DK573783D0 - Gen,dna eller en underenhed heraf,som koder for human h2-preprorelaxin eller en underenhed deraf,fremgangsmaade til fremstilling af samme samt fremgangsmaade til fremstilling af human h2-preprorelaxin eller en underenhed deraf - Google Patents

Gen,dna eller en underenhed heraf,som koder for human h2-preprorelaxin eller en underenhed deraf,fremgangsmaade til fremstilling af samme samt fremgangsmaade til fremstilling af human h2-preprorelaxin eller en underenhed deraf

Info

Publication number
DK573783D0
DK573783D0 DK5737/83A DK573783A DK573783D0 DK 573783 D0 DK573783 D0 DK 573783D0 DK 5737/83 A DK5737/83 A DK 5737/83A DK 573783 A DK573783 A DK 573783A DK 573783 D0 DK573783 D0 DK 573783D0
Authority
DK
Denmark
Prior art keywords
preprorelaxin
substance
procedure
human
genes
Prior art date
Application number
DK5737/83A
Other languages
English (en)
Other versions
DK171684B1 (da
DK573783A (da
Inventor
Peter John Hudson
Hugh David Niall
Geoffrey William Tregear
Original Assignee
Florey Howard Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3769889&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK573783(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Florey Howard Inst filed Critical Florey Howard Inst
Publication of DK573783D0 publication Critical patent/DK573783D0/da
Publication of DK573783A publication Critical patent/DK573783A/da
Application granted granted Critical
Publication of DK171684B1 publication Critical patent/DK171684B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK573783A 1982-12-13 1983-12-13 Dobbeltstrenget DNA-fragment, der koder for human-H2-præprorelaxin, human-H2-prorelaxin eller A- og B-kæderne i human-H2-relaxin, samt DNA-transfervektor, der indeholder en cDNA-deoxynukleotidsekvens, som svarer til et sådant DNA-fragment, celle transformeret med en sådan DNA-transfervektor, og fremgangsmåde til fremstilling af human-H2-prorelaxin eller -H2-relaxin ved dyrkning af en sådan celle DK171684B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPF724782 1982-12-13
AUPF724782 1982-12-13

Publications (3)

Publication Number Publication Date
DK573783D0 true DK573783D0 (da) 1983-12-13
DK573783A DK573783A (da) 1984-06-14
DK171684B1 DK171684B1 (da) 1997-03-10

Family

ID=3769889

Family Applications (2)

Application Number Title Priority Date Filing Date
DK573783A DK171684B1 (da) 1982-12-13 1983-12-13 Dobbeltstrenget DNA-fragment, der koder for human-H2-præprorelaxin, human-H2-prorelaxin eller A- og B-kæderne i human-H2-relaxin, samt DNA-transfervektor, der indeholder en cDNA-deoxynukleotidsekvens, som svarer til et sådant DNA-fragment, celle transformeret med en sådan DNA-transfervektor, og fremgangsmåde til fremstilling af human-H2-prorelaxin eller -H2-relaxin ved dyrkning af en sådan celle
DK143492A DK172012B1 (da) 1982-12-13 1992-11-30 Rekombinant human-H2-præprorelaxin, -prorelaxin og -relaxin samt polypeptid med relaxinaktivitet.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK143492A DK172012B1 (da) 1982-12-13 1992-11-30 Rekombinant human-H2-præprorelaxin, -prorelaxin og -relaxin samt polypeptid med relaxinaktivitet.

Country Status (14)

