DK538888D0 - Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat - Google Patents

Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat

Info

Publication number: DK538888D0
Authority: DK; Denmark
Prior art keywords: preparation; castanosperminesters; pharmaceutical; pharmaceutical preparation; aids
Prior art date: 1987-09-29

Application number

DK538888A

Other languages

English (en)

Other versions

DK538888A (da

DK172788B1 (da

Inventor

Paul S Liu

Sai P Sunkara

Terry L Bowlin

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-29

Filing date

1988-09-28

Publication date

1988-09-28

1988-09-28 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1988-09-28 Publication of DK538888D0 publication Critical patent/DK538888D0/da

1989-03-30 Publication of DK538888A publication Critical patent/DK538888A/da

1999-07-19 Application granted granted Critical

1999-07-19 Publication of DK172788B1 publication Critical patent/DK172788B1/da

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
208000030507 AIDS Diseases 0.000 abstract 1
208000031886 HIV Infections Diseases 0.000 abstract 1
206010038997 Retroviral infections Diseases 0.000 abstract 1
DWBDMLGCCJIACZ-ODXJTPSBSA-N [(1s,6s,7s,8r,8ar)-1,7,8-trihydroxy-1,2,3,5,6,7,8,8a-octahydroindolizin-6-yl] benzoate Chemical class O([C@H]1CN2CC[C@@H]([C@@H]2[C@@H](O)[C@@H]1O)O)C(=O)C1=CC=CC=C1 DWBDMLGCCJIACZ-ODXJTPSBSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Virology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK198805388A 1987-09-29 1988-09-28 Anvendelse af castanosperminestere til fremstilling af et farmaceutisk præparat DK172788B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/102,070 US5004746A (en)	1987-09-29	1987-09-29	Anti-retroviral castanospermine esters
US10207087		1987-09-29

Publications (3)

Publication Number	Publication Date
DK538888D0 true DK538888D0 (da)	1988-09-28
DK538888A DK538888A (da)	1989-03-30
DK172788B1 DK172788B1 (da)	1999-07-19

Family

ID=22287973

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198805388A DK172788B1 (da)	1987-09-29	1988-09-28	Anvendelse af castanosperminestere til fremstilling af et farmaceutisk præparat

Country Status (12)

Country	Link
US (1)	US5004746A (da)
EP (1)	EP0309952B1 (da)
JP (1)	JP2761898B2 (da)
KR (1)	KR960009416B1 (da)
AT (1)	ATE107506T1 (da)
AU (1)	AU614993B2 (da)
DE (1)	DE3850335T2 (da)
DK (1)	DK172788B1 (da)
ES (1)	ES2058201T3 (da)
IE (1)	IE64311B1 (da)
PH (1)	PH24431A (da)
ZA (1)	ZA887160B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS63501925A (ja) *	1985-12-23	1988-08-04	フレツド　ハツチンソン　キヤンサ−　リサ−チ　センタ−	レトロウイルスの複製、感染及び疾病誘発の制御
US4952585A (en) *	1988-12-15	1990-08-28	Merrell Dow Pharmaceuticals Inc.	Castanospermine esters in the inhibition of tumor metastasis
US5214050A (en) *	1989-10-17	1993-05-25	Merrell Dow Pharmaceuticals Inc.	Esters of castanospermine in the treatment of cerebral malaria
ZA908134B (en) *	1989-10-17	1991-07-31	Merrell Dow Pharma	Esters of castanosperime in the treatment of cerebral malaria
GB8924292D0 (en) *	1989-10-27	1989-12-13	Novalal Ltd	The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5028614A (en) *	1990-03-30	1991-07-02	Merrell Dow Pharmaceuticals Inc.	Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors
GB9027433D0 (en) *	1990-12-18	1991-02-06	Merrell Dow Pharma	Anti-herpes castanospermine esters
US5939430A (en) *	1993-02-22	1999-08-17	Merrell Pharmaceuticals Inc.	Combinations of retroviral inhibitors
GB9303518D0 (en) *	1993-02-22	1993-04-07	Merrell Dow Pharma	Combinations of retroviral inhibitors
IT1269862B (it) *	1994-05-30	1997-04-15	Indena Spa	Alcaloidi da mappia foetida, loro uso e formulazioni che li contengono
US5959111A (en) *	1997-05-22	1999-09-28	Hoechst Marion Roussel, Inc.	Process for preparing 6-0-monoesters of castanospermine
JP2002502374A (ja) *	1997-05-22	2002-01-22	アベンティス・ファーマスーティカルズ・インコーポレイテッド	カスタノスペルミンの６−ｏ−モノエステルの製造法
GB0110832D0 (en) *	2001-05-03	2001-06-27	Virogen Ltd	Antiviral compounds
WO2006085141A2 (en) *	2004-08-13	2006-08-17	Migenix Inc.	Compositions and methods for treating or preventing hepadnaviridae infection
JP2008515816A (ja) *	2004-10-06	2008-05-15	ミジェニックスインコーポレイテッド	カスタノスペルミンを含有する、併用抗ウイルス組成物およびその使用方法
US20080138351A1 (en) *	2006-08-02	2008-06-12	United Therapeutics Corporation	Liposome treatment of viral infections
US20090252785A1 (en) *	2008-03-26	2009-10-08	University Of Oxford	Endoplasmic reticulum targeting liposomes
CN102427804A (zh) *	2009-03-27	2012-04-25	牛津大学之校长及学者	降低胆固醇水平的脂质体
EP4106752A4 (en)	2020-02-21	2024-03-20	Florida State University Research Foundation, Inc.	TREATMENT OF HUMAN CORONAVIRUS INFECTIONS USING ALPHA-GLUCOSIDASE-GLYCOPROTEIN PROCESSING INHIBITORS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS63501925A (ja) *	1985-12-23	1988-08-04	フレツド　ハツチンソン　キヤンサ−　リサ−チ　センタ−	レトロウイルスの複製、感染及び疾病誘発の制御
ZA883925B (en) *	1987-06-08	1989-02-22	Merrell Dow Pharma	Inhibitors of glycoprotein processing having anti-retroviral activity
CA1315276C (en) *	1987-07-02	1993-03-30	Paul S. Liu	Castanospermine esters and glycosides
US4952585A (en) *	1988-12-15	1990-08-28	Merrell Dow Pharmaceuticals Inc.	Castanospermine esters in the inhibition of tumor metastasis

