DZ2892A1 - Livraison d'agent actif atomisé par modulation résistance de débit. - Google Patents

Livraison d'agent actif atomisé par modulation résistance de débit.

Info

Publication number
DZ2892A1
DZ2892A1 DZ990192A DZ990192A DZ2892A1 DZ 2892 A1 DZ2892 A1 DZ 2892A1 DZ 990192 A DZ990192 A DZ 990192A DZ 990192 A DZ990192 A DZ 990192A DZ 2892 A1 DZ2892 A1 DZ 2892A1
Authority
DZ
Algeria
Prior art keywords
delivery
active agent
flow resistance
resistance modulation
atomized active
Prior art date
Application number
DZ990192A
Other languages
English (en)
French (fr)
Inventor
Andrew Clark
Original Assignee
Inhale Therapeutic Syst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhale Therapeutic Syst filed Critical Inhale Therapeutic Syst
Application granted granted Critical
Publication of DZ2892A1 publication Critical patent/DZ2892A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DZ990192A 1998-09-14 1999-09-13 Livraison d'agent actif atomisé par modulation résistance de débit. DZ2892A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10016398P 1998-09-14 1998-09-14

Publications (1)

Publication Number Publication Date
DZ2892A1 true DZ2892A1 (fr) 2003-12-15

Family

ID=22278404

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ990192A DZ2892A1 (fr) 1998-09-14 1999-09-13 Livraison d'agent actif atomisé par modulation résistance de débit.

Country Status (44)

Country Link
EP (1) EP1117442A1 (is)
JP (1) JP2002524535A (is)
KR (1) KR20010075063A (is)
CN (1) CN1317977A (is)
AP (1) AP1374A (is)
AR (1) AR022090A1 (is)
AU (1) AU753014B2 (is)
BG (1) BG105430A (is)
BR (1) BR9913722A (is)
CA (1) CA2343920A1 (is)
CO (1) CO5130023A1 (is)
CZ (1) CZ2001829A3 (is)
DZ (1) DZ2892A1 (is)
EA (1) EA003476B1 (is)
EE (1) EE200100151A (is)
GE (1) GEP20043257B (is)
GT (1) GT199900156A (is)
HK (1) HK1042231A1 (is)
HN (1) HN1999000159A (is)
HR (1) HRP20010189A2 (is)
HU (1) HUP0103837A3 (is)
ID (1) ID28845A (is)
IL (2) IL141562A0 (is)
IS (1) IS5878A (is)
LT (1) LT4897B (is)
LV (1) LV12658B (is)
MA (1) MA25590A1 (is)
MY (1) MY129282A (is)
NO (1) NO20011251L (is)
NZ (1) NZ510168A (is)
OA (1) OA11781A (is)
PA (1) PA8481901A1 (is)
PE (1) PE20001061A1 (is)
PL (1) PL195574B1 (is)
SA (1) SA99200718B1 (is)
SK (1) SK3442001A3 (is)
TN (1) TNSN99173A1 (is)
TR (1) TR200101182T2 (is)
TW (1) TWI226248B (is)
UA (1) UA76085C2 (is)
UY (1) UY25711A1 (is)
WO (1) WO2000015262A1 (is)
YU (1) YU24201A (is)
ZA (1) ZA200101995B (is)

