ECSP10010626A - Derivados de iminopiridina y su uso - Google Patents

Derivados de iminopiridina y su uso

Info

Publication number
ECSP10010626A
ECSP10010626A EC2010010626A ECSP10010626A ECSP10010626A EC SP10010626 A ECSP10010626 A EC SP10010626A EC 2010010626 A EC2010010626 A EC 2010010626A EC SP10010626 A ECSP10010626 A EC SP10010626A EC SP10010626 A ECSP10010626 A EC SP10010626A
Authority
EC
Ecuador
Prior art keywords
iminopiridine
derivatives
present
compound
iminopyridine
Prior art date
Application number
EC2010010626A
Other languages
English (en)
Inventor
Masato Yoshida
Nobuki Sakauchi
Ayumu Sato
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of ECSP10010626A publication Critical patent/ECSP10010626A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

La presente invención pretende proporcionar un derivado de compuesto de iminopiridina que tiene una acción antagonista del receptor adrenérgico 1D, que es útil como un agente para la profilaxis o el tratamiento una enfermedad del tracto urinario inferior y similares. La presente invención provee un compuesto representado por la fórmula:en el cual cada símbolo es como se define en la memoria descriptiva, o una de sus sales.
EC2010010626A 2008-04-23 2010-11-23 Derivados de iminopiridina y su uso ECSP10010626A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008113135 2008-04-23

Publications (1)

Publication Number Publication Date
ECSP10010626A true ECSP10010626A (es) 2011-03-31

Family

ID=40821652

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010626A ECSP10010626A (es) 2008-04-23 2010-11-23 Derivados de iminopiridina y su uso

Country Status (24)

Country Link
US (2) US20110039846A1 (es)
EP (1) EP2271624B9 (es)
JP (1) JP5462803B2 (es)
KR (1) KR20100130235A (es)
CN (1) CN102066327B (es)
AR (1) AR071392A1 (es)
AU (1) AU2009238938A1 (es)
BR (1) BRPI0910737A2 (es)
CA (1) CA2723216C (es)
CL (1) CL2009000964A1 (es)
CO (1) CO6260091A2 (es)
CR (1) CR11765A (es)
DO (1) DOP2010000321A (es)
EA (1) EA019641B1 (es)
EC (1) ECSP10010626A (es)
ES (1) ES2478823T3 (es)
GE (1) GEP20135883B (es)
IL (1) IL208771A0 (es)
MX (1) MX2010011652A (es)
NZ (1) NZ588909A (es)
PE (1) PE20091784A1 (es)
TW (1) TW200948784A (es)
UY (1) UY31781A (es)
WO (1) WO2009131245A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8481569B2 (en) 2008-04-23 2013-07-09 Takeda Pharmaceutical Company Limited Iminopyridine derivatives and use thereof

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8470859B2 (en) 2006-10-23 2013-06-25 Takeda Pharmaceutical Company Limited Iminopyridine derivative and use thereof
US20110039892A1 (en) * 2008-04-23 2011-02-17 Takeda Pharmaceutical Company Limited Iminopyridine derivative and use thereof
CL2009000964A1 (es) * 2008-04-23 2010-03-26 Takeda Pharmaceuticals Co Compuestos derivados de 1-aril-2-imino-1,2-dihidropiridina-3-carboxamida, antagonista del receptor adrenergico alfa 1d, composicion farmaceutica que los comprende; y su uso para el tratamiento o profilaxis de enfermedades del tracto urinario inferior.
BR112014026305A2 (pt) 2012-04-24 2017-06-27 Chugai Pharmaceutical Co Ltd derivado de quinazolidinadiona
BR112014026266A2 (pt) 2012-04-24 2017-06-27 Chugai Pharmaceutical Co Ltd derivado de quinazolidinadiona
CN103058913B (zh) * 2012-12-13 2015-09-30 江苏弘和药物研发有限公司 5-氯异吲哚酮的合成方法
US10005739B2 (en) 2013-10-23 2018-06-26 Chugai Seiyaku Kabushiki Kaisha Quinazolinone and isoquinolinone derivative
BR112016027729B1 (pt) * 2014-05-28 2020-11-17 Astellas Pharma Inc. composto derivado de piridina, composição farmacêutica contendo o referido composto e seu uso
CN111217731B (zh) * 2020-02-19 2022-06-03 广东工业大学 一种邻位亚胺酯或氰基取代的芳基硫醚衍生物及制备与应用
CN115703722B (zh) * 2021-08-03 2024-06-25 江苏国泰超威新材料有限公司 一种n,n-二甲基三氟甲基磺酰胺的制备方法

