ECSP16069947A - Formulaciones tópicas de heparina - Google Patents
Formulaciones tópicas de heparinaInfo
- Publication number
- ECSP16069947A ECSP16069947A ECIEPI201669947A ECPI201669947A ECSP16069947A EC SP16069947 A ECSP16069947 A EC SP16069947A EC IEPI201669947 A ECIEPI201669947 A EC IEPI201669947A EC PI201669947 A ECPI201669947 A EC PI201669947A EC SP16069947 A ECSP16069947 A EC SP16069947A
- Authority
- EC
- Ecuador
- Prior art keywords
- present
- formulations
- topical
- heparin formulations
- topical heparin
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002897 heparin Drugs 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 239000012049 topical pharmaceutical composition Substances 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000012669 liquid formulation Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se relaciona con formulaciones tópicas avanzadas de sales farmacéuticamente aceptables de Heparina que proporcionan penetración transdérmica mejorada. La presente invención proporciona formulaciones líquidas, no pegajosas, claras en las que el fármaco está listo para absorción y que son adecuadas para administración en la forma de una solución o una pulverización. Las formulaciones tópicas de la presente invención no forman película con escamas o similar a gel sobre la superficie de la piel luego de aplicación tópica.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN475MU2014 | 2014-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP16069947A true ECSP16069947A (es) | 2018-06-30 |
Family
ID=52684592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECIEPI201669947A ECSP16069947A (es) | 2014-02-10 | 2016-08-26 | Formulaciones tópicas de heparina |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US9861655B2 (es) |
| EP (1) | EP3104839B1 (es) |
| JP (1) | JP6275877B2 (es) |
| KR (1) | KR101822133B1 (es) |
| CN (1) | CN106163498A (es) |
| AP (1) | AP2016009350A0 (es) |
| AR (1) | AR099333A1 (es) |
| AU (1) | AU2015213569B2 (es) |
| CA (1) | CA2938388C (es) |
| CL (1) | CL2016001952A1 (es) |
| CU (1) | CU24444B1 (es) |
| DK (1) | DK3104839T3 (es) |
| DO (1) | DOP2016000198A (es) |
| EA (1) | EA032200B1 (es) |
| EC (1) | ECSP16069947A (es) |
| IL (1) | IL246974B (es) |
| MA (1) | MA39304B1 (es) |
| MX (1) | MX357765B (es) |
| MY (1) | MY182620A (es) |
| NZ (1) | NZ722830A (es) |
| PE (1) | PE20161173A1 (es) |
| PH (1) | PH12016501500A1 (es) |
| TW (1) | TWI538697B (es) |
| UA (1) | UA118279C2 (es) |
| WO (1) | WO2015118512A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011130455A1 (en) * | 2010-04-13 | 2011-10-20 | Najib Babul | Dermal pharmaceutical compositions of 1-methyl-2',6'-pipecoloxylidide and method of use |
| CN112546061B (zh) * | 2021-02-25 | 2021-06-11 | 中南大学湘雅医院 | 一种肝素类药物组合物、喷鼻剂及其制备方法及应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3323389A1 (de) * | 1983-06-29 | 1985-01-10 | B. Braun Melsungen Ag, 3508 Melsungen | Auf schleimhaeute des mundes, der nase und/oder des rachens wirkende arzneimittel auf der basis von heparin und tensiden |
| JPH02207018A (ja) * | 1989-02-07 | 1990-08-16 | Kao Corp | 皮膚外用剤 |
| DE19536244A1 (de) | 1994-09-30 | 1996-04-04 | Juergen Dr Regenold | Pharmazeutische Zusammensetzung zur lokalen Applikation |
| IT1275955B1 (it) | 1995-03-22 | 1997-10-24 | Dompe Spa | Formulazioni farmaceutiche in forma di gel tissotropico |
| JPH10279466A (ja) * | 1997-04-07 | 1998-10-20 | Kose Corp | 外用剤 |
| US6761903B2 (en) | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
| BRPI0101486B1 (pt) | 2001-04-17 | 2017-09-19 | Cristália Produtos Químicos Farmacêuticos Ltda. | Pharmaceutical composition for topic use containing heparin for the treatment of skin or mucosal injuries caused by burns |
| RU2467759C2 (ru) * | 2006-11-15 | 2012-11-27 | Артрайтис Рилиф Плас Лтд | Состав для местного использования и его применения |
| IT1400232B1 (it) * | 2010-05-07 | 2013-05-24 | Advance Holdings Ltd | Composizione farmaceutica topica comprendente eparina |
| RU2013147883A (ru) * | 2011-04-01 | 2015-05-10 | Юниверсити Оф Флорида Рисеч Фаундэйшн, Инк. | Термочувствительные, мукоадгезивные или кожно-адгезивные и усиливающие проникновение композиции для местной доставки терапевтических средств |
-
2015
- 2015-02-10 AP AP2016009350A patent/AP2016009350A0/en unknown
- 2015-02-10 DK DK15710252.6T patent/DK3104839T3/da active
- 2015-02-10 MA MA39304A patent/MA39304B1/fr unknown
- 2015-02-10 UA UAA201608842A patent/UA118279C2/uk unknown
- 2015-02-10 EP EP15710252.6A patent/EP3104839B1/en active Active
- 2015-02-10 EA EA201691596A patent/EA032200B1/ru unknown
- 2015-02-10 US US15/116,060 patent/US9861655B2/en not_active Expired - Fee Related
- 2015-02-10 MX MX2016010399A patent/MX357765B/es active IP Right Grant
- 2015-02-10 AU AU2015213569A patent/AU2015213569B2/en not_active Ceased
- 2015-02-10 CN CN201580007796.6A patent/CN106163498A/zh active Pending
- 2015-02-10 NZ NZ722830A patent/NZ722830A/en not_active IP Right Cessation
- 2015-02-10 CU CU2016000119A patent/CU24444B1/es unknown
- 2015-02-10 PE PE2016001445A patent/PE20161173A1/es unknown
- 2015-02-10 JP JP2016568157A patent/JP6275877B2/ja not_active Expired - Fee Related
- 2015-02-10 KR KR1020167023895A patent/KR101822133B1/ko not_active Expired - Fee Related
- 2015-02-10 TW TW104104460A patent/TWI538697B/zh not_active IP Right Cessation
- 2015-02-10 WO PCT/IB2015/050986 patent/WO2015118512A1/en not_active Ceased
- 2015-02-10 MY MYPI2016702732A patent/MY182620A/en unknown
- 2015-02-10 AR ARP150100384A patent/AR099333A1/es unknown
- 2015-02-10 CA CA2938388A patent/CA2938388C/en active Active
-
2016
- 2016-07-27 IL IL246974A patent/IL246974B/en active IP Right Grant
- 2016-07-28 PH PH12016501500A patent/PH12016501500A1/en unknown
- 2016-08-02 CL CL2016001952A patent/CL2016001952A1/es unknown
- 2016-08-03 DO DO2016000198A patent/DOP2016000198A/es unknown
- 2016-08-26 EC ECIEPI201669947A patent/ECSP16069947A/es unknown
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