CL2009001349A1 - Compuestos derivados de urea sustituidos con 1,4-dihidroquinolin-4-ona, inhibidores de adn girasa bacteriana y/o topoisomerasa iv bacteriana; composicion farmceutica; util para el tratamiento de una infeccion bacteriana. - Google Patents

Compuestos derivados de urea sustituidos con 1,4-dihidroquinolin-4-ona, inhibidores de adn girasa bacteriana y/o topoisomerasa iv bacteriana; composicion farmceutica; util para el tratamiento de una infeccion bacteriana.

Info

Publication number
CL2009001349A1
CL2009001349A1 CL2009001349A CL2009001349A CL2009001349A1 CL 2009001349 A1 CL2009001349 A1 CL 2009001349A1 CL 2009001349 A CL2009001349 A CL 2009001349A CL 2009001349 A CL2009001349 A CL 2009001349A CL 2009001349 A1 CL2009001349 A1 CL 2009001349A1
Authority
CL
Chile
Prior art keywords
bacterial
useful
pharmaceutical composition
dihydroquinolin
treatment
Prior art date
Application number
CL2009001349A
Other languages
English (en)
Inventor
Pamela Hill
Brian Sherer
John Irvin Manchester
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40823415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2009001349(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CL2009001349A1 publication Critical patent/CL2009001349A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Compuestos derivados de urea heterocíclicos, composición farmacéutica, útil para preparar un medicamento inhibidor de la ADN girasa bacteriana y/o topoisomerasa IV bacteriana y por lo tanto útil para tratar una infección bacteriana.
CL2009001349A 2008-06-04 2009-06-03 Compuestos derivados de urea sustituidos con 1,4-dihidroquinolin-4-ona, inhibidores de adn girasa bacteriana y/o topoisomerasa iv bacteriana; composicion farmceutica; util para el tratamiento de una infeccion bacteriana. CL2009001349A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5873608P 2008-06-04 2008-06-04

Publications (1)

Publication Number Publication Date
CL2009001349A1 true CL2009001349A1 (es) 2010-12-31

Family

ID=40823415

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009001349A CL2009001349A1 (es) 2008-06-04 2009-06-03 Compuestos derivados de urea sustituidos con 1,4-dihidroquinolin-4-ona, inhibidores de adn girasa bacteriana y/o topoisomerasa iv bacteriana; composicion farmceutica; util para el tratamiento de una infeccion bacteriana.

Country Status (23)

