DZ3030A1 - Procédé et produits intermédiaires pour la préparation de composés anti-cancéreux. - Google Patents

Procédé et produits intermédiaires pour la préparation de composés anti-cancéreux.

Info

Publication number: DZ3030A1
Authority: DZ; Algeria
Prior art keywords: preparation; intermediate products; cancer compounds; cancer; compounds
Prior art date: 1999-03-31

Application number

DZ000059A

Other languages

English (en)

French (fr)

Inventor

Richard Shelton Lehner

Timothy Norris

Dinos Paul Santafianos

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-31

Filing date

2000-03-29

Publication date

2004-03-27

2000-03-29 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2004-03-27 Application granted granted Critical

2004-03-27 Publication of DZ3030A1 publication Critical patent/DZ3030A1/xx

Links

230000001093 anti-cancer Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000013067 intermediate product Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
- C22B15/00—Obtaining copper
- C22B15/0002—Preliminary treatment
- C22B15/0004—Preliminary treatment without modification of the copper constituent
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22B—PRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
- C22B15/00—Obtaining copper
- C22B15/0063—Hydrometallurgy
- C22B15/0065—Leaching or slurrying
- C22B15/0067—Leaching or slurrying with acids or salts thereof
- C22B15/0071—Leaching or slurrying with acids or salts thereof containing sulfur
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P10/00—Technologies related to metal processing
- Y02P10/20—Recycling

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Mechanical Engineering (AREA)
Manufacturing & Machinery (AREA)
Metallurgy (AREA)
Materials Engineering (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

DZ000059A 1999-03-31 2000-03-29 Procédé et produits intermédiaires pour la préparation de composés anti-cancéreux. DZ3030A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US12707299P	1999-03-31	1999-03-31

Publications (1)

Publication Number	Publication Date
DZ3030A1 true DZ3030A1 (fr)	2004-03-27

Family

ID=22428179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ000059A DZ3030A1 (fr)	1999-03-31	2000-03-29	Procédé et produits intermédiaires pour la préparation de composés anti-cancéreux.

Country Status (49)

Country	Link
US (1)	US6476040B1 (es)
EP (1)	EP1044969B1 (es)
JP (2)	JP3420549B2 (es)
KR (2)	KR100430210B1 (es)
CN (2)	CN100351242C (es)
AP (2)	AP1655A (es)
AR (1)	AR018705A1 (es)
AT (1)	ATE348098T1 (es)
AU (2)	AU781402B2 (es)
BG (1)	BG65194B1 (es)
BR (1)	BRPI0001486B8 (es)
CA (2)	CA2427221C (es)
CO (1)	CO5160273A1 (es)
CR (1)	CR6165A (es)
CZ (1)	CZ299426B6 (es)
DE (1)	DE60032275T2 (es)
DK (1)	DK1044969T3 (es)
DZ (1)	DZ3030A1 (es)
EA (3)	EA004654B1 (es)
EE (1)	EE04589B1 (es)
EG (1)	EG22506A (es)
ES (1)	ES2278578T3 (es)
GE (1)	GEP20022653B (es)
GT (1)	GT200000037A (es)
HR (1)	HRP20000182B1 (es)
HU (1)	HU227698B1 (es)
ID (1)	ID25427A (es)
IL (2)	IL168036A (es)
IS (1)	IS2468B (es)
MA (1)	MA25087A1 (es)
MY (1)	MY136270A (es)
NO (2)	NO321952B1 (es)
NZ (2)	NZ503683A (es)
OA (1)	OA11335A (es)
PA (1)	PA8491901A1 (es)
PE (1)	PE20001599A1 (es)
PL (1)	PL339330A1 (es)
PT (1)	PT1044969E (es)
RS (1)	RS49836B (es)
SG (2)	SG115536A1 (es)
SK (1)	SK287339B6 (es)
SV (1)	SV2002000047A (es)
TN (1)	TNSN00064A1 (es)
TR (1)	TR200000837A2 (es)
TW (1)	TW553939B (es)
UA (2)	UA80955C2 (es)
UY (1)	UY26086A1 (es)
YU (1)	YU13200A (es)
ZA (1)	ZA200001586B (es)

