DK48187D0 - 5,6-dihydro-2-(substitueret phenyl)-1,2,4-triazin-3,5(2h, 4h)-dioner - Google Patents

5,6-dihydro-2-(substitueret phenyl)-1,2,4-triazin-3,5(2h, 4h)-dioner

Info

Publication number
DK48187D0
DK48187D0 DK048187A DK48187A DK48187D0 DK 48187 D0 DK48187 D0 DK 48187D0 DK 048187 A DK048187 A DK 048187A DK 48187 A DK48187 A DK 48187A DK 48187 D0 DK48187 D0 DK 48187D0
Authority
DK
Denmark
Prior art keywords
compounds
diones
dihydro
substituted phenyl
triazin
Prior art date
Application number
DK048187A
Other languages
English (en)
Other versions
DK48187A (da
DK169032B1 (da
Inventor
Gustaaf Maria Boeckx
Alfons Herman Marg Raeymaekers
Victor Sipido
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK48187D0 publication Critical patent/DK48187D0/da
Publication of DK48187A publication Critical patent/DK48187A/da
Application granted granted Critical
Publication of DK169032B1 publication Critical patent/DK169032B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
DK048187A 1986-01-30 1987-01-29 5,6-dihydro-2-(substitueret phenyl)-1,2,4-triazin-3,5(2H, 4H)-dioner, fremgangsmåde til fremstilling deraf og præparater indeholdende disse forbindelser DK169032B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8602342 1986-01-30
GB868602342A GB8602342D0 (en) 1986-01-30 1986-01-30 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones

Publications (3)

Publication Number Publication Date
DK48187D0 true DK48187D0 (da) 1987-01-29
DK48187A DK48187A (da) 1987-07-31
DK169032B1 DK169032B1 (da) 1994-08-01

Family

ID=10592258

Family Applications (2)

Application Number Title Priority Date Filing Date
DK048187A DK169032B1 (da) 1986-01-30 1987-01-29 5,6-dihydro-2-(substitueret phenyl)-1,2,4-triazin-3,5(2H, 4H)-dioner, fremgangsmåde til fremstilling deraf og præparater indeholdende disse forbindelser
DK065193A DK65193A (da) 1986-01-30 1993-06-04 4,5-dihydro-2-(substitueret phenyl)-1,2,4-triazin-3,5(3h)-dionforbindelser, fremgangsmaade til fremstilling deraf samt praeparater indeholdende disse forbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK065193A DK65193A (da) 1986-01-30 1993-06-04 4,5-dihydro-2-(substitueret phenyl)-1,2,4-triazin-3,5(3h)-dionforbindelser, fremgangsmaade til fremstilling deraf samt praeparater indeholdende disse forbindelser

Country Status (21)

