DK0779929T3 - Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer - Google Patents

Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer

Info

Publication number
DK0779929T3
DK0779929T3 DK95931969T DK95931969T DK0779929T3 DK 0779929 T3 DK0779929 T3 DK 0779929T3 DK 95931969 T DK95931969 T DK 95931969T DK 95931969 T DK95931969 T DK 95931969T DK 0779929 T3 DK0779929 T3 DK 0779929T3
Authority
DK
Denmark
Prior art keywords
region
self
retroviral vectors
targeted retroviral
inactivating expression
Prior art date
Application number
DK95931969T
Other languages
English (en)
Other versions
DK0779929T5 (da
Inventor
Walter Henry Guenzburg
Robert Michael Saller
Original Assignee
Gsf Forschungszentrum Umwelt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gsf Forschungszentrum Umwelt filed Critical Gsf Forschungszentrum Umwelt
Publication of DK0779929T3 publication Critical patent/DK0779929T3/da
Application granted granted Critical
Publication of DK0779929T5 publication Critical patent/DK0779929T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Ceramic Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Traffic Control Systems (AREA)
  • Navigation (AREA)
  • Molds, Cores, And Manufacturing Methods Thereof (AREA)
  • Road Signs Or Road Markings (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Electrotherapy Devices (AREA)
DK95931969T 1994-09-02 1995-09-01 Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer DK0779929T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK101794 1994-09-02
PCT/EP1995/003445 WO1996007748A1 (en) 1994-09-02 1995-09-01 Non self-inactivating, expression targeted retroviral vectors

Publications (2)

Publication Number Publication Date
DK0779929T3 true DK0779929T3 (da) 2001-05-07
DK0779929T5 DK0779929T5 (da) 2001-08-13

Family

ID=8100062

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95931969T DK0779929T5 (da) 1994-09-02 1995-09-01 Ikke-selvinaktiverende, ekspressionsmålrettede retrovirale vektorer

Country Status (20)

