EE03492B1 - Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid - Google Patents

Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid

Info

Publication number: EE03492B1
Authority: EE; Estonia
Prior art keywords: region; auto; retroviral vectors; direct expression; inactivating retroviral
Prior art date: 1994-09-02

Application number

EE9700040A

Other languages

English (en)

Other versions

EE9700040A (et

Inventor

Henry G�nzburg Walter

Michael Saller Robert

Original Assignee

GSF-Forschungszentrum f�r Umwelt und Gesundheit GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-02

Filing date

1995-09-01

Publication date

2001-08-15

1995-09-01 Application filed by GSF-Forschungszentrum f�r Umwelt und Gesundheit GmbH filed Critical GSF-Forschungszentrum f�r Umwelt und Gesundheit GmbH

1997-08-15 Publication of EE9700040A publication Critical patent/EE9700040A/et

2001-08-15 Publication of EE03492B1 publication Critical patent/EE03492B1/et

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Virology (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Plant Pathology (AREA)
Public Health (AREA)
Physics & Mathematics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Ceramic Products (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Traffic Control Systems (AREA)
Navigation (AREA)
Molds, Cores, And Manufacturing Methods Thereof (AREA)
Road Signs Or Road Markings (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Electrotherapy Devices (AREA)

EE9700040A 1994-09-02 1995-09-01 Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid EE03492B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK101794		1994-09-02
PCT/EP1995/003445 WO1996007748A1 (en)	1994-09-02	1995-09-01	Non self-inactivating, expression targeted retroviral vectors

Publications (2)

Publication Number	Publication Date
EE9700040A EE9700040A (et)	1997-08-15
EE03492B1 true EE03492B1 (et)	2001-08-15

Family

ID=8100062

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9700040A EE03492B1 (et)	1994-09-02	1995-09-01	Mitte-autoinaktiveeruvad ekspressiooni suunavad retroviiruslikud vektorid

Country Status (20)

