ECSP19033211A - ANTICUERPOS ANTI–C1s Y MÉTODOS DE USO DE LOS MISMOS - Google Patents

ANTICUERPOS ANTI–C1s Y MÉTODOS DE USO DE LOS MISMOS

Info

Publication number
ECSP19033211A
ECSP19033211A ECSENADI201933211A ECDI201933211A ECSP19033211A EC SP19033211 A ECSP19033211 A EC SP19033211A EC SENADI201933211 A ECSENADI201933211 A EC SENADI201933211A EC DI201933211 A ECDI201933211 A EC DI201933211A EC SP19033211 A ECSP19033211 A EC SP19033211A
Authority
EC
Ecuador
Prior art keywords
antibodies
present
provides
methods
nucleic acids
Prior art date
Application number
ECSENADI201933211A
Other languages
English (en)
Inventor
Sandip Panicker
Graham Parry
Nancy E Stagliano
Original Assignee
Bioverativ Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Usa Inc filed Critical Bioverativ Usa Inc
Publication of ECSP19033211A publication Critical patent/ECSP19033211A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención proporciona anticuerpos que se enlazan de una forma específica con el componente de la vía del complemento C1s. La presente invención proporciona ácidos nucleicos que comprenden las secuencias de nucleótidos que codifican los anticuerpos anti–C1s; y las células huéspedes que comprenden los ácidos nucleicos. La presente invención proporciona composiciones que comprenden los anticuerpos anti–C1s. La presente invención proporciona los métodos de uso de los anticuerpos anti–C1s.
ECSENADI201933211A 2016-10-12 2019-05-10 ANTICUERPOS ANTI–C1s Y MÉTODOS DE USO DE LOS MISMOS ECSP19033211A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662407390P 2016-10-12 2016-10-12

Publications (1)

Publication Number Publication Date
ECSP19033211A true ECSP19033211A (es) 2019-07-31

Family

ID=61906346

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSENADI201933211A ECSP19033211A (es) 2016-10-12 2019-05-10 ANTICUERPOS ANTI–C1s Y MÉTODOS DE USO DE LOS MISMOS

Country Status (35)

Country Link
US (2) US20200048332A1 (es)
EP (2) EP3525583B8 (es)
JP (3) JP7069138B2 (es)
KR (3) KR102891406B1 (es)
CN (2) CN116554320A (es)
AR (1) AR110677A1 (es)
AU (3) AU2017341766A1 (es)
BR (1) BR112019007309A2 (es)
CA (1) CA3040253A1 (es)
CL (1) CL2019000975A1 (es)
CO (1) CO2019004741A2 (es)
CR (1) CR20190223A (es)
DK (1) DK3525583T3 (es)
DO (1) DOP2019000085A (es)
EA (1) EA201990884A1 (es)
EC (1) ECSP19033211A (es)
ES (1) ES3049257T3 (es)
FI (1) FI3525583T3 (es)
HR (1) HRP20251304T1 (es)
HU (1) HUE073475T2 (es)
IL (2) IL308156A (es)
LT (1) LT3525583T (es)
MX (2) MX2019004259A (es)
MY (1) MY198182A (es)
PE (1) PE20191031A1 (es)
PH (1) PH12019500789A1 (es)
PL (1) PL3525583T3 (es)
PT (1) PT3525583T (es)
RS (1) RS67326B1 (es)
SG (1) SG11201903012RA (es)
SI (1) SI3525583T1 (es)
TN (1) TN2019000109A1 (es)
TW (3) TWI846007B (es)
WO (1) WO2018071676A1 (es)
ZA (1) ZA201902247B (es)

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CN104870475B (zh) 2012-10-25 2019-11-08 美国比奥维拉迪维股份有限公司 抗补体C1s抗体和其用途
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CN116554320A (zh) 2016-10-12 2023-08-08 美国比奥维拉迪维股份有限公司 抗C1s抗体及其使用方法
EP3710589A4 (en) 2017-11-14 2021-11-10 Chugai Seiyaku Kabushiki Kaisha ANTI-C1S ANTIBODIES AND METHOD OF USING
BR112021021689A2 (pt) 2019-05-15 2022-03-22 Chugai Pharmaceutical Co Ltd Molécula de ligação a antígeno, composição farmacêutica, e método
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US20230235037A1 (en) * 2020-04-22 2023-07-27 Chemomab Ltd. Method of treatment using anti-ccl24 antibody
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MX2023001492A (es) * 2020-08-06 2023-03-08 Bioverativ Usa Inc Citocinas inflamatorias y fatiga en sujetos con una enfermedad mediada por el complemento.
CA3155939A1 (en) * 2021-04-30 2022-10-30 Upm-Kymmene Corporation A method for freeze-drying a hydrogel composition and a freeze-dried hydrogel composition
CN117769434A (zh) 2021-05-20 2024-03-26 黛安瑟斯医疗运营公司 与C1s结合的抗体和其用途
CN117642431B (zh) * 2021-07-13 2025-07-15 迈威(美国)生物治疗有限公司 抗c1s抗体和其用途
JP2025520434A (ja) 2022-06-15 2025-07-03 バイオベラティブ・ユーエスエイ・インコーポレイテッド 抗補体Ｃ１ｓ抗体製剤
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