EE04567B1 - Crystalline Monoh Drape, Method for its preparation and its use in the manufacture of a medicament - Google Patents

Crystalline Monoh Drape, Method for its preparation and its use in the manufacture of a medicament

Info

Publication number: EE04567B1
Authority: EE; Estonia
Prior art keywords: monoh; drape; medicament; crystalline; manufacture
Prior art date: 2000-10-12

Application number

EEP200300171A

Other languages

Estonian (et)

Inventor

Banholzer Rolf

Sieger Peter

Kulinna Christian

Trunk Michael

Ludwig August Graulich Manfred

Specht Peter

Meissner Helmut

Mathes Andreas

Original Assignee

Boehringer Ingelheim Pharma Gmbh & Co. Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-12

Filing date

2001-09-28

Publication date

2005-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE04567(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-09-28 Application filed by Boehringer Ingelheim Pharma Gmbh & Co. Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co. Kg

2003-06-16 Publication of EE200300171A publication Critical patent/EE200300171A/en

2005-12-15 Publication of EE04567B1 publication Critical patent/EE04567B1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EEP200300171A 2000-10-12 2001-09-28 Crystalline Monoh Drape, Method for its preparation and its use in the manufacture of a medicament EE04567B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10050621		2000-10-12
PCT/EP2001/011225 WO2002030928A1 (en)	2000-10-12	2001-09-28	Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Publications (2)

Publication Number	Publication Date
EE200300171A EE200300171A (en)	2003-06-16
EE04567B1 true EE04567B1 (en)	2005-12-15

Family

ID=7659568

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300171A EE04567B1 (en)	2000-10-12	2001-09-28	Crystalline Monoh Drape, Method for its preparation and its use in the manufacture of a medicament

Country Status (46)

