DK710488A - Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse - Google Patents

Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse

Info

Publication number: DK710488A
Authority: DK; Denmark
Prior art keywords: phenyl; lower alkyl; alkyl; alkoxy; heterocyclic
Prior art date: 1987-12-24

Application number

DK710488A

Other languages

Danish (da)

English (en)

Other versions

DK710488D0 (da

Inventor

Terence James Ward

Janet Christine White

Original Assignee

Wyeth John & Brother Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-24

Filing date

1988-12-20

Publication date

1989-06-25

1987-12-24 Priority claimed from GB878730193A external-priority patent/GB8730193D0/en

1988-08-19 Priority claimed from GB888819728A external-priority patent/GB8819728D0/en

1988-12-20 Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd

1988-12-20 Publication of DK710488D0 publication Critical patent/DK710488D0/da

1989-06-25 Publication of DK710488A publication Critical patent/DK710488A/da

Links

150000004657 carbamic acid derivatives Chemical class 0.000 title 1
210000002700 urine Anatomy 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 7
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 4
229910052736 halogen Inorganic materials 0.000 abstract 3
150000002367 halogens Chemical class 0.000 abstract 3
229910052760 oxygen Inorganic materials 0.000 abstract 3
229910052717 sulfur Inorganic materials 0.000 abstract 2
KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 1
150000001204 N-oxides Chemical class 0.000 abstract 1
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000004442 acylamino group Chemical group 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
239000004202 carbamide Substances 0.000 abstract 1
125000005518 carboxamido group Chemical group 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052727 yttrium Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Anesthesiology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK710488A 1987-12-24 1988-12-20 Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse DK710488A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878730193A GB8730193D0 (en)	1987-12-24	1987-12-24	Heterocyclic compounds
GB888819728A GB8819728D0 (en)	1988-08-19	1988-08-19	Heterocyclic compounds

Publications (2)

Publication Number	Publication Date
DK710488D0 DK710488D0 (da)	1988-12-20
DK710488A true DK710488A (da)	1989-06-25

Family

ID=26293248

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK710488A DK710488A (da)	1987-12-24	1988-12-20	Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse
DK082793A DK82793A (da)	1987-12-24	1993-07-08	Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK082793A DK82793A (da)	1987-12-24	1993-07-08	Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse

Country Status (18)

Country	Link
US (2)	US4983600A (de)
EP (2)	EP0323077B1 (de)
JP (1)	JP2588265B2 (de)
KR (1)	KR970009588B1 (de)
AT (2)	ATE67200T1 (de)
AU (1)	AU611976B2 (de)
CA (1)	CA1334095C (de)
DE (2)	DE3864807D1 (de)
DK (2)	DK710488A (de)
ES (2)	ES2051867T3 (de)
FI (1)	FI95031C (de)
GB (1)	GB2213816B (de)
GR (1)	GR3002701T3 (de)
HU (1)	HU204267B (de)
IE (2)	IE62231B1 (de)
IL (1)	IL88644A (de)
PH (1)	PH27437A (de)
PT (1)	PT89286B (de)

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EP0255297B1 (de) *	1986-07-31	1993-04-21	Beecham Group Plc	Azabicyclische Verbindungen, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung

1988
- 1988-12-08 IE IE366188A patent/IE62231B1/en not_active IP Right Cessation
- 1988-12-08 AU AU26702/88A patent/AU611976B2/en not_active Ceased
- 1988-12-08 IE IE102988A patent/IE63474B1/en not_active IP Right Cessation
- 1988-12-09 IL IL88644A patent/IL88644A/xx not_active IP Right Cessation
- 1988-12-09 CA CA000585519A patent/CA1334095C/en not_active Expired - Fee Related
- 1988-12-12 HU HU886399A patent/HU204267B/hu not_active IP Right Cessation
- 1988-12-14 EP EP88311802A patent/EP0323077B1/de not_active Expired - Lifetime
- 1988-12-14 ES ES88311802T patent/ES2051867T3/es not_active Expired - Lifetime
- 1988-12-14 EP EP89202801A patent/EP0361629B1/de not_active Expired - Lifetime
- 1988-12-14 AT AT88311802T patent/ATE67200T1/de not_active IP Right Cessation
- 1988-12-14 AT AT89202801T patent/ATE107304T1/de not_active IP Right Cessation
- 1988-12-14 ES ES89202801T patent/ES2053959T3/es not_active Expired - Lifetime
- 1988-12-14 DE DE8888311802T patent/DE3864807D1/de not_active Expired - Fee Related
- 1988-12-14 DE DE3850255T patent/DE3850255T2/de not_active Expired - Fee Related
- 1988-12-14 GB GB8829164A patent/GB2213816B/en not_active Expired - Fee Related
- 1988-12-20 DK DK710488A patent/DK710488A/da not_active Application Discontinuation
- 1988-12-21 PT PT89286A patent/PT89286B/pt not_active IP Right Cessation
- 1988-12-21 FI FI885917A patent/FI95031C/fi not_active IP Right Cessation
- 1988-12-22 KR KR1019880017218A patent/KR970009588B1/ko not_active Expired - Fee Related
- 1988-12-22 JP JP63324701A patent/JP2588265B2/ja not_active Expired - Fee Related
- 1988-12-23 PH PH37977A patent/PH27437A/en unknown
1989
- 1989-10-16 US US07/421,920 patent/US4983600A/en not_active Expired - Lifetime
- 1989-12-19 US US07/453,000 patent/US5106843A/en not_active Expired - Lifetime
1991
- 1991-09-12 GR GR91401252T patent/GR3002701T3/el unknown
1993
- 1993-07-08 DK DK082793A patent/DK82793A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
US5106843A (en)	1992-04-21
IE881029L (en)	1989-06-24
PH27437A (en)	1993-07-02
CA1334095C (en)	1995-01-24
ES2053959T3 (es)	1994-08-01
GR3002701T3 (en)	1993-01-25
GB2213816B (en)	1991-05-08
AU2670288A (en)	1989-06-29
ATE67200T1 (de)	1991-09-15
EP0361629A3 (en)	1990-06-13
EP0361629A2 (de)	1990-04-04
DE3864807D1 (de)	1991-10-17
IE883661L (en)	1989-05-24
IL88644A0 (en)	1989-07-31
EP0323077A1 (de)	1989-07-05
EP0323077B1 (de)	1991-09-11
PT89286B (pt)	1994-11-30
KR890009923A (ko)	1989-08-04
EP0361629B1 (de)	1994-06-15
IE63474B1 (en)	1995-04-19
KR970009588B1 (ko)	1997-06-14
AU611976B2 (en)	1991-06-27
ES2051867T3 (es)	1994-07-01
JPH01203365A (ja)	1989-08-16
DE3850255T2 (de)	1994-09-22
JP2588265B2 (ja)	1997-03-05
DK82793D0 (da)	1993-07-08
GB8829164D0 (en)	1989-01-25
IL88644A (en)	1993-05-13
DK710488D0 (da)	1988-12-20
FI885917A7 (fi)	1989-06-25
US4983600A (en)	1991-01-08
DK82793A (da)	1993-07-08
PT89286A (pt)	1989-12-29
FI95031C (fi)	1995-12-11
HUT53101A (en)	1990-09-28
ATE107304T1 (de)	1994-07-15
GB2213816A (en)	1989-08-23
IE62231B1 (en)	1995-01-11
FI95031B (fi)	1995-08-31
DE3850255D1 (de)	1994-07-21
HU204267B (en)	1991-12-30

Legal Events

Date	Code	Title	Description
2002-09-02	AHS	Application shelved for other reasons than non-payment

Publication	Publication Date	Title
DK710488D0 (da)	1988-12-20	Heterocycliske urinstof- eller carbamidsyrederivater, deres fremstilling og anvendelse
WO2000047580A3 (en)	2000-12-21	Phenyl urea and phenyl thiourea derivatives
EA200200446A1 (ru)	2002-12-26	НОВЫЕ α-АМИНОКИСЛОТНЫЕ СОЕДИНЕНИЯ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, ИХ СОДЕРЖАЩИЕ
ES2081563T3 (es)	1996-03-16	Benzamidas.
UY23364A1 (es)	1992-06-16	Nuevas sulfonilureas
FI872091A0 (fi)	1987-05-12	Kinolinkarboxylsyraderivat och deras framstaellning.
DK394189A (da)	1990-02-13	Arylalkylaminer og -amider med antikonvulsive og neurobeskyttende egenskaber
ATE155127T1 (de)	1997-07-15	Benzamid-derivate
DK189988D0 (da)	1988-04-07	Pyridylalkansyreforbindelser med aktivitet som thromboxan a2-antagonister
EP0341081A3 (en)	1990-12-27	Novel amino acid derivatives
DK233788A (da)	1988-11-02	Herbicid
ES8303305A1 (es)	1983-02-01	"un procedimiento para preparar derivados de urea y tiourea".
FR2224447A1 (en)	1974-10-31	N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics
ES8707500A1 (es)	1987-08-16	Procedimiento para la obtencion de isocianatos piperidinicos.
ES8800930A1 (es)	1987-12-01	Un metodo de preparacion de un compuesto de oxodiazina
FR2355498A1 (fr)	1978-01-20	Composes 1,3-diazacycliques substitues en position 2, leur preparation et leurs utilisations therapeutiques
FR2187323A1 (en)	1974-01-18	N-(substd alkyl)-2-alk(enyl)oxybenzamides - antiemetics digestion-regulators and psychotropics
ES2007750A6 (es)	1989-07-01	Procedimiento de obtencion de nuevos derivados de 4'- hodroxibencilamina.