ECSP066938A - Composición farmacéutica que comprende una sal de mirtazapina - Google Patents

Composición farmacéutica que comprende una sal de mirtazapina

Info

Publication number
ECSP066938A
ECSP066938A EC2006006938A ECSP066938A ECSP066938A EC SP066938 A ECSP066938 A EC SP066938A EC 2006006938 A EC2006006938 A EC 2006006938A EC SP066938 A ECSP066938 A EC SP066938A EC SP066938 A ECSP066938 A EC SP066938A
Authority
EC
Ecuador
Prior art keywords
salt
mirtazapine
pharmaceutical composition
mirtazapine salt
acid
Prior art date
Application number
EC2006006938A
Other languages
English (en)
Inventor
Gerardus Johnnes Kemperman
Sytske Hyke Moolenaar
Der Voort Maarschalk Kees Van
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of ECSP066938A publication Critical patent/ECSP066938A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invención provee una sal no sublimante y sólida farmacéuticamente aceptable de un enantiómero de mirtazapina, especialmente una sal de mirtazapina seleccionada entre el grupo conformado por sal de ácido maleico, ácido hidrobrómico y ácido fumárico, para uso en la fabricación de una composición farmacéutica que comprende una sal de mirtazapina S o R.
EC2006006938A 2004-04-21 2006-10-19 Composición farmacéutica que comprende una sal de mirtazapina ECSP066938A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04101664 2004-04-21

Publications (1)

Publication Number Publication Date
ECSP066938A true ECSP066938A (es) 2006-12-20

Family

ID=34928990

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006938A ECSP066938A (es) 2004-04-21 2006-10-19 Composición farmacéutica que comprende una sal de mirtazapina

Country Status (31)

Country Link
US (1) US20070111993A1 (es)
EP (1) EP1729777B1 (es)
JP (2) JP5260959B2 (es)
CN (2) CN101824035A (es)
AR (1) AR049028A1 (es)
AT (1) ATE424210T1 (es)
AU (1) AU2005235383B2 (es)
BR (1) BRPI0509953A (es)
CA (1) CA2561281C (es)
CY (1) CY1109018T1 (es)
DE (1) DE602005013066D1 (es)
DK (1) DK1729777T3 (es)
EC (1) ECSP066938A (es)
ES (1) ES2321961T3 (es)
HR (1) HRP20090190T1 (es)
IL (1) IL178201A (es)
LV (1) LV13556B (es)
MX (1) MXPA06011830A (es)
MY (1) MY144899A (es)
NO (1) NO20065077L (es)
NZ (1) NZ550052A (es)
PE (1) PE20060400A1 (es)
PL (1) PL1729777T3 (es)
PT (1) PT1729777E (es)
RS (1) RS50764B (es)
RU (1) RU2375362C2 (es)
SI (1) SI1729777T1 (es)
TW (1) TW200538100A (es)
UA (1) UA89773C2 (es)
WO (1) WO2005102352A1 (es)
ZA (1) ZA200608305B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA83666C2 (ru) * 2003-07-10 2008-08-11 Н.В. Органон Способ получения энантиомерно чистого миртазапина
EP1792618A1 (en) * 2005-11-30 2007-06-06 Rainer Freynhagen R-mirtazapine for the treatment of pain
TW200808804A (en) * 2006-05-22 2008-02-16 Organon Nv Mirtazapine for the treatment of neuropathic pain
CN104095824B (zh) * 2013-04-09 2016-08-31 上海信谊万象药业股份有限公司 一种米氮平缓释片及其制备方法
WO2016138357A1 (en) 2015-02-27 2016-09-01 Kindred Biosciences, Inc. Stimulation of appetite, management of weight loss, and treatment of anorexia in dogs and cats
CN111053735A (zh) * 2020-02-25 2020-04-24 上海阶平医院管理有限公司 一种治疗失眠的冷敷凝胶

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189199C (nl) * 1975-04-05 1993-02-01 Akzo Nv Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
US4193828A (en) * 1976-07-27 1980-03-18 Fiber Materials, Inc. Method of forming carbon composites
US4515792A (en) * 1982-09-30 1985-05-07 Ciba-Geigy Corporation Tetracyclic heterocycles and antidepressant compositions thereof
EP0813873B1 (en) * 1996-06-19 2002-02-13 Akzo Nobel N.V. Pharmaceutical composition comprising mirtazapine and one or more selective serotonin reuptake inhibitors
IL121076A (en) * 1996-06-19 2000-10-31 Akzo Nobel Nv Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors
DE69913116T2 (de) * 1998-04-02 2004-06-03 Akzo Nobel N.V. Orale flüssige lösung enthaltend das antidepressivum mirtazapine
AU5764900A (en) * 1999-06-25 2001-01-31 University Of South Florida Mirtazapine for weight gain in wasting diseases
US6281207B1 (en) * 1999-09-15 2001-08-28 Reed Richter Treatment of movement disorders by administration of mirtazapine
AU6474200A (en) * 1999-12-13 2001-06-18 Sumika Fine Chemicals Co., Ltd. Process for the preparation of a pyridinemethanol compound
NZ521631A (en) * 2000-04-05 2005-01-28 Akzo Nobel Nv Drug combination for the treatment of headache comprising a non-steroidal anti-inflammatory drug

Also Published As

Publication number Publication date
UA89773C2 (ru) 2010-03-10
AU2005235383A1 (en) 2005-11-03
TW200538100A (en) 2005-12-01
CN1942191B (zh) 2011-02-02
JP5260959B2 (ja) 2013-08-14
AR049028A1 (es) 2006-06-21
MXPA06011830A (es) 2007-03-23
DK1729777T3 (da) 2009-06-08
EP1729777B1 (en) 2009-03-04
SI1729777T1 (sl) 2009-08-31
ZA200608305B (en) 2008-08-27
IL178201A0 (en) 2006-12-31
ES2321961T3 (es) 2009-06-15
RS50764B (sr) 2010-08-31
LV13556B (en) 2007-07-20
RU2375362C2 (ru) 2009-12-10
CN1942191A (zh) 2007-04-04
PT1729777E (pt) 2009-04-27
US20070111993A1 (en) 2007-05-17
HRP20090190T1 (en) 2009-05-31
CY1109018T1 (el) 2014-07-02
IL178201A (en) 2010-06-30
EP1729777A1 (en) 2006-12-13
PL1729777T3 (pl) 2009-07-31
AU2005235383B2 (en) 2010-05-27
ATE424210T1 (de) 2009-03-15
RU2006140988A (ru) 2008-05-27
DE602005013066D1 (de) 2009-04-16
CA2561281A1 (en) 2005-11-03
MY144899A (en) 2011-11-30
JP2013136626A (ja) 2013-07-11
PE20060400A1 (es) 2006-05-27
NZ550052A (en) 2010-02-26
CN101824035A (zh) 2010-09-08
CA2561281C (en) 2013-04-02
WO2005102352A1 (en) 2005-11-03
NO20065077L (no) 2006-11-14
BRPI0509953A (pt) 2007-09-25
JP2007533705A (ja) 2007-11-22

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