application granted granted Critical
Publication of DK175282B1 publication Critical patent/DK175282B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK198900464A 1988-02-29 1989-02-02 Anvendelse af 4-[1-(2,3-dimetylfenyl)-ætyl]-1H-imidazol til fremstilling af lægemidler til perioperativ anvendelse DK175282B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8804683A GB2215206B (en) 1988-02-29 1988-02-29 4-substituted imidazole derivatives useful in perioperative care
GB8804683 1988-02-29

Publications (3)

Publication Number Publication Date
DK46489D0 true DK46489D0 (da) 1989-02-02
DK46489A DK46489A (da) 1989-08-30
DK175282B1 DK175282B1 (da) 2004-08-09

Family

ID=10632543

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900464A DK175282B1 (da) 1988-02-29 1989-02-02 Anvendelse af 4-[1-(2,3-dimetylfenyl)-ætyl]-1H-imidazol til fremstilling af lægemidler til perioperativ anvendelse

Country Status (13)

Country Link
EP (1) EP0331374B1 (da)
JP (1) JP2856410B2 (da)
KR (1) KR0136790B1 (da)
AT (1) ATE101514T1 (da)
AU (1) AU611262B2 (da)
CA (1) CA1338556C (da)
DE (1) DE68913054T2 (da)
DK (1) DK175282B1 (da)
GB (1) GB2215206B (da)
HU (1) HU202751B (da)
IE (1) IE60538B1 (da)
NZ (1) NZ228125A (da)
ZA (1) ZA891493B (da)

Families Citing this family (31)

