DK538888A - Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat - Google Patents

Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat

Info

Publication number: DK538888A
Authority: DK; Denmark
Prior art keywords: preparation; castanosperminesters; pharmaceutical; pharmaceutical preparation; aids
Prior art date: 1987-09-29

Application number

DK538888A

Other languages

English (en)

Other versions

DK538888D0 (da

DK172788B1 (da

Inventor

Paul S Liu

Sai P Sunkara

Terry L Bowlin

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-29

Filing date

1988-09-28

Publication date

1989-03-30

1988-09-28 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1988-09-28 Publication of DK538888D0 publication Critical patent/DK538888D0/da

1989-03-30 Publication of DK538888A publication Critical patent/DK538888A/da

1999-07-19 Application granted granted Critical

1999-07-19 Publication of DK172788B1 publication Critical patent/DK172788B1/da

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
208000030507 AIDS Diseases 0.000 abstract 1
208000031886 HIV Infections Diseases 0.000 abstract 1
206010038997 Retroviral infections Diseases 0.000 abstract 1
DWBDMLGCCJIACZ-ODXJTPSBSA-N [(1s,6s,7s,8r,8ar)-1,7,8-trihydroxy-1,2,3,5,6,7,8,8a-octahydroindolizin-6-yl] benzoate Chemical class O([C@H]1CN2CC[C@@H]([C@@H]2[C@@H](O)[C@@H]1O)O)C(=O)C1=CC=CC=C1 DWBDMLGCCJIACZ-ODXJTPSBSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Virology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK198805388A 1987-09-29 1988-09-28 Anvendelse af castanosperminestere til fremstilling af et farmaceutisk præparat DK172788B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10207087		1987-09-29
US07/102,070 US5004746A (en)	1987-09-29	1987-09-29	Anti-retroviral castanospermine esters

Publications (3)

Publication Number	Publication Date
DK538888D0 DK538888D0 (da)	1988-09-28
DK538888A true DK538888A (da)	1989-03-30
DK172788B1 DK172788B1 (da)	1999-07-19

Family

ID=22287973

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198805388A DK172788B1 (da)	1987-09-29	1988-09-28	Anvendelse af castanosperminestere til fremstilling af et farmaceutisk præparat

Country Status (12)

