DK64990A - Kunstigt gen, som koder for autentisk humant serumalbumin, fremgangsmaade til fremstilling deraf, rekombinant-dna-molekyle indeholdende genet, vaertsorganisme transformeret dermed, fremgangsmaade til fremstilling af autentisk humant serumalbumin og farmaceutisk praeparat indeholdende saaledes fremstillet serumalbumin - Google Patents

Kunstigt gen, som koder for autentisk humant serumalbumin, fremgangsmaade til fremstilling deraf, rekombinant-dna-molekyle indeholdende genet, vaertsorganisme transformeret dermed, fremgangsmaade til fremstilling af autentisk humant serumalbumin og farmaceutisk praeparat indeholdende saaledes fremstillet serumalbumin Download PDF

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Publication number
DK64990A
DK64990A DK064990A DK64990A DK64990A DK 64990 A DK64990 A DK 64990A DK 064990 A DK064990 A DK 064990A DK 64990 A DK64990 A DK 64990A DK 64990 A DK64990 A DK 64990A
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DK
Denmark
Prior art keywords
serum albumin
human serum
authentic human
recombinant dna
dna molecule
Prior art date
Application number
DK064990A
Other languages
English (en)
Other versions
DK163937B (da
DK163937C (da
DK64990D0 (da
Inventor
Bertil Aaberg
Andras Simoncsits
Miklos Kalman
Imre Cserpan
Gyoergy Bajszar
Original Assignee
Skandigen Ab
Mta Szegedi Biolog Koezponti
Vepex Contractor Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20369553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK64990(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Skandigen Ab, Mta Szegedi Biolog Koezponti, Vepex Contractor Ltd filed Critical Skandigen Ab
Publication of DK64990D0 publication Critical patent/DK64990D0/da
Publication of DK64990A publication Critical patent/DK64990A/da
Publication of DK163937B publication Critical patent/DK163937B/da
Application granted granted Critical
Publication of DK163937C publication Critical patent/DK163937C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK064990A 1987-09-14 1990-03-13 Strukturelt gen, som koder for autentisk humant serumalbumin til ekspression i en ikke-human vaert, fremgangsmaade til fremstilling deraf, rekombinant-dna-molekyle indeholdende genet, vaertsorganisme transformeret dermed og fremgangsmaade til fremstilling af autentisk humant serumalbumin DK163937C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8703539A SE459586B (sv) 1987-09-14 1987-09-14 Strukturgen som kodar foer autentiskt humant serum albumin och foerfarande foer dess framstaellning
PCT/SE1988/000470 WO1989002467A1 (en) 1987-09-14 1988-09-13 Artificial gene coding for authentic human serum albumin, use thereof, and method of producing the same

Publications (4)

Publication Number Publication Date
DK64990D0 DK64990D0 (da) 1990-03-13
DK64990A true DK64990A (da) 1990-05-14
DK163937B DK163937B (da) 1992-04-21
DK163937C DK163937C (da) 1992-09-14

Family

ID=20369553

Family Applications (1)

Application Number Title Priority Date Filing Date
DK064990A DK163937C (da) 1987-09-14 1990-03-13 Strukturelt gen, som koder for autentisk humant serumalbumin til ekspression i en ikke-human vaert, fremgangsmaade til fremstilling deraf, rekombinant-dna-molekyle indeholdende genet, vaertsorganisme transformeret dermed og fremgangsmaade til fremstilling af autentisk humant serumalbumin

Country Status (11)

