DZ2128A1 - Composés nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant. - Google Patents

Composés nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.

Info

Publication number: DZ2128A1
Authority: DZ; Algeria
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; new compounds; compounds
Prior art date: 1995-11-24

Application number

DZ960173A

Other languages

English (en)

Original Assignee

Smithkline Beecham Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-24

Filing date

1996-11-23

Publication date

2002-10-26

1995-11-24 Priority claimed from IT95MI002462 external-priority patent/IT1276171B1/it

1996-08-02 Priority claimed from ITMI961688 external-priority patent/IT1307330B1/it

1996-11-23 Application filed by Smithkline Beecham Spa filed Critical Smithkline Beecham Spa

2002-10-26 Application granted granted Critical

2002-10-26 Publication of DZ2128A1 publication Critical patent/DZ2128A1/fr

Links

150000001875 compounds Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Immunology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DZ960173A 1995-11-24 1996-11-23 Composés nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant. DZ2128A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT95MI002462 IT1276171B1 (it)	1995-11-24	1995-11-24	Derivati chinolinici
ITMI961688 IT1307330B1 (it)	1996-08-02	1996-08-02	Derivati chinolinici

Publications (1)

Publication Number	Publication Date
DZ2128A1 true DZ2128A1 (fr)	2002-10-26

Family

ID=26331327

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ960173A DZ2128A1 (fr)	1995-11-24	1996-11-23	Composés nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.

Country Status (26)