Country	Link
US (1)	US5004746A (da)
EP (1)	EP0309952B1 (da)
JP (1)	JP2761898B2 (da)
KR (1)	KR960009416B1 (da)
AT (1)	ATE107506T1 (da)
AU (1)	AU614993B2 (da)
DE (1)	DE3850335T2 (da)
DK (1)	DK172788B1 (da)
ES (1)	ES2058201T3 (da)
IE (1)	IE64311B1 (da)
PH (1)	PH24431A (da)
ZA (1)	ZA887160B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3650377T2 (de) *	1985-12-23	1996-02-22	Hutchinson Fred Cancer Res	Regulierung der retroviralen replikation, infektion und pathogenese.
US4952585A (en) *	1988-12-15	1990-08-28	Merrell Dow Pharmaceuticals Inc.	Castanospermine esters in the inhibition of tumor metastasis
AU628228B2 (en) *	1989-10-17	1992-09-10	Merrell Dow Pharmaceuticals Inc.	Esters of castanospermine in the treatment of cerebral malaria
US5214050A (en) *	1989-10-17	1993-05-25	Merrell Dow Pharmaceuticals Inc.	Esters of castanospermine in the treatment of cerebral malaria
GB8924292D0 (en) *	1989-10-27	1989-12-13	Novalal Ltd	The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5028614A (en) *	1990-03-30	1991-07-02	Merrell Dow Pharmaceuticals Inc.	Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors
GB9027433D0 (en) *	1990-12-18	1991-02-06	Merrell Dow Pharma	Anti-herpes castanospermine esters
US5939430A (en) *	1993-02-22	1999-08-17	Merrell Pharmaceuticals Inc.	Combinations of retroviral inhibitors
GB9303518D0 (en) *	1993-02-22	1993-04-07	Merrell Dow Pharma	Combinations of retroviral inhibitors
IT1269862B (it) *	1994-05-30	1997-04-15	Indena Spa	Alcaloidi da mappia foetida, loro uso e formulazioni che li contengono
US5959111A (en) *	1997-05-22	1999-09-28	Hoechst Marion Roussel, Inc.	Process for preparing 6-0-monoesters of castanospermine
CA2287316C (en) *	1997-05-22	2005-02-08	Hoechst Marion Roussel, Inc.	Process for preparing 6-o-monoesters of castanospermine
GB0110832D0 (en) *	2001-05-03	2001-06-27	Virogen Ltd	Antiviral compounds
US20060052414A1 (en) *	2004-08-13	2006-03-09	Migenix, Inc.	Compositions and methods for treating or preventing Hepadnaviridae infection
EA200700718A1 (ru) *	2004-10-06	2007-12-28	Мидженикс Инк.	Комбинированные противовирусные композиции, содержащие кастаноспермин, и способы их применения
JP2009545621A (ja) *	2006-08-02	2009-12-24	ユナイテッドセラピューティクスコーポレーション	ウィルス感染症のリポソーム処置
KR20100127842A (ko) *	2008-03-26	2010-12-06	유니버시티 오브 옥스퍼드	소포체 표적화 리포좀
US8703744B2 (en) *	2009-03-27	2014-04-22	The Chancellor, Masters And Scholars Of The University Of Oxford	Cholesterol level lowering liposomes
US11369592B2 (en)	2020-02-21	2022-06-28	Florida State University Research Foundation, Inc.	Treatment of human coronavirus infections using alpha-glucosidase glycoprotein processing inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3650377T2 (de) *	1985-12-23	1996-02-22	Hutchinson Fred Cancer Res	Regulierung der retroviralen replikation, infektion und pathogenese.
ZA883925B (en) *	1987-06-08	1989-02-22	Merrell Dow Pharma	Inhibitors of glycoprotein processing having anti-retroviral activity
CA1315276C (en) *	1987-07-02	1993-03-30	Paul S. Liu	Castanospermine esters and glycosides
US4952585A (en) *	1988-12-15	1990-08-28	Merrell Dow Pharmaceuticals Inc.	Castanospermine esters in the inhibition of tumor metastasis

1987
- 1987-09-29 US US07/102,070 patent/US5004746A/en not_active Expired - Lifetime
1988
- 1988-09-23 ZA ZA887160A patent/ZA887160B/xx unknown
- 1988-09-26 ES ES88115778T patent/ES2058201T3/es not_active Expired - Lifetime
- 1988-09-26 EP EP88115778A patent/EP0309952B1/en not_active Expired - Lifetime
- 1988-09-26 DE DE3850335T patent/DE3850335T2/de not_active Expired - Fee Related
- 1988-09-26 AU AU22802/88A patent/AU614993B2/en not_active Ceased
- 1988-09-26 AT AT88115778T patent/ATE107506T1/de not_active IP Right Cessation
- 1988-09-27 JP JP63239891A patent/JP2761898B2/ja not_active Expired - Fee Related
- 1988-09-28 IE IE293388A patent/IE64311B1/en not_active IP Right Cessation
- 1988-09-28 KR KR88012544A patent/KR960009416B1/ko not_active Expired - Fee Related
- 1988-09-28 DK DK198805388A patent/DK172788B1/da not_active IP Right Cessation
- 1988-09-29 PH PH37614A patent/PH24431A/en unknown

