ECSP10010626A - Derivados de iminopiridina y su uso - Google Patents
Derivados de iminopiridina y su usoInfo
- Publication number
- ECSP10010626A ECSP10010626A EC2010010626A ECSP10010626A ECSP10010626A EC SP10010626 A ECSP10010626 A EC SP10010626A EC 2010010626 A EC2010010626 A EC 2010010626A EC SP10010626 A ECSP10010626 A EC SP10010626A EC SP10010626 A ECSP10010626 A EC SP10010626A
- Authority
- EC
- Ecuador
- Prior art keywords
- iminopiridine
- derivatives
- present
- compound
- iminopyridine
- Prior art date
Links
- 108060003345 Adrenergic Receptor Proteins 0.000 abstract 1
- 102000017910 Adrenergic receptor Human genes 0.000 abstract 1
- 208000026723 Urinary tract disease Diseases 0.000 abstract 1
- 208000012931 Urologic disease Diseases 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 derivative of iminopyridine compound Chemical class 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 208000014001 urinary system disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
La presente invención pretende proporcionar un derivado de compuesto de iminopiridina que tiene una acción antagonista del receptor adrenérgico 1D, que es útil como un agente para la profilaxis o el tratamiento una enfermedad del tracto urinario inferior y similares. La presente invención provee un compuesto representado por la fórmula:en el cual cada símbolo es como se define en la memoria descriptiva, o una de sus sales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008113135 | 2008-04-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP10010626A true ECSP10010626A (es) | 2011-03-31 |
Family
ID=40821652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010010626A ECSP10010626A (es) | 2008-04-23 | 2010-11-23 | Derivados de iminopiridina y su uso |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US20090270393A1 (es) |
| EP (1) | EP2271624B9 (es) |
| JP (1) | JP5462803B2 (es) |
| KR (1) | KR20100130235A (es) |
| CN (1) | CN102066327B (es) |
| AR (1) | AR071392A1 (es) |
| AU (1) | AU2009238938A1 (es) |
| BR (1) | BRPI0910737A2 (es) |
| CA (1) | CA2723216C (es) |
| CL (1) | CL2009000964A1 (es) |
| CO (1) | CO6260091A2 (es) |
| CR (1) | CR11765A (es) |
| DO (1) | DOP2010000321A (es) |
| EA (1) | EA019641B1 (es) |
| EC (1) | ECSP10010626A (es) |
| ES (1) | ES2478823T3 (es) |
| GE (1) | GEP20135883B (es) |
| IL (1) | IL208771A0 (es) |
| MX (1) | MX2010011652A (es) |
| NZ (1) | NZ588909A (es) |
| PE (1) | PE20091784A1 (es) |
| TW (1) | TW200948784A (es) |
| UY (1) | UY31781A (es) |
| WO (1) | WO2009131245A1 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8481569B2 (en) | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8470859B2 (en) * | 2006-10-23 | 2013-06-25 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| US20110039892A1 (en) * | 2008-04-23 | 2011-02-17 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| PE20091784A1 (es) * | 2008-04-23 | 2009-12-05 | Takeda Pharmaceutical | Derivados de iminopiridina con actividad sobre el receptor adrenergico alfa 1d |
| US9695118B2 (en) | 2012-04-24 | 2017-07-04 | Chugai Seiyaku Kabushiki Kaisha | Benzamide derivative |
