ECSP099648A - Derivados de aril isoxazolina insecticidas - Google Patents

Derivados de aril isoxazolina insecticidas

Info

Publication number
ECSP099648A
ECSP099648A EC2009009648A ECSP099648A ECSP099648A EC SP099648 A ECSP099648 A EC SP099648A EC 2009009648 A EC2009009648 A EC 2009009648A EC SP099648 A ECSP099648 A EC SP099648A EC SP099648 A ECSP099648 A EC SP099648A
Authority
EC
Ecuador
Prior art keywords
insecticided
aril
isoxazoline derivatives
insecticides
derivatives
Prior art date
Application number
EC2009009648A
Other languages
English (en)
Inventor
Jun Mihara
Daiei Yamazaki
Katsuhiko Shibuya
Eiichi Shimojo
Tetsuya Murata
Andreas Turberg
Yasushi Yoneta
Ulrich Goergens
Thomas Bach
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2007102395A external-priority patent/JP2008260691A/ja
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of ECSP099648A publication Critical patent/ECSP099648A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a nuevos derivados de aril isoxazolina que tienen una excelente actividad insecticida como insecticidas y se representan por la fórmula (I); y a su uso como insecticidas y acaricidas.
EC2009009648A 2007-04-10 2009-09-23 Derivados de aril isoxazolina insecticidas ECSP099648A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007102395A JP2008260691A (ja) 2007-04-10 2007-04-10 殺虫性アリールイソオキサゾリン誘導体
EP07123793 2007-12-20

Publications (1)

Publication Number Publication Date
ECSP099648A true ECSP099648A (es) 2009-10-30

Family

ID=39712319

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009648A ECSP099648A (es) 2007-04-10 2009-09-23 Derivados de aril isoxazolina insecticidas

Country Status (24)

Country Link
US (1) US8372867B2 (es)
EP (1) EP2181100A2 (es)
JP (1) JP5548119B2 (es)
KR (1) KR20090130064A (es)
AR (1) AR065985A1 (es)
AU (1) AU2008235089B8 (es)
BR (1) BRPI0810196A2 (es)
CA (1) CA2683180A1 (es)
CL (1) CL2008000962A1 (es)
CO (1) CO6231032A2 (es)
CR (1) CR11038A (es)
DO (1) DOP2009000227A (es)
EC (1) ECSP099648A (es)
IL (1) IL200634A0 (es)
MX (1) MX2009010071A (es)
MY (1) MY146638A (es)
NZ (1) NZ580241A (es)
PE (1) PE20090800A1 (es)
RU (1) RU2009141185A (es)
SV (1) SV2009003376A (es)
TW (1) TW200847925A (es)
UY (1) UY30992A1 (es)
WO (1) WO2008122375A2 (es)
ZA (1) ZA200907045B (es)