1987
- 1987-09-29 US US07/102,070 patent/US5004746A/en not_active Expired - Lifetime
1988
- 1988-09-23 ZA ZA887160A patent/ZA887160B/xx unknown
- 1988-09-26 AU AU22802/88A patent/AU614993B2/en not_active Ceased
- 1988-09-26 ES ES88115778T patent/ES2058201T3/es not_active Expired - Lifetime
- 1988-09-26 DE DE3850335T patent/DE3850335T2/de not_active Expired - Fee Related
- 1988-09-26 EP EP88115778A patent/EP0309952B1/en not_active Expired - Lifetime
- 1988-09-26 AT AT88115778T patent/ATE107506T1/de not_active IP Right Cessation
- 1988-09-27 JP JP63239891A patent/JP2761898B2/ja not_active Expired - Fee Related
- 1988-09-28 IE IE293388A patent/IE64311B1/en not_active IP Right Cessation
- 1988-09-28 KR KR88012544A patent/KR960009416B1/ko not_active Expired - Fee Related
- 1988-09-28 DK DK198805388A patent/DK172788B1/da not_active IP Right Cessation
- 1988-09-29 PH PH37614A patent/PH24431A/en unknown

Also Published As

Publication number	Publication date
ES2058201T3 (es)	1994-11-01
EP0309952A3 (en)	1990-09-26
ZA887160B (en)	1989-05-30
JP2761898B2 (ja)	1998-06-04
AU2280288A (en)	1989-04-06
DK538888A (da)	1989-03-30
KR890004701A (ko)	1989-05-09
JPH01106821A (ja)	1989-04-24
US5004746A (en)	1991-04-02
AU614993B2 (en)	1991-09-19
DK172788B1 (da)	1999-07-19
IE64311B1 (en)	1995-07-26
PH24431A (en)	1990-06-25
ATE107506T1 (de)	1994-07-15
KR960009416B1 (en)	1996-07-19
DE3850335D1 (de)	1994-07-28
DE3850335T2 (de)	1994-10-13
EP0309952A2 (en)	1989-04-05
IE882933L (en)	1989-03-29
EP0309952B1 (en)	1994-06-22

Legal Events

Date	Code	Title	Description
2005-06-06	PBP	Patent lapsed	Country of ref document: DK

Publication	Publication Date	Title
DK538888A (da)	1989-03-30	Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat
FI862011A0 (fi)	1986-05-14	Terapeutiska nukleosider.
FI952302L (fi)	1995-05-11	Pyran-2-onit ja 5,6-dihydropyranonit, jotka ovat käyttökelpoisia HIV:n ja muiden retrovirusten hoidossa
DK441786A (da)	1987-03-18	Nucleosider, der kan anvendes terapeutisk
DK602988A (da)	1989-05-04	Nukleosidderivater med antiviral virkning og laegemiddelpraeparat indeholdende saadanne forbindelser
FI942112L (fi)	1994-05-06	AIDS:n hoidossa käyttökelpoisia HIV-proteaasi-inhibiittoreita
DK0509019T3 (da)	1999-04-19	Behandling af humane retrovirale infektioner med 2',3'-dideoxyinosin
DK162965C (da)	1992-06-01	Anvendelse af et difluornucleosid eller et farmaceutisk acceptabelt salt deraf til fremstilling af et laegemiddel til behandling af neoplasma
DK524788A (da)	1988-11-18	Anvendelse af morphin-antagonister til fremstilling af laegemidler med immunomodulerende og antiviral effekt, isaer til behandling af erhvervede immundefekt-tilstande
EP0296573A3 (en)	1990-07-04	Novel nucleosides, their preparation and pharmaceutical novel nucleosides, their preparation and pharmaceutical compositions compositions
GR3017656T3 (en)	1996-01-31	New substituted azetidinones as anti-inflammatory and antidegenerative agents.
DE3875769D1 (de)	1992-12-17	Therapeutische nukleoside.
DE69112192D1 (de)	1995-09-21	Antiherpes-Castanosperminester.
DK16389D0 (da)	1989-01-13	Anvendelse af en blanding til behandling af alopecia
DK707988D0 (da)	1988-12-20	Fremgangsmaade til at haemme virus
FI851365L (fi)	1985-10-06	Liposomer med inhalerbara allergener foer behandling av allergener, foerfarande foer deras framstaellning och dessa innehaollande laekemedel.
ES2037807T3 (es)	1993-07-01	Medicamentos que contienen en combinacion interferon y 1-desoxi-piperidinosas, procedimiento para su fabricacion y su aplicacion.
FI925209A0 (fi)	1992-11-17	Foerfarande foer framstaellning av terapeutiskt aktiva heterocykliskt substituerade foereningar