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FR2540109B1 (fr) * 1983-01-28 1985-08-30 Logeais Labor Jacques Imino-2 pyrrolidines, leur procede de preparation et leurs applications en therapeutique
DE4021439A1 (de) * 1989-12-14 1991-06-20 Bayer Ag 2-iminopyridin-derivate
US5688795A (en) * 1994-11-08 1997-11-18 Syntex (U.S.A.) Inc. 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists
UA52681C2 (uk) * 1997-04-08 2003-01-15 Янссен Фармацевтика Н.В. Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі
ZA991315B (en) * 1998-02-20 2000-11-20 Ortho Mcneil Pharm Inc Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia.
US6153614A (en) * 1998-07-16 2000-11-28 Abbott Laboratories Piperazinyl pyrimidine dione compounds selective for adrenoceptors
DE19845202A1 (de) * 1998-10-01 2000-04-06 Wella Ag Haarwuchsmittel
EP1415987B1 (en) * 2000-10-20 2007-02-28 Eisai R&D Management Co., Ltd. Nitrogenous aromatic ring compounds as anti cancer agents
FR2825705B1 (fr) * 2001-06-08 2005-05-20 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
US7375100B2 (en) * 2003-06-04 2008-05-20 Pfizer Inc 2-amino-pyridine derivatives useful for the treatment of diseases
WO2005092840A1 (en) * 2004-03-23 2005-10-06 Pfizer Limited Formamide derivatives useful as adrenoceptor
ES2241496B1 (es) * 2004-04-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridina.
US20050288270A1 (en) * 2004-05-27 2005-12-29 Pfizer Inc New aminopyridine derivatives and their use as pharmaceuticals
TW200700392A (en) * 2005-03-16 2007-01-01 Astrazeneca Ab Novel compounds
ES2303758B1 (es) * 2006-02-20 2009-08-13 Laboratorios Almirall S.A. Nuevos derivados de piridin-3-amina.
US8470859B2 (en) * 2006-10-23 2013-06-25 Takeda Pharmaceutical Company Limited Iminopyridine derivative and use thereof
WO2009014637A2 (en) * 2007-07-19 2009-01-29 Schering Corporation Heterocyclic amide compounds as protein kinase inhibitors
BRPI0908906A2 (pt) * 2008-03-21 2019-09-24 Novartis Ag compostos heterocíclicos e usos dos mesmos
CL2009000964A1 (es) * 2008-04-23 2010-03-26 Takeda Pharmaceuticals Co Compuestos derivados de 1-aril-2-imino-1,2-dihidropiridina-3-carboxamida, antagonista del receptor adrenergico alfa 1d, composicion farmaceutica que los comprende; y su uso para el tratamiento o profilaxis de enfermedades del tracto urinario inferior.
US8290250B2 (en) * 2008-12-26 2012-10-16 Five Apes, Inc. Method and apparatus for creating a pattern recognizer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8481569B2 (en) 2008-04-23 2013-07-09 Takeda Pharmaceutical Company Limited Iminopyridine derivatives and use thereof

Also Published As

Publication number Publication date
CO6260091A2 (es) 2011-03-22
CA2723216A1 (en) 2009-10-29
BRPI0910737A2 (pt) 2019-09-24
US20090270393A1 (en) 2009-10-29
ES2478823T3 (es) 2014-07-23
KR20100130235A (ko) 2010-12-10
EA201071229A1 (ru) 2011-06-30
NZ588909A (en) 2012-08-31
US20110039846A1 (en) 2011-02-17
EP2271624B1 (en) 2014-05-21
JP5462803B2 (ja) 2014-04-02
UY31781A (es) 2009-12-14
EP2271624A1 (en) 2011-01-12
AU2009238938A1 (en) 2009-10-29
IL208771A0 (en) 2010-12-30
DOP2010000321A (es) 2010-11-15
EA019641B1 (ru) 2014-05-30
PE20091784A1 (es) 2009-12-05
AR071392A1 (es) 2010-06-16
CR11765A (es) 2010-12-15
EP2271624B9 (en) 2014-11-12
CL2009000964A1 (es) 2010-03-26
MX2010011652A (es) 2010-12-06
WO2009131245A1 (en) 2009-10-29
CN102066327A (zh) 2011-05-18
CN102066327B (zh) 2013-05-29
TW200948784A (en) 2009-12-01
GEP20135883B (en) 2013-07-25
CA2723216C (en) 2017-01-24
JP2011518766A (ja) 2011-06-30

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