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AU9598601A (en)	2000-10-20	2002-04-29	Eisai Co Ltd	Nitrogenous aromatic ring compounds
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US7078409B2 (en)	2002-03-28	2006-07-18	Beta Pharma, Inc.	Fused quinazoline derivatives useful as tyrosine kinase inhibitors
US7576074B2 (en)	2002-07-15	2009-08-18	Rice Kenneth D	Receptor-type kinase modulators and methods of use
US7148231B2 (en)	2003-02-17	2006-12-12	Hoffmann-La Roche Inc.	[6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride polymorph
ATE508747T1 (de)	2003-03-10	2011-05-15	Eisai R&D Man Co Ltd	C-kit kinase-hemmer
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AU2004253967B2 (en)	2003-07-03	2010-02-18	Cytovia, Inc.	4-arylamino-quinazolines as activators of caspases and inducers of apoptosis
WO2006074147A2 (en)	2005-01-03	2006-07-13	Myriad Genetics, Inc.	Nitrogen containing bicyclic compounds and therapeutical use thereof
ATE395346T1 (de)	2003-09-16	2008-05-15	Astrazeneca Ab	Chinazolinderivate als tyrosinkinaseinhibitoren
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US7683172B2 (en)	2003-11-11	2010-03-23	Eisai R&D Management Co., Ltd.	Urea derivative and process for preparing the same
KR20080095915A (ko) *	2004-05-06	2008-10-29	워너-램버트 캄파니 엘엘씨	4-페닐아미노-퀴나졸린-6-일-아미드
ATE428421T1 (de)	2004-09-17	2009-05-15	Eisai R&D Man Co Ltd	Medizinische zusammensetzung mit verbesserter stabilität und reduzierten gelierungseigenschaften
US8258145B2 (en)	2005-01-03	2012-09-04	Myrexis, Inc.	Method of treating brain cancer
US7625911B2 (en) *	2005-01-12	2009-12-01	Mai De Ltd.	Amorphous form of erlotinib hydrochloride and its solid amorphous dispersion
SI1859793T1 (sl) *	2005-02-28	2011-08-31	Eisai R&D Man Co Ltd	Nova kombinirana uporaba sulfonamidne spojine za zdravljenje raka
WO2007015569A1 (ja) *	2005-08-01	2007-02-08	Eisai R & D Management Co., Ltd.	血管新生阻害物質の効果を予測する方法
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CN104706637A (zh) *	2006-05-18	2015-06-17	卫材R&D管理有限公司	针对甲状腺癌的抗肿瘤剂
JPWO2008001956A1 (ja) *	2006-06-29	2009-12-03	エーザイ・アール・アンド・ディー・マネジメント株式会社	肝線維症治療剤
CA2659307A1 (en)	2006-07-28	2008-01-31	Synthon B.V.	Crystalline erlotinib
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US8372856B2 (en) *	2006-10-27	2013-02-12	Synthon Bv	Hydrates of erlotinib hydrochloride
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CN102438995B (zh)	2009-03-26	2014-12-17	兰贝克赛实验室有限公司	厄洛替尼或其药学上可接受的盐的制备工艺
UA108618C2 (uk)	2009-08-07	2015-05-25		Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку
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EP2499118A2 (en)	2009-11-12	2012-09-19	Ranbaxy Laboratories Limited	Processes for the preparation of erlotinib hydrochloride form a and erlotinib hydrochloride form b
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IT1402029B1 (it)	2010-10-14	2013-08-28	Italiana Sint Spa	Procedimento per la preparazione di erlotinib
CN103402519B (zh)	2011-04-18	2015-11-25	卫材R&D管理有限公司	肿瘤治疗剂
JP6038128B2 (ja)	2011-06-03	2016-12-07	エーザイ・アール・アンド・ディー・マネジメント株式会社	レンバチニブ化合物に対する甲状腺癌対象及び腎臓癌対象の反応性を予測及び評価するためのバイオマーカー
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CN103420924B (zh) *	2012-05-25	2016-08-31	浙江九洲药业股份有限公司	一种盐酸埃罗替尼晶型a的制备方法
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KR20150098605A (ko)	2012-12-21	2015-08-28	에자이 알앤드디 매니지먼트 가부시키가이샤	퀴놀린 유도체의 비정질 형태 및 그의 제조방법
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LT3263106T (lt)	2015-02-25	2024-01-10	Eisai R&D Management Co., Ltd.	Chinolino darinių kartumo sumažinimo būdas
KR102662228B1 (ko)	2015-03-04	2024-05-02	머크 샤프 앤드 돔 코포레이션	암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
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2000
- 2000-03-03 YU YU13200A patent/YU13200A/sh unknown
- 2000-03-03 RS YUP-132/00A patent/RS49836B/sr unknown
- 2000-03-10 OA OA1200000071A patent/OA11335A/en unknown
- 2000-03-14 CR CR6165A patent/CR6165A/es unknown
- 2000-03-17 PA PA20008491901A patent/PA8491901A1/es unknown
