EE03608B1 - Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid - Google Patents

Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Info

Publication number
EE03608B1
EE03608B1 EE9700315A EE9700315A EE03608B1 EE 03608 B1 EE03608 B1 EE 03608B1 EE 9700315 A EE9700315 A EE 9700315A EE 9700315 A EE9700315 A EE 9700315A EE 03608 B1 EE03608 B1 EE 03608B1
Authority
EE
Estonia
Prior art keywords
taxoids
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
EE9700315A
Other languages
English (en)
Estonian (et)
Other versions
EE9700315A (et
Inventor
Bouchard Herv
Bourzat Jean-Dominique
Commer�on Alain
Original Assignee
Rh�Ne-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9503545A external-priority patent/FR2732340B1/fr
Priority claimed from FR9515381A external-priority patent/FR2742754B1/fr
Application filed by Rh�Ne-Poulenc Rorer S.A. filed Critical Rh�Ne-Poulenc Rorer S.A.
Publication of EE9700315A publication Critical patent/EE9700315A/xx
Publication of EE03608B1 publication Critical patent/EE03608B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EE9700315A 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid EE03608B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9503545A FR2732340B1 (fr) 1995-03-27 1995-03-27 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR9515381A FR2742754B1 (fr) 1995-12-22 1995-12-22 Procede de preparation de taxoides
PCT/FR1996/000440 WO1996030355A1 (fr) 1995-03-27 1996-03-25 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
EE9700315A EE9700315A (et) 1998-06-15
EE03608B1 true EE03608B1 (et) 2002-02-15

Family

ID=26231838

Family Applications (2)

Application Number Title Priority Date Filing Date
EE9700315A EE03608B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid
EE9700323A EE03609B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Family Applications After (1)

Application Number Title Priority Date Filing Date
EE9700323A EE03609B1 (et) 1995-03-27 1996-03-25 Taksoidid, meetod nende valmistamiseks ja neid sisaldavad farmatseutilised kompositsioonid

Country Status (41)

Country Link
US (3) US5889043A (de)
EP (2) EP0817779B1 (de)
JP (2) JP3790826B2 (de)
KR (2) KR100485309B1 (de)
CN (2) CN1213042C (de)
AP (2) AP785A (de)
AR (1) AR001440A1 (de)
AT (2) ATE188471T1 (de)
AU (2) AU711227B2 (de)
BG (2) BG63009B1 (de)
BR (2) BR9607929A (de)
CA (2) CA2214319C (de)
CO (1) CO4700576A1 (de)
CZ (2) CZ287326B6 (de)
DE (2) DE69604653T2 (de)
DK (2) DK0817779T3 (de)
DZ (1) DZ2009A1 (de)
EA (2) EA000709B1 (de)
EE (2) EE03608B1 (de)
ES (2) ES2143187T3 (de)
GE (2) GEP20002211B (de)
GR (2) GR3031526T3 (de)
HU (2) HU223666B1 (de)
IL (1) IL117636A (de)
IS (2) IS2058B (de)
MA (1) MA23823A1 (de)
MY (1) MY121225A (de)
NO (2) NO316607B1 (de)
NZ (2) NZ304900A (de)
OA (2) OA10514A (de)
PE (1) PE51097A1 (de)
PL (2) PL188284B1 (de)
PT (1) PT817779E (de)
RO (2) RO115878B1 (de)
SK (2) SK281927B6 (de)
TN (1) TNSN96043A1 (de)
TR (2) TR199701040T1 (de)
TW (1) TW394765B (de)
UY (2) UY24192A1 (de)
WO (2) WO1996030355A1 (de)
ZA (1) ZA962399B (de)

Families Citing this family (79)