Country Link
US (3) US4767760A (da)
EP (1) EP0232932B1 (da)
JP (2) JPH0813806B2 (da)
CN (1) CN1017049B (da)
AT (1) ATE59644T1 (da)
AU (1) AU586731B2 (da)
CA (2) CA1288772C (da)
DE (1) DE3766839D1 (da)
DK (2) DK169032B1 (da)
ES (1) ES2031876T3 (da)
FI (1) FI94634C (da)
GB (1) GB8602342D0 (da)
GR (1) GR3001392T3 (da)
IE (1) IE59510B1 (da)
IL (1) IL81421A (da)
NO (1) NO172690C (da)
NZ (1) NZ218973A (da)
PT (1) PT84218B (da)
RU (1) RU2017736C1 (da)
SU (1) SU1595339A3 (da)
ZA (1) ZA87672B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097779A (en) * 1976-04-05 1978-06-27 Gte Sylvania Incorporated Fluorescent lamp containing a cathode heater circuit disconnect device
US4156831A (en) * 1978-05-24 1979-05-29 Gte Sylvania Incorporated Fluorescent lamp having heater circuit disconnect device
GB8602342D0 (en) * 1986-01-30 1986-03-05 Janssen Pharmaceutica Nv 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones
DE3826058A1 (de) * 1988-07-30 1990-02-08 Bayer Ag Mittel gegen fischparasiten
ES2058463T3 (es) * 1989-01-09 1994-11-01 Bayer Ag Agentes contra protozoos en insectos.
EP0377903A3 (de) * 1989-01-09 1991-07-17 Bayer Ag Substituierte Hexahydro-1,2,4-triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
CN1044905A (zh) * 1989-02-16 1990-08-29 赫彻斯特股份公司 鱼和昆虫寄生虫对抗剂
CA2012004A1 (en) * 1989-03-15 1990-09-15 Frank Ellis Chemical compounds
EP0476439A1 (de) * 1990-09-18 1992-03-25 Bayer Ag Substituierte 1,2,4-Triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung
DE4120138A1 (de) * 1991-06-19 1992-12-24 Bayer Ag Substituierte hexahydro-1,2,4-triazindione, verfahren zu ihrer herstellung, zwischenprodukte dafuer und ihre verwendung
US5994355A (en) 1993-10-15 1999-11-30 Takeda Chemical Industries, Ltd. 1, 2, 4-Triazin-3-one derivatives, production and use thereof
TW403741B (en) * 1993-10-15 2000-09-01 Takeda Chemical Industries Ltd Triazine derivative, production and use thereof
DE69615601T2 (de) * 1995-04-14 2002-07-11 Takeda Schering-Plough Animal Health K.K., Osaka Verfahren zur Herstellung von Triazinderivate
US5747476A (en) * 1996-07-17 1998-05-05 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoal myeloencephalitis
EP0831088B1 (en) * 1996-08-30 2002-11-27 Takeda Schering-Plough Animal Health K.K. 1,2,4-Triazine-3,5-dione derivatives as anticoccidial agents
US5883095A (en) * 1997-08-07 1999-03-16 University Of Kentucky Research Foundation Formulations and methods to treat and prevent equine protozoal myeloencephalitis
BR9808114A (pt) * 1997-03-31 2000-03-08 David Granstrom Formulação de ração para cavalos utilizável para tratar epm, processos para tratar pm em um cavalo que necessita deste tratamento, para prevenir infecção com s. neutrona em cavalos, e, para exterminar s. neurona em cavalos
US5830893A (en) * 1997-04-23 1998-11-03 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoan myeloencephalitis using triazinediones
US6867207B2 (en) * 1997-07-10 2005-03-15 Janssen Pharmaceutica N.V. IL-5 inhibiting 6-azauracil derivatives
HRP20000003A2 (en) * 1997-07-10 2000-12-31 Janssen Pharmaceutica Nv Il-5 inhibiting 6-azauracil derivatives
CN1261881A (zh) 1997-07-10 2000-08-02 詹森药业有限公司 作为il－5－抑制剂的6－氮杂尿嘧啶衍生物
TW450964B (en) 1997-08-29 2001-08-21 Takeda Schering Plough Animal Triazine derivatives, their production and use
AU9017198A (en) * 1998-07-27 2000-02-21 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoan myeloencephalitis using triazinediones
EP0987265A1 (en) 1998-09-18 2000-03-22 Janssen Pharmaceutica N.V. Interleukin-5 inhibiting 6-azauracil derivatives
MXPA01003542A (es) * 1998-10-08 2002-09-18 New Ace Res Company Composiciones y metodos nuevos para la prevencion y tratamiento de enfermedad causada por protozoarios.
EA004806B1 (ru) * 1998-12-18 2004-08-26 Янссен Фармацевтика Н.В. Производные 6-азаурацила, ингибирующие il-5
CZ2002356A3 (cs) 1999-08-06 2002-06-12 Janssen Pharmaceutica N. V. Deriváty 6-azauracilu inhibující interleukin-5
PA8591801A1 (es) * 2002-12-31 2004-07-26 Pfizer Prod Inc Inhibidores benzamidicos del receptor p2x7.
GB0622472D0 (en) * 2006-11-10 2006-12-20 Addex Pharmaceuticals Sa Novel heterocyclic derivatives
CN107746390B (zh) * 2017-11-21 2021-03-16 连云港市亚晖医药化工有限公司 抗球虫药地克珠利的制备方法
CN113999139A (zh) * 2021-12-03 2022-02-01 杭州臻峰科技有限公司 制备2，6-二氯-α-（4-氯代苯基） -4-硝基苯乙腈的方法
CN119161311B (zh) * 2024-11-20 2025-02-11 北京纳百生物科技有限公司 一种地克珠利抗原及其合成方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3912723A (en) * 1971-03-29 1975-10-14 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
US3905971A (en) * 1971-03-29 1975-09-16 Pfizer 2-Phenyl-as-triazine-3,5(2H,4H)diones
GB1448696A (en) * 1973-05-29 1976-09-08 Pfizer 2-phqnyl-astriazine-3,4-2h,4h-diones
DE3408924A1 (de) * 1984-03-12 1985-09-26 Hoechst Ag, 6230 Frankfurt Substituierte 2-phenyl-hexahydro-1,2,4-triazin-3,5-dione, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
CA1244024A (en) * 1984-08-01 1988-11-01 Gustaaf M. Boeckx .alpha.- ARYL-4-(4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZIN- 2(3H)-YL)BENZENEACETONITRILES
US4631278A (en) * 1984-08-01 1986-12-23 Janssen Pharmaceutica N.V. Anti-protozoal α-aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-benzeneacetonitrile derivatives, pharmaceutical compositions, and method of use therefor
GB8602342D0 (en) * 1986-01-30 1986-03-05 Janssen Pharmaceutica Nv 5 6-dihydro-2-(substituted phenyl)-1 2 4-triazine-3 5(2h 4h)-diones

