EE03662B1 - Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse - Google Patents

Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse

Info

Publication number: EE03662B1
Authority: EE; Estonia
Prior art keywords: composition; pct; ratio; hydrophilic polymer; ion
Prior art date: 1994-03-31

Application number

EE9600157A

Other languages

English (en)

Other versions

EE9600157A (et

Inventor

Lehmussaari Kari

Vartiainen Eija

Reunam�ki Timo

Oksala Olli

Alaranta Sakari

Pohjala Esko

Original Assignee

Leiras Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-31

Filing date

1995-03-29

Publication date

2002-04-15

1995-03-29 Application filed by Leiras Oy filed Critical Leiras Oy

1997-06-16 Publication of EE9600157A publication Critical patent/EE9600157A/et

2002-04-15 Publication of EE03662B1 publication Critical patent/EE03662B1/et

Links

239000000203 mixture Substances 0.000 title abstract 4
229920001477 hydrophilic polymer Polymers 0.000 title abstract 2
229910017053 inorganic salt Inorganic materials 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 3
229920000642 polymer Polymers 0.000 abstract 2
239000000243 solution Substances 0.000 abstract 2
238000010521 absorption reaction Methods 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000000872 buffer Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003755 preservative agent Substances 0.000 abstract 1
230000002335 preservative effect Effects 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1
239000000080 wetting agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Inorganic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EE9600157A 1994-03-31 1995-03-29 Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse EE03662B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9401109A SE9401109D0 (sv)	1994-03-31	1994-03-31	Opthalmic composition II
PCT/FI1995/000167 WO1995026712A1 (en)	1994-03-31	1995-03-29	Ophthalmic composition containing an ion sensitive, hydrophilic polymer and an inorganic salt in a ratio which gives low viscosity

Publications (2)

Publication Number	Publication Date
EE9600157A EE9600157A (et)	1997-06-16
EE03662B1 true EE03662B1 (et)	2002-04-15

Family

ID=20393512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9600157A EE03662B1 (et)	1994-03-31	1995-03-29	Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse

Country Status (25)