Country	Link
US (1)	US7531353B1 (et)
EP (1)	EP0779929B1 (et)
JP (1)	JP4037446B2 (et)
CN (1)	CN1117156C (et)
AT (1)	ATE200517T1 (et)
AU (1)	AU688590B2 (et)
BR (1)	BR9508664A (et)
CA (1)	CA2198210C (et)
DE (1)	DE69520681T2 (et)
DK (1)	DK0779929T5 (et)
EE (1)	EE03492B1 (et)
ES (1)	ES2156945T3 (et)
FI (1)	FI970892A0 (et)
HU (1)	HU221607B (et)
MX (1)	MX9701544A (et)
NO (1)	NO317731B1 (et)
NZ (1)	NZ292897A (et)
PL (1)	PL184375B1 (et)
RU (1)	RU2199585C2 (et)
WO (1)	WO1996007748A1 (et)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2199585C2 (ru)	1994-09-02	2003-02-27	ГСФ-Форшунгсцентрум фюр Умвельт унд Гезундхайт ГмбХ	Ретровирусная векторная конструкция, подвергающаяся промоторной конверсии, способ введения гомологичных или гетерологичных нуклеотидных последовательностей в человеческие или животные клетки in vitro и/или in vivo, рекомбинантная ретровирусная частица, фармацевтическая композиция для генной терапии
DE69627644T2 (de)	1995-03-09	2004-02-19	GSF-Forschungszentrum für Umwelt und Gesundheit GmbH	Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
CN1187095C (zh)	1995-06-27	2005-02-02	巴法里安诺迪克有限公司	可生产病毒颗粒的被囊化细胞
EP0859854B1 (en) *	1995-10-13	2002-05-02	Austrian Nordic Biotherapeutics AG	Retroviral vectors carrying senescent cell derived inhibitors 1 (sdi-1) or antisense sdi-1 nucleotide sequences
US7074398B1 (en)	1995-10-13	2006-07-11	Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh	Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences
JP4229982B2 (ja)	1996-03-27	2009-02-25	ババリアン・ノルディック・アクティーゼルスカブ	シトクロムｐ４５０を形質導入するレトロウイルスベクター
US6540995B1 (en)	1996-03-27	2003-04-01	Bavarian Nordic Research Institute Gmbh	Encapsulated cells producing cytochrome P450
WO1998032869A1 (en) *	1997-01-29	1998-07-30	Neurosearch A/S	Expression vectors and methods for in vivo expression of therapeutic polypeptides
ATE528405T1 (de) *	1997-12-22	2011-10-15	Oxford Biomedica Ltd	Auf dem virus der infektiösen pferdeanämie (eiav) basierende vektoren
DE69920659T2 (de) *	1998-01-06	2006-03-09	Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien	Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression
FR2778670B1 (fr) *	1998-05-18	2002-12-13	Rhone Poulenc Rorer Sa	Methodes et compositions pour la production de particules virales
DE19910650A1 (de) *	1999-03-10	2000-09-21	Gsf Forschungszentrum Umwelt	Auf HERV-LTR-Sequenzen basierende retrovirale Expressionsvektoren
CA2371946A1 (en) *	1999-04-29	2000-11-09	Aarhus University	Expression of heterologous genes from an ires translational cassette in retroviral vectors
WO2002064805A2 (en) *	2001-02-09	2002-08-22	Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien	Replication competent non-mammalian retroviral vectors
DE102009021592A1 (de) *	2009-05-15	2010-11-18	Medizinische Hochschule Hannover	ASLV-Vektorsystem
CN120866241B (zh) *	2025-09-28	2026-01-30	深圳细胞谷生物医药有限公司	通过稳定细胞系生产工程化类病毒颗粒的方法及其工程化类病毒颗粒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989011539A1 (en)	1988-05-17	1989-11-30	Sloan-Kettering Institute For Cancer Research	Retroviral vector
GB8919607D0 (en) *	1989-08-30	1989-10-11	Wellcome Found	Novel entities for cancer therapy
WO1994029437A1 (en) *	1993-06-07	1994-12-22	University Of Medicine & Dentistry Of New Jersey	Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
RU2199585C2 (ru)	1994-09-02	2003-02-27	ГСФ-Форшунгсцентрум фюр Умвельт унд Гезундхайт ГмбХ	Ретровирусная векторная конструкция, подвергающаяся промоторной конверсии, способ введения гомологичных или гетерологичных нуклеотидных последовательностей в человеческие или животные клетки in vitro и/или in vivo, рекомбинантная ретровирусная частица, фармацевтическая композиция для генной терапии
DE69627644T2 (de) *	1995-03-09	2004-02-19	GSF-Forschungszentrum für Umwelt und Gesundheit GmbH	Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
EP0817859B1 (en) *	1995-03-09	2002-01-16	Austrian Nordic Biotherapeutics AG	Recombinant dna vectors for gene therapy
US6117681A (en) *	1995-03-29	2000-09-12	Bavarian Nordic Research Inst. A/S	Pseudotyped retroviral particles
GB9510272D0 (en)	1995-05-22	1995-07-19	Isis Innovation	Retroviral vectors
US7074398B1 (en) *	1995-10-13	2006-07-11	Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh	Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences

1995
- 1995-09-01 RU RU97105070/13A patent/RU2199585C2/ru not_active IP Right Cessation
- 1995-09-01 DK DK95931969T patent/DK0779929T5/da active
- 1995-09-01 MX MX9701544A patent/MX9701544A/es not_active IP Right Cessation
- 1995-09-01 ES ES95931969T patent/ES2156945T3/es not_active Expired - Lifetime
- 1995-09-01 WO PCT/EP1995/003445 patent/WO1996007748A1/en not_active Ceased
- 1995-09-01 CA CA002198210A patent/CA2198210C/en not_active Expired - Fee Related
- 1995-09-01 FI FI970892A patent/FI970892A0/fi unknown
- 1995-09-01 CN CN95194903A patent/CN1117156C/zh not_active Expired - Fee Related
- 1995-09-01 DE DE69520681T patent/DE69520681T2/de not_active Expired - Lifetime
- 1995-09-01 AT AT95931969T patent/ATE200517T1/de active
- 1995-09-01 PL PL95319033A patent/PL184375B1/pl not_active IP Right Cessation
- 1995-09-01 HU HU9701764A patent/HU221607B/hu not_active IP Right Cessation
- 1995-09-01 BR BR9508664A patent/BR9508664A/pt not_active IP Right Cessation
- 1995-09-01 NZ NZ292897A patent/NZ292897A/en not_active IP Right Cessation
- 1995-09-01 JP JP50918696A patent/JP4037446B2/ja not_active Expired - Fee Related
- 1995-09-01 EP EP95931969A patent/EP0779929B1/en not_active Expired - Lifetime
- 1995-09-01 AU AU35201/95A patent/AU688590B2/en not_active Ceased
- 1995-09-01 EE EE9700040A patent/EE03492B1/et not_active IP Right Cessation
1997
- 1997-02-27 NO NO19970902A patent/NO317731B1/no not_active IP Right Cessation
- 1997-02-28 US US08/808,827 patent/US7531353B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
BR9508664A (pt)	1998-01-06
US7531353B1 (en)	2009-05-12
CN1117156C (zh)	2003-08-06
NZ292897A (en)	1998-08-26
AU3520195A (en)	1996-03-27
FI970892L (fi)	1997-02-28
HU221607B (hu)	2002-11-28
NO970902D0 (no)	1997-02-27
ES2156945T3 (es)	2001-08-01
HK1001527A1 (en)	1998-06-26
CA2198210C (en)	2006-07-11
NO317731B1 (no)	2004-12-13
WO1996007748A1 (en)	1996-03-14
CA2198210A1 (en)	1996-03-14
HUT76974A (hu)	1998-01-28
EP0779929A1 (en)	1997-06-25
EE9700040A (et)	1997-08-15
AU688590B2 (en)	1998-03-12
NO970902L (no)	1997-04-24
DE69520681T2 (de)	2001-11-29
CN1159210A (zh)	1997-09-10
FI970892A7 (fi)	1997-02-28
EP0779929B1 (en)	2001-04-11
MX9701544A (es)	1998-03-31
ATE200517T1 (de)	2001-04-15
JPH10507628A (ja)	1998-07-28
PL319033A1 (en)	1997-07-21
PL184375B1 (pl)	2002-10-31
DE69520681D1 (de)	2001-05-17
FI970892A0 (fi)	1997-02-28
DK0779929T5 (da)	2001-08-13
RU2199585C2 (ru)	2003-02-27
JP4037446B2 (ja)	2008-01-23
DK0779929T3 (da)	2001-05-07