Country	Link
EP (2)	EP1326862B1 (en)
JP (1)	JP3764422B2 (en)
KR (1)	KR100823860B1 (en)
CN (2)	CN1221549C (en)
AP (1)	AP1572A (en)
AR (2)	AR034389A1 (en)
AT (1)	ATE276253T1 (en)
AU (2)	AU1499602A (en)
BG (1)	BG66161B1 (en)
BR (1)	BR0114584A (en)
CA (1)	CA2425539C (en)
CR (1)	CR6938A (en)
CZ (1)	CZ301841B6 (en)
DE (1)	DE50103666D1 (en)
DK (1)	DK1326862T3 (en)
DZ (1)	DZ3478A1 (en)
EA (1)	EA004381B1 (en)
EC (1)	ECSP034540A (en)
EE (1)	EE04567B1 (en)
EG (1)	EG24142A (en)
ES (1)	ES2228965T3 (en)
GE (1)	GEP20063905B (en)
HR (1)	HRP20030276B1 (en)
HU (1)	HU226830B1 (en)
IL (2)	IL155335A0 (en)
IS (1)	IS2339B (en)
MA (1)	MA25842A1 (en)
ME (2)	ME00243B (en)
MX (1)	MXPA03003221A (en)
MY (1)	MY126931A (en)
NO (1)	NO328465B1 (en)
NZ (1)	NZ525733A (en)
OA (1)	OA12403A (en)
PE (1)	PE20020422A1 (en)
PL (1)	PL207870B1 (en)
PT (1)	PT1326862E (en)
RS (1)	RS50218B (en)
SA (1)	SA01220412B1 (en)
SI (1)	SI1326862T1 (en)
SK (1)	SK287009B6 (en)
TR (1)	TR200402579T4 (en)
TW (1)	TW589313B (en)
UA (1)	UA74215C2 (en)
UY (2)	UY26962A1 (en)
WO (1)	WO2002030928A1 (en)
ZA (1)	ZA200302500B (en)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ME00412B (en) *	2001-06-22	2011-10-10	Boehringer Ingelheim Pharma	CRYSTALLINE ANTICHOLINERGICUM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN THE MANUFACTURE OF A MEDICAMENT
US6608055B2 (en)	2001-06-22	2003-08-19	Boehringer Ingelheim Pharma Kg	Crystalline anticholinergic, processes for preparing it and its use for preparing a pharmaceutical composition
DE10212264A1 (en)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Crystalline micronisate, process for its preparation and its use for the manufacture of a medicament
US7311894B2 (en)	2002-03-28	2007-12-25	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations containing an anticholinergic
DE10214263A1 (en) *	2002-03-28	2003-10-16	Boehringer Ingelheim Pharma	HFA suspension formulations containing an anticholinergic
US7244415B2 (en)	2002-03-28	2007-07-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	HFA suspension formulations of an anhydrate
US7056916B2 (en)	2002-11-15	2006-06-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Medicaments for the treatment of chronic obstructive pulmonary disease
DE10317461A1 (en)	2003-04-16	2004-10-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Preparing microparticles labeled with technetium, useful as powders for inhalation, e.g. to study deposition of pharmaceuticals, such as anticholinergic agents, involves incubation with solution of technetium salt
JP5165244B2 (en)	2003-11-03	2013-03-21	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Method for producing tiotropium salt, tiotropium salt and pharmaceutical composition containing the same
DK2083007T3 (en) *	2003-11-03	2013-07-29	Boehringer Ingelheim Int	Tiotropium salts, processes for their preparation, and drug formulations containing them
US7968717B2 (en)	2003-11-03	2011-06-28	Boehringer Ingelhein International Gmbh	Crystalline anhydrate with anticholinergic efficacy
ME00349B (en) *	2003-11-03	2011-05-10	Boehringer Ingelheim Int	NEW CRYSTALLINE ANHYDRATE WITH ANTICHOLINERGER EFFICACY
DE102004016179A1 (en) *	2004-03-30	2005-10-20	Boehringer Ingelheim Pharma	Compounds for the treatment of proliferative processes
DK2422786T3 (en)	2004-04-22	2014-11-17	Boehringer Ingelheim Int	New drug combinations for the treatment of respiratory diseases
DE102004024454A1 (en)	2004-05-14	2005-12-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Novel enantiomerically pure beta agonists, process for their preparation and their use as pharmaceuticals
US7220742B2 (en)	2004-05-14	2007-05-22	Boehringer Ingelheim International Gmbh	Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
ES2322148T3 (en)	2004-08-11	2009-06-17	BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG	MEDICINES CONTAINING ANTI-POLINERGIC FOR TREATMENT IN URINARY ROADS.
US20060079544A1 (en) *	2004-08-13	2006-04-13	Boehringer Ingelheim International Gmbh	Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
