MY126931A - Crystalline monohydrate of tiotropiumbromide, method for producing the same and the use thereof in the production of a medicament - Google Patents

Crystalline monohydrate of tiotropiumbromide, method for producing the same and the use thereof in the production of a medicament

Info

Publication number
MY126931A
MY126931A MYPI20014705A MYPI20014705A MY126931A MY 126931 A MY126931 A MY 126931A MY PI20014705 A MYPI20014705 A MY PI20014705A MY PI20014705 A MYPI20014705 A MY PI20014705A MY 126931 A MY126931 A MY 126931A
Authority
MY
Malaysia
Prior art keywords
tiotropiumbromide
medicament
producing
production
same
Prior art date
Application number
MYPI20014705A
Inventor
Rolf Banholzer Dr
Peter Sieger Dr
Christian Kulinna Dr
Michael Trunk Dr
Manfred Graulich Dr
Peter Specht Dr
Meissner Helmut
Mathes Andreas
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY126931(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MY126931A publication Critical patent/MY126931A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

THE INVENTION RELATES TO A CRYSTALLINE MONOHYDRATE OF (1?, 2?, 4?, 5ALPHA, 7?) - 7 - (HYDROXYDI-2-2THEINYLACETY) OXY]-9, 9-DIMETHY-3-OXA-9-AZONIATRICYCLO [3.3.1.0 ?, ?] NONANE-BROMIDE, PROCESSESS FOR THE PREPARATION THEREOF, AS WELL AS THE USE THEREOF FOR PREPARING A PHARMACEUTICAL COMPOSITION, PARTICULARLY FOR PREPARING A PHARMACEUTICAL COMPOSITION HAVING AN ANTICHOLINERGIC ACTIVITY.
MYPI20014705A 2000-10-12 2001-10-10 Crystalline monohydrate of tiotropiumbromide, method for producing the same and the use thereof in the production of a medicament MY126931A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10050621 2000-10-12

Publications (1)

Publication Number Publication Date
MY126931A true MY126931A (en) 2006-10-31

Family

ID=7659568

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20014705A MY126931A (en) 2000-10-12 2001-10-10 Crystalline monohydrate of tiotropiumbromide, method for producing the same and the use thereof in the production of a medicament

Country Status (46)

Country Link
EP (2) EP1326862B1 (en)
JP (1) JP3764422B2 (en)
KR (1) KR100823860B1 (en)
CN (2) CN100519558C (en)
AP (1) AP1572A (en)
AR (2) AR034389A1 (en)
AT (1) ATE276253T1 (en)
AU (2) AU1499602A (en)
BG (1) BG66161B1 (en)
BR (1) BR0114584A (en)
CA (1) CA2425539C (en)
CR (1) CR6938A (en)
CZ (1) CZ301841B6 (en)
DE (1) DE50103666D1 (en)
DK (1) DK1326862T3 (en)
DZ (1) DZ3478A1 (en)
EA (1) EA004381B1 (en)
EC (1) ECSP034540A (en)
EE (1) EE04567B1 (en)
EG (1) EG24142A (en)
ES (1) ES2228965T3 (en)
GE (1) GEP20063905B (en)
HR (1) HRP20030276B1 (en)
HU (1) HU226830B1 (en)
IL (2) IL155335A0 (en)
IS (1) IS2339B (en)
MA (1) MA25842A1 (en)
ME (2) MEP40008A (en)
MX (1) MXPA03003221A (en)
MY (1) MY126931A (en)
NO (1) NO328465B1 (en)
NZ (1) NZ525733A (en)
OA (1) OA12403A (en)
PE (1) PE20020422A1 (en)
PL (1) PL207870B1 (en)
PT (1) PT1326862E (en)
RS (1) RS50218B (en)
SA (1) SA01220412B1 (en)
SI (1) SI1326862T1 (en)
SK (1) SK287009B6 (en)
TR (1) TR200402579T4 (en)
TW (1) TW589313B (en)
UA (1) UA74215C2 (en)
UY (2) UY26962A1 (en)
WO (1) WO2002030928A1 (en)
ZA (1) ZA200302500B (en)

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GEP20063905B (en) 2006-08-25
KR20030042008A (en) 2003-05-27
AR034389A1 (en) 2004-02-25
NZ525733A (en) 2005-01-28
IL155335A0 (en) 2003-11-23
PL207870B1 (en) 2011-02-28
IS6772A (en) 2003-04-09
EA004381B1 (en) 2004-04-29
SK4362003A3 (en) 2003-08-05
PL366041A1 (en) 2005-01-24
NO328465B1 (en) 2010-02-22
HU226830B1 (en) 2009-11-30
WO2002030928A1 (en) 2002-04-18
HUP0301022A2 (en) 2003-10-28
ATE276253T1 (en) 2004-10-15
JP3764422B2 (en) 2006-04-05
TR200402579T4 (en) 2004-12-21
CZ301841B6 (en) 2010-07-07
NO20031694L (en) 2003-04-11
AU2002214996B2 (en) 2007-03-15
BG107687A (en) 2003-09-30
JP2004526668A (en) 2004-09-02
PE20020422A1 (en) 2002-06-28
IL155335A (en) 2009-02-11
NO20031694D0 (en) 2003-04-11
MEP40008A (en) 2011-02-10
CA2425539C (en) 2007-04-03
BG66161B1 (en) 2011-09-30
CN1469877A (en) 2004-01-21
HUP0301022A3 (en) 2005-12-28
MXPA03003221A (en) 2004-12-03
AU1499602A (en) 2002-04-22
MA25842A1 (en) 2003-07-01
ME00243B (en) 2011-05-10
CN1221549C (en) 2005-10-05
EE200300171A (en) 2003-06-16
DE50103666D1 (en) 2004-10-21
AR068527A2 (en) 2009-11-18
TW589313B (en) 2004-06-01
EP1326862A1 (en) 2003-07-16
CR6938A (en) 2004-10-28
UY34901A (en) 2015-02-27
BR0114584A (en) 2003-08-26
RS50218B (en) 2009-07-15
EG24142A (en) 2008-08-06
CN100519558C (en) 2009-07-29
ZA200302500B (en) 2004-04-22
SI1326862T1 (en) 2005-02-28
HRP20030276A2 (en) 2005-02-28
ES2228965T3 (en) 2005-04-16
DK1326862T3 (en) 2004-11-22
EE04567B1 (en) 2005-12-15
IS2339B (en) 2008-02-15
HK1060567A1 (en) 2004-08-13
CN1733761A (en) 2006-02-15
YU27303A (en) 2006-05-25
KR100823860B1 (en) 2008-04-21
UA74215C2 (en) 2005-11-15
EP1326862B1 (en) 2004-09-15
UY26962A1 (en) 2002-06-20
SK287009B6 (en) 2009-09-07
SA01220412B1 (en) 2006-11-05
OA12403A (en) 2006-04-18
EP1468998A1 (en) 2004-10-20
AP2003002775A0 (en) 2003-03-31
AP1572A (en) 2006-02-13
HRP20030276B1 (en) 2006-02-28
PT1326862E (en) 2004-11-30
DZ3478A1 (en) 2002-04-18
CA2425539A1 (en) 2003-04-11
ECSP034540A (en) 2003-07-25
HK1086557A1 (en) 2006-09-22
EA200300457A1 (en) 2003-10-30

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