Families Citing this family (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005219788B2 (en) 2004-03-05 2010-06-03 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and noxious organism control agent
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
BRPI0707091B8 (pt) 2006-03-10 2018-02-14 Nissan Chemical Ind Ltd composto de isoxalina e benzaldoxima substituído ou um sal do mesmo; pesticida, agroquímico, endo- ou ecto-parasiticidapara mamíferos ou pássaros, inseticida e acaricida contendo como um ou mais ingredientes ativos selecionados a partir do composto de isoxalina substituído e o sal do mesmo
AU2008261793A1 (en) 2007-06-13 2008-12-18 E. I. Du Pont De Nemours And Company Isoxazoline insecticides
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
ES2549731T3 (es) 2007-06-27 2015-11-02 E. I. Du Pont De Nemours And Company Método para el control de plagas en animales
TWI649303B (zh) * 2007-08-17 2019-02-01 杜邦股份有限公司 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
CN101801940B (zh) 2007-09-10 2013-04-10 日产化学工业株式会社 取代异*唑啉化合物和有害生物防除剂
US8367584B2 (en) 2007-10-03 2013-02-05 E.I. Du Pont De Nemours And Company Naphthalene isoxazoline compounds for control of invertebrate pests
WO2009072621A1 (ja) * 2007-12-07 2009-06-11 Nissan Chemical Industries, Ltd. 置換ジヒドロアゾール化合物及び有害生物防除剤
ES2530064T3 (es) * 2008-02-07 2015-02-26 Bayer Cropscience Ag Arilpirrolinas insecticidas
TWI518076B (zh) 2008-04-09 2016-01-21 杜邦股份有限公司 製備雜環化合物之方法
CN102088856B (zh) 2008-07-09 2015-11-25 巴斯夫欧洲公司 包含异*唑啉化合物的杀虫活性混合物i
CN102088857A (zh) * 2008-07-09 2011-06-08 巴斯夫欧洲公司 包含异噁唑啉化合物的杀虫活性混合物ⅱ
CA2737291C (en) * 2008-09-18 2013-04-16 Nippon Soda Co., Ltd. Nitrogen-containing heterocyclic compound and pest control agent
MY153715A (en) 2008-11-14 2015-03-13 Merial Ltd Enantiomerically enriched aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
ES2781828T3 (es) 2008-11-19 2020-09-08 Boehringer Ingelheim Animal Health Usa Inc Composiciones que comprenden un aril pirazol y/o una formamidina, procedimientos y usos de las mismas
JP5595412B2 (ja) 2008-12-04 2014-09-24 メリアル リミテッド 二量体アベルメクチン及びミルベマイシン誘導体
ES2921576T3 (es) 2008-12-19 2022-08-29 Vertex Pharma Compuestos útiles como inhibidores de la quinasa ATR
CA2747986A1 (en) 2008-12-23 2010-07-01 Basf Se Substituted amidine compounds for combating animal pests
TW201029997A (en) 2008-12-23 2010-08-16 Basf Se Imine compounds for combating invertebrate pests
CN102365278B (zh) * 2009-03-26 2015-05-06 先正达参股股份有限公司 杀虫化合物
EP2414353A1 (en) * 2009-04-01 2012-02-08 Basf Se Isoxazoline compounds for combating invertebrate pests
ES2524970T3 (es) 2009-04-30 2014-12-16 Basf Se Procedimiento de preparación de compuestos de isoxazolina sustituidos y sus precursores
ES2536278T3 (es) * 2009-05-19 2015-05-22 Bayer Intellectual Property Gmbh Arilpirrolinas insecticidas
CN102725286A (zh) * 2009-11-06 2012-10-10 拜耳作物科学公司 杀虫用芳基吡咯啉化合物
TWI487486B (zh) 2009-12-01 2015-06-11 Syngenta Participations Ag 以異唑啉衍生物為主之殺蟲化合物
EP3078664B1 (en) 2009-12-17 2019-02-20 Merial Inc. Antiparasitic dihydroazole compositions
JP2011136928A (ja) 2009-12-28 2011-07-14 Bayer Cropscience Ag 殺虫性アリールピロリジン類
JP2013518084A (ja) 2010-02-01 2013-05-20 ビーエーエスエフ ソシエタス・ヨーロピア 有害動物を駆除するための置換されたケトン性イソオキサゾリン化合物および誘導体
CN102741252A (zh) 2010-02-05 2012-10-17 英特维特国际股份有限公司 用作驱虫剂的螺吲哚啉化合物
BR112012020521B1 (pt) 2010-02-17 2017-12-26 Syngenta Participations Ag Derivative compounds of isoxazoline, its intermediaries and method for controlling insects, mites, nematodes, or molluscs
