DK544883A - Stabile plurilamellare vesikler - Google Patents

Stabile plurilamellare vesikler Download PDF

Info

Publication number: DK544883A
Authority: DK; Denmark
Prior art keywords: vesicles; aqueous phase; stable; dispersion; organic solvent
Prior art date: 1982-03-29

Application number

DK544883A

Other languages

English (en)

Other versions

DK163105B (da

DK163105C (da

DK544883D0 (da

Inventor

Robert Parker Lenk

Michael Wayne Fountain

Andrew Stuart Janoff

Marc Jeffrey Ostro

Micrea Constantine Popescu

Original Assignee

Liposome Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-03-29

Filing date

1983-11-28

Publication date

1983-11-28

1983-03-24 Priority claimed from US06/476,496 external-priority patent/US4522803A/en

1983-11-28 Application filed by Liposome Co Inc filed Critical Liposome Co Inc

1983-11-28 Publication of DK544883A publication Critical patent/DK544883A/da

1983-11-28 Publication of DK544883D0 publication Critical patent/DK544883D0/da

1992-01-20 Publication of DK163105B publication Critical patent/DK163105B/da

1992-06-15 Application granted granted Critical

1992-06-15 Publication of DK163105C publication Critical patent/DK163105C/da

Links

239000008346 aqueous phase Substances 0.000 abstract 3
239000012455 biphasic mixture Substances 0.000 abstract 2
239000006185 dispersion Substances 0.000 abstract 2
150000002632 lipids Chemical class 0.000 abstract 2
239000003960 organic solvent Substances 0.000 abstract 2
241000145525 Spinach latent virus Species 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000001804 emulsifying effect Effects 0.000 abstract 1
238000001704 evaporation Methods 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
-1 phosphatidyl choline Chemical class 0.000 abstract 1
WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK544883A 1982-03-29 1983-11-28 Fremgangsmaade til fremstilling af stabile plurilamellare vesikler DK163105C (da)

Applications Claiming Priority (14)

Application Number	Priority Date	Filing Date	Title
US36299482A	1982-03-29	1982-03-29
US36299582A	1982-03-29	1982-03-29
US36299482		1982-03-29
US36299582		1982-03-29
US41146682A	1982-08-25	1982-08-25
US41146682		1982-08-25
US44724782A	1982-12-06	1982-12-06
US44724782		1982-12-06
US46390083A	1983-02-04	1983-02-04
US46390083		1983-02-04
PCT/US1983/000419 WO1983003383A1 (en)	1982-03-29	1983-03-24	Stable plurilamellar vesicles
US8300419		1983-03-24
US06/476,496 US4522803A (en)	1983-02-04	1983-03-24	Stable plurilamellar vesicles, their preparation and use
US47649683		1983-03-24

Publications (4)

Publication Number	Publication Date
DK544883A true DK544883A (da)	1983-11-28
DK544883D0 DK544883D0 (da)	1983-11-28
DK163105B DK163105B (da)	1992-01-20
DK163105C DK163105C (da)	1992-06-15

Family

ID=27559847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK544883A DK163105C (da)	1982-03-29	1983-11-28	Fremgangsmaade til fremstilling af stabile plurilamellare vesikler

Country Status (14)