DE102004048389A1 (en)	2004-10-01	2006-04-06	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Modification of surfaces of lactose as adjuvant for use with powder inhalants
EA013776B1 (en) *	2004-10-21	2010-06-30	Бёрингер Ингельхайм Интернациональ Гмбх	Blister for inhalers
CA2600636A1 (en) *	2005-03-09	2006-09-14	Boehringer Ingelheim International Gmbh	New pharmaceutical compositions based on anticholinergics and pde 5-inhibitors
JP5053997B2 (en)	2005-04-28	2012-10-24	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Novel compounds for the treatment of inflammatory diseases
JP2008540367A (en) *	2005-05-02	2008-11-20	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	New crystalline tiotropium bromide
WO2006117299A2 (en)	2005-05-02	2006-11-09	Boehringer Ingelheim International Gmbh	Novel crystalline forms of tiotropium bromide
NZ564697A (en) *	2005-06-15	2010-04-30	Boehringer Ingelheim Int	Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof
DE102005030733A1 (en)	2005-07-01	2007-01-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New drug combinations for the treatment of respiratory diseases containing long-acting beta-2 agonists and at least one other active ingredient
EP1915158A1 (en) *	2005-08-06	2008-04-30	Boehringer Ingelheim International GmbH	Use of tiotropium salts in the treatment of severe persistant asthma
BRPI0614410A2 (en)	2005-08-15	2011-03-29	Boehringer Ingelheim Int	betamimetic preparation process
US20070086957A1 (en) *	2005-10-10	2007-04-19	Thierry Bouyssou	Combination of medicaments for the treatment of respiratory diseases
US7423146B2 (en)	2005-11-09	2008-09-09	Boehringer Ingelheim International Gmbh	Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
DE102005059602A1 (en)	2005-12-14	2007-06-21	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Micronization process
MX2007009987A (en) *	2005-12-19	2007-10-02	Sicor Inc	Pure and stable tiotropium bromide.
US8163913B2 (en)	2005-12-19	2012-04-24	Sicor Inc.	Forms of tiotropium bromide and processes for preparation thereof
DK1971332T3 (en) *	2006-01-04	2011-04-18	Boehringer Ingelheim Int	Use of tiotropium salts to treat moderate persistent asthma
RS51163B (en)	2006-04-19	2010-10-31	Boehringer Ingelheim International Gmbh.	DIHIDROTIENOPYRIMIDINE FOR THE TREATMENT OF INFLAMMATORY DISEASES
EP1847543A1 (en)	2006-04-19	2007-10-24	Boehringer Ingelheim Pharma GmbH & Co. KG	Dihydrothienopyrimidines for the treatment of inflammatory diseases
US20080051582A1 (en)	2006-07-10	2008-02-28	Sicor Inc.	Process for the preparation of tiotropium bromide
CA2660186A1 (en)	2006-08-07	2008-02-14	Boehringer Ingelheim International Gmbh	Pharmaceutical combinations for the treatment of respiratory diseases
UY30550A1 (en)	2006-08-22	2008-03-31	Boehringer Ingelheim Int	NEW BETA-AGANISTAS ENANTIOMÉRICAMENTE PUROS, PROCEDURES FOR ITS PREPARATION AND ITS USE AS MEDICATIONS
EP1923393A1 (en) *	2006-11-17	2008-05-21	Boehringer Ingelheim Pharma GmbH & Co. KG	Crystalline form of tiotropium bromide and urea
EP1925295A1 (en) *	2006-11-22	2008-05-28	Boehringer Ingelheim Pharma GmbH & Co. KG	Stable powder formulation containing a new antichinolinergic agent
GB0716026D0 (en) *	2007-08-16	2007-09-26	Norton Healthcare Ltd	An inhalable medicament
MX2010004026A (en)	2007-10-19	2010-04-30	Boehringer Ingelheim Int	Substituted piperidino-dihydrothienopyrimidines.
EP2093219A1 (en)	2008-02-22	2009-08-26	Boehringer Ingelheim International Gmbh	Crystalline enantiomer free salt form of a betamimetic and its use as medicine
US20100272811A1 (en) *	2008-07-23	2010-10-28	Alkermes,Inc.	Complex of trospium and pharmaceutical compositions thereof
CN102256963B (en)	2008-12-19	2014-06-11	贝林格尔.英格海姆国际有限公司	Cyclic pyrimidine-4-carboxamides as CCR2 receptor antagonists for the treatment of inflammation, asthma and COPD
EP2201934A1 (en)	2008-12-23	2010-06-30	CHIESI FARMACEUTICI S.p.A.	Tiotropium aerosol formulation products with improved chemical stability
