ECSP045277A - Composición oftálmica que comprende ascomicina - Google Patents
Composición oftálmica que comprende ascomicinaInfo
- Publication number
- ECSP045277A ECSP045277A EC2004005277A ECSP045277A ECSP045277A EC SP045277 A ECSP045277 A EC SP045277A EC 2004005277 A EC2004005277 A EC 2004005277A EC SP045277 A ECSP045277 A EC SP045277A EC SP045277 A ECSP045277 A EC SP045277A
- Authority
- EC
- Ecuador
- Prior art keywords
- ascomycin
- ophthalm
- composition
- blepharitis
- treatment
- Prior art date
Links
- ZDQSOHOQTUFQEM-PKUCKEGBSA-N ascomycin Chemical compound C/C([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@@H](OC)C[C@@H](C)C\C(C)=C/[C@H](C(C[C@H](O)[C@H]1C)=O)CC)=C\[C@@H]1CC[C@@H](O)[C@H](OC)C1 ZDQSOHOQTUFQEM-PKUCKEGBSA-N 0.000 title abstract 2
- ZDQSOHOQTUFQEM-XCXYXIJFSA-N ascomycin Natural products CC[C@H]1C=C(C)C[C@@H](C)C[C@@H](OC)[C@H]2O[C@@](O)([C@@H](C)C[C@H]2OC)C(=O)C(=O)N3CCCC[C@@H]3C(=O)O[C@H]([C@H](C)[C@@H](O)CC1=O)C(=C[C@@H]4CC[C@@H](O)[C@H](C4)OC)C ZDQSOHOQTUFQEM-XCXYXIJFSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000010217 blepharitis Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La invención se refiere a composiciones oftálmicas tópicas, las cuales comprenden una ascomicina, por ejemplo, para el tratamiento de enfermedades inflamatorias, tales como blefaritis.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36151502P | 2002-03-04 | 2002-03-04 | |
| US40927502P | 2002-09-09 | 2002-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP045277A true ECSP045277A (es) | 2004-10-26 |
Family
ID=27791682
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2004005277A ECSP045277A (es) | 2002-03-04 | 2004-09-03 | Composición oftálmica que comprende ascomicina |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US20050220823A1 (es) |
| EP (1) | EP1482936B1 (es) |
| JP (1) | JP4740542B2 (es) |
| KR (1) | KR100992948B1 (es) |
| CN (1) | CN1297270C (es) |
| AR (1) | AR038628A1 (es) |
| AT (1) | ATE341326T1 (es) |
| AU (1) | AU2003218679B2 (es) |
| BR (1) | BR0308184A (es) |
| CA (1) | CA2477769C (es) |
| CO (1) | CO5611133A2 (es) |
| DE (1) | DE60308836T2 (es) |
| DK (1) | DK1482936T3 (es) |
| EC (1) | ECSP045277A (es) |
| EG (1) | EG24403A (es) |
| ES (1) | ES2274214T3 (es) |
| IL (2) | IL163657A0 (es) |
| MX (1) | MXPA04008571A (es) |
| MY (1) | MY137563A (es) |
| NO (1) | NO20044092L (es) |
| NZ (1) | NZ534690A (es) |
| PE (1) | PE20030828A1 (es) |
| PL (1) | PL210870B1 (es) |
| PT (1) | PT1482936E (es) |
| RU (1) | RU2322982C2 (es) |
| TW (1) | TW200305437A (es) |
| WO (1) | WO2003074054A1 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2295647T3 (es) | 2002-07-15 | 2008-04-16 | Alcon, Inc. | Composiciones de implante farmaceuticas lipofilas, no polimeras, para uso intraocular. |
| CA2492989C (en) * | 2002-07-23 | 2012-11-20 | Novartis Ag | Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent |
| GB0307866D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Pharmaceutical composition |
| BRPI0705564B8 (pt) * | 2007-10-10 | 2021-05-25 | Embrapa Pesquisa Agropecuaria | sistema do tipo cristal líquido contínuo contendo co-solvente portador de substâncias fracamente solúveis em água, seu processo de obtenção e seus usos |
