EA201400202A1 - Применение эстетрола в качестве экстренного контрацептива - Google Patents

Применение эстетрола в качестве экстренного контрацептива

Info

Publication number
EA201400202A1
EA201400202A1 EA201400202A EA201400202A EA201400202A1 EA 201400202 A1 EA201400202 A1 EA 201400202A1 EA 201400202 A EA201400202 A EA 201400202A EA 201400202 A EA201400202 A EA 201400202A EA 201400202 A1 EA201400202 A1 EA 201400202A1
Authority
EA
Eurasian Patent Office
Prior art keywords
emergency
esthetrol
contractive
application
present
Prior art date
Application number
EA201400202A
Other languages
English (en)
Other versions
EA028780B1 (ru
Inventor
Ваут Ваутерс
Герман Ян Теймен Кулинг-Беннинк
Людивин Пёти
Жан-Мишель Фуадар
Original Assignee
Эстетра С.П.Р.Л.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эстетра С.П.Р.Л. filed Critical Эстетра С.П.Р.Л.
Publication of EA201400202A1 publication Critical patent/EA201400202A1/ru
Publication of EA028780B1 publication Critical patent/EA028780B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

Настоящее изобретение относится к новому применению тетрагидроксилированных эстрогенов, таких как эстетрол (1,3,5(10)-эстратриен-3,15α,16α,17β-тетрол), а именно к способу экстренной контрацепции. Способ экстренной контрацепции в соответствии с настоящим изобретением включает пероральное введение эстетрола в однократной дозе в пределах 120 ч от полового сношения.
EA201400202A 2011-08-11 2012-08-09 Применение эстетрола в качестве экстренного контрацептива EA028780B1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161522480P 2011-08-11 2011-08-11
US61/522,480 2011-08-11
EP11177266.1 2011-08-11
EP11177266 2011-08-11
PCT/EP2012/065572 WO2013021025A1 (en) 2011-08-11 2012-08-09 Use of estetrol as emergency contraceptive

Publications (2)

Publication Number Publication Date
EA201400202A1 true EA201400202A1 (ru) 2014-06-30
EA028780B1 EA028780B1 (ru) 2017-12-29

Family

ID=47667911

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201400202A EA028780B1 (ru) 2011-08-11 2012-08-09 Применение эстетрола в качестве экстренного контрацептива

Country Status (19)

Country Link
US (3) US9579329B2 (ru)
EP (1) EP2741824B1 (ru)
AU (2) AU2012293593B2 (ru)
BR (1) BR112014003113A2 (ru)
CA (1) CA2843951C (ru)
CY (1) CY1118996T1 (ru)
DK (1) DK2741824T3 (ru)
EA (1) EA028780B1 (ru)
ES (1) ES2631359T3 (ru)
HR (1) HRP20170797T1 (ru)
HU (1) HUE033590T2 (ru)
LT (1) LT2741824T (ru)
ME (1) ME02723B (ru)
PL (1) PL2741824T3 (ru)
PT (1) PT2741824T (ru)
RS (1) RS55974B1 (ru)
SI (1) SI2741824T1 (ru)
SM (1) SMT201700310T1 (ru)
WO (1) WO2013021025A1 (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE029252T2 (en) 2011-06-01 2017-02-28 Estetra Sprl Process for the preparation of intermediates of estetrol
SG195121A1 (en) 2011-06-01 2013-12-30 Estetra S A Process for the production of estetrol intermediates
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
HRP20170797T1 (hr) * 2011-08-11 2017-08-11 Estetra S.P.R.L. Primjena estetrola kao hitnog kontraceptiva
TW201613576A (en) 2014-06-26 2016-04-16 Novartis Ag Intermittent dosing of MDM2 inhibitor
CN116077454A (zh) 2015-06-18 2023-05-09 埃斯特拉有限责任公司 含雌四醇组分的口腔分散剂量单位
RS61777B1 (sr) 2015-06-18 2021-06-30 Estetra Sprl Oralno-disperzibilna tableta koja sadrži estetrol
HUE054589T2 (hu) 2015-06-18 2021-09-28 Estetra Sprl Szájban diszpergálódó esztetrol tartalmú tabletta
MD3310333T2 (ro) 2015-06-18 2020-06-30 Estetra Sprl Unitate de dozare orodispersabilă care conține un component estetrol
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
DK3781171T3 (da) 2018-04-19 2022-05-02 Estetra Srl Sammensætninger og deres anvendelser til lindring af menopause-associerede symptomer
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
WO2022026901A2 (en) * 2020-07-30 2022-02-03 Acer Therapeutics Inc. Nk antagonists for contraception
HUP2400151A1 (hu) 2024-02-28 2025-09-28 Richter Gedeon Nyrt Ösztetrol-monohidrát kristályosítási eljárás

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2297273A1 (en) * 2000-01-26 2001-07-26 Michael D. Perelgut 3 dimensional imaging of hard structure without the use of ionizing radiation
US7871995B2 (en) * 2001-05-23 2011-01-18 Pantarhei Bioscience B.V. Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception
EP1390042B1 (en) * 2001-05-23 2007-11-28 Pantarhei Bioscience B.V. Drug delivery system comprising a tetrahydroxylated estrogen for use in hormonal contraception
HU227198B1 (en) * 2001-11-27 2010-10-28 Richter Gedeon Nyrt Pharmaceutical composition for emergency contraception containing levonorgestrel
DK1562976T3 (da) * 2002-11-08 2010-08-16 Pantarhei Bioscience Bv Syntese af estetrol via estron-afledte steroider
JP2004235111A (ja) * 2003-01-31 2004-08-19 Ebara Corp イオン伝導体及びその製造方法
HRP20170797T1 (hr) * 2011-08-11 2017-08-11 Estetra S.P.R.L. Primjena estetrola kao hitnog kontraceptiva
NO3079671T3 (ru) * 2013-12-12 2018-03-24

Also Published As

Publication number Publication date
EP2741824A1 (en) 2014-06-18
AU2012293593A8 (en) 2014-05-29
US20170196886A1 (en) 2017-07-13
US20210290636A1 (en) 2021-09-23
AU2012293593B2 (en) 2017-03-23
AU2017203991B2 (en) 2019-03-14
US9579329B2 (en) 2017-02-28
SMT201700310T1 (it) 2017-07-18
ME02723B (me) 2017-10-20
HRP20170797T1 (hr) 2017-08-11
HK1197027A1 (en) 2015-01-02
SI2741824T1 (sl) 2017-06-30
BR112014003113A2 (pt) 2017-03-14
DK2741824T3 (en) 2017-07-10
RS55974B1 (sr) 2017-09-29
AU2017203991A1 (en) 2017-07-06
HUE033590T2 (hu) 2017-12-28
EP2741824B1 (en) 2017-05-03
ES2631359T3 (es) 2017-08-30
PT2741824T (pt) 2017-07-06
WO2013021025A1 (en) 2013-02-14
LT2741824T (lt) 2017-06-26
CY1118996T1 (el) 2018-01-10
CA2843951A1 (en) 2013-02-14
US20140200202A1 (en) 2014-07-17
CA2843951C (en) 2019-08-06
AU2012293593A1 (en) 2014-03-06
PL2741824T3 (pl) 2018-03-30
EA028780B1 (ru) 2017-12-29

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