Country	Link
US (1)	US20020068827A1 (fr)
EP (1)	EP1019377A1 (fr)
JP (1)	JP2000513325A (fr)
KR (1)	KR19990071598A (fr)
CN (1)	CN1207729A (fr)
AP (1)	AP9801238A0 (fr)
AR (1)	AR004735A1 (fr)
AU (1)	AU1031897A (fr)
BG (1)	BG102557A (fr)
BR (1)	BR9611757A (fr)
CA (1)	CA2238328A1 (fr)
CZ (1)	CZ158098A3 (fr)
DZ (1)	DZ2128A1 (fr)
EA (1)	EA001771B1 (fr)
HU (1)	HUP9901016A3 (fr)
IL (1)	IL124418A0 (fr)
MA (1)	MA24011A1 (fr)
MX (1)	MX9804108A (fr)
NO (1)	NO311213B1 (fr)
OA (1)	OA11011A (fr)
PL (1)	PL326928A1 (fr)
SK (1)	SK66898A3 (fr)
TR (1)	TR199800883T2 (fr)
TW (1)	TW409123B (fr)
UY (2)	UY24375A1 (fr)
WO (1)	WO1997019926A1 (fr)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1491533A3 (fr) *	1997-03-14	2005-01-19	Cephalon, Inc.	Quinoline- et naphthalenecarboxamides, leurs compositions pharmaceutiques et leur utilisation en tant qu'inhibiteurs de la calpaine
EP0983262B1 (fr) *	1997-05-23	2003-07-09	GlaxoSmithKline S.p.A.	Derives de quinoline-4-carboxamide comme antagonistes des recepteurs nk-2 et nk-3
US6339089B2 (en)	1997-08-13	2002-01-15	Fujirebio Inc.	Pyrimidine nucleus-containing compound and a medicament containing the same for a blood oxygen partial pressure amelioration, and a method for preparing the same
US6262070B1 (en)	1998-11-04	2001-07-17	Darwin Discovery Ltd.	Heterocyclic compounds and their therapeutic use
GB9825554D0 (en)	1998-11-20	1999-01-13	Smithkline Beecham Spa	Novel Compounds
US6780875B2 (en) *	1998-11-20	2004-08-24	Smithkline Beecham S.P.A.	Quinoline-4-carboxamide derivatives as NK-3 and NK-2 receptor antagonists
JP2002530377A (ja) *	1998-11-20	2002-09-17	スミスクライン・ビーチャム・ソシエタ・ペル・アチオニ	Ｎｋ−３およびｎｋ−２受容体アンタゴニストとしてのキノリン−４−カルボキシアミド誘導体
PT1035115E (pt) *	1999-02-24	2005-01-31	Hoffmann La Roche	Derivados de 4-fenilpiridina e a sua utilizacao como antagonistas do receptor nk-1
CA2365401A1 (fr) *	1999-03-11	2000-10-05	Neurogen Corporation	Pyridines 2,4-disubstituees fusionnees avec un aryle: ligands du recepteur nk-3
US7037922B1 (en)	2000-03-10	2006-05-02	Neurogen Corporation	Aryl fused 2,4-disubstituted pyridines: NK3 receptor ligands
AU4038000A (en)	1999-03-29	2000-10-16	Neurogen Corporation	4-substituted quinoline derivatives as gaba receptor ligands
WO2000064877A1 (fr)	1999-04-26	2000-11-02	Neurogen Corporation	2-aminoquinolinecarboxamides: ligands de recepteurs de la neurokinine
TWI259180B (en) *	2000-08-08	2006-08-01	Hoffmann La Roche	4-Phenyl-pyridine derivatives
WO2002013825A1 (fr) *	2000-08-11	2002-02-21	Smithkline Beecham P.L.C.	Nouvelle utilisation pharmaceutique de dérivés quinnoliniques
EP1334089A1 (fr) *	2000-11-13	2003-08-13	GlaxoSmithKline S.p.A.	Derives de la quinoline en tant qu'antagonistes de nk-3 et nk-2
GB0028964D0 (en) *	2000-11-28	2001-01-10	Smithkline Beecham Spa	Novel compounds
US6540733B2 (en)	2000-12-29	2003-04-01	Corazon Technologies, Inc.	Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occlusion
GB0109122D0 (en) *	2001-04-11	2001-05-30	Smithkline Beecham Spa	Novel compounds
DE60209362T2 (de) *	2001-04-11	2006-10-26	Glaxosmithkline S.P.A.	3-substituierte chinolin-4-carbonsäureamidderivate als nk-3- und nk-2-rezeptorantagonisten
MY134211A (en) *	2001-05-18	2007-11-30	Smithkline Beecham Corp	Novel use
WO2004002484A1 (fr) *	2002-06-26	2004-01-08	Kyowa Hakko Kogyo Co., Ltd.	Inhibiteur de phosphodiesterase
GB0312609D0 (en)	2003-06-02	2003-07-09	Astrazeneca Ab	Novel compounds
JP2007521276A (ja) *	2003-06-25	2007-08-02	スミスクライン・ビーチャム・コーポレイション	Ｎｋ−２およびｎｋ−３として用いるための４−カルボキサミドキノリン誘導体
US7288658B2 (en)	2003-07-15	2007-10-30	Hoffmann-La Roche Inc.	Process for preparation of pyridine derivatives
SE0302139D0 (sv) *	2003-07-28	2003-07-28	Astrazeneca Ab	Novel compounds
GB0318727D0 (en) *	2003-08-08	2003-09-10	Smithkline Beecham Corp	Novel compounds
GB0425077D0 (en) *	2004-11-12	2004-12-15	Smithkline Beecham Corp	Novel compounds
MX2007014831A (es) *	2005-06-03	2008-02-15	Astrazeneca Ab	Derivados de quinolina como antagonistas de neurocinina-3.
JP2008546767A (ja) *	2005-06-23	2008-12-25	アストラゼネカ・アクチエボラーグ	Ｎｋ３受容体のモジュレーターとしてのキノリン３−スルホン酸エステル
GB0515580D0 (en)	2005-07-29	2005-09-07	Merck Sharp & Dohme	Therapeutic compounds
CN101287723A (zh) *	2005-08-11	2008-10-15	阿斯利康(瑞典)有限公司	作为nk3受体调节剂的酰胺烷基吡啶基喹啉
EP1915361A1 (fr) *	2005-08-11	2008-04-30	AstraZeneca AB	Alkylpyridyl quinolines en tant que modulateurs du récepteur des nk3
CN101282964A (zh) *	2005-08-11	2008-10-08	阿斯利康(瑞典)有限公司	作为nk3受体调节剂的氧-吡啶基喹啉酰胺
AR057130A1 (es)	2005-09-21	2007-11-14	Astrazeneca Ab	Quinolinas de alquilsulfoxido y una composicion farmaceutica
AR058051A1 (es) *	2005-09-21	2008-01-23	Astrazeneca Ab	Quinolinas de alquilnitrilo.proceso de obtencion y composiciones farmaceuticas.
TW200804288A (en)	2005-12-12	2008-01-16	Astrazeneca Ab	Alkylsulphonamide quinolines
CA2680761A1 (fr)	2007-03-22	2008-09-25	Astrazeneca Ab	Derives de quinoleine destines au traitement de maladies inflammatoires
PE20091036A1 (es)	2007-11-30	2009-08-15	Astrazeneca Ab	Derivado de quinolina como antagonista del receptor p2x7
CN102924375B (zh) *	2012-06-21	2015-02-18	江苏恩华药业股份有限公司	Talnetant中间体及其制备方法和应用
WO2014170648A1 (fr)	2013-04-19	2014-10-23	Astrazeneca Ab	Composé antagoniste du récepteur nk3 (nk3ra) utilisé dans une méthode pour traiter le syndrome des ovaires polykystiques (sopk)
EP3191452A1 (fr)	2014-09-09	2017-07-19	Bayer Pharma Aktiengesellschaft	N,2-diarylquinoline-4-carboxamides substitués et utilisation desdits n,2-diarylquinoline-4-carboxamides substitués comme anti-inflammatoires
US10117864B2 (en)	2015-03-18	2018-11-06	Bayer Pharma Aktiengesellschaft	Substituted N-bicyclo-2-aryl-quinolin-4-carboxamides and use thereof
WO2017072629A1 (fr)	2015-10-29	2017-05-04	Cadila Healthcare Limited	Combinaison pharmaceutique d'antagoniste du récepteur nk3 et de biguanides
WO2017153234A1 (fr)	2016-03-09	2017-09-14	Bayer Pharma Aktiengesellschaft	N-cyclo-2-arylchinolin-4-carboxamides substitués et leur utilisation
WO2017153235A1 (fr)	2016-03-09	2017-09-14	Bayer Pharma Aktiengesellschaft	N-cyclo-3-aryl-1-naphthamides substitués et leur utilisation
WO2017153231A1 (fr)	2016-03-09	2017-09-14	Bayer Pharma Aktiengesellschaft	N-cyclo-2-arylisochinolinon-4-carboxamides substitués et leur utilisation
TWI770157B (zh) *	2017-04-10	2022-07-11	德商拜耳廠股份有限公司	經取代之n-芳基乙基-2-胺基喹啉-4-甲醯胺及其用途
US11136296B2 (en) *	2017-04-10	2021-10-05	Bayer Aktiengesellschaft	Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2538388B1 (fr) *	1982-12-24	1985-06-21	Pharmuka Lab	Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments
DK623586A (da) *	1985-12-27	1987-06-28	Eisai Co Ltd	Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
EP0585913B1 (fr) *	1992-09-04	1997-12-29	Takeda Chemical Industries, Ltd.	Composés hétérocycliques condensés, leur production et usage
SK282721B6 (sk) *	1994-05-27	2002-11-06	Smithkline Beecham S.P.A.	Nepeptidové NK3 antagonistické látky, spôsob ich výroby, farmaceutické prostriedky s ich obsahom a ich použitie
IT1270615B (it) *	1994-07-14	1997-05-07	Smithkline Beecham Farma	Uso di derivati di chinolina