| KR20150003849A (ko) | 2012-04-24 | 2015-01-09 | 추가이 세이야쿠 가부시키가이샤 | 퀴나졸린디온 유도체 |
| CN103058913B (zh) * | 2012-12-13 | 2015-09-30 | 江苏弘和药物研发有限公司 | 5-氯异吲哚酮的合成方法 |
| KR20160073413A (ko) | 2013-10-23 | 2016-06-24 | 추가이 세이야쿠 가부시키가이샤 | 퀴나졸리논 및 이소퀴놀리논 유도체 |
| TW201609654A (zh) * | 2014-05-28 | 2016-03-16 | 安斯泰來製藥股份有限公司 | 吡啶衍生物 |
| CN111217731B (zh) * | 2020-02-19 | 2022-06-03 | 广东工业大学 | 一种邻位亚胺酯或氰基取代的芳基硫醚衍生物及制备与应用 |
| CN115703722B (zh) * | 2021-08-03 | 2024-06-25 | 江苏国泰超威新材料有限公司 | 一种n,n-二甲基三氟甲基磺酰胺的制备方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2540109B1 (fr) * | 1983-01-28 | 1985-08-30 | Logeais Labor Jacques | Imino-2 pyrrolidines, leur procede de preparation et leurs applications en therapeutique |
| DE4021439A1 (de) * | 1989-12-14 | 1991-06-20 | Bayer Ag | 2-iminopyridin-derivate |
| US5688795A (en) * | 1994-11-08 | 1997-11-18 | Syntex (U.S.A.) Inc. | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists |
| UA52681C2 (uk) * | 1997-04-08 | 2003-01-15 | Янссен Фармацевтика Н.В. | Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі |
| US6218396B1 (en) * | 1998-02-20 | 2001-04-17 | Orth-Mcneil Pharmaceutical, Inc. | Substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia |
| US6153614A (en) * | 1998-07-16 | 2000-11-28 | Abbott Laboratories | Piperazinyl pyrimidine dione compounds selective for adrenoceptors |
| DE19845202A1 (de) * | 1998-10-01 | 2000-04-06 | Wella Ag | Haarwuchsmittel |
| ATE419239T1 (de) * | 2000-10-20 | 2009-01-15 | Eisai R&D Man Co Ltd | Verfahren zur herstellung von 4-phenoxy chinolin derivaten |
| FR2825705B1 (fr) * | 2001-06-08 | 2005-05-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
| US7375100B2 (en) * | 2003-06-04 | 2008-05-20 | Pfizer Inc | 2-amino-pyridine derivatives useful for the treatment of diseases |
| AU2005225632B2 (en) * | 2004-03-23 | 2011-08-04 | Pfizer Inc. | Formamide derivatives useful as adrenoceptor |
| ES2241496B1 (es) * | 2004-04-15 | 2006-12-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de piridina. |
| US20050288270A1 (en) * | 2004-05-27 | 2005-12-29 | Pfizer Inc | New aminopyridine derivatives and their use as pharmaceuticals |
| TW200700392A (en) * | 2005-03-16 | 2007-01-01 | Astrazeneca Ab | Novel compounds |
| ES2303758B1 (es) * | 2006-02-20 | 2009-08-13 | Laboratorios Almirall S.A. | Nuevos derivados de piridin-3-amina. |
| US8470859B2 (en) * | 2006-10-23 | 2013-06-25 | Takeda Pharmaceutical Company Limited | Iminopyridine derivative and use thereof |
| US8293747B2 (en) * | 2007-07-19 | 2012-10-23 | Merck Sharp & Dohme Corp. | Heterocyclic amide compounds as protein kinase inhibitors |
| EA201001456A1 (ru) * | 2008-03-21 | 2011-06-30 | Новартис Аг | Новые гетероциклические соединения и их применение |
| PE20091784A1 (es) * | 2008-04-23 | 2009-12-05 | Takeda Pharmaceutical | Derivados de iminopiridina con actividad sobre el receptor adrenergico alfa 1d |
| US8290250B2 (en) * | 2008-12-26 | 2012-10-16 | Five Apes, Inc. | Method and apparatus for creating a pattern recognizer |
-
2009