Country Link
EP (1) EP0308381B1 (da)
JP (1) JP2865683B2 (da)
AT (1) ATE135740T1 (da)
CA (1) CA1340650C (da)
DD (1) DD282473A5 (da)
DE (1) DE3855122T2 (da)
DK (1) DK163937C (da)
IL (1) IL87748A (da)
PL (1) PL274669A1 (da)
SE (1) SE459586B (da)
WO (1) WO1989002467A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2791418B2 (ja) * 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体
FR2649991B2 (fr) * 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
US5759802A (en) * 1988-10-26 1998-06-02 Tonen Corporation Production of human serum alubumin A
US5225538A (en) * 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US6406697B1 (en) 1989-02-23 2002-06-18 Genentech, Inc. Hybrid immunoglobulins
US5116964A (en) * 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
ATE92107T1 (de) * 1989-04-29 1993-08-15 Delta Biotechnology Ltd N-terminale fragmente von menschliches serumalbumin enthaltenden fusionsproteinen.
GB8909916D0 (en) * 1989-04-29 1989-06-14 Delta Biotechnology Ltd Polypeptides
CA2017176A1 (en) * 1989-05-22 1990-11-22 Yoshitomi Pharmaceutical Industries Ltd. Albumin gene-containing plasmid, transformant carrying same, production of such transformant and production of albumin
JPH0669365B2 (ja) * 1989-05-22 1994-09-07 株式会社ミドリ十字 アルブミン遺伝子を含むプラスミド、形質転換体、形質転換体の製造方法、アルブミンの製造方法
NL8901932A (nl) * 1989-07-26 1991-02-18 Mogen Int Produktie van heterologe eiwitten in planten of plantecellen.
GB8923521D0 (en) * 1989-10-18 1989-12-06 Delta Biotechnology Ltd Yeast promoter
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
JPH07308199A (ja) * 1994-05-18 1995-11-28 Green Cross Corp:The ヒト血清アルブミンの製造方法
US5514551A (en) * 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
GB9526733D0 (en) 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
US6946134B1 (en) 2000-04-12 2005-09-20 Human Genome Sciences, Inc. Albumin fusion proteins
EP2213743A1 (en) 2000-04-12 2010-08-04 Human Genome Sciences, Inc. Albumin fusion proteins
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
AU2002364586A1 (en) 2001-12-21 2003-07-30 Delta Biotechnology Limited Albumin fusion proteins
WO2005003296A2 (en) 2003-01-22 2005-01-13 Human Genome Sciences, Inc. Albumin fusion proteins
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL66614A (en) * 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
EP0079739A3 (en) * 1981-11-12 1984-08-08 The Upjohn Company Albumin-based nucleotides, their replication and use, and plasmids for use therein
US6936694B1 (en) * 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
WO1986001515A1 (en) * 1984-08-29 1986-03-13 Chiron Corporation Expression of human connective tissue activator and related peptides
GB8427006D0 (en) * 1984-10-25 1984-11-28 Iq Bio Ltd Determination of chlamydia trachomatis
HU194308B (en) * 1984-11-23 1988-01-28 Mta Szbk Genetikai Intezete Process for preparing oligo- and polydeoxyribonucleotides
JPS6229985A (ja) * 1985-06-17 1987-02-07 ジエネツクス・コ−ポレ−シヨン クロ−ン化プレプロ−ヒト血清アルブミン遺伝子およびヒト血清アルブミン遺伝子、それらの遺伝子を含むプラスミド、プラスミドにより形質転換された微生物、およびその微生物を用いたプレプロ−ヒト血清アルブミン遺伝子の製造方法
US5451521A (en) * 1986-05-29 1995-09-19 Genetics Institute, Inc. Procoagulant proteins

Also Published As

Publication number Publication date
DK163937B (da) 1992-04-21
EP0308381A1 (en) 1989-03-22
WO1989002467A1 (en) 1989-03-23
IL87748A (en) 1993-06-10
JP2865683B2 (ja) 1999-03-08
DK163937C (da) 1992-09-14
DD282473A5 (de) 1990-09-12
JPH03501323A (ja) 1991-03-28
CA1340650C (en) 1999-07-13
DE3855122T2 (de) 1996-10-17
DK64990D0 (da) 1990-03-13
IL87748A0 (en) 1989-02-28
EP0308381B1 (en) 1996-03-20
SE459586B (sv) 1989-07-17
ATE135740T1 (de) 1996-04-15
SE8703539L (sv) 1989-03-15
SE8703539D0 (sv) 1987-09-14
DE3855122D1 (de) 1996-04-25
PL274669A1 (en) 1989-08-21

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