Country	Link
US (1)	US5795913A (et)
EP (1)	EP0755246B1 (et)
JP (1)	JPH10503471A (et)
KR (1)	KR970702025A (et)
CN (1)	CN1114399C (et)
AT (1)	ATE220538T1 (et)
AU (1)	AU694498B2 (et)
BG (1)	BG63144B1 (et)
BR (1)	BR9507439A (et)
CA (1)	CA2186591A1 (et)
CZ (1)	CZ286496A3 (et)
DE (2)	DE69527422T2 (et)
DK (1)	DK0755246T3 (et)
EE (1)	EE03662B1 (et)
ES (1)	ES2179871T3 (et)
HU (1)	HU223070B1 (et)
MX (1)	MX9603919A (et)
NO (1)	NO314435B1 (et)
PL (1)	PL316585A1 (et)
PT (1)	PT755246E (et)
RO (1)	RO115410B1 (et)
RU (1)	RU2157194C2 (et)
SE (1)	SE9401109D0 (et)
SK (1)	SK281473B6 (et)
WO (1)	WO1995026712A1 (et)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY116782A (en)	1997-12-22	2004-03-31	Otsuka Pharma Co Ltd	Water-soluble eye drop
AU4808000A (en)	1999-04-28	2000-11-10	Situs Corporation	Drug delivery system
AT407482B (de) *	1999-05-10	2001-03-26	Armin Dr Ettl	Kalziumantagonistische augentropfen zur prophylaktischen behandlung der cataract
US6218428B1 (en)	2000-04-28	2001-04-17	Emil Chynn	Ophthalmic composition
MXPA04008171A (es) *	2002-02-22	2004-11-26	Pharmacia Corp	Formulacion oftalmica con sistema de goma.
US7030149B2 (en)	2002-04-19	2006-04-18	Allergan, Inc.	Combination of brimonidine timolol for topical ophthalmic use
AU2003252746A1 (en)	2002-07-31	2004-02-16	Senju Pharmaceutical Co., Ltd.	Aqueous liquid preparations and light-stabilized aqueous liquid preparations
US8877168B1 (en)	2002-07-31	2014-11-04	Senju Pharmaceuticals Co., Ltd.	Aqueous liquid preparations and light-stabilized aqueous liquid preparations
US7862552B2 (en)	2005-05-09	2011-01-04	Boston Scientific Scimed, Inc.	Medical devices for treating urological and uterine conditions
DE102005035986B4 (de) *	2005-07-28	2009-10-15	Bausch & Lomb Incorporated	Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat
US20080057022A1 (en) *	2006-08-30	2008-03-06	Erning Xia	Ophthalmic Pharmaceutical Compositions and Uses Thereof
US9522153B2 (en)	2009-12-22	2016-12-20	Allergan, Inc.	Compositions and methods for lowering intraocular pressure
IL212725A (en) *	2011-05-05	2016-06-30	Resdevco Res And Dev Co	Glycerol Preparation for Non-surgical Conjunctivochalysis
WO2017035408A1 (en)	2015-08-26	2017-03-02	Achillion Pharmaceuticals, Inc.	Compounds for treatment of immune and inflammatory disorders
AR106018A1 (es)	2015-08-26	2017-12-06	Achillion Pharmaceuticals Inc	Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
CN109790143A (zh)	2016-05-10	2019-05-21	C4医药公司	用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体
EP3463344A4 (en) *	2016-06-01	2020-02-12	Harold Richard Hellstrom	TREATMENT OF DRY EYE WITH PARASYMPATHIC AND ANTISYMPATHIC AGENTS
SG11201811491YA (en)	2016-06-27	2019-01-30	Achillion Pharmaceuticals Inc	Quinazoline and indole compounds to treat medical disorders
PT3500255T (pt)	2016-08-19	2023-01-10	Orasis Pharmaceuticals Ltd	Composições farmacêuticas oftálmicas e utilizações relacionadas com estas
CN110603252A (zh)	2017-03-01	2019-12-20	艾其林医药公司	用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
CN110769822A (zh)	2017-06-20	2020-02-07	C4医药公司	用于蛋白降解的n/o-连接的降解决定子和降解决定子体
EP3773576A4 (en)	2018-03-26	2021-12-29	C4 Therapeutics, Inc.	Cereblon binders for the degradation of ikaros
PL3681500T3 (pl) *	2018-04-24	2022-08-01	Allergan, Inc.	Zastosowanie chlorowodorku pilokarpiny w leczeniu starczowzroczności
US20230022157A1 (en)	2018-08-20	2023-01-26	Achillion Pharmaceuticals, Inc.	Pharmaceutical compounds for the treatment of complement factor d medical disorders
JP7443375B2 (ja)	2018-09-06	2024-03-05	アキリオンファーマシューティカルズ，インコーポレーテッド	医学的障害の治療のための大環状化合物
EP3866773B1 (en)	2018-10-16	2024-08-28	Georgia State University Research Foundation, Inc.	Carbon monoxide prodrugs for the treatment of medical disorders
WO2020210630A1 (en)	2019-04-12	2020-10-15	C4 Therapeutics, Inc.	Tricyclic degraders of ikaros and aiolos
CN115362162A (zh)	2020-02-20	2022-11-18	艾其林医药公司	用于治疗补体因子d介导的障碍的杂芳基化合物
TW202146412A (zh)	2020-03-05	2021-12-16	美商Ｃ４醫藥公司	用於標靶降解brd9之化合物
CN116437913A (zh)	2020-09-23	2023-07-14	艾其林医药公司	用于治疗补体介导的病症的药物化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6056684B2 (ja) *	1977-11-07	1985-12-11	東興薬品工業株式会社	点眼剤
GB2169508B (en) *	1985-01-11	1989-02-01	Smith & Nephew Ass	Ophthalmic compositions and use
US5252318A (en) *	1990-06-15	1993-10-12	Allergan, Inc.	Reversible gelation compositions and methods of use
FR2678832B1 (fr) *	1991-07-10	1995-03-17	Europhta Sa Laboratoire	Nouvelles compositions ophtalmiques a resorption amelioree et leurs procedes de preparation.
RU2007152C1 (ru) *	1992-10-01	1994-02-15	Курский Государственный Медицинский Институт	Офтальмологическое средство и способ его получения

1994
- 1994-03-31 SE SE9401109A patent/SE9401109D0/xx unknown
1995
- 1995-03-29 HU HU9602692A patent/HU223070B1/hu not_active IP Right Cessation
- 1995-03-29 RU RU96119922/14A patent/RU2157194C2/ru not_active IP Right Cessation
- 1995-03-29 EE EE9600157A patent/EE03662B1/et not_active IP Right Cessation
- 1995-03-29 US US08/535,033 patent/US5795913A/en not_active Expired - Fee Related
- 1995-03-29 EP EP95914363A patent/EP0755246B1/en not_active Expired - Lifetime
- 1995-03-29 DE DE69527422T patent/DE69527422T2/de not_active Expired - Fee Related
- 1995-03-29 CA CA002186591A patent/CA2186591A1/en not_active Abandoned
- 1995-03-29 SK SK1238-96A patent/SK281473B6/sk unknown
- 1995-03-29 JP JP7525424A patent/JPH10503471A/ja active Pending
- 1995-03-29 PT PT95914363T patent/PT755246E/pt unknown
- 1995-03-29 DK DK95914363T patent/DK0755246T3/da active
- 1995-03-29 RO RO96-01878A patent/RO115410B1/ro unknown
- 1995-03-29 CZ CZ962864A patent/CZ286496A3/cs unknown
- 1995-03-29 CN CN95192184A patent/CN1114399C/zh not_active Expired - Fee Related
- 1995-03-29 BR BR9507439A patent/BR9507439A/pt not_active IP Right Cessation
- 1995-03-29 KR KR1019960705392A patent/KR970702025A/ko not_active Withdrawn
- 1995-03-29 ES ES95914363T patent/ES2179871T3/es not_active Expired - Lifetime
- 1995-03-29 WO PCT/FI1995/000167 patent/WO1995026712A1/en not_active Ceased
- 1995-03-29 AU AU21390/95A patent/AU694498B2/en not_active Ceased
- 1995-03-29 AT AT95914363T patent/ATE220538T1/de not_active IP Right Cessation
- 1995-03-29 MX MX9603919A patent/MX9603919A/es not_active IP Right Cessation
- 1995-03-29 DE DE0755246T patent/DE755246T1/de active Pending
- 1995-03-29 PL PL95316585A patent/PL316585A1/xx unknown
1996
- 1996-09-27 NO NO19964071A patent/NO314435B1/no unknown
- 1996-10-16 BG BG100914A patent/BG63144B1/bg unknown