Also Published As

Publication number Publication date
GR3001392T3 (en) 1992-09-11
US4767760A (en) 1988-08-30
FI94634C (fi) 1995-10-10
US4952570A (en) 1990-08-28
DK48187A (da) 1987-07-31
IE59510B1 (en) 1994-03-09
AU6813487A (en) 1987-08-06
ZA87672B (en) 1988-09-28
CA1302411C (en) 1992-06-02
JP2622510B2 (ja) 1997-06-18
GB8602342D0 (en) 1986-03-05
IE870231L (en) 1987-07-30
EP0232932A1 (en) 1987-08-19
AU586731B2 (en) 1989-07-20
PT84218A (en) 1987-02-01
FI870421A7 (fi) 1987-07-31
ES2031876T3 (es) 1993-01-01
NO870378L (no) 1987-07-31
PT84218B (pt) 1989-07-31
SU1595339A3 (ru) 1990-09-23
DK65193D0 (da) 1993-06-04
NO870378D0 (no) 1987-01-29
JPS62190174A (ja) 1987-08-20
JPH0813806B2 (ja) 1996-02-14
CN87100531A (zh) 1987-09-02
NO172690C (no) 1993-08-25
JPH07285949A (ja) 1995-10-31
DK169032B1 (da) 1994-08-01
FI870421A0 (fi) 1987-01-30
ATE59644T1 (de) 1991-01-15
EP0232932B1 (en) 1991-01-02
RU2017736C1 (ru) 1994-08-15
DE3766839D1 (de) 1991-02-07
US4912106A (en) 1990-03-27
CA1288772C (en) 1991-09-10
NZ218973A (en) 1988-10-28
IL81421A (en) 1991-11-21
FI94634B (fi) 1995-06-30
DK65193A (da) 1993-06-04
IL81421A0 (en) 1987-08-31
CN1017049B (zh) 1992-06-17
NO172690B (no) 1993-05-18

Similar Documents

Publication Publication Date Title
DK48187A (da) 5,6-dihydro-2-(substitueret phenyl)-1,2,4-triazin-3,5(2h, 4h)-dioner
DE69008366D1 (de) 2-Aminopyrimidinon-Derivate.
DK74691A (da) 4(4-(substitueret phenyl)-1-piperazinyl)phenoler og fremgangsmaade til fremstilling deraf
FI913433A0 (fi) Foerfarande foer foerhindrande eller begraensande av skada vid aoterstroemning av blod genom ett organ eller en vaevnad.
KR960009422B1 (en) 4-(ardylamino)piperidinebutanamide derivatives
ATE124410T1 (de) Antihypertensive 3-piperidinylindazol-derivate.

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed