DK74185A - 3-phenyl-2-propen-amin-derivater, fremgangsmaade til deres fremstilling og laegemidler indeholdende disse forbindelser - Google Patents

3-phenyl-2-propen-amin-derivater, fremgangsmaade til deres fremstilling og laegemidler indeholdende disse forbindelser Download PDF

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Publication number
DK74185A
DK74185A DK74185A DK74185A DK74185A DK 74185 A DK74185 A DK 74185A DK 74185 A DK74185 A DK 74185A DK 74185 A DK74185 A DK 74185A DK 74185 A DK74185 A DK 74185A
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DK
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Prior art keywords
alkyl
compounds
alkyloxy
dialkylamino
alkylamino
Prior art date
Application number
DK74185A
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English (en)
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DK74185D0 (da
Inventor
Jean-Claude Barriere
Jean-Pierre Corbet
Claude Cotrel
Daniel Farge
Jean-Marc Paris
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of DK74185D0 publication Critical patent/DK74185D0/da
Publication of DK74185A publication Critical patent/DK74185A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/20—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
    • C07C211/21—Monoamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK74185A 1984-02-16 1985-02-15 3-phenyl-2-propen-amin-derivater, fremgangsmaade til deres fremstilling og laegemidler indeholdende disse forbindelser DK74185A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8402338A FR2559765B1 (fr) 1984-02-16 1984-02-16 Nouveaux derives de la phenyl-3 propene-2 amine, leur preparation et les medicaments qui les contiennent

Publications (2)

Publication Number Publication Date
DK74185D0 DK74185D0 (da) 1985-02-15
DK74185A true DK74185A (da) 1985-08-17

Family

ID=9301090

Family Applications (1)

Application Number Title Priority Date Filing Date
DK74185A DK74185A (da) 1984-02-16 1985-02-15 3-phenyl-2-propen-amin-derivater, fremgangsmaade til deres fremstilling og laegemidler indeholdende disse forbindelser

Country Status (20)

Country Link
US (2) US4686309A (da)
EP (1) EP0153890B1 (da)
JP (1) JPS60208948A (da)
KR (1) KR850006934A (da)
AT (1) ATE39682T1 (da)
AU (1) AU576347B2 (da)
CA (1) CA1250298A (da)
CS (1) CS252826B2 (da)
DD (6) DD243491A5 (da)
DE (1) DE3567201D1 (da)
DK (1) DK74185A (da)
ES (6) ES540471A0 (da)
FR (1) FR2559765B1 (da)
GR (1) GR850388B (da)
HU (1) HUT41714A (da)
IL (1) IL74324A (da)
MA (1) MA20349A1 (da)
PT (1) PT79975B (da)
SU (2) SU1402251A3 (da)
ZA (1) ZA851127B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826844A (en) * 1987-09-30 1989-05-02 American Home Products Corporation Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols
US4745191A (en) * 1987-09-30 1988-05-17 American Home Products Corporation 1-((A-substituted phenyl-ω-substituted piperazinyl)alkenyl) cyclohexanol
US4996235A (en) * 1987-11-25 1991-02-26 Eli Lilly And Company 3,4-diphenylbutanamines
US4902710A (en) * 1988-12-14 1990-02-20 Eli Lilly And Company Serotonin and norepinephrine uptake inhibitors
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE10048714A1 (de) * 2000-09-30 2002-04-11 Gruenenthal Gmbh 5-Amino-1-penlen-3-ol-Derivate
US20050176136A1 (en) * 2003-11-19 2005-08-11 Dexcom, Inc. Afinity domain for analyte sensor
CN103819400B (zh) * 2013-09-16 2016-05-04 江西师范大学 一种多组分反应合成具有不对称结构1.4-二氢吡啶及其衍生物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3978129A (en) * 1972-01-28 1976-08-31 A. H. Robins Company, Incorporated Alkenyl- and alkanylamines
US4056630A (en) * 1973-02-24 1977-11-01 Beecham Group Limited Diphenylpropylamines for treating depression
US4018895A (en) * 1974-01-10 1977-04-19 Eli Lilly And Company Aryloxyphenylpropylamines in treating depression
US4018845A (en) * 1975-06-06 1977-04-19 Uop Inc. Hydrocarbon isomerization process
JPS5896045A (ja) * 1981-11-30 1983-06-07 Sumitomo Chem Co Ltd 新規なジフエニルアルカノアミン誘導体およびその製造法

Also Published As

Publication number Publication date
SU1402251A3 (ru) 1988-06-07
ES8604519A1 (es) 1986-02-01
ES545311A0 (es) 1986-02-01
ES8604485A1 (es) 1986-02-01
US4686309A (en) 1987-08-11
ES8700224A1 (es) 1986-10-16
DD239403A5 (de) 1986-09-24
FR2559765B1 (fr) 1986-06-13
ATE39682T1 (de) 1989-01-15
MA20349A1 (fr) 1985-10-01
DD243022A5 (de) 1987-02-18
AU3872685A (en) 1985-08-22
PT79975B (fr) 1987-09-14
EP0153890A2 (fr) 1985-09-04
DD243024A5 (de) 1987-02-18
ES8602605A1 (es) 1985-12-01
EP0153890A3 (en) 1986-08-27
IL74324A (en) 1988-03-31
SU1391495A3 (ru) 1988-04-23
DE3567201D1 (en) 1989-02-09
JPS60208948A (ja) 1985-10-21
KR850006934A (ko) 1985-10-25
ES545314A0 (es) 1986-02-01
DD243491A5 (de) 1987-03-04
US4755599A (en) 1988-07-05
ES545313A0 (es) 1986-02-01
DD243277A5 (de) 1987-02-25
HUT41714A (en) 1987-05-28
ES8604484A1 (es) 1986-02-01
CS252826B2 (en) 1987-10-15
GR850388B (da) 1985-06-07
ES8604486A1 (es) 1986-02-01
DD243494A5 (de) 1987-03-04
EP0153890B1 (fr) 1989-01-04
FR2559765A1 (fr) 1985-08-23
IL74324A0 (en) 1985-05-31
ES540471A0 (es) 1985-12-01
ES545312A0 (es) 1986-02-01
AU576347B2 (en) 1988-08-25
ES545310A0 (es) 1986-10-16
ZA851127B (en) 1985-09-25
CS108985A2 (en) 1987-03-12
DK74185D0 (da) 1985-02-15
PT79975A (fr) 1985-03-01
CA1250298A (fr) 1989-02-21

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