WO2010101538A2 (en)	2009-03-06	2010-09-10	Bilgic Mahmut	New crystal forms
WO2011015883A1 (en)	2009-08-07	2011-02-10	Generics [Uk] Limited	Dichloromethane solvate of tiotropium bromide and its use
NZ597920A (en)	2009-08-07	2014-05-30	Generics Uk Ltd	Anhydrate of tiotropium bromide
EP2513086B1 (en)	2009-12-17	2015-04-29	Boehringer Ingelheim International GmbH	Novel antagonists for ccr2 and uses thereof
ES2674275T3 (en)	2009-12-17	2018-06-28	Centrexion Therapeutics Corporation	CCR2 receptor antagonists and uses thereof
PH12012501535A1 (en)	2010-01-29	2012-10-22	Boehringer Ingelheim Int	Substituted naphthyridines and their use as syk kinase inhibitors
WO2011141474A1 (en)	2010-05-12	2011-11-17	Boehringer Ingelheim International Gmbh	Novel ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments
JP5646736B2 (en)	2010-05-12	2014-12-24	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Novel CCR2 receptor antagonists, methods for their preparation, and their use as drugs
WO2011144501A1 (en)	2010-05-17	2011-11-24	Boehringer Ingelheim International Gmbh	Ccr2 antagonists and uses thereof
WO2011147772A1 (en)	2010-05-25	2011-12-01	Boehringer Ingelheim International Gmbh	Ccr2 receptor antagonists
US8962656B2 (en)	2010-06-01	2015-02-24	Boehringer Ingelheim International Gmbh	CCR2 antagonists
JP5959537B2 (en)	2011-01-28	2016-08-02	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Substituted pyridinyl-pyrimidines and their use as pharmaceuticals
TR201102068A2 (en) *	2011-03-03	2012-09-21	Bi̇lgi̇ç Mahmut	Crystalline substances containing tiotropium bromide
WO2012171863A1 (en)	2011-06-16	2012-12-20	Boehringer Ingelheim International Gmbh	New selective ccr2 antagonists
EP2731941B1 (en)	2011-07-15	2019-05-08	Boehringer Ingelheim International GmbH	Novel and selective ccr2 antagonists
KR101986484B1 (en)	2011-07-26	2019-06-10	베링거 인겔하임 인터내셔날 게엠베하	Substituted quinolines and their use as medicaments
US20130059866A1 (en)	2011-08-24	2013-03-07	Boehringer Ingelheim International Gmbh	Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
CZ304368B6 (en) *	2011-11-28	2014-04-02	Zentiva, K.S.	Tiotropium bromide mixed solvate and process for preparing thereof
GB201200525D0 (en)	2011-12-19	2012-02-29	Teva Branded Pharmaceutical Prod R & D Inc	An inhalable medicament
US9096579B2 (en)	2012-04-20	2015-08-04	Boehringer Ingelheim International Gmbh	Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments
PT2914593T (en)	2012-11-05	2017-04-03	Zentiva Ks	Stabilization of tiotropium solvates
EP2913332A1 (en) *	2014-02-27	2015-09-02	Euticals S.P.A.	Crystalline form of tiotropium bromide with lactose
AU2015233654B2 (en)	2014-03-19	2018-12-06	Boehringer Ingelheim International Gmbh	Heteroaryl Syk inhibitors
US10034866B2 (en)	2014-06-19	2018-07-31	Teva Branded Pharmaceutical Products R&D, Inc.	Inhalable medicament comprising tiotropium
RU2567539C1 (en) *	2015-02-04	2015-11-10	Индивидуальный предприниматель Михайлов Олег Ростиславович	CRYSTALLINE γ-MODIFICATION (1α,2β,4β,5α,7β)-7-[(HYDROXYDI-2-THIENYLACETYL)OXY]-9,9-DIMETHYL-3-OXA-9-AZONIATRICYCLO[3,3,1,02,4]NONANE BROMIDE MONOHYDRATE, METHOD OF THEREOF OBTAINING AND THEREOF-BASED PHARMACEUTICAL COMPOSITION
WO2017138896A1 (en)	2016-02-11	2017-08-17	Sima Patent Ve Lisanslama Hizmetleri Ltd. Şti	Crystalline form of tiotropium bromide anhydrate
WO2018084817A2 (en) *	2016-11-04	2018-05-11	Si̇ma Patent Ve Li̇sanslama Hi̇zmetleri̇ Ltd. Şti̇	A new form of active agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3931041C2 (en) *	1989-09-16	2000-04-06	Boehringer Ingelheim Kg	Esters of thienyl carboxylic acids with amino alcohols, their quaternization products, processes for their preparation and medicaments containing them
ATE177941T1 (en) *	1992-12-09	1999-04-15	Boehringer Ingelheim Pharma	STABILIZED MEDICAL AEROSOL SOLUTIONS
DE19834506A1 (en) *	1998-07-31	2000-02-03	Hexal Ag	Transmucosal therapeutic system for the use of sildenafil
JP4672143B2 (en) *	1998-08-04	2011-04-20	ヤゴテックアーゲー	Pharmaceutical aerosol formulation