1996
- 1996-11-21 AR ARP960105282A patent/AR004735A1/es unknown
- 1996-11-22 SK SK668-98A patent/SK66898A3/sk unknown
- 1996-11-22 BR BR9611757A patent/BR9611757A/pt unknown
- 1996-11-22 MA MA24399A patent/MA24011A1/fr unknown
- 1996-11-22 EP EP96941025A patent/EP1019377A1/fr not_active Withdrawn
- 1996-11-22 CA CA002238328A patent/CA2238328A1/fr not_active Abandoned
- 1996-11-22 PL PL96326928A patent/PL326928A1/xx unknown
- 1996-11-22 UY UY24375A patent/UY24375A1/es not_active IP Right Cessation
- 1996-11-22 KR KR1019980703874A patent/KR19990071598A/ko not_active Withdrawn
- 1996-11-22 AU AU10318/97A patent/AU1031897A/en not_active Abandoned
- 1996-11-22 HU HU9901016A patent/HUP9901016A3/hu unknown
- 1996-11-22 EA EA199800538A patent/EA001771B1/ru not_active IP Right Cessation
- 1996-11-22 TR TR1998/00883T patent/TR199800883T2/xx unknown
- 1996-11-22 WO PCT/EP1996/005207 patent/WO1997019926A1/fr not_active Ceased
- 1996-11-22 AP APAP/P/1998/001238A patent/AP9801238A0/en unknown
- 1996-11-22 IL IL12441896A patent/IL124418A0/xx unknown
- 1996-11-22 CN CN96199747A patent/CN1207729A/zh active Pending
- 1996-11-22 CZ CZ981580A patent/CZ158098A3/cs unknown
- 1996-11-22 JP JP09520158A patent/JP2000513325A/ja active Pending
- 1996-11-23 DZ DZ960173A patent/DZ2128A1/fr active
- 1996-11-23 TW TW085114501A patent/TW409123B/zh not_active IP Right Cessation
1997
- 1997-05-16 UY UY24555A patent/UY24555A1/es not_active Application Discontinuation
1998
- 1998-05-22 OA OA9800062A patent/OA11011A/en unknown
- 1998-05-22 NO NO19982333A patent/NO311213B1/no not_active IP Right Cessation
- 1998-05-22 MX MX9804108A patent/MX9804108A/es unknown
- 1998-06-18 BG BG102557A patent/BG102557A/bg unknown
2001
- 2001-11-26 US US09/994,402 patent/US20020068827A1/en not_active Abandoned

