DK529685A - Antibiotica og anti-tumormidler ll-e33288-kompleks - Google Patents

Antibiotica og anti-tumormidler ll-e33288-kompleks Download PDF

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Publication number
DK529685A
DK529685A DK529685A DK529685A DK529685A DK 529685 A DK529685 A DK 529685A DK 529685 A DK529685 A DK 529685A DK 529685 A DK529685 A DK 529685A DK 529685 A DK529685 A DK 529685A
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DK
Denmark
Prior art keywords
complex
antibiotica
tumor agents
nrrl
micromonospora
Prior art date
Application number
DK529685A
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English (en)
Other versions
DK168388B1 (da
DK529685D0 (da
Inventor
M D-M Lee
M Greenstein
D P Labeda
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DK529685D0 publication Critical patent/DK529685D0/da
Publication of DK529685A publication Critical patent/DK529685A/da
Application granted granted Critical
Publication of DK168388B1 publication Critical patent/DK168388B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Hydrogenated Pyridines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK529685A 1984-11-16 1985-11-15 Forbindelser i antibiotikumkompleks LL-E33288, lægemidler indeholdende disse forbindelser og mikroorganismekultur til brug ved deres fremstilling DK168388B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US67203184A 1984-11-16 1984-11-16
US67203184 1984-11-16
US78706685A 1985-10-17 1985-10-17
US78706685 1985-10-17

Publications (3)

Publication Number Publication Date
DK529685D0 DK529685D0 (da) 1985-11-15
DK529685A true DK529685A (da) 1986-05-17
DK168388B1 DK168388B1 (da) 1994-03-21

Family

ID=27100668

Family Applications (1)

Application Number Title Priority Date Filing Date
DK529685A DK168388B1 (da) 1984-11-16 1985-11-15 Forbindelser i antibiotikumkompleks LL-E33288, lægemidler indeholdende disse forbindelser og mikroorganismekultur til brug ved deres fremstilling

Country Status (19)

Country Link
EP (1) EP0182152B1 (da)
JP (1) JPH0774228B2 (da)
KR (1) KR890001289B1 (da)
AT (1) ATE180513T1 (da)
AU (1) AU589918B2 (da)
CA (1) CA1291054C (da)
DE (1) DE3588213T2 (da)
DK (1) DK168388B1 (da)
EG (1) EG17709A (da)
ES (1) ES8703160A1 (da)
FI (1) FI86892C (da)
GR (1) GR852725B (da)
HU (1) HU195855B (da)
IL (7) IL76878A (da)
LV (1) LV12523B (da)
MX (1) MX9203146A (da)
NO (1) NO163574C (da)
NZ (1) NZ214114A (da)
PT (1) PT81493B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3440423A1 (de) * 1984-11-06 1986-05-07 Dr. Karl Thomae Gmbh, 7950 Biberach Antibiotisches polypeptid, verfahren zu seiner herstellung, dieses polypeptid erzeugender stamm von staphylococcus epidermidis, dieses polypeptid enthaltende zubereitungsformen und seine verwendung zur bekaempfung infektioeser erkrankungen
US5024948A (en) * 1985-10-17 1991-06-18 American Cyanamid Company Genetic system for micromonospora
EP0276485B1 (en) * 1987-01-30 2002-06-12 American Cyanamid Company Dihydro derivatives of LL-E33288 antibiotics
US4980297A (en) * 1987-02-27 1990-12-25 Becton, Dickinson And Company Device for the membrane separation of the components of a liquid sample
ATE112172T1 (de) * 1987-10-30 1994-10-15 American Cyanamid Co Targetformer von antitumor-methyltrithioagenzien.
US4977143A (en) * 1988-02-29 1990-12-11 American Cyanamid Company Antibacterial and antitumor agents LL-E33288EPSILON-I and LL-E33288EPSILON-BR
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
EP0330874A3 (en) * 1988-02-29 1989-10-18 American Cyanamid Company Antibacterial and antitumor agents LL-E33288 epsilon-I and LL-E33288-epsilonBr, with processes and intermediates for producing said agents
US4978748A (en) * 1988-02-29 1990-12-18 American Cyanamid Company Intermediate and process for producing the antibacterial and antitumor agents LL-E33288ε-I and LL-E33288Epsilon-Br
EP0342341A3 (en) * 1988-05-17 1991-07-24 American Cyanamid Company Process for producing antitumor antibiotic ll-e33288gamma2
IL94540A0 (en) * 1989-06-29 1991-03-10 American Cyanamid Co Antibiotic ll-e19085
CN109553646A (zh) * 2019-01-21 2019-04-02 浙江海正药业股份有限公司 一种纯化卡里奇霉素的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU515150B2 (en) * 1975-02-18 1981-03-19 Sterling Drug Inc. Preparation of aminocyclitol antibiotics
US4692333A (en) * 1982-08-26 1987-09-08 Gruppo Lepetit S.P.A. Antimicrobial and antitumor antibiotic M 9026 and its pure individual factors 1, 2, and 3 and microbial process for production thereof
US4843008A (en) * 1984-12-24 1989-06-27 Yamanouchi Pharmaceutical Co., Ltd. Novel microorganisms and a novel process for producing antibiotics

Also Published As

Publication number Publication date
LV12523A (en) 2000-08-20
PT81493B (pt) 1987-11-11
NO163574B (no) 1990-03-12
LV12523B (en) 2000-11-20
EP0182152A3 (en) 1987-08-05
EP0182152B1 (en) 1999-05-26
IL93418A0 (en) 1990-11-29
NO163574C (no) 1990-06-20
FI86892B (fi) 1992-07-15
IL76878A0 (en) 1986-02-28
FI854510A0 (fi) 1985-11-15
HU195855B (en) 1988-07-28
IL93417A0 (en) 1990-11-29
JPH0774228B2 (ja) 1995-08-09
IL93416A0 (en) 1990-11-29
DK168388B1 (da) 1994-03-21
EP0182152A2 (en) 1986-05-28
MX9203146A (es) 1992-07-01
PT81493A (en) 1985-12-01
IL93421A0 (en) 1990-11-29
HUT41839A (en) 1987-05-28
DE3588213T2 (de) 1999-09-30
FI86892C (fi) 1992-10-26
DE3588213D1 (de) 1999-07-01
AU4995785A (en) 1986-05-22
ATE180513T1 (de) 1999-06-15
IL93420A0 (en) 1990-11-29
CA1291054C (en) 1991-10-22
ES548953A0 (es) 1987-02-16
NZ214114A (en) 1989-04-26
EG17709A (en) 1990-08-30
KR890001289B1 (ko) 1989-04-28
KR870004144A (ko) 1987-05-07
IL76878A (en) 1991-12-15
FI854510L (fi) 1986-05-17
DK529685D0 (da) 1985-11-15
GR852725B (da) 1986-03-19
NO854578L (no) 1986-05-20
AU589918B2 (en) 1989-10-26
ES8703160A1 (es) 1987-02-16
JPS61158928A (ja) 1986-07-18
HK1011385A1 (en) 1999-07-09
IL93419A0 (en) 1990-11-29

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