ECSP056071A - Nueva difenilazetidinona con características fisiológicas mejoradas, correspondiente método de producción, medicamentos que contienen dicho compuesto y su uso - Google Patents

Nueva difenilazetidinona con características fisiológicas mejoradas, correspondiente método de producción, medicamentos que contienen dicho compuesto y su uso

Info

Publication number
ECSP056071A
ECSP056071A EC2005006071A ECSP056071A ECSP056071A EC SP056071 A ECSP056071 A EC SP056071A EC 2005006071 A EC2005006071 A EC 2005006071A EC SP056071 A ECSP056071 A EC SP056071A EC SP056071 A ECSP056071 A EC SP056071A
Authority
EC
Ecuador
Prior art keywords
compound
new
difenilazetidinona
production method
corresponding production
Prior art date
Application number
EC2005006071A
Other languages
English (en)
Inventor
Wendelin Frick
Hubert Heuer
Werner Kramer
Gerhard Jaehne
Andreas Lindenschmidt
Stefanie Flohr
Hans-Ludwig Schaefer
Eric Galia
Heiner Glombick
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ECSP056071A publication Critical patent/ECSP056071A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La invención se refiere a una nueva difenilazetidinona, a un método para su producción, a medicamentos que contienen dicho compuesto y a su uso. La invención se refiere al compuesto de la fórmula generL (i) además de a sus sales fisiológicamente compatibles. Dicho compuesto es adecuado, para uso, por ejemplo, como hipolipidemiante.
EC2005006071A 2003-04-01 2005-09-30 Nueva difenilazetidinona con características fisiológicas mejoradas, correspondiente método de producción, medicamentos que contienen dicho compuesto y su uso ECSP056071A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10314610A DE10314610A1 (de) 2003-04-01 2003-04-01 Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung

Publications (1)

Publication Number Publication Date
ECSP056071A true ECSP056071A (es) 2006-01-27

Family

ID=33103147

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005006071A ECSP056071A (es) 2003-04-01 2005-09-30 Nueva difenilazetidinona con características fisiológicas mejoradas, correspondiente método de producción, medicamentos que contienen dicho compuesto y su uso

Country Status (43)

Country Link
US (2) US7205290B2 (es)
EP (2) EP1613589B1 (es)
JP (1) JP2006522040A (es)
KR (1) KR20050119180A (es)
CN (2) CN100361970C (es)
AR (1) AR043783A1 (es)
AT (2) ATE386020T1 (es)
AU (1) AU2004226287B2 (es)
BR (1) BRPI0408920A (es)
CA (1) CA2520689A1 (es)
CL (1) CL43489B (es)
CR (1) CR7995A (es)
CY (2) CY1107398T1 (es)
DE (3) DE10314610A1 (es)
DK (2) DK1862455T3 (es)
EC (1) ECSP056071A (es)
ES (2) ES2322876T3 (es)
GT (1) GT200400058A (es)
HN (1) HN2004000109A (es)
HR (1) HRP20050870A2 (es)
JO (1) JO2493B1 (es)
MA (1) MA27753A1 (es)
ME (1) MEP41408A (es)
MX (1) MXPA05010128A (es)
MY (1) MY136269A (es)
NI (1) NI200500164A (es)
NO (1) NO20055001L (es)
NZ (1) NZ542751A (es)
PA (1) PA8599401A1 (es)
PE (1) PE20050011A1 (es)
PL (2) PL1862455T3 (es)
PT (2) PT1862455E (es)
RS (1) RS51146B (es)
RU (1) RU2334737C2 (es)
SA (1) SA04250154B1 (es)
SI (2) SI1862455T1 (es)
SV (1) SV2004001756A (es)
TN (1) TNSN05244A1 (es)
TW (1) TW200504009A (es)
UA (1) UA80754C2 (es)
UY (1) UY28253A1 (es)
WO (1) WO2004087655A1 (es)
ZA (1) ZA200506708B (es)

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US20080319218A1 (en) * 2007-06-22 2008-12-25 Andreas Haubrich Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate
US20080319221A1 (en) * 2007-06-22 2008-12-25 Bernd Junker Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids
DE102007029612A1 (de) * 2007-06-27 2009-01-08 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Pentahydroxyhexylcarbamoylundekan- säurebenzylester
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
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US8809325B2 (en) 2011-03-08 2014-08-19 Sanofi Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683703B1 (de) 2011-03-08 2015-05-27 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683702B1 (de) 2011-03-08 2014-12-24 Sanofi Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
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Also Published As

Publication number Publication date
CA2520689A1 (en) 2004-10-14
RU2334737C2 (ru) 2008-09-27
ES2322876T3 (es) 2009-06-30
EP1613589A1 (de) 2006-01-11
SV2004001756A (es) 2004-11-18
GT200400058A (es) 2004-11-10
CR7995A (es) 2006-09-22
HRP20050870A2 (en) 2006-10-31
CY1109055T1 (el) 2014-07-02
NZ542751A (en) 2007-05-31
MEP41408A (en) 2011-02-10
SI1613589T1 (sl) 2008-06-30
DE502004006195D1 (de) 2008-03-27
UY28253A1 (es) 2004-11-08
ZA200506708B (en) 2007-01-31
PT1613589E (pt) 2008-03-27
ATE386020T1 (de) 2008-03-15
CN1768034A (zh) 2006-05-03
AU2004226287B2 (en) 2010-03-18
PL1862455T3 (pl) 2009-07-31
PA8599401A1 (es) 2004-10-08
CN100361970C (zh) 2008-01-16
DK1862455T3 (da) 2009-06-02
BRPI0408920A (pt) 2006-03-28
SA04250154B1 (ar) 2007-10-29
JP2006522040A (ja) 2006-09-28
NI200500164A (es) 2006-01-11
US20050020563A1 (en) 2005-01-27
ES2298731T3 (es) 2008-05-16
US7772429B2 (en) 2010-08-10
ATE423766T1 (de) 2009-03-15
TNSN05244A1 (en) 2007-06-11
JO2493B1 (en) 2009-10-05
UA80754C2 (en) 2007-10-25
TW200504009A (en) 2005-02-01
EP1862455B1 (de) 2009-02-25
WO2004087655A1 (de) 2004-10-14
MXPA05010128A (es) 2005-11-16
EP1613589B1 (de) 2008-02-13
US7205290B2 (en) 2007-04-17
DK1613589T3 (da) 2008-06-09
PL1613589T3 (pl) 2008-07-31
EP1862455A2 (de) 2007-12-05
KR20050119180A (ko) 2005-12-20
US20070197498A1 (en) 2007-08-23
CL43489B (es) 2005-01-21
MA27753A1 (fr) 2006-02-01
MY136269A (en) 2008-09-30
EP1862455A3 (de) 2007-12-12
RS51146B (sr) 2010-10-31
SI1862455T1 (sl) 2009-06-30
RS20050719A (sr) 2008-04-04
HK1087697A1 (zh) 2006-10-20
DE10314610A1 (de) 2004-11-04
RU2005133631A (ru) 2006-03-10
HN2004000109A (es) 2008-02-21
PE20050011A1 (es) 2005-02-28
CY1107398T1 (el) 2012-12-19
DE502004009059D1 (de) 2009-04-09
AU2004226287A1 (en) 2004-10-14
AR043783A1 (es) 2005-08-10
NO20055001L (no) 2005-10-27
PT1862455E (pt) 2009-04-23
CN101139306A (zh) 2008-03-12

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