2001
- 2001-09-28 WO PCT/EP2001/011225 patent/WO2002030928A1/en not_active Ceased
- 2001-09-28 PL PL366041A patent/PL207870B1/en unknown
- 2001-09-28 AT AT01983510T patent/ATE276253T1/en active
- 2001-09-28 SK SK436-2003A patent/SK287009B6/en not_active IP Right Cessation
- 2001-09-28 KR KR1020037005083A patent/KR100823860B1/en not_active Expired - Lifetime
- 2001-09-28 CN CNB018171435A patent/CN1221549C/en not_active Ceased
- 2001-09-28 HU HU0301022A patent/HU226830B1/en unknown
- 2001-09-28 DE DE50103666T patent/DE50103666D1/en not_active Expired - Lifetime
- 2001-09-28 EE EEP200300171A patent/EE04567B1/en unknown
- 2001-09-28 ME MEP-2008-400A patent/ME00243B/en unknown
- 2001-09-28 EA EA200300457A patent/EA004381B1/en not_active IP Right Cessation
- 2001-09-28 EP EP01983510A patent/EP1326862B1/en not_active Expired - Lifetime
- 2001-09-28 DZ DZ013478A patent/DZ3478A1/en active
- 2001-09-28 CA CA002425539A patent/CA2425539C/en not_active Expired - Lifetime
- 2001-09-28 EP EP04016877A patent/EP1468998A1/en not_active Withdrawn
- 2001-09-28 TR TR2004/02579T patent/TR200402579T4/en unknown
- 2001-09-28 UA UA2003054185A patent/UA74215C2/en unknown
- 2001-09-28 SI SI200130219T patent/SI1326862T1/en unknown
- 2001-09-28 AP APAP/P/2003/002775A patent/AP1572A/en active
- 2001-09-28 DK DK01983510T patent/DK1326862T3/en active
- 2001-09-28 GE GE5214A patent/GEP20063905B/en unknown
- 2001-09-28 JP JP2002534314A patent/JP3764422B2/en not_active Expired - Lifetime
- 2001-09-28 HR HR20030276A patent/HRP20030276B1/en not_active IP Right Cessation
- 2001-09-28 ME MEP-400/08A patent/MEP40008A/en unknown
- 2001-09-28 RS YU27303A patent/RS50218B/en unknown
- 2001-09-28 IL IL15533501A patent/IL155335A0/en active IP Right Grant
- 2001-09-28 AU AU1499602A patent/AU1499602A/en active Pending
- 2001-09-28 CZ CZ20031025A patent/CZ301841B6/en not_active IP Right Cessation
- 2001-09-28 BR BR0114584-3A patent/BR0114584A/en not_active Application Discontinuation
- 2001-09-28 CN CNB2005100977370A patent/CN100519558C/en not_active Ceased
- 2001-09-28 PT PT01983510T patent/PT1326862E/en unknown
- 2001-09-28 NZ NZ525733A patent/NZ525733A/en not_active IP Right Cessation
- 2001-09-28 AU AU2002214996A patent/AU2002214996B2/en not_active Expired
- 2001-09-28 OA OA1200300107A patent/OA12403A/en unknown
- 2001-09-28 MX MXPA03003221A patent/MXPA03003221A/en active IP Right Grant
- 2001-09-28 ES ES01983510T patent/ES2228965T3/en not_active Expired - Lifetime
- 2001-10-02 SA SA01220412A patent/SA01220412B1/en unknown
- 2001-10-09 TW TW090124963A patent/TW589313B/en active
- 2001-10-09 EG EG20011058A patent/EG24142A/en active
- 2001-10-10 PE PE2001001000A patent/PE20020422A1/en active IP Right Grant
- 2001-10-10 UY UY26962A patent/UY26962A1/en not_active Application Discontinuation
- 2001-10-10 MY MYPI20014705A patent/MY126931A/en unknown