- 2009-04-22 PE PE2009000559A patent/PE20091784A1/es not_active Application Discontinuation
- 2009-04-22 GE GEAP200912013A patent/GEP20135883B/en unknown
- 2009-04-22 US US12/428,368 patent/US20090270393A1/en not_active Abandoned
- 2009-04-22 UY UY0001031781A patent/UY31781A/es not_active Application Discontinuation
- 2009-04-22 EA EA201071229A patent/EA019641B1/ru not_active IP Right Cessation
- 2009-04-22 NZ NZ588909A patent/NZ588909A/xx not_active IP Right Cessation
- 2009-04-22 BR BRPI0910737A patent/BRPI0910737A2/pt not_active IP Right Cessation
- 2009-04-22 JP JP2010541619A patent/JP5462803B2/ja not_active Expired - Fee Related
- 2009-04-22 AU AU2009238938A patent/AU2009238938A1/en not_active Abandoned
- 2009-04-22 EP EP09734608.4A patent/EP2271624B9/en active Active
- 2009-04-22 MX MX2010011652A patent/MX2010011652A/es active IP Right Grant
- 2009-04-22 KR KR1020107025893A patent/KR20100130235A/ko not_active Withdrawn
- 2009-04-22 US US12/989,054 patent/US20110039846A1/en not_active Abandoned
- 2009-04-22 WO PCT/JP2009/058434 patent/WO2009131245A1/en not_active Ceased
- 2009-04-22 CA CA2723216A patent/CA2723216C/en not_active Expired - Fee Related
- 2009-04-22 TW TW098113294A patent/TW200948784A/zh unknown
- 2009-04-22 CN CN2009801238758A patent/CN102066327B/zh not_active Expired - Fee Related
- 2009-04-22 CL CL2009000964A patent/CL2009000964A1/es unknown
- 2009-04-22 AR ARP090101416A patent/AR071392A1/es not_active Application Discontinuation
- 2009-04-22 ES ES09734608.4T patent/ES2478823T3/es active Active
-
2010
- 2010-10-17 IL IL208771A patent/IL208771A0/en unknown
- 2010-10-22 DO DO2010000321A patent/DOP2010000321A/es unknown
- 2010-10-27 CR CR11765A patent/CR11765A/es not_active Application Discontinuation
- 2010-11-19 CO CO10145079A patent/CO6260091A2/es active IP Right Grant
- 2010-11-23 EC EC2010010626A patent/ECSP10010626A/es unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8481569B2 (en) | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| EA019641B1 (ru) | 2014-05-30 |
| KR20100130235A (ko) | 2010-12-10 |
| US20110039846A1 (en) | 2011-02-17 |
| BRPI0910737A2 (pt) | 2019-09-24 |
| CN102066327A (zh) | 2011-05-18 |
| JP5462803B2 (ja) | 2014-04-02 |
| AU2009238938A1 (en) | 2009-10-29 |
| EP2271624A1 (en) | 2011-01-12 |
| NZ588909A (en) | 2012-08-31 |
| EP2271624B9 (en) | 2014-11-12 |
| CR11765A (es) | 2010-12-15 |
| CL2009000964A1 (es) | 2010-03-26 |
| MX2010011652A (es) | 2010-12-06 |
| TW200948784A (en) | 2009-12-01 |
| DOP2010000321A (es) | 2010-11-15 |
| WO2009131245A1 (en) | 2009-10-29 |
| GEP20135883B (en) | 2013-07-25 |
| PE20091784A1 (es) | 2009-12-05 |
| JP2011518766A (ja) | 2011-06-30 |
| ES2478823T3 (es) | 2014-07-23 |
| CN102066327B (zh) | 2013-05-29 |
| US20090270393A1 (en) | 2009-10-29 |
| CA2723216A1 (en) | 2009-10-29 |
| EP2271624B1 (en) | 2014-05-21 |
| CO6260091A2 (es) | 2011-03-22 |
| CA2723216C (en) | 2017-01-24 |
| AR071392A1 (es) | 2010-06-16 |
| EA201071229A1 (ru) | 2011-06-30 |
| IL208771A0 (en) | 2010-12-30 |
| UY31781A (es) | 2009-12-14 |
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