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US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US5811452A (en) * 1997-01-08 1998-09-22 The Research Foundation Of State University Of New York Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
FR2771092B1 (fr) * 1997-11-18 1999-12-17 Rhone Poulenc Rorer Sa Procede de preparation de derives de la classe des taxoides
EP0982027A1 (de) * 1998-08-17 2000-03-01 Aventis Pharma S.A. Taxoid-Derivaten zur Behandlung von abnormaler Zellvermehrung des Gehirns
US6346543B1 (en) * 1998-08-17 2002-02-12 Aventis Pharma S.A. Use of a taxoid to treat abnormal cell proliferation in the brain
KR20010079665A (ko) * 1998-08-20 2001-08-22 추후제출 탁소이드 유도체의 신규 용도
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EP1020188A1 (de) * 1999-01-13 2000-07-19 Aventis Pharma S.A. Neue Verwendung von Taxoid-Derivaten
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
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US6593334B1 (en) 2002-05-02 2003-07-15 The University Of North Carolina At Chapel Hill Camptothecin-taxoid conjugates as antimitotic and antitumor agents
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US7064980B2 (en) * 2003-09-17 2006-06-20 Sandisk Corporation Non-volatile memory and method with bit line coupled compensation
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JP2008530122A (ja) * 2005-02-14 2008-08-07 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ１０シクロプロピルエステル置換タキサン組成物
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EP2620148A1 (de) 2012-01-27 2013-07-31 Aventis Pharma S.A. Antitumorkombination mit Cabazitaxel und Cisplatin
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CN103764637A (zh) * 2011-04-12 2014-04-30 普拉斯化学品有限公司 卡巴他赛的固态形式及其制备方法
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CN102603724B (zh) * 2011-10-20 2014-02-26 江苏红豆杉生物科技股份有限公司 二甲氧基紫杉烷类化合物纯化精制的方法
CN102424672A (zh) * 2011-10-20 2012-04-25 江苏红豆杉生物科技有限公司 脱保护基制备二甲氧基紫杉烷类化合物的方法
CN102516281B (zh) * 2011-10-20 2015-02-04 江苏红豆杉生物科技股份有限公司 一种10-脱乙酰基巴卡丁iii及其衍生物甲氧基化的方法
CN103906747A (zh) * 2011-10-31 2014-07-02 台湾神隆股份有限公司 卡巴他赛及其中间体的制备方法
CN102417491B (zh) * 2011-10-31 2013-11-06 江苏红豆杉生物科技有限公司 以10-去乙酰基-巴卡丁iii为原料制备卡巴他赛的方法
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CN102775434B (zh) * 2012-08-21 2015-04-08 江苏红豆杉生物科技股份有限公司 一种7,10-二甲氧基紫杉烷化合物中间体的合成方法
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KR101407353B1 (ko) * 2012-12-04 2014-06-17 주식회사 삼양바이오팜 10-디아세틸바카틴 iii으로부터 카바지탁셀을 고수율로 제조하는 새로운 방법 및 이를 위한 신규 중간체
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EP2815749A1 (de) 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Feste Form von 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dion mit spezifischem Röntgenbeugungsspektrum
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CN104650012A (zh) * 2013-11-22 2015-05-27 天士力控股集团有限公司 一种紫杉烷类化合物
CN104086514A (zh) * 2014-06-19 2014-10-08 上海应用技术学院 紫杉醇衍生物及其制备方法
JP6841772B2 (ja) 2015-02-17 2021-03-10 エラスムス・ユニヴァーシティ・メディカル・センター・ロッテルダム 前立腺癌の処置におけるカバジタキセルの使用
EP3093014A1 (de) * 2015-05-13 2016-11-16 Aventis Pharma S.A. Cabazitaxel und dessen verwendung zur behandlung von krebs
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TWI857119B (zh) 2019-08-08 2024-10-01 香港商來凱有限公司 治療癌症之方法
EP3797834A1 (de) 2019-09-25 2021-03-31 Sanofi Mature IP Cabazitaxel in mcrc-patienten, die zuvor mit docetaxel behandelt wurden und bei denen ein vorheriger, auf androgensignalisierung abzielender inhibitor versagt hat
EP3808345A1 (de) 2019-10-15 2021-04-21 Sanofi Mature IP Cabazitaxel bei mcrc-patienten, die zuvor mit docetaxel behandelt wurden und bei denen ein vorheriger, auf androgensignalisierung abzielender inhibitor versagt hat
WO2026064520A1 (en) 2024-09-19 2026-03-26 Tesseract Medicines Us, Llc Covalent-induced drug conjugates targeting kras and comprising a tubulin inhibitor payload
WO2026064527A1 (en) 2024-09-19 2026-03-26 Tesseract Medicines Us, Llc Kras-targeting covalent-induced drug conjugates comprising a tubulin inhibitor payload

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MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
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Also Published As

Publication number Publication date
HUP9801204A1 (hu) 2000-05-28
CN1152870C (zh) 2004-06-09
AP9701090A0 (en) 1997-10-31
JPH11500141A (ja) 1999-01-06
AU703278B2 (en) 1999-03-25
CA2214319C (fr) 2004-02-17
CZ303297A3 (cs) 1998-01-14
DE69604653D1 (de) 1999-11-18
IS4567A (is) 1997-09-23
DE69604653T2 (de) 2000-05-31
UY24370A1 (es) 2001-10-25
MX9706278A (es) 1997-10-31
HU223666B1 (hu) 2004-11-29
MX9706568A (es) 1997-11-29
BG101918A (en) 1998-10-30
EA000567B1 (ru) 1999-12-29
IS2058B (is) 2005-10-14
IS2056B (is) 2005-10-14
US20020038038A1 (en) 2002-03-28
NZ304901A (en) 1998-12-23
BR9607929A (pt) 1998-06-02
BG63121B1 (bg) 2001-04-30
AP785A (en) 1999-11-26
WO1996030355A1 (fr) 1996-10-03
IL117636A0 (en) 1996-07-23
CA2214321A1 (fr) 1996-10-03
KR100297196B1 (ko) 2001-11-22
AU5278096A (en) 1996-10-16
CA2214321C (fr) 2008-01-22
US6331635B1 (en) 2001-12-18
HUP9801201A2 (hu) 2000-05-28
MA23823A1 (fr) 1996-10-01
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US6387946B1 (en) 2002-05-14
EE9700323A (et) 1998-06-15
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IS4536A (is) 1997-07-31
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PT817779E (pt) 2000-04-28
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BR9607930A (pt) 1998-06-02
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MY121225A (en) 2006-01-28
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