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US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
HK1049621A1 (zh) 1999-06-09 2003-05-23 罗伯特‧E‧希弗斯 超临界流体辅助的喷雾和鼓泡乾燥
US6475468B2 (en) * 2001-02-15 2002-11-05 Aeropharm Technology Incorporated Modulated release particles for aerosol delivery
JP2005503425A (ja) * 2001-05-24 2005-02-03 アレックザ モレキュラー デリヴァリー コーポレイション 所定の吸入ルートによる薬剤エステルの送出
EG24184A (en) 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
JP4368198B2 (ja) 2001-11-20 2009-11-18 アルカーメス,インコーポレイテッド 肺送達用の改良された粒状組成物
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
JP2005518453A (ja) 2002-02-25 2005-06-23 ディフュージョン・ファーマシューティカルズ・エルエルシー 二極性トランスカロテノイド塩およびそれらの使用
JP2006513139A (ja) * 2002-07-03 2006-04-20 ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド 治療薬の全身性送達のための中央部気道投与
CA2511385A1 (en) * 2002-12-19 2004-07-22 Pharmacia Corporation Non-hygroscopic formulation comprising a hydroscopic drug
DE10338403A1 (de) * 2003-08-18 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierung, enthaltend den CGRP-Antagonisten 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl]-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyrindinyl)-piperazin, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US20070020299A1 (en) 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
PL2708225T3 (pl) * 2004-04-23 2019-07-31 Cydex Pharmaceuticals, Inc. Formulacja DPI zawierająca eter sulfoalkilowy cyklodekstryny
KR101315904B1 (ko) 2005-02-24 2013-10-08 디퓨젼 파마슈티컬즈 엘엘씨 트랜스 카로티노이드, 이들의 합성, 제제화 및 용도
EP1857114A1 (en) * 2005-03-09 2007-11-21 Ono Pharmaceutical Co., Ltd. Particle and preparation containing the particle
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
EP2581078B1 (en) 2005-10-26 2014-12-10 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US20080035143A1 (en) * 2006-08-14 2008-02-14 Sievers Robert E Human-powered dry powder inhaler and dry powder inhaler compositions
JP5315056B2 (ja) * 2006-10-25 2013-10-16 大日本住友製薬株式会社 固結抑制粒状製剤
EP1925295A1 (de) * 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
EP2589588A1 (en) 2007-04-13 2013-05-08 Diffusion Pharmaceuticals Llc Use of bipolar trans carotenoids as a pretreatment and in the treatment of peripheral vascular disease
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
CN101878040A (zh) 2007-10-31 2010-11-03 扩散药品有限公司 一类促进小分子扩散的新型治疗剂
DK2432502T3 (en) 2009-05-20 2018-03-12 Aeras STABLE, SPRAY DRIED, IMMUNOGENE, VIRUS COMPOSITIONS
US10130689B2 (en) 2009-06-22 2018-11-20 Diffusion Pharmaceuticals Llc Diffusion enhancing compounds and their use alone or with thrombolytics
CN103124498A (zh) 2010-06-02 2013-05-29 扩散药品有限公司 双极性反式类胡萝卜素的口服制剂
BR112014026957A8 (pt) * 2012-05-03 2018-01-16 Janssen R&D Ireland micropartícula, composição compreendendo a mesma, seu uso e sistema de distribuição nasal relacionados ao tratamento de infecções do trato respiratório superior
WO2014074797A1 (en) * 2012-11-09 2014-05-15 Civitas Therapeutics, Inc. Ultra low density pulmonary powders
WO2015042352A1 (en) * 2013-09-20 2015-03-26 Virginia Commonwealth University Delivery of particles using hygroscopic excipients
AU2015338717B2 (en) 2014-10-31 2018-12-20 Glaxosmithkline Intellectual Property Development Limited Powder formulation
EP3432929A4 (en) 2016-03-24 2019-11-27 Diffusion Pharmaceuticals LLC USE OF BIPOLAR TRANSCAROTINOIDS WITH CHEMOTHERAPY AND RADIOTHERAPY FOR THE TREATMENT OF CANCER
US20220378727A1 (en) * 2021-05-14 2022-12-01 The University Of Hong Kong Dry powder formulations of tamibarotene for pulmonary and intranasal delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155573A (en) * 1958-05-06 1964-11-03 Benger Lab Ltd Inhalant composition and method of making same
EP0611567B1 (en) * 1992-06-12 2002-08-28 Teijin Limited Ultrafine powder for inhalation and production thereof
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
ES2236832T3 (es) * 1997-01-16 2005-07-16 Massachusetts Institute Of Technology Preparacion de particulas para inhalacion.
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant

Also Published As

Publication number Publication date
HK1042231A1 (zh) 2002-08-09
ID28845A (id) 2001-07-05
PL195574B1 (pl) 2007-10-31
MA25590A1 (fr) 2002-12-31
JP2002524535A (ja) 2002-08-06
LT4897B (lt) 2002-02-25
NO20011251D0 (no) 2001-03-13
EE200100151A (et) 2002-06-17
TR200101182T2 (tr) 2001-09-21
HRP20010189A2 (en) 2005-04-30
LT2001021A (en) 2001-11-26
NZ510168A (en) 2003-09-26
TNSN99173A1 (fr) 2005-11-10
SA99200718B1 (ar) 2006-11-04
OA11781A (en) 2005-07-26
AR022090A1 (es) 2002-09-04
NO20011251L (no) 2001-04-17
YU24201A (sh) 2003-08-29
EA003476B1 (ru) 2003-06-26
TWI226248B (en) 2005-01-11
EA200100300A1 (ru) 2001-10-22
UY25711A1 (es) 1999-11-17
AP2001002093A0 (en) 2001-03-31
IS5878A (is) 2001-03-05
PA8481901A1 (es) 2002-04-25
HUP0103837A3 (en) 2002-11-28
CA2343920A1 (en) 2000-03-23
CN1317977A (zh) 2001-10-17
IL141562A0 (en) 2002-03-10
CZ2001829A3 (cs) 2001-09-12
ZA200101995B (en) 2002-03-11
PE20001061A1 (es) 2000-10-08
UA76085C2 (en) 2006-07-17
GT199900156A (es) 2001-03-07
HUP0103837A2 (hu) 2002-05-29
BR9913722A (pt) 2001-05-29
BG105430A (en) 2001-12-29
IL141562A (en) 2007-07-24
AU6039799A (en) 2000-04-03
CO5130023A1 (es) 2002-02-27
GEP20043257B (en) 2004-06-25
HN1999000159A (es) 1999-11-11
AU753014B2 (en) 2002-10-03
KR20010075063A (ko) 2001-08-09
WO2000015262A1 (en) 2000-03-23
LV12658B (lv) 2001-09-20
AP1374A (en) 2005-02-28
SK3442001A3 (en) 2001-11-06
PL346768A1 (en) 2002-02-25
MY129282A (en) 2007-03-30
LV12658A (lv) 2001-05-20
EP1117442A1 (en) 2001-07-25

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