- 2000-03-20 EP EP00302256A patent/EP1044969B1/en not_active Expired - Lifetime
- 2000-03-20 PT PT00302256T patent/PT1044969E/pt unknown
- 2000-03-20 DK DK00302256T patent/DK1044969T3/da active
- 2000-03-20 AT AT00302256T patent/ATE348098T1/de not_active IP Right Cessation
- 2000-03-20 DE DE60032275T patent/DE60032275T2/de not_active Expired - Lifetime
- 2000-03-20 ES ES00302256T patent/ES2278578T3/es not_active Expired - Lifetime
- 2000-03-21 IS IS5411A patent/IS2468B/is unknown
- 2000-03-22 CO CO00020444A patent/CO5160273A1/es unknown
- 2000-03-23 IL IL168036A patent/IL168036A/en not_active IP Right Cessation
- 2000-03-23 IL IL13524500A patent/IL135245A0/xx not_active IP Right Cessation
- 2000-03-27 UA UA20040503766A patent/UA80955C2/uk unknown
- 2000-03-27 EG EG20000364A patent/EG22506A/xx active
- 2000-03-27 BR BRPI0001486A patent/BRPI0001486B8/pt not_active IP Right Cessation
- 2000-03-27 UA UA2000031727A patent/UA70928C2/uk unknown
- 2000-03-27 TW TW089105605A patent/TW553939B/zh not_active IP Right Cessation
- 2000-03-27 SK SK444-2000A patent/SK287339B6/sk not_active IP Right Cessation
- 2000-03-27 SG SG200302185A patent/SG115536A1/en unknown
- 2000-03-27 ID IDP20000240A patent/ID25427A/id unknown
- 2000-03-27 SG SG200001746A patent/SG121687A1/en unknown
- 2000-03-28 BG BG104278A patent/BG65194B1/bg unknown
- 2000-03-28 AU AU22620/00A patent/AU781402B2/en not_active Expired
- 2000-03-29 DZ DZ000059A patent/DZ3030A1/xx active
- 2000-03-29 CA CA002427221A patent/CA2427221C/en not_active Expired - Lifetime
- 2000-03-29 MA MA25940A patent/MA25087A1/fr unknown
- 2000-03-29 UY UY26086A patent/UY26086A1/es not_active Application Discontinuation
- 2000-03-29 JP JP2000091300A patent/JP3420549B2/ja not_active Expired - Lifetime
- 2000-03-29 AP APAP/P/2003/002757D patent/AP1655A/en active
- 2000-03-29 MY MYPI20001252A patent/MY136270A/en unknown
- 2000-03-29 AR ARP000101413A patent/AR018705A1/es active IP Right Grant
- 2000-03-29 ZA ZA200001586A patent/ZA200001586B/xx unknown
- 2000-03-29 CA CA002302965A patent/CA2302965C/en not_active Expired - Lifetime
- 2000-03-29 TN TNTNSN00064A patent/TNSN00064A1/fr unknown
- 2000-03-29 AP APAP/P/2000/001778A patent/AP1265A/en active
- 2000-03-30 EA EA200000274A patent/EA004654B1/ru not_active IP Right Cessation
- 2000-03-30 CZ CZ20001155A patent/CZ299426B6/cs not_active IP Right Cessation
- 2000-03-30 HU HU0001353A patent/HU227698B1/hu unknown
- 2000-03-30 KR KR1020000016386A patent/KR100430210B1/ko not_active Expired - Lifetime
- 2000-03-30 NZ NZ503683A patent/NZ503683A/en not_active IP Right Cessation
- 2000-03-30 SV SV2000000047A patent/SV2002000047A/es not_active Application Discontinuation
- 2000-03-30 TR TR2000/00837A patent/TR200000837A2/xx unknown
- 2000-03-30 US US09/538,635 patent/US6476040B1/en not_active Expired - Lifetime
- 2000-03-30 PL PL00339330A patent/PL339330A1/xx not_active Application Discontinuation
- 2000-03-30 EE EEP200000255A patent/EE04589B1/xx not_active IP Right Cessation
- 2000-03-30 GT GT200000037A patent/GT200000037A/es unknown
- 2000-03-30 NO NO20001648A patent/NO321952B1/no not_active IP Right Cessation
- 2000-03-30 EA EA200201244A patent/EA005561B1/ru not_active IP Right Cessation
- 2000-03-30 EA EA200201245A patent/EA005892B1/ru not_active IP Right Cessation
- 2000-03-30 PE PE2000000277A patent/PE20001599A1/es not_active Application Discontinuation
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- 2000-03-31 HR HR20000182A patent/HRP20000182B1/xx not_active IP Right Cessation
- 2000-03-31 CN CNB2005100763600A patent/CN100351242C/zh not_active Expired - Lifetime
- 2000-03-31 CN CNB001045954A patent/CN1215061C/zh not_active Expired - Lifetime
- 2000-03-31 GE GEAP20005284A patent/GEP20022653B/en unknown
2002
- 2002-07-29 KR KR10-2002-0044610A patent/KR100430209B1/ko not_active Expired - Lifetime
- 2002-12-12 JP JP2002360742A patent/JP4074509B2/ja not_active Expired - Lifetime
2005
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Also Published As