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
MX2012011549A (es) 2010-04-08 2013-01-29 Ah Usa 42 Llc Derivados de 3,5-difenil-isoxazolina sustituida como insecticidas y acaricidas.
EP2568984A1 (en) 2010-05-12 2013-03-20 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of atr kinase
US8962631B2 (en) 2010-05-12 2015-02-24 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
CA2798760A1 (en) 2010-05-12 2011-11-17 Vertex Pharmaceuticals Incorporated 2-aminopyridine derivatives useful as inhibitors of atr kinase
US9062008B2 (en) 2010-05-12 2015-06-23 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
US9334244B2 (en) 2010-05-12 2016-05-10 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
NZ603477A (en) 2010-05-12 2014-09-26 Vertex Pharma Compounds useful as inhibitors of atr kinase
RS54677B1 (sr) 2010-05-27 2016-08-31 E. I. Du Pont De Nemours And Company Kristalni oblici 4-[5-[3-hloro-5-(trifluorometil)fenil]-4,5 -dihidro-5-(trifluorometil)-3-izoksazolil]-n-[2-okso-2-[(2,2,2-trifluoroetil)amino]etil]-1-naftalenkarboksamida
MX2013000103A (es) 2010-06-23 2013-06-13 Vertex Pharma Derivados de pirrolo-pirazina utiles como inhibidores de cinasa art.
JP2013532156A (ja) * 2010-06-23 2013-08-15 ビーエーエスエフ ソシエタス・ヨーロピア 無脊椎有害生物を駆除するためのイミン化合物を製造するための方法
WO2012007365A1 (en) * 2010-07-12 2012-01-19 F. Hoffmann-La Roche Ag 1-hydroxyimino-3-phenyl-propanes
WO2012007426A1 (en) 2010-07-13 2012-01-19 Basf Se Azoline substituted isoxazoline benzamide compounds for combating animal pests
ES2682303T3 (es) 2010-08-05 2018-09-19 Zoetis Services Llc Derivados de isoxazolina como agentes antiparasitarios
CN103189356B (zh) 2010-09-29 2015-11-25 英特维特国际股份有限公司 N-杂芳基化合物
US8883791B2 (en) 2010-09-29 2014-11-11 Intervet Inc. N-heteroaryl compounds with cyclic bridging unit for the treatment of parasitic diseases
KR20130143047A (ko) 2010-10-01 2013-12-30 바스프 에스이 살충제로서의 이민 치환된 2,4-디아릴-피롤린 유도체
CN103237789A (zh) 2010-10-01 2013-08-07 巴斯夫欧洲公司 亚胺化合物
EP2635552A2 (en) 2010-11-03 2013-09-11 Basf Se Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes
UY33887A (es) 2011-02-03 2012-09-28 Syngenta Ltd Métodos de control de plagas en la soja
PH12013501831B1 (en) 2011-03-10 2019-06-14 Zoetis Services Llc Spirocyclic isoxazoline derivatives as antiparasitic agents
WO2012120135A1 (en) * 2011-03-10 2012-09-13 Novartis Ag Isoxazole derivatives
MX2013011450A (es) 2011-04-05 2014-02-03 Vertex Pharma Compuestos de aminopirazina utiles como inhibidores de la cinasa ataxia telangiectasia mutada y rad3 relacionados (atr).
WO2012156400A1 (en) * 2011-05-18 2012-11-22 Syngenta Participations Ag Insecticidal compounds based on arylthioacetamide derivatives
WO2012155352A1 (en) 2011-05-19 2012-11-22 Eli Lilly And Company Dihydroisoxazole compounds, parasiticidal uses and formulations thereof
BR112013030570A2 (pt) * 2011-05-31 2016-08-16 Sumitomo Chemical Co agente para o controle de ectoparasitas de animais
US8822469B2 (en) 2011-06-22 2014-09-02 Vertex Pharmaceuticals Incorporated Pyrrolo[2,3-B]pyrazines useful as inhibitors of ATR kinase
US9309250B2 (en) 2011-06-22 2016-04-12 Vertex Pharmaceuticals Incorporated Substituted pyrrolo[2,3-b]pyrazines as ATR kinase inhibitors
EP2723747A1 (en) 2011-06-22 2014-04-30 Vertex Pharmaceuticals Inc. Compounds useful as inhibitors of atr kinase
ES2618813T3 (es) 2011-06-27 2017-06-22 Merial, Inc. Compuestos y composiciones de éter amido-piridílico y uso contra los parásitos
US9096599B2 (en) 2011-08-04 2015-08-04 Intervet Inc. Spiroindoline compounds