Country	Link
EP (1)	EP0092453B1 (da)
AU (1)	AU564876B2 (da)
DD (1)	DD210217A5 (da)
DE (1)	DE3373273D1 (da)
DK (1)	DK163105C (da)
FI (1)	FI83161C (da)
GR (1)	GR78163B (da)
HK (1)	HK96190A (da)
IE (1)	IE54706B1 (da)
IL (1)	IL68250A (da)
NZ (1)	NZ203746A (da)
PT (1)	PT76476B (da)
SG (1)	SG13489G (da)
WO (1)	WO1983003383A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5030453A (en) *	1983-03-24	1991-07-09	The Liposome Company, Inc.	Stable plurilamellar vesicles
DE3336583A1 (de) *	1983-09-26	1985-04-25	Udo Dr. 8400 Regensburg Ehrenfeld	Erzeugnis zur diagnose und therapie von malignen tumoren
DE3483949D1 (de) *	1983-09-26	1991-02-21	Udo Dr Med Ehrenfeld	Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr.
JPH0753661B2 (ja) *	1984-03-08	1995-06-07	フアレスフアーマスーチカルリサーチエヌブイ	プロ―リポソーム組成物及びリポソームの水性分散物を作る方法
CH668554A5 (de) *	1984-04-09	1989-01-13	Sandoz Ag	Liposomen welche polypeptide mit interleukin-2-aktivitaet enthalten sowie verfahren zu ihrer herstellung.
AU591466B2 (en) *	1984-10-22	1989-12-07	Vestar, Inc.	Method of delivering micellular particles encapsulating imaging and chemotherapeutic agents to tumors in a body
EP0179660A3 (en) *	1984-10-26	1987-08-12	The Liposome Company, Inc.	Multilayered vesicles prepared by reverse-phase evaporation
BE902199A (fr) *	1984-10-29	1985-07-31	Vira Tek Inc	Procede de traitement medical de maladies virales utilisant le 1-beta-d-ribofurannosyl-1, 2,4-triazole-3-carboxamide.
US5409704A (en) *	1985-06-26	1995-04-25	The Liposome Company, Inc.	Liposomes comprising aminoglycoside phosphates and methods of production and use
DE3689769T2 (de) *	1985-07-05	1994-07-21	Liposome Co Inc	Multilamellare liposome mit verbesserter einschliessungswirkung.
IL79114A (en) *	1985-08-07	1990-09-17	Allergan Pharma	Method and composition for making liposomes
US4983397A (en) *	1985-08-19	1991-01-08	Board Of Regents, University Of Texas System	Pharmaceutical compositions consisting of acylated phospholipids
US5068198A (en) *	1986-03-26	1991-11-26	Syntex (U.S.A.) Inc.	Liquid single reagent for assays involving confining gels
AU609387B2 (en) *	1986-03-26	1991-05-02	Syntex (U.S.A.) Inc.	Liquid single reagent for assays
JPH0751496B2 (ja) *	1986-04-02	1995-06-05	武田薬品工業株式会社	リポソ−ムの製造法
CA1320130C (en) *	1986-06-12	1993-07-13	Alan L. Weiner	Methods and compositions using liposome-encapsulated non-steroidal anti-inflammatory drugs
PT85537B (pt) *	1986-08-18	1990-06-29	Univ Texas	Processo para a preparacao de um sistema de administracao farmaceutica contendo peptidos apresentando quimiotaxia
MX9203808A (es) *	1987-03-05	1992-07-01	Liposome Co Inc	Formulaciones de alto contenido de medicamento: lipido, de agentes liposomicos-antineoplasticos.
US4914088A (en) *	1987-04-02	1990-04-03	Thomas Glonek	Dry eye treatment solution and method
FR2648462B1 (fr) *	1989-06-15	1994-01-28	Oreal	Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede
SK7092003A3 (en)	2000-11-09	2004-06-08	Neopharm Inc	SN-38 lipid complexes and methods of use
WO2003030864A1 (en)	2001-05-29	2003-04-17	Neopharm, Inc.	Liposomal formulation of irinotecan
DE102008005673A1 (de) *	2008-01-23	2009-08-20	Universität Augsburg	Bläschen, sowie Verfahren zur Herstellung und Manipulation von Bläschen
WO2016123365A1 (en)	2015-01-30	2016-08-04	The Regents Of The University Of Michigan	Liposomal particles comprising biological molecules and uses thereof
WO2016154544A1 (en)	2015-03-25	2016-09-29	The Regents Of The University Of Michigan	Compositions and methods for delivery of biomacromolecule agents
WO2017127503A2 (en) *	2016-01-19	2017-07-27	The Regents Of The University Of Michigan	Vesicle-encapsulated socs
US12257352B2 (en)	2016-06-20	2025-03-25	The Regents Of The University Of Michigan	Compositions and methods for delivery of biomacromolecule agents
CA3120453A1 (en)	2018-12-10	2020-06-18	EternaTear, Inc.	Ophthalmic formulations providing durable ocular lubrication

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4115544A (en) *	1976-08-18	1978-09-19	Alza Corporation	Ocular system made of bioerodible esters having linear ether
CH624011A5 (da) *	1977-08-05	1981-07-15	Battelle Memorial Institute
US4235871A (en) *	1978-02-24	1980-11-25	Papahadjopoulos Demetrios P	Method of encapsulating biologically active materials in lipid vesicles