Also Published As

Publication number	Publication date
BG102557A (bg)	1999-03-31
MA24011A1 (fr)	1997-07-01
NO982333L (no)	1998-07-22
MX9804108A (es)	1998-09-30
AP9801238A0 (en)	1998-06-30
JP2000513325A (ja)	2000-10-10
CA2238328A1 (fr)	1997-06-05
CN1207729A (zh)	1999-02-10
HUP9901016A3 (en)	2002-01-28
KR19990071598A (ko)	1999-09-27
EA001771B1 (ru)	2001-08-27
PL326928A1 (en)	1998-11-09
NO311213B1 (no)	2001-10-29
OA11011A (en)	2003-03-06
NO982333D0 (no)	1998-05-22
CZ158098A3 (cs)	1998-10-14
HUP9901016A2 (hu)	2000-03-28
UY24375A1 (es)	1997-05-22
WO1997019926A1 (fr)	1997-06-05
SK66898A3 (en)	1998-12-02
AR004735A1 (es)	1999-03-10
AU1031897A (en)	1997-06-19
EA199800538A1 (ru)	1998-12-24
EP1019377A1 (fr)	2000-07-19
BR9611757A (pt)	1999-04-06
TR199800883T2 (xx)	2000-12-21
UY24555A1 (es)	2001-04-30
IL124418A0 (en)	1998-12-06
TW409123B (en)	2000-10-21
US20020068827A1 (en)	2002-06-06

Publication	Publication Date	Title
DZ2128A1 (fr)	2002-10-26	Composés nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ1889A1 (fr)	2002-02-17	Dérivés de quinoléine nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
CY2537B1 (fr)	2006-06-28	Composés hétérocycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant
DZ1957A1 (fr)	2002-02-17	Dérivés de pipéridine nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2300A1 (fr)	2002-12-25	Dérivés 6,5-hétérobicycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2299A1 (fr)	2002-12-25	Dérivés 6,6-hétérobicycliques substitués, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2197A1 (fr)	2002-12-02	Dérivés de 6-phénylpyridyl-2-amine, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2891A1 (fr)	2003-12-15	Dérivés de tétrahydroquinoléines substués nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2890A1 (fr)	2003-12-15	4-Carboxamino-2-substitué-1,2,3,4-tétrahydroquinoléines, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2045A1 (fr)	2002-07-21	Amides thérapeutiques, procédé pour leur préparation et compositions les contenant.
DZ2303A1 (fr)	2002-12-28	Dérivés d'indazole nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.
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DZ2227A1 (fr)	2002-12-25	Dérivés d'indole nouveaux, procédé pour leur préparation et formulations pharmaceutiques les contenant.
DZ2962A1 (fr)	2004-03-15	Dérivés de 3-azabicycloÄ3,1,0Ühexane nouveaux, procédé pour leur préparation et compositions les contenant.
DZ2634A1 (fr)	2003-03-08	Dérivés de pleuromutiline nouveaux procédé pour leur préparation et compositions pharmaceutiques lescontenant.
DZ2889A1 (fr)	2003-12-15	4-Carboxyamino-2-méthyl-1,2,3,4-tétrahydroquinoléines, procédé pour leur préparation et compositionspharmaceutiques les contenant.
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DZ2745A1 (fr)	2003-09-08	BicycloÄ2.2.1Üheptanes nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2963A1 (fr)	2004-03-15	Dérivés de bicycliques substituées nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2217A1 (fr)	2002-12-03	Dérivés d'imidazole substitués, procédé pour leur préparation et compositions les contenant.
DZ2777A1 (fr)	2003-12-01	Dérivés de quinazolinamines nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.
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DZ2414A1 (fr)	2003-01-04	2-amino-6-(2-substitué-4-phenoxy)substituté-pyridines procédé pour leur préparation et compositions pharmaceutiques les contenant.