Publication number	Publication date
EP1044969B1 (en)	2006-12-13
AU2005201494A1 (en)	2005-05-05
KR100430209B1 (ko)	2004-05-03
SV2002000047A (es)	2002-01-23
UY26086A1 (es)	2000-10-31
PE20001599A1 (es)	2001-01-18
SG121687A1 (en)	2006-05-26
NZ503683A (en)	2001-09-28
MA25087A1 (fr)	2000-10-01
KR20010014658A (ko)	2001-02-26
NO324745B1 (no)	2007-12-03
TNSN00064A1 (fr)	2005-11-10
TR200000837A2 (tr)	2000-11-21
EA200201244A1 (ru)	2003-04-24
EG22506A (en)	2003-03-31
GEP20022653B (en)	2002-03-25
CA2302965A1 (en)	2000-09-30
NO321952B1 (no)	2006-07-24
NO20054715L (no)	2000-10-02
EA200000274A3 (ru)	2003-02-27
BRPI0001486B8 (pt)	2021-05-25
BR0001486A (pt)	2001-05-02
BG104278A (en)	2001-08-31
KR100430210B1 (ko)	2004-05-03
UA80955C2 (en)	2007-11-26
HU227698B1 (en)	2011-12-28
AP2000001778A0 (en)	2000-03-31
AU2262000A (en)	2000-10-05
PT1044969E (pt)	2007-05-31
AP1655A (en)	2006-09-01
KR20020084903A (ko)	2002-11-13
CN1276370A (zh)	2000-12-13
HUP0001353A3 (en)	2002-01-28
EP1044969A2 (en)	2000-10-18
PA8491901A1 (es)	2001-12-14
DK1044969T3 (da)	2007-04-23
IS2468B (is)	2008-12-15
JP2000290262A (ja)	2000-10-17
ID25427A (id)	2000-10-05
EA005561B1 (ru)	2005-04-28
HK1029790A1 (en)	2001-04-12
EA200201245A1 (ru)	2003-04-24
CZ20001155A3 (cs)	2001-03-14
AR018705A1 (es)	2001-11-28
CN100351242C (zh)	2007-11-28
OA11335A (en)	2003-12-10
ATE348098T1 (de)	2007-01-15
CR6165A (es)	2008-10-10
CN1699350A (zh)	2005-11-23
CA2427221C (en)	2008-09-16
DE60032275D1 (de)	2007-01-25
MY136270A (en)	2008-09-30
CA2427221A1 (en)	2000-09-30
EA200000274A2 (ru)	2000-10-30
GT200000037A (es)	2001-09-21
US6476040B1 (en)	2002-11-05
HU0001353D0 (en)	2000-06-28
BG65194B1 (bg)	2007-06-29
EE04589B1 (et)	2006-02-15
BRPI0001486B1 (pt)	2019-01-29
JP2003176274A (ja)	2003-06-24
JP3420549B2 (ja)	2003-06-23
IS5411A (is)	2000-10-02
ZA200001586B (en)	2001-10-01
EP1044969A3 (en)	2000-11-29
IL135245A0 (en)	2001-05-20
SK4442000A3 (en)	2000-10-09
YU13200A (sh)	2002-10-18
SG115536A1 (en)	2005-10-28
CA2302965C (en)	2004-02-17
NO20001648D0 (no)	2000-03-30
JP4074509B2 (ja)	2008-04-09
CZ299426B6 (cs)	2008-07-23
HRP20000182B1 (en)	2007-10-31
IL168036A (en)	2006-12-10
AP1265A (en)	2004-03-26
AU2005201494B2 (en)	2008-02-07
EA005892B1 (ru)	2005-06-30
CO5160273A1 (es)	2002-05-30
EA004654B1 (ru)	2004-06-24
ES2278578T3 (es)	2007-08-16
SK287339B6 (sk)	2010-07-07
AU781402B2 (en)	2005-05-19
NZ512818A (en)	2003-01-31
RS49836B (sr)	2008-08-07
PL339330A1 (en)	2000-10-09
DE60032275T2 (de)	2007-07-12
CN1215061C (zh)	2005-08-17
HRP20000182A2 (en)	2001-04-30
TW553939B (en)	2003-09-21
UA70928C2 (uk)	2004-11-15
HUP0001353A2 (hu)	2001-05-28
EE200000255A (et)	2000-12-15
NO20001648L (no)	2000-10-02

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