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2012-06-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20110901

Publication	Publication Date	Title
DK0779929T3 (da)	2001-05-07	Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer
WO1998039463A3 (en)	1999-01-07	Lentivirus based vector and vector system
TR199802695T2 (xx)	1999-04-21	IL-8 Resept�r kar��tlar�
DE69615682D1 (de)	2001-11-08	N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1-h-benzo[b][1,5]-diazepin-3-yl)-acetamide
DK0728146T3 (da)	2002-04-22	Conotoxinpeptider
EE04378B1 (et)	2004-10-15	LAG-3 pleissimisteisendid
ATE469228T1 (de)	2010-06-15	Dns, die für phosphodiesterasen von säugetieren kodiert
ES2193241T3 (es)	2003-11-01	Nuevas n-2-oxo2.3.4.5-tetrajodrp-1h-1,5-benzodiazepin-3-il)-3-amidas.
DE59509910D1 (de)	2002-01-17	Verfahren zur Herstellung von Alkylhydrogenchlorsilanen
CA2267945A1 (en)	1998-04-16	Anticonvulsant derivatives useful in treating neuropathic pain
ES2194102T3 (es)	2003-11-16	Nuevas n-(2,4-dioxo-2,3,4,5-tetrahidro-1h-1,5-benzodiazepin-3-il)-3-amidas.
DE59109072D1 (de)	1999-01-07	Klonierung der N-Methylhydantoinase
ATE171475T1 (de)	1998-10-15	Promoter vom k. lactis pyruvat-decarboxylase gen und anwendung davon
ID20153A (id)	1998-10-15	Proses polimerisasi etilena dengan adanya suatu katalis kromium oksida
MX9605731A (es)	1997-05-31	Preparacion de un catalizador de hidratacion con empleo de m(or)mxn.
IL72529A0 (en)	1984-11-30	5-substituted(1,2,4)triazolo(1,5,-c)pyrimidin-2-amines
UA20041A (uk)	1997-12-25	Біс-n,n-диметил-n-(2-гідрокси-3-бутоксипропіл) аміhоадипоілімід як латеhтhий каталізатор отвердіhhя епоксидhих композицій
UA20042A (uk)	1997-12-25	Біс-n,n-диметил-n-(2-гідрокси-3-бутоксипропіл) аміhо-ізо-фталімід як латеhтhий каталізатор отвердіhhя епоксидhих композицій
DE59109126D1 (de)	1999-06-17	N-Carbamoylsarcosin-Amidohydrolase, kloniert
MX9707249A (es)	1998-03-31	Catalizador y proceso para la hidrogenacion de olefinas o polimeros.
MX9701638A (es)	1997-09-30	Oxidos de alquilfenilbisacilfosfina y mezclas de fotoiniciador.
DE69729098D1 (de)	2004-06-17	Fluorierung von ketoamiden