Also Published As

Publication number	Publication date
SE9401109D0 (sv)	1994-03-31
EE9600157A (et)	1997-06-16
PL316585A1 (en)	1997-01-20
HU223070B1 (hu)	2004-03-01
BR9507439A (pt)	1997-09-16
PT755246E (pt)	2002-11-29
CZ286496A3 (en)	1997-03-12
RO115410B1 (ro)	2000-02-28
JPH10503471A (ja)	1998-03-31
BG63144B1 (bg)	2001-05-31
HU9602692D0 (en)	1996-11-28
SK281473B6 (sk)	2001-04-09
MX9603919A (es)	1997-04-30
US5795913A (en)	1998-08-18
CN1144476A (zh)	1997-03-05
EP0755246A1 (en)	1997-01-29
DE69527422D1 (de)	2002-08-22
AU694498B2 (en)	1998-07-23
BG100914A (en)	1997-07-31
NO314435B1 (no)	2003-03-24
ES2179871T3 (es)	2003-02-01
SK123896A3 (en)	1997-06-04
NO964071L (no)	1996-11-22
DE755246T1 (de)	1997-09-04
DE69527422T2 (de)	2003-03-20
CN1114399C (zh)	2003-07-16
EP0755246B1 (en)	2002-07-17
CA2186591A1 (en)	1995-10-12
RU2157194C2 (ru)	2000-10-10
DK0755246T3 (da)	2002-11-04
WO1995026712A1 (en)	1995-10-12
KR970702025A (ko)	1997-05-13
AU2139095A (en)	1995-10-23
HUT75664A (en)	1997-05-28
ATE220538T1 (de)	2002-08-15
NO964071D0 (no)	1996-09-27

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2006-12-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20060329

Publication	Publication Date	Title
EE03662B1 (et)	2002-04-15	Oftalmoloogiline kompositsioon, mis sisaldab ioontundlikku hüdrofiilset polümeeri ja anorgaanilist soola vahekorras, mis tagab kompositsiooni madala viskoossuse
BR9507438A (pt)	1997-09-16	Composição oftálmica com viscosidade reduzida
US4440662A (en)	1984-04-03	Cleaning composition for contact lenses
US5591426A (en)	1997-01-07	Ophthalmic solution for artificial tears
US5945121A (en)	1999-08-31	Liposome eye drops
KR960700081A (ko)	1996-01-19	콘택트렌즈 용액 보존 시스템(preservative system for contact lens solutions)
BR9815009A (pt)	2000-10-03	Composições de múltiplas finalidades para o cuidado de lentes de contato.
BR9914128A (pt)	2002-09-24	Composições antibióticas para tratamento do olho, ouvido e nariz
GB2121555A (en)	1983-12-21	A soft contact lens preserving preparation
DE69824326D1 (de)	2004-07-15	Pharmazeutische Emulsion enthaltend Sorbinsäure, Na-EDTA und Borsäure
WO2008036855A2 (en)	2008-03-27	Self-preserved aqueous pharmaceutical compositions
WO2009006130A2 (en)	2009-01-08	Salt free hyaluronate ophthalmic solution
DE3625867C2 (de)	1995-10-19	Verwendung von Tetrachlordecaoxid in der Ophthalmologie
KR20210011187A (ko)	2021-02-01	클로르헥시딘 또는 이의 유도체를 포함하는 항균 지속성이 개선된 수용성 소독용 조성물 및 이를 포함하는 섬유형 소독제
JPS6452727A (en)	1989-02-28	Antiallergic eye drop
AU2001242398A1 (en)	2001-08-27	Contact lens treating method and composition
IE913021A1 (en)	1992-03-11	Nor-statine and nor-cyclostatine polypeptides in the¹treatment of ocular hypertension and glaucoma