1983
- 1983-03-24 WO PCT/US1983/000419 patent/WO1983003383A1/en not_active Ceased
- 1983-03-24 AU AU15196/83A patent/AU564876B2/en not_active Expired
- 1983-03-28 IL IL68250A patent/IL68250A/xx not_active IP Right Cessation
- 1983-03-28 GR GR70918A patent/GR78163B/el unknown
- 1983-03-28 IE IE690/83A patent/IE54706B1/en not_active IP Right Cessation
- 1983-03-29 PT PT76476A patent/PT76476B/pt unknown
- 1983-03-29 NZ NZ203746A patent/NZ203746A/en unknown
- 1983-03-29 DD DD83249304A patent/DD210217A5/de unknown
- 1983-03-29 EP EP83400652A patent/EP0092453B1/en not_active Expired
- 1983-03-29 DE DE8383400652T patent/DE3373273D1/de not_active Expired
- 1983-11-28 DK DK544883A patent/DK163105C/da not_active IP Right Cessation
- 1983-11-29 FI FI834364A patent/FI83161C/fi not_active IP Right Cessation
1989
- 1989-02-28 SG SG134/89A patent/SG13489G/en unknown
1990
- 1990-11-22 HK HK961/90A patent/HK96190A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IE54706B1 (en)	1990-01-17
IL68250A (en)	1990-02-09
NZ203746A (en)	1987-03-06
GR78163B (da)	1984-09-26
SG13489G (en)	1989-07-07
DE3373273D1 (de)	1987-10-08
HK96190A (en)	1990-11-30
DK163105B (da)	1992-01-20
FI83161C (fi)	1991-06-10
PT76476B (en)	1985-12-10
AU1519683A (en)	1983-10-24
DK163105C (da)	1992-06-15
EP0092453A2 (en)	1983-10-26
WO1983003383A1 (en)	1983-10-13
FI834364A7 (fi)	1983-11-29
IL68250A0 (en)	1983-06-15
EP0092453A3 (en)	1983-12-07
DK544883D0 (da)	1983-11-28
PT76476A (en)	1983-04-01
AU564876B2 (en)	1987-08-27
FI83161B (fi)	1991-02-28
DD210217A5 (de)	1984-06-06
FI834364A0 (fi)	1983-11-29
IE830690L (en)	1983-09-29
EP0092453B1 (en)	1987-09-02

Legal Events

Date	Code	Title	Description
2003-04-14	PUP	Patent expired

Publication	Publication Date	Title
DK544883A (da)	1983-11-28	Stabile plurilamellare vesikler
PL342473A1 (en)	2001-06-04	Method of obtaining a mixture of lipides and suspension of phopholipides containing such mixture
EP0322786A3 (en)	1990-05-02	Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons
ES2107668T3 (es)	1997-12-01	Liposomas, procedimiento para su preparacion y su uso en la elaboracion de un medicamento.
IE780464L (en)	1978-11-10	Liposome compositions
CA2227761A1 (en)	1997-02-13	Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizers
GB2249956B (en)	1994-07-13	Transdermal device with dual solvent for active ingredient
IE811298L (en)	1981-12-13	Magnetically-localizable biodegradable lipid microspheres
GB2136762B (en)	1986-09-03	Process for preparing lipid vesicles by vaporisation of solvents
ES542483A0 (es)	1986-05-16	Procedimiento de preparacion de una forma galenica para ad- ministracion por via oral
ES8606322A1 (es)	1986-04-16	Procedimiento para preparar derivados de benzodifuranona
ATE17318T1 (de)	1986-01-15	Verfahren zur lagerung von unilamellaren phospholipid-vesikeln.
NO913816D0 (no)	1991-09-27	Fremstilling av liposom- og lipidkompleksblandinger.
ATE16598T1 (de)	1985-12-15	Verfahren zur herstellung von sulfonierten arylphosphinen.
NO903733L (no)	1991-02-27	Fremgangsmaate for fjerning av kolesterol eller kolesterolestere fra eggeplomme.
BR9808641B1 (pt)	2009-05-05	processo para preparação de uma forma de dosagem sólida, oral de rápida desintegração de uma substáncia farmaceuticamente ativa que possui um sabor inaceitável.
KR880001284A (ko)	1988-04-22	단일 이중층 리포좀의 제조방법
KR890700021A (ko)	1989-03-02	인지질 조성물
ES2062701T3 (es)	1994-12-16	Procedimiento para refino de mezclas procedentes de tratamientos de medios grasos con ayuda de ciclodextrina y comprendiendo complejos de ciclodextrina esencialmente con substancias lipofilicas distintas de los acidos grasos.
DE3878922D1 (de)	1993-04-08	Mehrstufen-einkapselungs/ladeverfahren zur herstellung von lipophile heilmittel enthaltenden liposomen.
ES2093701T3 (es)	1997-01-01	Procedimiento para la preparacion de suspensiones acuosas de liposomas que contienen sustancias activas.
ZA884513B (en)	1989-03-29	Drug emulsion
ES525335A0 (es)	1984-11-01	Procedimiento para preparar esteres de acidos benzosulfonicos substituidos.
ATE65777T1 (de)	1991-08-15	Verfahren zur herstellung von peressigsaeure.
AU2030595A (en)	1996-01-04	Incorporation of a water-soluble active principle in a lipid