WO2013026939A1 (en) 2011-08-25 2013-02-28 Syngenta Participations Ag Methods for the control of termites and ants
PL3172964T3 (pl) 2011-09-12 2021-03-08 Boehringer Ingelheim Animal Health USA Inc. Kompozycje przeciwpasożytniczne zawierające izoksazolinową substancję czynną, sposób i ich zastosowania
WO2013049722A1 (en) 2011-09-30 2013-04-04 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of atr kinase
WO2013049720A1 (en) 2011-09-30 2013-04-04 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of atr kinase
CN108685922A (zh) 2011-09-30 2018-10-23 沃泰克斯药物股份有限公司 用atr抑制剂治疗胰腺癌和非小细胞肺癌
US8765751B2 (en) 2011-09-30 2014-07-01 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
CN106496173A (zh) 2011-09-30 2017-03-15 沃泰克斯药物股份有限公司 用于制备可用作atr激酶抑制剂的化合物的方法
JP2015502925A (ja) 2011-11-09 2015-01-29 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ａｔｒキナーゼの阻害剤として有用なピラジン化合物
US8846918B2 (en) 2011-11-09 2014-09-30 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
US8841337B2 (en) 2011-11-09 2014-09-23 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
US8846917B2 (en) 2011-11-09 2014-09-30 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
US8841450B2 (en) 2011-11-09 2014-09-23 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
CN104023720B (zh) 2011-11-17 2016-10-26 梅里亚有限公司 包含芳基吡唑和取代咪唑的组合物，其方法和用途
EP3351546B9 (en) 2011-12-02 2024-07-10 Boehringer Ingelheim Vetmedica GmbH Long-acting injectable moxidectin formulations
WO2013092943A1 (en) 2011-12-23 2013-06-27 Basf Se Isothiazoline compounds for combating invertebrate pests
WO2013116230A1 (en) 2012-02-03 2013-08-08 Zoetis Llc Dihydrofuran azetidine derivatives as antiparasitic agents
LT2811998T (lt) 2012-02-06 2019-02-25 Merial, Inc. Paraziticidinės peroralinės veterinarinės kompozicijos, apimančios sistemiškai veikiančius aktyviuosius agentus, būdai ir jų panaudojimas
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
AU2013241853B2 (en) 2012-03-28 2017-11-09 Intervet International B.V. Heteroaryl compounds with A-cyclic bridging unit
WO2013144180A1 (en) 2012-03-28 2013-10-03 Intervet International B.V. Heteroaryl compounds with cyclic bridging unit for use in the treatment helminth infection
WO2013149940A1 (en) 2012-04-02 2013-10-10 Basf Se Acrylamide compounds for combating invertebrate pests
EP2833866B2 (en) 2012-04-04 2024-11-27 Intervet International B.V. Soft chewable pharmaceutical products
CN108478577A (zh) 2012-04-05 2018-09-04 沃泰克斯药物股份有限公司 可用作atr激酶抑制剂的化合物及其组合疗法
NZ701185A (en) 2012-04-20 2015-08-28 Merial Ltd Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
WO2013167633A1 (en) 2012-05-09 2013-11-14 Basf Se Acrylamide compounds for combating invertebrate pests
WO2014001120A1 (en) * 2012-06-25 2014-01-03 Syngenta Participations Ag Isothiazole derivatives as insecticidal compounds
US9867375B2 (en) 2012-07-31 2018-01-16 Syngenta Participations Ag Methods of pest control in soybean
CN104520287A (zh) 2012-08-03 2015-04-15 先正达参股股份有限公司 控制昆虫的方法
US20150152070A1 (en) 2012-08-03 2015-06-04 Syngenta Paricipations Ag Methods of pest control in soybean
WO2014019950A1 (en) 2012-08-03 2014-02-06 Syngenta Participations Ag Methods of pest control in soybean
WO2014029709A1 (en) 2012-08-24 2014-02-27 Syngenta Participations Ag Methods of controlling insects
WO2014029708A1 (en) * 2012-08-24 2014-02-27 Syngenta Participations Ag Methods of controlling insects
RU2636978C2 (ru) 2012-08-24 2017-11-29 Зингента Партисипейшнс Аг Способы борьбы с почвенными вредителями
JP6238987B2 (ja) 2012-08-24 2017-11-29 シンジェンタ パーティシペーションズ アーゲー 昆虫を防除する方法