Also Published As

Publication number	Publication date
IE882933L (en)	1989-03-29
KR960009416B1 (en)	1996-07-19
JP2761898B2 (ja)	1998-06-04
DE3850335T2 (de)	1994-10-13
AU2280288A (en)	1989-04-06
EP0309952B1 (en)	1994-06-22
KR890004701A (ko)	1989-05-09
DK538888D0 (da)	1988-09-28
ZA887160B (en)	1989-05-30
US5004746A (en)	1991-04-02
DE3850335D1 (de)	1994-07-28
EP0309952A3 (en)	1990-09-26
DK172788B1 (da)	1999-07-19
ES2058201T3 (es)	1994-11-01
JPH01106821A (ja)	1989-04-24
ATE107506T1 (de)	1994-07-15
IE64311B1 (en)	1995-07-26
AU614993B2 (en)	1991-09-19
EP0309952A2 (en)	1989-04-05
PH24431A (en)	1990-06-25

Legal Events

Date	Code	Title	Description
2005-06-06	PBP	Patent lapsed	Country of ref document: DK

Publication	Publication Date	Title
DK538888A (da)	1989-03-30	Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat
FI952302L (fi)	1995-05-11	Pyran-2-onit ja 5,6-dihydropyranonit, jotka ovat käyttökelpoisia HIV:n ja muiden retrovirusten hoidossa
FI891716A7 (fi)	1989-10-13	HIV-proteaasi-inhibiittoreita, jotka ovat käyttökelpoisia AIDS'in hoidossa
FI942112L (fi)	1994-05-06	AIDS:n hoidossa käyttökelpoisia HIV-proteaasi-inhibiittoreita
DK0509019T3 (da)	1999-04-19	Behandling af humane retrovirale infektioner med 2',3'-dideoxyinosin
ES554967A0 (es)	1987-12-16	Un procedimiento para preparar una formulacion farmaceutica que contiene un 2'3'-didesoxi-nucleosido.
DK198791D0 (da)	1991-12-10	Terapeutiske kombinationer af 3'-azido-3'-desoxythymidin og andre terapeutiske midler
DK162965C (da)	1992-06-01	Anvendelse af et difluornucleosid eller et farmaceutisk acceptabelt salt deraf til fremstilling af et laegemiddel til behandling af neoplasma
SE8704298D0 (sv)	1987-11-03	Compounds for use in therapy
FI893962A7 (fi)	1990-02-25	HIV-proteaasi-inhibiittoreita, jotka ovat hyödyllisiä AIDS:in hoidossa
ES479474A1 (es)	1979-12-16	Procedimiento para la obtencion de una composicion a base dederivados de la piridina de accion cerebral.
DK1142891T3 (da)	2007-08-27	Salte og amider af (-)cis-5-fluor-2'-deoxy-thiacytidin der er egnede til behandling af hepatitis B
DK524788A (da)	1988-11-18	Anvendelse af morphin-antagonister til fremstilling af laegemidler med immunomodulerende og antiviral effekt, isaer til behandling af erhvervede immundefekt-tilstande
ATE100098T1 (de)	1994-01-15	Nukleoside, ihre herstellung und pharmazeutische zusammenstellungen.
DE3875769D1 (de)	1992-12-17	Therapeutische nukleoside.
DK708188D0 (da)	1988-12-20	5- og 6-leddede heterocycliske forbindelser og farmaceutisk acceptable saltderivater heraf til anvendelse ved behandling af aids
ATE126435T1 (de)	1995-09-15	Antiherpes-castanosperminester.
DK16389A (da)	1989-07-16	Anvendelse af en blanding til behandling af alopecia
DK707988A (da)	1989-06-22	Fremgangsmaade til at haemme virus
ES2037807T3 (es)	1993-07-01	Medicamentos que contienen en combinacion interferon y 1-desoxi-piperidinosas, procedimiento para su fabricacion y su aplicacion.
AU1792788A (en)	1988-12-06	Rubradirin derivatives for treatment of hiv infection
NO900616D0 (no)	1990-02-08	Fremgangsmaate for fraksjonering av avlinger i industrieltraamateriale.