- 2001-10-12 AR ARP010104782A patent/AR034389A1/en active IP Right Grant
2003
- 2003-03-26 CR CR6938A patent/CR6938A/en unknown
- 2003-03-28 BG BG107687A patent/BG66161B1/en unknown
- 2003-03-31 ZA ZA200302500A patent/ZA200302500B/en unknown
- 2003-04-07 EC EC2003004540A patent/ECSP034540A/en unknown
- 2003-04-08 MA MA27102A patent/MA25842A1/en unknown
- 2003-04-09 IS IS6772A patent/IS2339B/en unknown
- 2003-04-10 IL IL155335A patent/IL155335A/en unknown
- 2003-04-11 NO NO20031694A patent/NO328465B1/en not_active IP Right Cessation
2008
- 2008-09-19 AR ARP080104109A patent/AR068527A2/en unknown
2013
- 2013-07-11 UY UY34901A patent/UY34901A/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20031694L (en)	2003-04-11
IS2339B (en)	2008-02-15
RS50218B (en)	2009-07-15
CA2425539A1 (en)	2003-04-11
KR20030042008A (en)	2003-05-27
TW589313B (en)	2004-06-01
EG24142A (en)	2008-08-06
EP1326862B1 (en)	2004-09-15
KR100823860B1 (en)	2008-04-21
JP2004526668A (en)	2004-09-02
YU27303A (en)	2006-05-25
AU2002214996B2 (en)	2007-03-15
HUP0301022A3 (en)	2005-12-28
AU1499602A (en)	2002-04-22
PL366041A1 (en)	2005-01-24
NZ525733A (en)	2005-01-28
MA25842A1 (en)	2003-07-01
ATE276253T1 (en)	2004-10-15
NO328465B1 (en)	2010-02-22
IS6772A (en)	2003-04-09
AR068527A2 (en)	2009-11-18
UY34901A (en)	2015-02-27
NO20031694D0 (en)	2003-04-11
CZ301841B6 (en)	2010-07-07
CN1733761A (en)	2006-02-15
BR0114584A (en)	2003-08-26
IL155335A0 (en)	2003-11-23
HUP0301022A2 (en)	2003-10-28
CN100519558C (en)	2009-07-29
DK1326862T3 (en)	2004-11-22
BG107687A (en)	2003-09-30
AP2003002775A0 (en)	2003-03-31
MXPA03003221A (en)	2004-12-03
TR200402579T4 (en)	2004-12-21
ES2228965T3 (en)	2005-04-16
SA01220412B1 (en)	2006-11-05
MY126931A (en)	2006-10-31
CN1221549C (en)	2005-10-05
EE200300171A (en)	2003-06-16
GEP20063905B (en)	2006-08-25
SK287009B6 (en)	2009-09-07
BG66161B1 (en)	2011-09-30
EP1326862A1 (en)	2003-07-16
WO2002030928A1 (en)	2002-04-18
ZA200302500B (en)	2004-04-22
HU226830B1 (en)	2009-11-30
EP1468998A1 (en)	2004-10-20
AP1572A (en)	2006-02-13
EA200300457A1 (en)	2003-10-30
HK1060567A1 (en)	2004-08-13
CA2425539C (en)	2007-04-03
UA74215C2 (en)	2005-11-15
JP3764422B2 (en)	2006-04-05
HRP20030276B1 (en)	2006-02-28
DZ3478A1 (en)	2002-04-18
PE20020422A1 (en)	2002-06-28
HRP20030276A2 (en)	2005-02-28
PT1326862E (en)	2004-11-30
MEP40008A (en)	2011-02-10
HK1086557A1 (en)	2006-09-22
OA12403A (en)	2006-04-18
EA004381B1 (en)	2004-04-29
ECSP034540A (en)	2003-07-25
DE50103666D1 (en)	2004-10-21
SK4362003A3 (en)	2003-08-05
CN1469877A (en)	2004-01-21
IL155335A (en)	2009-02-11
AR034389A1 (en)	2004-02-25
CR6938A (en)	2004-10-28
SI1326862T1 (en)	2005-02-28
ME00243B (en)	2011-05-10
PL207870B1 (en)	2011-02-28
UY26962A1 (en)	2002-06-20

Legal Events

Date	Code	Title	Description
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231

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