DK516485A - Fremgangsmaade til spaltning af peptider og proteiner ved methionyl-bindingen - Google Patents

Fremgangsmaade til spaltning af peptider og proteiner ved methionyl-bindingen Download PDF

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Publication number
DK516485A
DK516485A DK516485A DK516485A DK516485A DK 516485 A DK516485 A DK 516485A DK 516485 A DK516485 A DK 516485A DK 516485 A DK516485 A DK 516485A DK 516485 A DK516485 A DK 516485A
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DK
Denmark
Prior art keywords
peptides
proteins
methionyl
divoluting
bonding
Prior art date
Application number
DK516485A
Other languages
English (en)
Other versions
DK166546C (da
DK166546B (da
DK516485D0 (da
Inventor
Richard Bicker
Gerhard Seipke
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK516485D0 publication Critical patent/DK516485D0/da
Publication of DK516485A publication Critical patent/DK516485A/da
Publication of DK166546B publication Critical patent/DK166546B/da
Application granted granted Critical
Publication of DK166546C publication Critical patent/DK166546C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/126—Aminolysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK516485A 1984-11-09 1985-11-08 Fremgangsmaade til spaltning af peptider og proteiner ved methionyl-bindingen DK166546C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3440988 1984-11-09
DE19843440988 DE3440988A1 (de) 1984-11-09 1984-11-09 Verfahren zur spaltung von peptiden und proteinen an der methionyl-bindung

Publications (4)

Publication Number Publication Date
DK516485D0 DK516485D0 (da) 1985-11-08
DK516485A true DK516485A (da) 1986-05-10
DK166546B DK166546B (da) 1993-06-07
DK166546C DK166546C (da) 1993-10-25

Family

ID=6249917

Family Applications (1)

Application Number Title Priority Date Filing Date
DK516485A DK166546C (da) 1984-11-09 1985-11-08 Fremgangsmaade til spaltning af peptider og proteiner ved methionyl-bindingen

Country Status (15)

Country Link
US (1) US4644057A (da)
EP (1) EP0180920B1 (da)
JP (1) JPH0714960B2 (da)
KR (1) KR930007428B1 (da)
AT (1) ATE71109T1 (da)
AU (1) AU580348B2 (da)
CA (1) CA1247081A (da)
DE (2) DE3440988A1 (da)
DK (1) DK166546C (da)
ES (1) ES8701780A1 (da)
FI (1) FI85494C (da)
GR (1) GR852693B (da)
IE (1) IE58683B1 (da)
PT (1) PT81445B (da)
ZA (1) ZA858603B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4745178A (en) * 1987-04-22 1988-05-17 Eli Lilly And Company Process for selective peptide bond cleavage using sulfoxides and CF3 CO
DE3726655A1 (de) * 1987-08-11 1989-02-23 Hoechst Ag Verfahren zur isolierung basischer proteine aus proteingemischen, welche solche basischen proteine enthalten
US4945157A (en) * 1988-05-27 1990-07-31 University Of Florida Novel Extraction procedure for protein G
NZ239652A (en) 1990-09-05 1992-09-25 Hoechst Ag Hydrolysis of preproinsulin to insulin and analogues using clostripain and optionally carboxypeptidase
PT821006E (pt) 1996-07-26 2004-09-30 Aventis Pharma Gmbh Derivados de insulina com ligacao a zinco aumentada
DE19726167B4 (de) 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
US7193035B2 (en) * 2002-10-29 2007-03-20 Sanofi-Aventis Deutschland Gmbh Crystals of insulin analogs and processes for their preparation
ES2570937T3 (es) 2008-08-07 2016-05-23 Biocon Ltd Un proceso para la preparación de compuestos de insulina
PT3228320T (pt) 2008-10-17 2020-03-26 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
PH12011502708B1 (en) 2009-07-06 2017-11-10 Sanofi Aventis Deutschland Insulin preparations containing methionine
SG10201500871TA (en) 2009-11-13 2015-04-29 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist and methionine
JP5832439B2 (ja) 2009-11-13 2015-12-16 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト、インスリン及びメチオニンを含む薬学的組成物
CN103179978A (zh) 2010-08-30 2013-06-26 赛诺菲-安万特德国有限公司 Ave0010用于制造供治疗2型糖尿病用的药物的用途
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
JP6367115B2 (ja) 2011-08-29 2018-08-01 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病患者の血糖コントロールに使用する組合せ医薬
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE337223B (da) * 1967-05-23 1971-08-02 Pharmacia Ab
US3935072A (en) * 1972-08-10 1976-01-27 Tanabe Seiyaku Co., Ltd. Purification of coenzyme A
US3876501A (en) * 1973-05-17 1975-04-08 Baxter Laboratories Inc Binding enzymes to activated water-soluble carbohydrates
US3919049A (en) * 1974-06-27 1975-11-11 Tokyo Tanabe Co Process for preparing {62 -galactosidase
SE8302758L (sv) * 1983-05-17 1984-11-18 Pharmacia Ab Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening
GB8317697D0 (en) * 1983-06-29 1983-08-03 Shell Int Research Dissolution of peptides in non-aqueous and mixed non-aqueous/aqueous solvents
US4496689A (en) * 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer

Also Published As

Publication number Publication date
KR860003832A (ko) 1986-06-13
ZA858603B (en) 1986-07-30
ES8701780A1 (es) 1986-12-01
DK166546C (da) 1993-10-25
PT81445B (pt) 1987-12-30
PT81445A (de) 1985-12-01
US4644057A (en) 1987-02-17
DK166546B (da) 1993-06-07
DE3585078D1 (de) 1992-02-13
JPS61115096A (ja) 1986-06-02
EP0180920B1 (de) 1992-01-02
ATE71109T1 (de) 1992-01-15
FI854383L (fi) 1986-05-10
EP0180920A2 (de) 1986-05-14
DE3440988A1 (de) 1986-07-10
IE852795L (en) 1986-05-09
IE58683B1 (en) 1993-11-03
GR852693B (da) 1986-03-10
EP0180920A3 (en) 1989-01-04
ES548617A0 (es) 1986-12-01
AU4971385A (en) 1986-05-15
FI85494C (fi) 1992-04-27
AU580348B2 (en) 1989-01-12
CA1247081A (en) 1988-12-20
FI854383A0 (fi) 1985-11-07
JPH0714960B2 (ja) 1995-02-22
KR930007428B1 (ko) 1993-08-10
FI85494B (fi) 1992-01-15
DK516485D0 (da) 1985-11-08

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