CA2882199A1 (en) 2012-09-04 2014-03-13 Zoetis Llc Spirocyclic isoxazoline derivatives for treatment of sea lice
DK2904406T3 (en) 2012-10-04 2018-06-18 Vertex Pharma METHOD OF DETERMINING THE ATR INHIBITION, INCREASED DNA DAMAGE
EP2909202A1 (en) 2012-10-16 2015-08-26 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of atr kinase
PL2922845T3 (pl) 2012-11-20 2018-11-30 Merial, Inc. Związki przeciwrobacze oraz ich kompozycje i sposób stosowania
SI2941432T1 (en) 2012-12-07 2018-07-31 Vertex Pharmaceuticals Incorporated 2-AMINO-6-FLUORO-N- (5-FLUORO-4- (4- (4- (OXETHAN-3-YL) PIPERAZIN-1-CARBONYL) PIPERIDIN-1-YLIPRIDIN-3-YL) 1,5 ALFA) PYRIMIDINE-3-CARBOXAMIDE AS ATR KINAZE INHIBITOR
WO2014143240A1 (en) 2013-03-15 2014-09-18 Vertex Pharmaceuticals Incorporated Fused pyrazolopyrimidine derivatives useful as inhibitors of atr kinase
EP3013807B1 (en) * 2013-06-24 2020-04-08 Boehringer Ingelheim Animal Health USA Inc. Naphthyl-substituted isothiazoline compounds
CN103539694B (zh) * 2013-09-12 2015-09-16 中国农业科学院植物保护研究所 一种多取代菊酰苯胺类衍生物及其应用
DK3063144T3 (da) 2013-11-01 2021-10-25 Boehringer Ingelheim Animal Health Usa Inc Antiparasitære og pesticid-isoxazolinforbindelser
PT3077397T (pt) 2013-12-06 2020-01-22 Vertex Pharma Composto de 2-amino-6-fluoro-n-[5-fluoro-piridin-3-il]pirazolo[1,5-a]pirimidin-3-carboxamida útil como inibidor da atr quinase, a sua preparação, diferentes formas sólidas e derivados radiomarcados do mesmo
WO2015104422A1 (en) 2014-01-13 2015-07-16 Basf Se Dihydrothiophene compounds for controlling invertebrate pests
BR112016023898A8 (pt) 2014-04-17 2021-03-30 Basf Se uso de compostos malononitrila para proteger animais de parasitas
CA2949511A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Anthelmintic compounds
MX373102B (es) 2014-06-05 2020-04-17 Vertex Pharma Derivados radiomarcados de un compuesto de 2-amino-6-fluoro-n-[5-fluoro-piridin-3-il]-pirazolo[1,5-a]pirimidin-3-carboxamida útil como inhibidor de ataxia telangiectasia mutada y rad3 relacionado (atr) cinasa, preparación de tal compuesto y diferentes formas sólidas del mismo.
WO2015191382A1 (en) * 2014-06-11 2015-12-17 E. I. Du Pont De Nemours And Company Fungicidal tetrazolinones
SG11201610500WA (en) 2014-06-17 2017-01-27 Vertex Pharma Method for treating cancer using a combination of chk1 and atr inhibitors
CN106536481B (zh) 2014-06-19 2019-11-22 勃林格殷格翰动物保健美国公司 包含吲哚衍生物的杀寄生物的组合物、其用法和用途
WO2016069983A1 (en) 2014-10-31 2016-05-06 Merial, Inc. Parasiticidal composition comprising fipronil
GB2538028B (en) 2015-01-16 2017-02-08 Avista Pharma Solutions Antiparasitic compounds
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
EA036272B1 (ru) 2015-04-08 2020-10-21 БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. Инъецируемые препараты замедленного высвобождения, содержащие изоксазолиновое действующее вещество, способы и применение
CN107835818B (zh) 2015-05-20 2022-04-29 勃林格殷格翰动物保健美国公司 驱虫缩酚酸肽化合物
HUE059228T2 (hu) 2015-06-23 2022-10-28 Intervet Int Bv E vitamint tartalmazó izoxazolin oldat, fertõtlenített ivóvízzel való felhasználásra
AU2016331955B2 (en) 2015-09-30 2022-07-21 Vertex Pharmaceuticals Incorporated Method for treating cancer using a combination of DNA damaging agents and ATR inhibitors
UY40429A (es) 2016-02-24 2023-10-13 Boehringer Ingelheim Animal Health Usa Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
DK3440062T3 (da) 2016-04-06 2022-01-03 Boehringer Ingelheim Animal Health Usa Inc Fremgangsmåde til fremstillingen af enantiomerisk berigede isoxazolinforbindelser - krystallinsk toluensolvat af (s)-afoxolaner