Country Link
US (1) US4758516A (da)
EP (2) EP0303033B1 (da)
JP (3) JP2545055B2 (da)
KR (1) KR940002536B1 (da)
AT (2) ATE90360T1 (da)
CA (1) CA1220735A (da)
DE (1) DE3382249D1 (da)
DK (2) DK171684B1 (da)
ES (6) ES527964A0 (da)
HU (1) HU197767B (da)
IE (1) IE63902B1 (da)
IL (1) IL70414A (da)
NZ (1) NZ206534A (da)
ZA (1) ZA839231B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69469A (en) * 1982-08-12 1991-06-10 Florey Howard Inst Polypeptide having human h1-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors
US5179195A (en) * 1982-12-13 1993-01-12 Howard Florey Institute Of Experimental Physiology And Medicine Human relaxin polypeptides
US4835251A (en) * 1986-06-23 1989-05-30 Genetech, Inc. Method of chain combination
AU612594B2 (en) * 1986-09-12 1991-07-18 Genentech Inc. Human prorelaxin
JP2815649B2 (ja) * 1988-02-26 1998-10-27 ジェネンテク，インコーポレイテッド ヒトレラキシン製剤
DE69001248T2 (de) * 1989-05-04 1993-10-14 Genentech Inc Verfahren und zusammensetzungen zur isolation von menschlichem relaxin.
US5089419A (en) * 1989-08-07 1992-02-18 International Canine Genetics Detection of pregnancy by identification of the c peptide of relaxin in the urine of animals
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy
US5478807A (en) * 1991-08-19 1995-12-26 Genentech, Inc. Use of relaxin in the treatment of bradycardia
JPH07508341A (ja) * 1991-10-28 1995-09-14 ボード・オヴ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム 生物サンプルおよび体液中の正常細胞と悪性腫瘍細胞とにおける分化マーカーの検出方法
US6348327B1 (en) 1991-12-06 2002-02-19 Genentech, Inc. Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
EP0707650B1 (en) * 1993-06-21 2003-05-21 Genentech, Inc. Process for producing human relaxin
US20050032683A1 (en) * 2000-10-04 2005-02-10 Amento Edward P. Methods of modulating apoptosis by administration of relaxin agonists or antagonists
US20040006205A1 (en) * 2001-04-03 2004-01-08 Li Li Therapeutic polypeptides, nucleic acids encoding same, and methods of use
AU2002324727A1 (en) * 2001-08-17 2003-03-03 The Board Of Trustees Of The Leland Stanford Junior University Mammalian relaxin receptors
AU2003903124A0 (en) * 2003-06-20 2003-07-10 Mark Del Borgo Analogues of heteromeric proteins
EP1753449A4 (en) 2004-04-30 2009-09-23 Corthera Inc METHOD AND COMPOSITIONS FOR CONTROLLING FEDERAL GROWTH BY RELAXIN MODULATION
US20060052304A1 (en) * 2004-09-02 2006-03-09 Bas Medical, Inc. Method for remodeling bone and related sutures
AU2009246116B2 (en) * 2008-05-16 2013-02-14 Corthera, Inc. Method of preventing premature delivery
GR1006941B (el) 2009-06-01 2010-08-27 Χημικα Και Βιοφαρμακευτικα Εργαστηρια Πατρων Αε (Cbl-Patras), Πεπτιδικη συνθεση (peptide synthesis)
US8389475B2 (en) * 2009-08-10 2013-03-05 The Board Of Trustees Of The Leland Stanford Junior University Relaxin analogs
SMT201900495T1 (it) 2010-08-17 2019-11-13 Ambrx Inc Polipeptidi di relaxina modificati e loro usi
US9382305B2 (en) 2011-07-01 2016-07-05 Bayer Intellectual Property Gmbh Relaxin fusion polypeptides and uses thereof
EP2630964A1 (en) 2012-02-22 2013-08-28 Immundiagnostik AG Method and medicament for treating patients in risk of prediabetes and type-2 diabetes
WO2015073727A1 (en) 2013-11-13 2015-05-21 Aequus Biopharma, Inc. Engineered glycoproteins and uses thereof
EP2946788A1 (en) 2014-05-23 2015-11-25 Immundiagnostik AG Method and composition for treating heart failure with preserved ejection fraction
JP7088911B2 (ja) 2016-05-18 2022-06-21 モデルナティエックス インコーポレイテッド リラキシンをコードするポリヌクレオチド
US10266578B2 (en) 2017-02-08 2019-04-23 Bristol-Myers Squibb Company Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
GR70279B (da) * 1979-09-12 1982-09-03 Univ California
US4267101A (en) * 1980-02-01 1981-05-12 Serono Laboratories Inc. Process for obtaining human relaxin from fetal membranes
EP0068375A3 (en) * 1981-06-22 1983-04-13 G.D. Searle & Co. Recombinant dna techniques for the production of relaxin
IE55479B1 (en) * 1982-02-12 1990-09-26 Florey Howard Inst Molecular cloning and characterization of the gene sequence coding for porcine relaxin
IL69469A (en) * 1982-08-12 1991-06-10 Florey Howard Inst Polypeptide having human h1-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors

Also Published As

Publication number Publication date
ES557531A0 (es) 1988-02-16
ATE62507T1 (de) 1991-04-15
ES552093A0 (es) 1987-09-01
IL70414A0 (en) 1984-03-30
ES8708016A1 (es) 1987-09-01
IE832908L (en) 1984-06-13
JPH06100585A (ja) 1994-04-12
CA1220735A (en) 1987-04-21
DK171684B1 (da) 1997-03-10
DK172012B1 (da) 1997-09-15
DE3382249D1 (de) 1991-05-16
DK573783A (da) 1984-06-14
ZA839231B (en) 1984-08-29
EP0112149B1 (en) 1991-04-10
JP2677332B2 (ja) 1997-11-17
JP2891882B2 (ja) 1999-05-17
EP0303033A2 (en) 1989-02-15
ES8801675A1 (es) 1988-02-16
JP2545055B2 (ja) 1996-10-16
ES544293A0 (es) 1988-04-16
DK143492A (da) 1992-11-30
KR840007024A (ko) 1984-12-04
EP0303033A3 (en) 1989-10-25
ES8602133A1 (es) 1985-11-16
ES527964A0 (es) 1985-11-16
EP0112149A2 (en) 1984-06-27
NZ206534A (en) 1988-05-30
IL70414A (en) 1991-06-10
HU197767B (en) 1989-05-29
ES552095A0 (es) 1987-12-16
EP0112149A3 (en) 1985-05-22
ES552094A0 (es) 1987-09-01
EP0303033B1 (en) 1993-06-09
ES8708015A1 (es) 1987-09-01
JPH07173198A (ja) 1995-07-11
ES8801373A1 (es) 1987-12-16
IE63902B1 (en) 1995-06-14
KR940002536B1 (ko) 1994-03-25
ATE90360T1 (de) 1993-06-15
DK143492D0 (da) 1992-11-30
US4758516A (en) 1988-07-19
ES8802249A1 (es) 1988-04-16
JPS59156284A (ja) 1984-09-05

Similar Documents

Publication Publication Date Title
DK573783A (da) Gen, dna eller en underenhed heraf, som koder for human h2-preprorelaxin eller en underenhed deraf, fremgangsmaade til fremstilling af samme samt fremgangsmaade til fremstilling af human h2-preprorelaxin eller en underenhed deraf
DK366483D0 (da) Gen, dna-transfervektor eller underenhed heraf, der koder for human preprorelaxin eller en underenhed deraf, fremgangsmade til fremstilling af samme samt fremgangsmade til fremstilling af human preprorelaxin eller en underenhed deraf
DK478383A (da) Immunogent protein- eller peptidkompleks, fremgangsmaade til fremstilling deraf og anvendelse deraf som immunstimulerende middel og som vaccine
FI893517A7 (fi) Blad foer roterande graesklippningsmaskin eller liknande.
FI863096L (fi) Absorberande material, helst anvaendning i engaongsartiklar saosom bloejor, sanitetsbindor eller saorfoerband.
FI873645A0 (fi) Ligg- och/eller sittmoebel.
SE8501709L (sv) Forbettringar inom eller som henfor sig till interleukinterapi
FI861892A0 (fi) Faongapparat, till exempel foer hisskorg eller motvikt.
FI864702L (fi) Filterkropp, saerskilt en med teblad eller liknande aemne fylld filterpaose.
IT8619181A0 (it) Piattaforma di pala di turbina.
DK196687D0 (da) Kombineret vaccine, samt fremgangsmaade til fremstilling deraf
FI871080A0 (fi) 1,1-disubstituerade cyklopropanderivat, foerfarande foer deras framstaellning samt deras anvaendning som antimykotiska medel eller mellanprodukter.
NO155980C (no) Sikkerhetsbeholder, saerlig pengeskap eller hvelv.
DK348883D0 (da) Aryl(aryloxy eller arylthio)azolomethaner, deres fremstilling og anvendelse
FI860468A7 (fi) Foerfarande foer torkning av pulverformigt, kornigt, spaonformigt eller motsvarande material.
DK151788D0 (da) Hybridserpiner og dna, som koder derfor
FI870865A7 (fi) Manoevreringsanordning foer en kippdoerr eller en sektionsdoerr.
FI872681A0 (fi) Kemiskt sjaelvkopierande eller ensamkopierande papper.
FI875032A0 (fi) Inloppslaoda foer pappersmaskiner eller dylika.
FI861488A0 (fi) Vaexel saerskilt foer hissar, lyftkranar eller dylika.
FI883635A7 (fi) Lyftanordning eller s.k. lyftplattform som kan monteras pao fordon.
NO882225L (no) Vaksine, samt fremgangsmaate for fremstilling derav.
FI861035A0 (fi) Hammare eller liknande arbetsredskap.
FI875285A0 (fi) Stickad eller virkad strumpprodukt.
FI864542A0 (fi) Golvbrunn eller liknande.

Legal Events

Date Code Title Description
PUP Patent expired