Country Link
US (1) US7531353B1 (da)
EP (1) EP0779929B1 (da)
JP (1) JP4037446B2 (da)
CN (1) CN1117156C (da)
AT (1) ATE200517T1 (da)
AU (1) AU688590B2 (da)
BR (1) BR9508664A (da)
CA (1) CA2198210C (da)
DE (1) DE69520681T2 (da)
DK (1) DK0779929T5 (da)
EE (1) EE03492B1 (da)
ES (1) ES2156945T3 (da)
FI (1) FI970892L (da)
HU (1) HU221607B (da)
MX (1) MX9701544A (da)
NO (1) NO317731B1 (da)
NZ (1) NZ292897A (da)
PL (1) PL184375B1 (da)
RU (1) RU2199585C2 (da)
WO (1) WO1996007748A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4037446B2 (ja) 1994-09-02 2008-01-23 ゲーエスエフ − フォルシュンクスツェントルム・フューア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 非自己不活化性の発現標的化レトロウイルスベクタ
WO1996028563A1 (en) * 1995-03-09 1996-09-19 Bavarian Nordic Vectors carrying therapeutic genes encoding antimicrobial peptides for gene therapy
ATE309000T1 (de) 1995-06-27 2005-11-15 Bavarian Nordic As Verkapselte zellen die virenpartikeln produzieren
DK0859854T3 (da) * 1995-10-13 2002-08-19 Gsf Forschungszentrum Umwelt Retrovirale vektorer bærende aldrende celle-afledte inhibitorer 1 (SDI-1) eller antisense SDI-1 nukleotidsekvenser
US7074398B1 (en) 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences
SI0892852T1 (sl) 1996-03-27 2006-04-30 Bavarian Nordic As Inkapsulirane celice, ki eksprimirajo citokrom P450 za aktiviranje predzdravila
US6540995B1 (en) 1996-03-27 2003-04-01 Bavarian Nordic Research Institute Gmbh Encapsulated cells producing cytochrome P450
WO1998032869A1 (en) * 1997-01-29 1998-07-30 Neurosearch A/S Expression vectors and methods for in vivo expression of therapeutic polypeptides
ES2373406T3 (es) * 1997-12-22 2012-02-03 Oxford Biomedica (Uk) Limited Vectores basados en el virus de la anemia infecciosa equina (vaie).
ATE278029T1 (de) 1998-01-06 2004-10-15 Inst Virologie Teilrechtsfaehi Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression
FR2778670B1 (fr) * 1998-05-18 2002-12-13 Rhone Poulenc Rorer Sa Methodes et compositions pour la production de particules virales
DE19910650A1 (de) * 1999-03-10 2000-09-21 Gsf Forschungszentrum Umwelt Auf HERV-LTR-Sequenzen basierende retrovirale Expressionsvektoren
EP1173597A1 (en) * 1999-04-29 2002-01-23 Aarhus University Expression of heterologous genes from an ires translational cassette in retroviral vectors
WO2002064805A2 (en) * 2001-02-09 2002-08-22 Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien Replication competent non-mammalian retroviral vectors
DE102009021592A1 (de) * 2009-05-15 2010-11-18 Medizinische Hochschule Hannover ASLV-Vektorsystem
CN120866241B (zh) * 2025-09-28 2026-01-30 深圳细胞谷生物医药有限公司 通过稳定细胞系生产工程化类病毒颗粒的方法及其工程化类病毒颗粒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02504344A (ja) 1988-05-17 1990-12-13 スローン‐ケツテリング・インステイテユート・フオー・キヤンサー・リサーチ レトロウイルスベクター
GB8919607D0 (en) * 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
WO1994029437A1 (en) * 1993-06-07 1994-12-22 University Of Medicine & Dentistry Of New Jersey Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
JP4037446B2 (ja) 1994-09-02 2008-01-23 ゲーエスエフ − フォルシュンクスツェントルム・フューア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 非自己不活化性の発現標的化レトロウイルスベクタ
WO1996028563A1 (en) * 1995-03-09 1996-09-19 Bavarian Nordic Vectors carrying therapeutic genes encoding antimicrobial peptides for gene therapy
ES2171657T3 (es) * 1995-03-09 2002-09-16 Austrian Nordic Biotherapeutic Vector de dna recombinante para terapia genica.
US6117681A (en) * 1995-03-29 2000-09-12 Bavarian Nordic Research Inst. A/S Pseudotyped retroviral particles
GB9510272D0 (en) 1995-05-22 1995-07-19 Isis Innovation Retroviral vectors
US7074398B1 (en) * 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences

Also Published As

Publication number Publication date
CA2198210A1 (en) 1996-03-14
EP0779929B1 (en) 2001-04-11
DE69520681T2 (de) 2001-11-29
BR9508664A (pt) 1998-01-06
FI970892A7 (fi) 1997-02-28
ATE200517T1 (de) 2001-04-15
PL184375B1 (pl) 2002-10-31
CN1159210A (zh) 1997-09-10
EE03492B1 (et) 2001-08-15
DK0779929T5 (da) 2001-08-13
CN1117156C (zh) 2003-08-06
AU3520195A (en) 1996-03-27
DE69520681D1 (de) 2001-05-17
HK1001527A1 (en) 1998-06-26
FI970892A0 (fi) 1997-02-28
EP0779929A1 (en) 1997-06-25
JPH10507628A (ja) 1998-07-28
ES2156945T3 (es) 2001-08-01
NO317731B1 (no) 2004-12-13
HU221607B (hu) 2002-11-28
NO970902L (no) 1997-04-24
HUT76974A (hu) 1998-01-28
FI970892L (fi) 1997-02-28
AU688590B2 (en) 1998-03-12
US7531353B1 (en) 2009-05-12
CA2198210C (en) 2006-07-11
RU2199585C2 (ru) 2003-02-27
EE9700040A (et) 1997-08-15
NO970902D0 (no) 1997-02-27
NZ292897A (en) 1998-08-26
WO1996007748A1 (en) 1996-03-14
PL319033A1 (en) 1997-07-21
MX9701544A (es) 1998-03-31
JP4037446B2 (ja) 2008-01-23

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