ECSP13012877A - FORMAS SÓLIDAS SDE 3- (5-AMINO-2-metil -4- oxo-4H-QUINAZOL1N-3-IL) - PIPERIDIN-2, 6-DIONA, Y SUS COMPOSICIONES FARMACÉUTICAS Y USOS - Google Patents

FORMAS SÓLIDAS SDE 3- (5-AMINO-2-metil -4- oxo-4H-QUINAZOL1N-3-IL) - PIPERIDIN-2, 6-DIONA, Y SUS COMPOSICIONES FARMACÉUTICAS Y USOS

Info

Publication number
ECSP13012877A
ECSP13012877A ECSP13012877A ECSP13012877A EC SP13012877 A ECSP13012877 A EC SP13012877A EC SP13012877 A ECSP13012877 A EC SP13012877A EC SP13012877 A ECSP13012877 A EC SP13012877A
Authority
EC
Ecuador
Prior art keywords
piperidin
oxo
amino
methyl
quinazol1n
Prior art date
Application number
Other languages
English (en)
Inventor
Benjamin Max Cohen
William Wei-Hwa Leong
Hon-Wah Man
George W Muller
Ying Li
Jean Xu
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45888486&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP13012877(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of ECSP13012877A publication Critical patent/ECSP13012877A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describen formas sólidas que comprenden 3-(5-amino-2-metil-4-oxo-4H-quinazolin-3-il)-piperidin-2,6-diona, composiciones que comprenden las formas sólidas, métodos de elaborar las formas sólidas y métodos de sus usos.
ECSP13012877 2011-03-11 2013-09-11 FORMAS SÓLIDAS SDE 3- (5-AMINO-2-metil -4- oxo-4H-QUINAZOL1N-3-IL) - PIPERIDIN-2, 6-DIONA, Y SUS COMPOSICIONES FARMACÉUTICAS Y USOS ECSP13012877A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161451806P 2011-03-11 2011-03-11

Publications (1)

Publication Number Publication Date
ECSP13012877A true ECSP13012877A (es) 2013-10-31

Family

ID=45888486

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP13012877 ECSP13012877A (es) 2011-03-11 2013-09-11 FORMAS SÓLIDAS SDE 3- (5-AMINO-2-metil -4- oxo-4H-QUINAZOL1N-3-IL) - PIPERIDIN-2, 6-DIONA, Y SUS COMPOSICIONES FARMACÉUTICAS Y USOS

Country Status (36)

Country Link
US (5) US8802685B2 (es)
EP (2) EP3309153A1 (es)
JP (1) JP5959543B2 (es)
KR (1) KR20140014221A (es)
CN (2) CN106083812A (es)
AR (1) AR085650A1 (es)
AU (2) AU2012229279B2 (es)
BR (1) BR112013023279A2 (es)
CA (3) CA3037184C (es)
CL (1) CL2013002593A1 (es)
CO (1) CO6821939A2 (es)
CR (2) CR20130458A (es)
CY (1) CY1119974T1 (es)
DK (1) DK2683708T3 (es)
EA (1) EA026100B1 (es)
EC (1) ECSP13012877A (es)
ES (1) ES2656855T3 (es)
HR (1) HRP20180133T1 (es)
HU (1) HUE037955T2 (es)
LT (1) LT2683708T (es)
MX (1) MX2013010360A (es)
NI (1) NI201300080A (es)
NO (1) NO2683708T3 (es)
PE (1) PE20140983A1 (es)
PH (1) PH12013501821A1 (es)
PL (1) PL2683708T3 (es)
PT (1) PT2683708T (es)
RS (1) RS56770B1 (es)
RU (1) RU2611007C2 (es)
SG (1) SG192946A1 (es)
SI (1) SI2683708T1 (es)
SM (1) SMT201800032T1 (es)
TW (2) TWI540127B (es)
UA (1) UA113512C2 (es)
WO (1) WO2012125438A1 (es)
ZA (1) ZA201306234B (es)

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BR112018010964A2 (pt) 2015-12-02 2018-12-04 Celgene Corp terapia de ciclo usando 3-(5-amino-2-methil-4-oxo-4h-quinazolin-3-il)-piperidina-2,6-diona
US10830762B2 (en) 2015-12-28 2020-11-10 Celgene Corporation Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases
WO2017205622A1 (en) * 2016-05-25 2017-11-30 Savant Neglected Diseases, Llc Method of making benznidazole
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RU2695326C1 (ru) * 2018-06-05 2019-07-23 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт биомедицинской химии имени В.Н. Ореховича" (ИБМХ) Противоопухолевое средство для лечения рака предстательной железы в форме саше
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