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
AU2017344097A1 (en) 2016-10-14 2019-05-02 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
US10961213B2 (en) 2017-01-25 2021-03-30 Basf Se Process for preparation of benzylic amides
AR111260A1 (es) 2017-03-31 2019-06-19 Intervet Int Bv Formulación farmacéutica de la sal de crotonil amino piridina
MX2020001724A (es) 2017-08-14 2020-07-29 Boehringer Ingelheim Animal Health Usa Inc Compuestos de pirazol-isoxazolina plaguicidas y parasiticidas.
JP2021503465A (ja) 2017-11-16 2021-02-12 アビスタ ファーマ ソリューションズ，インコーポレーテッド 単一エナンチオマーの抗寄生生物化合物
AU2018385766B2 (en) 2017-12-15 2022-12-01 Tarsus Pharmaceuticals, Inc. Isoxazoline parasiticide formulations and methods for treating blepharitis
AR113997A1 (es) 2017-12-21 2020-07-08 Intervet Int Bv Composiciones antiparasitarias para unción dorsal continua
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
TWI812673B (zh) * 2018-02-12 2023-08-21 美商富曼西公司 用於防治無脊椎害蟲之萘異噁唑啉化合物
WO2020002593A1 (en) 2018-06-29 2020-01-02 Intervet International B.V. Compound for use against helminthic infection
US12269822B2 (en) 2018-07-09 2025-04-08 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic heterocyclic compounds
CN112955426A (zh) 2018-10-29 2021-06-11 巴斯夫欧洲公司 制备光学富集的羟醛化合物的方法
CN109293478B (zh) * 2018-11-02 2021-08-06 大连奇凯医药科技有限公司 一种制备四氟苯甲醇的方法
WO2020112374A1 (en) 2018-11-20 2020-06-04 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
WO2020150032A1 (en) 2019-01-16 2020-07-23 Boehringer Ingelheim Animal Health USA Inc. Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
UY38599A (es) 2019-03-01 2020-08-31 Boehringer Ingelheim Animal Health Usa Inc Composiciones inyectables de clorsulón, sus métodos y usos
MX2021011302A (es) 2019-03-19 2022-01-19 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos.
AR119790A1 (es) 2019-08-29 2022-01-12 Pi Industries Ltd Compuestos de isoxazolina y su uso como agentes para el control de plagas
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물
CN116897044A (zh) 2020-12-21 2023-10-17 勃林格殷格翰动物保健有限公司 包含异噁唑啉化合物的杀寄生虫环
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
JP7824305B2 (ja) 2021-01-27 2026-03-04 コルテバ アグリサイエンス エルエルシー 魚における寄生生物に対するシクロプロピルアミド化合物
US12258193B2 (en) 2022-02-17 2025-03-25 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer
CN115594645B (zh) * 2022-11-08 2023-04-14 山东亚华生物科技有限公司 一种氟雷拉纳的合成方法
CN121620507A (zh) 2023-08-02 2026-03-06 英特维特国际股份有限公司 具有驱虫活性的甲酰胺-4-喹啉化合物
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI21137A (sl) 2002-01-24 2003-08-31 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Derivati azafenilalanina
EP1538138A4 (en) 2002-08-26 2007-07-25 Nissan Chemical Ind Ltd SUBSTITUTED BENZANILIDE COMPOUND AND PROTECTIVE AGENTS
AU2005219788B2 (en) 2004-03-05 2010-06-03 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and noxious organism control agent
TW200803740A (en) * 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
BRPI0707091B8 (pt) 2006-03-10 2018-02-14 Nissan Chemical Ind Ltd composto de isoxalina e benzaldoxima substituído ou um sal do mesmo; pesticida, agroquímico, endo- ou ecto-parasiticidapara mamíferos ou pássaros, inseticida e acaricida contendo como um ou mais ingredientes ativos selecionados a partir do composto de isoxalina substituído e o sal do mesmo
US8367584B2 (en) * 2007-10-03 2013-02-05 E.I. Du Pont De Nemours And Company Naphthalene isoxazoline compounds for control of invertebrate pests

