ECSP066689A - Forma de administración transdérmica, líquida o semisólida que contiene sustancia activa sensible a la luz, estable a los rayos ultravioletas - Google Patents

Forma de administración transdérmica, líquida o semisólida que contiene sustancia activa sensible a la luz, estable a los rayos ultravioletas

Info

Publication number
ECSP066689A
ECSP066689A EC2006006689A ECSP066689A ECSP066689A EC SP066689 A ECSP066689 A EC SP066689A EC 2006006689 A EC2006006689 A EC 2006006689A EC SP066689 A ECSP066689 A EC SP066689A EC SP066689 A ECSP066689 A EC SP066689A
Authority
EC
Ecuador
Prior art keywords
light
administration
transdermal
active substance
semisolid
Prior art date
Application number
EC2006006689A
Other languages
English (en)
Inventor
Hans-Peter Podhaisky
Stefan Bracht
Original Assignee
Schering Akti Engesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34486168&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP066689(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Akti Engesellschaft filed Critical Schering Akti Engesellschaft
Publication of ECSP066689A publication Critical patent/ECSP066689A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

La invención se refiere a formas de administración farmacéuticas semisólidas o líquidas para uso transdérmico que contiene una sustancia activa sensible a la luz UV y por lo menos una sustancia auxiliar (absorbedor de luz UV) que se encuentra presente en la forma de administración en forma disuelta o dispersa. Preferentemente, la forma de administración de la invención es un gel transdérmico, cuya base está formada por agua, alcohol, por lo menos un polímero formador de gel y si fuera necesario, otros componentes. Tales geles también se denominan geles hidroalcohólicos. La invención provee una forma de administración que comprende una sustancia activa farmacéutica sensible a la luz, cuyo sistema de aplicación tiene elevada estabilidad y no presenta las desventajas conocidas que se presentan cuando se aplican formas de administración transdérmicas semisólidas convencionales. En esta forma de administración se minimizan los efectos secundarios dañinos, como p.ej. la absorción de sustancias protectoras de la luz por el cuerpo, que pueden resultar potencialmente de medidas intencionales de protección de la luz.
EC2006006689A 2003-12-10 2006-07-07 Forma de administración transdérmica, líquida o semisólida que contiene sustancia activa sensible a la luz, estable a los rayos ultravioletas ECSP066689A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03028353A EP1541136A1 (de) 2003-12-10 2003-12-10 UV-Licht stabile halbfeste transdermale Systeme, die einen lichtempfindlichen Wirkstoff und einen UV-Absorber enthalten

Publications (1)

Publication Number Publication Date
ECSP066689A true ECSP066689A (es) 2006-10-31

Family

ID=34486168

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006689A ECSP066689A (es) 2003-12-10 2006-07-07 Forma de administración transdérmica, líquida o semisólida que contiene sustancia activa sensible a la luz, estable a los rayos ultravioletas

Country Status (24)

Country Link
EP (2) EP1541136A1 (es)
JP (1) JP2007534643A (es)
KR (1) KR20060096512A (es)
CN (1) CN101415402A (es)
AR (1) AR047140A1 (es)
AU (1) AU2004296539B2 (es)
BR (1) BRPI0416979A (es)
CA (1) CA2548739C (es)
CR (1) CR8461A (es)
EA (1) EA010239B1 (es)
EC (1) ECSP066689A (es)
GT (1) GT200400261A (es)
HN (1) HN2004000525A (es)
IL (1) IL176208A0 (es)
MX (1) MXPA06006534A (es)
MY (1) MY141728A (es)
NO (1) NO20063208L (es)
NZ (1) NZ547733A (es)
PE (1) PE20050863A1 (es)
SV (1) SV2006001971A (es)
TW (1) TW200528136A (es)
UA (1) UA85861C2 (es)
WO (1) WO2005055975A2 (es)
ZA (1) ZA200605632B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI395806B (zh) 2010-04-14 2013-05-11 Ind Tech Res Inst 封裝材料
WO2012031999A2 (en) * 2010-09-06 2012-03-15 Bayer Pharma Aktiengesellschaft Low-dose transdermal patches with high drug release
US10293023B2 (en) 2013-03-15 2019-05-21 Children's Medical Center Corporation Method of altering vascular permeability and uses thereof
JP2024000555A (ja) * 2022-06-21 2024-01-09 東ソー株式会社 紫外線抑制下でのエストラジオール測定試薬の製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60155111A (ja) * 1983-10-20 1985-08-15 Hisamitsu Pharmaceut Co Inc 安定なケトプロフェン含有外用経皮製剤
JP2981523B2 (ja) * 1990-11-19 1999-11-22 株式会社林原生物化学研究所 皮膚外用剤
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
ES2297892T3 (es) * 1997-08-21 2008-05-01 JOHNSON & JOHNSON CONSUMER COMPANIES, INC. Utilizacion de 17-beta-estradiol para el tratamiento de las pieles envejecidas o dañadas por el sol y/o atrofia de la piel.
JP2000292428A (ja) * 1999-04-05 2000-10-20 Umeda Jimusho:Kk 環境化学物質の内分泌攪乱活性の新規測定方法及びその装置
JP2001129566A (ja) * 1999-11-05 2001-05-15 Mitsubishi Heavy Ind Ltd 有害物質処理方法およびその装置
FR2804024B1 (fr) * 2000-01-21 2002-09-13 Menarini France Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation
DE10053375C1 (de) * 2000-10-27 2002-01-24 Lohmann Therapie Syst Lts Transdermale therapeutische Systeme mit lichtempfindlichen Wirkstoffen
FR2834895B1 (fr) * 2002-01-22 2006-06-23 Ellipse Pharmaceuticals Compositions dermatologiques, resistantes a l'eau, avec filtres solaires, procede de fabrication et utilisations de ces compositions
ITFI20020144A1 (it) * 2002-08-01 2004-02-02 Menarini Farma Ind Formulazioni topiche stabilizzate contenenti ketoprofene.

Also Published As

Publication number Publication date
AR047140A1 (es) 2006-01-11
TW200528136A (en) 2005-09-01
WO2005055975A2 (de) 2005-06-23
ZA200605632B (en) 2008-06-25
CA2548739A1 (en) 2005-06-23
WO2005055975A3 (de) 2009-03-12
MY141728A (en) 2010-06-15
CA2548739C (en) 2009-08-18
AU2004296539A1 (en) 2005-06-23
IL176208A0 (en) 2006-10-05
EP1703892A2 (de) 2006-09-27
UA85861C2 (uk) 2009-03-10
NO20063208L (no) 2006-07-10
BRPI0416979A (pt) 2007-02-21
GT200400261A (es) 2005-10-31
MXPA06006534A (es) 2006-08-01
CN101415402A (zh) 2009-04-22
HN2004000525A (es) 2010-09-17
EA010239B1 (ru) 2008-06-30
PE20050863A1 (es) 2005-11-02
NZ547733A (en) 2010-02-26
AU2004296539B2 (en) 2008-10-09
KR20060096512A (ko) 2006-09-11
EA200601084A1 (ru) 2006-12-29
JP2007534643A (ja) 2007-11-29
EP1541136A1 (de) 2005-06-15
CR8461A (es) 2006-12-07
SV2006001971A (es) 2006-02-15

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