DOP2016000198A - Formulaciones tópicas de heparina - Google Patents

Formulaciones tópicas de heparina

Info

Publication number
DOP2016000198A
DOP2016000198A DO2016000198A DO2016000198A DOP2016000198A DO P2016000198 A DOP2016000198 A DO P2016000198A DO 2016000198 A DO2016000198 A DO 2016000198A DO 2016000198 A DO2016000198 A DO 2016000198A DO P2016000198 A DOP2016000198 A DO P2016000198A
Authority
DO
Dominican Republic
Prior art keywords
topical formulations
present
heparine
formulations
topical
Prior art date
Application number
DO2016000198A
Other languages
English (en)
Inventor
K R Patel
Prakash J Shah
M R Patel
A K Patel
Original Assignee
Troikaa Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52684592&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2016000198(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Troikaa Pharmaceuticals Ltd filed Critical Troikaa Pharmaceuticals Ltd
Publication of DOP2016000198A publication Critical patent/DOP2016000198A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se relaciona con formulaciones tópicas avanzadas de sales farmacéuticamente aceptables de Heparina que proporcionan penetración transdérmica mejorada. La presente invención proporciona formulaciones líquidas, no pegajosas, claras en las que el fármaco está listo para absorción y que son adecuadas para administración en la forma de una solución o una pulverización. Las formulaciones tópicas de la presente invención no forman película con escamas o similar a gel sobre la superficie de la piel luego de aplicación tópica.
DO2016000198A 2014-02-10 2016-08-03 Formulaciones tópicas de heparina DOP2016000198A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN475MU2014 2014-02-10

Publications (1)

Publication Number Publication Date
DOP2016000198A true DOP2016000198A (es) 2016-10-31

Family

ID=52684592

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2016000198A DOP2016000198A (es) 2014-02-10 2016-08-03 Formulaciones tópicas de heparina

Country Status (25)

Country Link
US (1) US9861655B2 (es)
EP (1) EP3104839B1 (es)
JP (1) JP6275877B2 (es)
KR (1) KR101822133B1 (es)
CN (1) CN106163498A (es)
AP (1) AP2016009350A0 (es)
AR (1) AR099333A1 (es)
AU (1) AU2015213569B2 (es)
CA (1) CA2938388C (es)
CL (1) CL2016001952A1 (es)
CU (1) CU24444B1 (es)
DK (1) DK3104839T3 (es)
DO (1) DOP2016000198A (es)
EA (1) EA032200B1 (es)
EC (1) ECSP16069947A (es)
IL (1) IL246974B (es)
MA (1) MA39304B1 (es)
MX (1) MX357765B (es)
MY (1) MY182620A (es)
NZ (1) NZ722830A (es)
PE (1) PE20161173A1 (es)
PH (1) PH12016501500A1 (es)
TW (1) TWI538697B (es)
UA (1) UA118279C2 (es)
WO (1) WO2015118512A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5927506B2 (ja) * 2010-04-13 2016-06-01 レルマダ セラピューティクス、インク． １−メチル−２’，６’−ピペコロキシリダイドの皮膚医薬組成物および使用方法
CN112546061B (zh) * 2021-02-25 2021-06-11 中南大学湘雅医院 一种肝素类药物组合物、喷鼻剂及其制备方法及应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3323389A1 (de) * 1983-06-29 1985-01-10 B. Braun Melsungen Ag, 3508 Melsungen Auf schleimhaeute des mundes, der nase und/oder des rachens wirkende arzneimittel auf der basis von heparin und tensiden
JPH02207018A (ja) * 1989-02-07 1990-08-16 Kao Corp 皮膚外用剤
ATE223202T1 (de) 1994-09-30 2002-09-15 Mika Pharma Ges Fuer Die Entwi Pharmazeutische zusammensetzung
IT1275955B1 (it) 1995-03-22 1997-10-24 Dompe Spa Formulazioni farmaceutiche in forma di gel tissotropico
JPH10279466A (ja) * 1997-04-07 1998-10-20 Kose Corp 外用剤
US6761903B2 (en) 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
BRPI0101486B1 (pt) 2001-04-17 2017-09-19 Cristália Produtos Químicos Farmacêuticos Ltda. Pharmaceutical composition for topic use containing heparin for the treatment of skin or mucosal injuries caused by burns
WO2008058333A1 (en) * 2006-11-15 2008-05-22 Arthritis Relief Plus Ltd Topical formulation and uses thereof
IT1400232B1 (it) * 2010-05-07 2013-05-24 Advance Holdings Ltd Composizione farmaceutica topica comprendente eparina
US9056137B2 (en) * 2011-04-01 2015-06-16 University Of Florida Research Foundation, Incorporated Thermo-sensitive, mucoadhesive or dermoadhesive, and penetration-enhancing formulations for topical delivery of therapeutics

Also Published As

Publication number Publication date
IL246974B (en) 2018-07-31
EA032200B1 (ru) 2019-04-30
PE20161173A1 (es) 2016-10-27
DK3104839T3 (da) 2020-01-20
EA201691596A1 (ru) 2017-01-30
AR099333A1 (es) 2016-07-13
AU2015213569A1 (en) 2016-08-18
CU20160119A7 (es) 2016-10-28
CA2938388A1 (en) 2015-08-13
ECSP16069947A (es) 2018-06-30
CU24444B1 (es) 2019-10-04
PH12016501500B1 (en) 2017-02-06
TWI538697B (zh) 2016-06-21
NZ722830A (en) 2018-01-26
US20170165291A1 (en) 2017-06-15
CL2016001952A1 (es) 2017-03-10
MA39304B1 (fr) 2018-12-31
AP2016009350A0 (en) 2016-07-31
MX2016010399A (es) 2017-02-23
JP6275877B2 (ja) 2018-02-07
JP2017505344A (ja) 2017-02-16
EP3104839B1 (en) 2019-11-13
EP3104839A1 (en) 2016-12-21
AU2015213569B2 (en) 2018-01-04
US9861655B2 (en) 2018-01-09
KR101822133B1 (ko) 2018-01-25
MA39304A1 (fr) 2018-01-31
MY182620A (en) 2021-01-27
TW201532631A (zh) 2015-09-01
CN106163498A (zh) 2016-11-23
MX357765B (es) 2018-07-23
CA2938388C (en) 2018-07-17
KR20160117529A (ko) 2016-10-10
PH12016501500A1 (en) 2017-02-06
UA118279C2 (uk) 2018-12-26
WO2015118512A1 (en) 2015-08-13

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