| EP2238878A1 (en) | 2009-04-09 | 2010-10-13 | Nestec S.A. | Beverage preparation device having a closing mechanism with force demultiplying means |
| US8728516B2 (en) * | 2009-04-30 | 2014-05-20 | Abbvie Inc. | Stabilized lipid formulation of apoptosis promoter |
| EP2962688B1 (en) | 2009-05-12 | 2020-06-24 | Galenica AB | Oil-in-water emulsion of mometasone and propylene glycol |
| JP5779591B2 (ja) * | 2009-12-22 | 2015-09-16 | アッヴィ・インコーポレイテッド | Abt−263カプセル剤 |
| RU2437647C2 (ru) * | 2010-02-27 | 2011-12-27 | Пшеничников Виталий Георгиевич | Фармацевтическая композиция, обладающая антибактериальным, противовирусным и противогрибковым действием |
| WO2011127151A2 (en) * | 2010-04-07 | 2011-10-13 | Allergan, Inc. | Combinations of preservatives for ophthalmic compositions |
| EP2664329A1 (de) * | 2012-05-15 | 2013-11-20 | F. Holzer GmbH | Ophthalmologisches Vehikelsystem |
| WO2014153733A1 (en) * | 2013-03-27 | 2014-10-02 | Comprehensive Drug Enterprises, Ltd. | Ophthalmic composition, method for preparing the same, and use of the same |
| US11103464B2 (en) * | 2013-11-29 | 2021-08-31 | Rohto Pharmaceutical Co., Ltd. | Aqueous composition for ophthalmological use or otolaryngological use |
| US20200237859A1 (en) | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
| US11324800B2 (en) | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
| US10606760B2 (en) * | 2017-08-23 | 2020-03-31 | Samsung Electronics Co., Ltd. | Nonvolatile memory devices and methods of controlling the same |
| EP3741367A1 (en) * | 2019-05-21 | 2020-11-25 | Premark Pharma GmbH | Treatment of ocular disease |
| TW202432089A (zh) * | 2023-01-31 | 2024-08-16 | 溫士頓醫藥股份有限公司 | 一種滴眼油劑型的醫藥組合物 |
| WO2024209038A1 (en) | 2023-04-06 | 2024-10-10 | Premark Pharma Gmbh | Use of pimecrolimus for the treatment of dry eye in patients characterized by a corneal staining score of 4 or 5 on the oxford grading scale |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU635286B2 (en) * | 1989-07-05 | 1993-03-18 | Astellas Pharma Inc. | Aqueous liquid composition for external use |
| ES2099112T3 (es) * | 1990-09-04 | 1997-05-16 | Fujisawa Pharmaceutical Co | Pomadas que contienen un compuesto triciclico. |
| PH31204A (en) * | 1990-11-02 | 1998-05-05 | Fujisawa Pharmaceutical Co | Pharmaceutical composition. |
| IE65341B1 (en) * | 1990-11-08 | 1995-10-18 | Fujisawa Pharmaceutical Co | Suspensions containing tricyclic compounds |
| AU680813B2 (en) * | 1992-08-28 | 1997-08-14 | Pharmos Corporation | Submicron emulsions as ocular drug delivery vehicles |
| JPH06345646A (ja) * | 1993-06-08 | 1994-12-20 | Fujisawa Pharmaceut Co Ltd | ローション剤 |
| CA2146006C (en) * | 1993-08-18 | 2004-10-12 | Louis Desantis, Jr. | Use of ergoline derivatives for the treatment of glaucoma |
| CA2201134A1 (en) * | 1994-10-10 | 1996-04-18 | Alfred Sallmann | Ophthalmic and aural compositions containing diclofenac potassium |
| ATE214593T1 (de) * | 1994-10-26 | 2002-04-15 | Novartis Erfind Verwalt Gmbh | Verwendung eines ungesättigten fettalkohols |
| FR2732598B1 (fr) * | 1995-04-10 | 1997-05-09 | Oreal | Utilisation de sel de metaux alcalino-terreux pour le traitement des prurits et des dysesthesies oculaires ou palpebraux |
