MA39304B1 - Formulations topiques d'héparine - Google Patents
Formulations topiques d'héparineInfo
- Publication number
- MA39304B1 MA39304B1 MA39304A MA39304A MA39304B1 MA 39304 B1 MA39304 B1 MA 39304B1 MA 39304 A MA39304 A MA 39304A MA 39304 A MA39304 A MA 39304A MA 39304 B1 MA39304 B1 MA 39304B1
- Authority
- MA
- Morocco
- Prior art keywords
- heparin
- topical formulations
- present
- relates
- formulations
- Prior art date
Links
- 239000012049 topical pharmaceutical composition Substances 0.000 title abstract 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002897 heparin Drugs 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000012669 liquid formulation Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention se rapporte à des formulations topiques avancées de sels pharmaceutiquement acceptables d'héparine fournissant une meilleure pénétration transdermique. La présente invention concerne des formulations transparentes, non collantes liquides dans lesquelles le médicament est prêt pour l'absorption et qui sont appropriées pour l'administration sous la forme d'une solution ou d'une pulvérisation. Les formulations topiques de la présente invention ne forment pas de film de type feuilleté ou en gel sur la surface de la peau lors d'une application topique.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN475MU2014 | 2014-02-10 | ||
| PCT/IB2015/050986 WO2015118512A1 (fr) | 2014-02-10 | 2015-02-10 | Formulations topiques d'héparine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA39304A1 MA39304A1 (fr) | 2018-01-31 |
| MA39304B1 true MA39304B1 (fr) | 2018-12-31 |
Family
ID=52684592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA39304A MA39304B1 (fr) | 2014-02-10 | 2015-02-10 | Formulations topiques d'héparine |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9861655B2 (fr) |
| EP (1) | EP3104839B1 (fr) |
| JP (1) | JP6275877B2 (fr) |
| KR (1) | KR101822133B1 (fr) |
| CN (1) | CN106163498A (fr) |
| AP (1) | AP2016009350A0 (fr) |
| AR (1) | AR099333A1 (fr) |
| AU (1) | AU2015213569B2 (fr) |
| CA (1) | CA2938388C (fr) |
| CL (1) | CL2016001952A1 (fr) |
| CU (1) | CU24444B1 (fr) |
| DK (1) | DK3104839T3 (fr) |
| DO (1) | DOP2016000198A (fr) |
| EA (1) | EA032200B1 (fr) |
| EC (1) | ECSP16069947A (fr) |
| IL (1) | IL246974B (fr) |
| MA (1) | MA39304B1 (fr) |
| MX (1) | MX357765B (fr) |
| MY (1) | MY182620A (fr) |
| NZ (1) | NZ722830A (fr) |
| PE (1) | PE20161173A1 (fr) |
| PH (1) | PH12016501500B1 (fr) |
| TW (1) | TWI538697B (fr) |
| UA (1) | UA118279C2 (fr) |
| WO (1) | WO2015118512A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150036825A (ko) * | 2010-04-13 | 2015-04-07 | 나지브 바불 | 1-메틸-2''-6''-피페콜옥실리디드의 피부 약제학적 조성물 및 사용 방법 |
| CN112546061B (zh) * | 2021-02-25 | 2021-06-11 | 中南大学湘雅医院 | 一种肝素类药物组合物、喷鼻剂及其制备方法及应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3323389A1 (de) * | 1983-06-29 | 1985-01-10 | B. Braun Melsungen Ag, 3508 Melsungen | Auf schleimhaeute des mundes, der nase und/oder des rachens wirkende arzneimittel auf der basis von heparin und tensiden |
| JPH02207018A (ja) * | 1989-02-07 | 1990-08-16 | Kao Corp | 皮膚外用剤 |
| DE19536244A1 (de) | 1994-09-30 | 1996-04-04 | Juergen Dr Regenold | Pharmazeutische Zusammensetzung zur lokalen Applikation |
| IT1275955B1 (it) | 1995-03-22 | 1997-10-24 | Dompe Spa | Formulazioni farmaceutiche in forma di gel tissotropico |
| JPH10279466A (ja) * | 1997-04-07 | 1998-10-20 | Kose Corp | 外用剤 |
| US6761903B2 (en) | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
| BRPI0101486B1 (pt) | 2001-04-17 | 2017-09-19 | Cristália Produtos Químicos Farmacêuticos Ltda. | Pharmaceutical composition for topic use containing heparin for the treatment of skin or mucosal injuries caused by burns |
| NZ577604A (en) * | 2006-11-15 | 2012-06-29 | Arthritis Relief Plus Ltd | Topical formulation and uses thereof |
| IT1400232B1 (it) * | 2010-05-07 | 2013-05-24 | Advance Holdings Ltd | Composizione farmaceutica topica comprendente eparina |
| CA2829241A1 (fr) * | 2011-04-01 | 2012-10-04 | University Of Florida Research Foundation, Inc. | Formulations thermosensibles, mucoadhesives ou dermoadhesives et ameliorant la penetration pour l'administration topique de produits therapeutiques |
-
2015
- 2015-02-10 CA CA2938388A patent/CA2938388C/fr active Active
- 2015-02-10 AU AU2015213569A patent/AU2015213569B2/en not_active Ceased
- 2015-02-10 MY MYPI2016702732A patent/MY182620A/en unknown
- 2015-02-10 US US15/116,060 patent/US9861655B2/en not_active Expired - Fee Related
- 2015-02-10 CN CN201580007796.6A patent/CN106163498A/zh active Pending
- 2015-02-10 PE PE2016001445A patent/PE20161173A1/es unknown
- 2015-02-10 AP AP2016009350A patent/AP2016009350A0/en unknown
- 2015-02-10 AR ARP150100384A patent/AR099333A1/es unknown
- 2015-02-10 NZ NZ722830A patent/NZ722830A/en not_active IP Right Cessation
- 2015-02-10 CU CU2016000119A patent/CU24444B1/es unknown
- 2015-02-10 JP JP2016568157A patent/JP6275877B2/ja not_active Expired - Fee Related
- 2015-02-10 DK DK15710252.6T patent/DK3104839T3/da active
- 2015-02-10 TW TW104104460A patent/TWI538697B/zh not_active IP Right Cessation
- 2015-02-10 MX MX2016010399A patent/MX357765B/es active IP Right Grant
- 2015-02-10 WO PCT/IB2015/050986 patent/WO2015118512A1/fr not_active Ceased
- 2015-02-10 EP EP15710252.6A patent/EP3104839B1/fr active Active
- 2015-02-10 EA EA201691596A patent/EA032200B1/ru unknown
- 2015-02-10 KR KR1020167023895A patent/KR101822133B1/ko not_active Expired - Fee Related
- 2015-02-10 MA MA39304A patent/MA39304B1/fr unknown
- 2015-02-10 UA UAA201608842A patent/UA118279C2/uk unknown
-
2016
- 2016-07-27 IL IL246974A patent/IL246974B/en active IP Right Grant
- 2016-07-28 PH PH12016501500A patent/PH12016501500B1/en unknown
- 2016-08-02 CL CL2016001952A patent/CL2016001952A1/es unknown
- 2016-08-03 DO DO2016000198A patent/DOP2016000198A/es unknown
- 2016-08-26 EC ECIEPI201669947A patent/ECSP16069947A/es unknown
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