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FI894911A0 (fi) * 1989-10-17 1989-10-17 Farmos Oy En terapeutiskt vaerdefull foerening.
GB9111732D0 (en) * 1991-05-31 1991-07-24 Orion Yhtymae Oy The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs
GB2281206A (en) * 1993-08-25 1995-03-01 Orion Yhtymae Oy Use of dexmedetomidine
ES2165930T3 (es) * 1995-12-28 2002-04-01 N T Predpr Ligand Obschestvo S 6-h-1,3,4-tiadiazin-2-amina sustituidos, su empleo como agentes anestesicos, cardiovasculares e hipometabolicos, y composicion farmaceutica que los contiene.
DE69523640T2 (de) * 1995-12-28 2002-11-21 Nauchno-Tekhnologicheskoe Predpriyatie "Ligand" (Obschestvo S Ogranichennoi Otvetstvennostju), Ekaterinburg Substituierte 6-r-1,3,4-thiadiazin-2-amine, deren verwendung als anaesthetische, cardiovaskulare und hypometabolische mittel, und eine sie enthaltende pharmazeutische zubereitung
ES2172606T3 (es) 1995-12-28 2002-10-01 N T Predpr Ligand Obschestvo S 6-h-1,3,4-tiadiazin-2-aminas, su uso como agentes anestesicos, cardiovasculares e hipometabolicos, y una composicion farmaceutica que las contiene.
RU2157210C2 (ru) * 1995-12-28 2000-10-10 Проктер энд Гэмбл Компани Замещенные 6h-1,3,4-тиадиазин-2-амины, их применение в качестве анестезирующих, сердечно-сосудистых и гипометаболических средств и содержащие их фармацевтические композиции
AR015744A1 (es) * 1998-04-01 2001-05-16 Orion Corp Uso de dexmedetomidina para sedacion en terapia intensiva
KR101079914B1 (ko) * 2006-01-27 2011-11-04 에프. 호프만-라 로슈 아게 중추신경계 장애를 위한 4-이미다졸 유도체의 용도
AU2007312390B2 (en) 2006-10-19 2013-03-28 F. Hoffmann-La Roche Ag Aminomethyl-4-imidazoles
AU2007316257A1 (en) 2006-11-02 2008-05-08 F. Hoffmann-La Roche Ag Substituted 2-imidazoles as modulators of the trace amine associated receptors
WO2008058867A2 (en) 2006-11-16 2008-05-22 F. Hoffmann-La Roche Ag Substituted 4-imidazoles
KR101189348B1 (ko) 2006-12-13 2012-10-09 에프. 호프만-라 로슈 아게 미량 아민 결합 수용체(ｔａａｒ)에 대한 리간드로서의 신규한 2-이미다졸
US20080146523A1 (en) 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
ES2510546T3 (es) 2007-02-02 2014-10-21 F. Hoffmann-La Roche Ag Nuevas 2-aminooxazolinas como ligandos TAAR1 para trastornos del SNC
MX2009008465A (es) 2007-02-15 2009-08-20 Hoffmann La Roche Nuevas 2-aminooxazolinas como ligandos de taar1.
CN101687812A (zh) 2007-07-02 2010-03-31 弗·哈夫曼-拉罗切有限公司 对痕量胺相关受体(taar)具有良好亲和性的2-咪唑啉化合物
KR101150628B1 (ko) 2007-07-03 2012-05-31 에프. 호프만-라 로슈 아게 4-이미다졸린 및 항우울제로서 이의 용도
CN101765587A (zh) 2007-07-27 2010-06-30 弗·哈夫曼-拉罗切有限公司 作为taar配体的2-氮杂环丁烷甲胺类和2-吡咯烷甲胺类
KR101167773B1 (ko) 2007-08-03 2012-07-24 에프. 호프만-라 로슈 아게 Ｔａａｒ１ 리간드로서의 피리딘카복스아마이드 및 벤즈아마이드 유도체
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
EP2395999B1 (en) 2009-02-13 2017-09-13 Allergan, Inc. Pharmaceutical compositions comprising (3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl)methanol
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
WO2013078151A1 (en) 2011-11-21 2013-05-30 Allergan, Inc. Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3h-imidazole derivatives for treating retinal diseases
RU2018105761A (ru) 2013-10-07 2019-02-26 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Устройства для трансдермальной доставки дексмедетомидина и способы их применения
TWI709417B (zh) 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
RU2648449C2 (ru) 2013-10-07 2018-03-26 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Способы и композиции для трансдермальной доставки неседативного количества дексмедетомидина
MY195528A (en) 2016-03-17 2023-01-30 Hoffmann La Roche 5-Ethyl-4-Methyl-Pyrazole-3-Carboxamide Derivative Having Activity as Agonist of Taar
KR20210113439A (ko) * 2016-10-31 2021-09-15 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 전달 장치를 이용한 통증을 관리하는 방법
WO2020176807A1 (en) 2019-02-27 2020-09-03 Vanderbilt University Methods of treating trigeminal nerve pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202660A (en) 1961-10-09 1965-08-24 Boehringer Sohn Ingelheim Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
FI844786A0 (fi) * 1984-12-04 1984-12-04 Farmos Oy Terapeutiskt utnyttjbar foerening.
FI864570A0 (fi) * 1986-11-11 1986-11-11 Farmos Oy Terapeutiskt anvaendbar foerening.
GB2206880B (en) * 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative

Also Published As

Publication number Publication date
CA1338556C (en) 1996-08-27
JP2856410B2 (ja) 1999-02-10
DE68913054D1 (de) 1994-03-24
AU3027289A (en) 1989-08-31
JPH01294623A (ja) 1989-11-28
IE60538B1 (en) 1994-07-27
EP0331374A2 (en) 1989-09-06
NZ228125A (en) 1996-12-20
DK175282B1 (da) 2004-08-09
ATE101514T1 (de) 1994-03-15
GB8804683D0 (en) 1988-03-30
DK46489A (da) 1989-08-30
GB2215206A (en) 1989-09-20
IE890639L (en) 1989-08-29
EP0331374A3 (en) 1990-10-10
KR890012647A (ko) 1989-09-18
DE68913054T2 (de) 1994-07-07
AU611262B2 (en) 1991-06-06
HUT51139A (en) 1990-04-28
HU202751B (en) 1991-04-29
ZA891493B (en) 1989-11-29
GB2215206B (en) 1991-07-03
EP0331374B1 (en) 1994-02-16
KR0136790B1 (ko) 1998-04-25

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