| EP0737471A3 (fr) * | 1995-04-10 | 2000-12-06 | L'oreal | Utilisation d'un sel d'une métal alcalino-terreux comme inhibiteur de TNF-alpha dans une composition unique et composition obtenue |
| US6096785A (en) * | 1996-07-30 | 2000-08-01 | Novartis Nutrition Ag | Amino acid compositions and use thereof in treating renal dysfunction |
| FR2755852B1 (fr) * | 1996-11-15 | 1998-12-24 | Oreal | Utilisation d'un alkylether de glycerol dans une composition cosmetique et/ou dermatologique comme actif pour le traitement de la seborrhee et de l'acne |
| CA2326222C (en) * | 1998-04-27 | 2008-09-23 | Fujisawa Pharmaceutical Co., Ltd. | Medicinal compositions |
| GB9826656D0 (en) * | 1998-12-03 | 1999-01-27 | Novartis Ag | Organic compounds |
| AU777915B2 (en) * | 1999-04-30 | 2004-11-04 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
-
2003
- 2003-02-28 AR ARP030100667A patent/AR038628A1/es unknown
- 2003-02-28 PE PE2003000198A patent/PE20030828A1/es not_active Application Discontinuation
- 2003-03-02 EG EG2003030208A patent/EG24403A/xx active
- 2003-03-03 NZ NZ534690A patent/NZ534690A/en not_active IP Right Cessation
- 2003-03-03 PT PT03711914T patent/PT1482936E/pt unknown
- 2003-03-03 MX MXPA04008571A patent/MXPA04008571A/es active IP Right Grant
- 2003-03-03 MY MYPI20030758A patent/MY137563A/en unknown
- 2003-03-03 PL PL370917A patent/PL210870B1/pl not_active IP Right Cessation
- 2003-03-03 CA CA2477769A patent/CA2477769C/en not_active Expired - Fee Related
- 2003-03-03 DE DE60308836T patent/DE60308836T2/de not_active Expired - Lifetime
- 2003-03-03 EP EP03711914A patent/EP1482936B1/en not_active Expired - Lifetime
- 2003-03-03 AU AU2003218679A patent/AU2003218679B2/en not_active Ceased
- 2003-03-03 RU RU2004129593/15A patent/RU2322982C2/ru not_active IP Right Cessation
- 2003-03-03 TW TW092104405A patent/TW200305437A/zh unknown
- 2003-03-03 JP JP2003572571A patent/JP4740542B2/ja not_active Expired - Fee Related
- 2003-03-03 IL IL16365703A patent/IL163657A0/xx unknown
- 2003-03-03 CN CNB038052105A patent/CN1297270C/zh not_active Expired - Fee Related
- 2003-03-03 ES ES03711914T patent/ES2274214T3/es not_active Expired - Lifetime
- 2003-03-03 KR KR1020047013051A patent/KR100992948B1/ko not_active Expired - Fee Related
- 2003-03-03 WO PCT/EP2003/002156 patent/WO2003074054A1/en not_active Ceased
- 2003-03-03 BR BR0308184-2A patent/BR0308184A/pt not_active IP Right Cessation
- 2003-03-03 AT AT03711914T patent/ATE341326T1/de active
- 2003-03-03 DK DK03711914T patent/DK1482936T3/da active
- 2003-03-03 US US10/506,233 patent/US20050220823A1/en not_active Abandoned
-
2004
- 2004-08-19 IL IL163657A patent/IL163657A/en not_active IP Right Cessation
- 2004-09-03 EC EC2004005277A patent/ECSP045277A/es unknown
- 2004-09-16 CO CO04092300A patent/CO5611133A2/es not_active Application Discontinuation
- 2004-09-27 NO NO20044092A patent/NO20044092L/no not_active Application Discontinuation
-
2009
- 2009-12-15 US US12/638,313 patent/US20100113501A1/en not_active Abandoned
-
2011
- 2011-03-01 US US13/037,399 patent/US20110152307A1/en not_active Abandoned
- 2011-09-23 US US13/241,340 patent/US20120015971A1/en not_active Abandoned
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