Also Published As

Publication number Publication date
DOP2009000227A (es) 2010-01-31
SV2009003376A (es) 2010-05-17
CA2683180A1 (en) 2008-10-16
AU2008235089A1 (en) 2008-10-16
BRPI0810196A2 (pt) 2011-12-06
KR20090130064A (ko) 2009-12-17
AU2008235089C1 (en) 2014-04-03
JP5548119B2 (ja) 2014-07-16
CO6231032A2 (es) 2010-12-20
UY30992A1 (es) 2008-11-28
AU2008235089B2 (en) 2013-10-31
NZ580241A (en) 2011-02-25
TW200847925A (en) 2008-12-16
US20100179194A1 (en) 2010-07-15
IL200634A0 (en) 2010-05-17
MY146638A (en) 2012-09-14
RU2009141185A (ru) 2011-05-20
CR11038A (es) 2010-01-19
WO2008122375A3 (en) 2009-01-15
AU2008235089A8 (en) 2014-04-10
EP2181100A2 (en) 2010-05-05
AR065985A1 (es) 2009-07-15
US8372867B2 (en) 2013-02-12
AU2008235089B8 (en) 2014-04-10
MX2009010071A (es) 2009-10-16
JP2010523604A (ja) 2010-07-15
PE20090800A1 (es) 2009-07-25
WO2008122375A2 (en) 2008-10-16
CL2008000962A1 (es) 2008-10-24
ZA200907045B (en) 2011-06-29

Similar Documents

Publication Publication Date Title
ECSP099648A (es) Derivados de aril isoxazolina insecticidas
ECSP099684A (es) Aril pirrolidinas insecticidas
EA201000544A1 (ru) Производные спирогетероциклического пирролидиндиона, применимые в качестве пестицидов
CO6480909A2 (es) Derivados de tiazolilpiperidina como fungicidas.
BR112013004920A2 (pt) "composições pesticidas".
UA107791C2 (en) Pesticidal compositions
DOP2010000225A (es) Arilpirrolinas insecticidas
CO7121338A2 (es) Derivados de sulfuro de trifluoroetilo sustituidos con n-arilamidina como acaricidas e insecticidas
CR11241A (es) Compuestos de pirazol y su uso como inhibidores de raf
CO6390027A2 (es) N-oxipiperidinas espiroheterociclicas como pesticidas
BR112012027439A2 (pt) derivados de n1-sulfonil-5-flúor-pirimidinona n3-substituídos
BR112013010320A2 (pt) composições pesticidas e processos relacionados a elas
CO6390084A2 (es) Composiciones insecticidas estables y métodos para producir las mismas
UA110657C2 (uk) Сільськогосподарська і садова фунгіцидна композиція
BR112013009823A2 (pt) novos compostos heterocíclicos como pesticidas
UY33070A (es) Compuestos insecticidas basados en derivados de isoxazolina
CO6630158A2 (es) Derivados de cetoheteroarilpiperidina y de cetoheteroarilpiperazina como fungicidas
CU20130018A7 (es) Mezclas insecticidas sinérgicas
UY31688A1 (es) Plaguicidas
UY34251A (es) derivados de isoxazolina como compuestos insecticidas.
EP2578587A4 (en) PYRAZOLE DERIVATIVES
UY33330A (es) Antranilamidas sustituidas con triazol como plaguicidas
CO6251376A2 (es) Triazolilpiridina cetonas herbicidas
GT200700057A (es) Nuevos derivados de piridazina
CY1115110T1 (el) Συμπυκνωμενη συνθεση κυπερμεθρινης