Country Link
US (1) US8283361B2 (es)
EP (1) EP2300463A1 (es)
JP (1) JP2011522026A (es)
KR (1) KR20110014710A (es)
CN (1) CN102105469A (es)
AR (1) AR072045A1 (es)
AU (1) AU2009254930A1 (es)
BR (1) BRPI0915471A2 (es)
CA (1) CA2725568A1 (es)
CL (1) CL2009001349A1 (es)
CO (1) CO6382176A2 (es)
CR (1) CR11825A (es)
DO (1) DOP2010000373A (es)
EA (1) EA201001858A1 (es)
EC (1) ECSP10010664A (es)
IL (1) IL209503A0 (es)
MX (1) MX2010013310A (es)
PE (1) PE20100155A1 (es)
SV (1) SV2010003752A (es)
TW (1) TW201000475A (es)
UY (1) UY31864A (es)
WO (1) WO2009147433A1 (es)
ZA (1) ZA201008610B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1849465A4 (en) * 2005-02-18 2008-12-24 Takeda Pharmaceutical AGENS TO CONTROL THE FUNCTION OF THE GPR34 RECEPTOR
TW201102065A (en) * 2009-05-29 2011-01-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
US20100317624A1 (en) * 2009-06-08 2010-12-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
EP2552893B1 (en) 2010-03-31 2014-10-29 Actelion Pharmaceuticals Ltd. Antibacterial isoquinolin-3-ylurea derivatives
AR088729A1 (es) 2011-03-29 2014-07-02 Actelion Pharmaceuticals Ltd Derivados de 3-ureidoisoquinolin-8-ilo y una composicion farmaceutica
CN105067814A (zh) * 2015-07-24 2015-11-18 中国科学院成都生物研究所 解旋酶水解atp活性测定方法
US11857352B2 (en) 2016-09-06 2024-01-02 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
WO2018074880A2 (ko) * 2016-10-20 2018-04-26 한국화학연구원 퀴놀린 4-온 유도체 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 폐렴의 예방 또는 치료용 약학적 조성물
RU2019133662A (ru) 2017-03-24 2021-04-26 Тайсо Фармасьютикал Ко., Лтд. Производное 2(1h)-хинолинона
CN111808089B (zh) * 2019-04-10 2023-04-11 四川大学华西医院 一种治疗糖尿病的药物依格列净或其衍生物的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0589985A1 (en) 1991-06-21 1994-04-06 Boehringer Mannheim Italia S.P.A. 2-amino-4-aryl-thiazoles with antiasthmatic and anti-inflammatory activities on the respiratory tract
PL362691A1 (en) 2000-12-15 2004-11-02 Vertex Pharmaceuticals Incorporated Bacterial gyrase inhibitors and uses thereof
AR042956A1 (es) 2003-01-31 2005-07-13 Vertex Pharma Inhibidores de girasa y usos de los mismos
US20080269214A1 (en) * 2005-03-04 2008-10-30 Astrazeneca Ab Pyrrole Derivatives as Dna Gyrase and Topoisomerase Inhibitors
US8022816B2 (en) 2005-03-21 2011-09-20 Vela Systems, Inc. System and method for field management using radio frequency tags
US7569907B2 (en) 2005-03-28 2009-08-04 Cooper Technologies Company Hybrid chip fuse assembly having wire leads and fabrication method therefor
JP2008538047A (ja) 2005-04-13 2008-10-02 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 位相変調に先立つ透かし入れのあるエンコード
BRPI0620196A2 (pt) * 2005-12-23 2013-01-15 Astrazeneca Ab composto, processo para a preparaÇço do mesmo, composiÇço farmacÊutica, uso de um composto, e, mÉtodos para a produÇço de um efeito antibacteriano em um animal de sangue quente, para a inibiÇço de dna girase e/ou topoisomerase iv bacteriana em um animal de sangue quente e para o tratamento de uma infecÇço bacteriana em um animal de sangue quente
DE102006012337B3 (de) 2006-03-17 2007-11-29 Amphenol-Tuchel Electronics Gmbh Elektrischer Steckverbinder
UA96964C2 (ru) * 2006-12-04 2011-12-26 Астразенека Аб Соединения полициклической мочевины с антибактериальными свойствами
CN201038186Y (zh) 2007-03-08 2008-03-19 鹤山丽得电子实业有限公司 一种大功率led
TW200940537A (en) 2008-02-26 2009-10-01 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
WO2009110688A2 (ko) 2008-03-06 2009-09-11 Jang Gum Sik 태양광 발전 장치
US20100317624A1 (en) * 2009-06-08 2010-12-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof

Also Published As

Publication number Publication date
JP2011522026A (ja) 2011-07-28
ECSP10010664A (es) 2011-01-31
DOP2010000373A (es) 2011-01-15
EP2300463A1 (en) 2011-03-30
US20100190745A1 (en) 2010-07-29
WO2009147433A1 (en) 2009-12-10
ZA201008610B (en) 2012-08-29
UY31864A (es) 2010-01-29
CA2725568A1 (en) 2009-12-10
PE20100155A1 (es) 2010-03-25
IL209503A0 (en) 2011-01-31
KR20110014710A (ko) 2011-02-11
EA201001858A1 (ru) 2011-08-30
AR072045A1 (es) 2010-08-04
MX2010013310A (es) 2011-03-01
CN102105469A (zh) 2011-06-22
CR11825A (es) 2011-02-04
AU2009254930A1 (en) 2009-12-10
SV2010003752A (es) 2011-04-14
CO6382176A2 (es) 2012-02-15
BRPI0915471A2 (pt) 2017-06-27
US8283361B2 (en) 2012-10-09
TW201000475A (en) 2010-01-01

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