EE04676B1 - Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine - Google Patents

Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine

Info

Publication number
EE04676B1
EE04676B1 EEP200000626A EEP200000626A EE04676B1 EE 04676 B1 EE04676 B1 EE 04676B1 EE P200000626 A EEP200000626 A EE P200000626A EE P200000626 A EEP200000626 A EE P200000626A EE 04676 B1 EE04676 B1 EE 04676B1
Authority
EE
Estonia
Prior art keywords
imidazopidine
derivatives
preparation
gastric acid
acid secretion
Prior art date
Application number
EEP200000626A
Other languages
English (en)
Estonian (et)
Inventor
Amin Kosrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000626A publication Critical patent/EE200000626A/xx
Publication of EE04676B1 publication Critical patent/EE04676B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200000626A 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine EE04676B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000662 WO1999055705A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
EE200000626A EE200000626A (et) 2002-04-15
EE04676B1 true EE04676B1 (et) 2006-08-15

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200000626A EE04676B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Country Status (33)

Country Link
US (2) US6313137B1 (de)
EP (4) EP1491542B1 (de)
JP (2) JP3883383B2 (de)
KR (3) KR100650472B1 (de)
CN (2) CN1174980C (de)
AR (2) AR015768A1 (de)
AT (4) ATE372340T1 (de)
AU (2) AU769190B2 (de)
BR (2) BR9909996B1 (de)
CA (2) CA2329922C (de)
CZ (2) CZ293977B6 (de)
DE (4) DE69937077T2 (de)
DK (2) DK1073657T3 (de)
EE (2) EE04676B1 (de)
ES (2) ES2249913T3 (de)
HU (2) HUP0102313A3 (de)
ID (2) ID26819A (de)
IL (4) IL139200A0 (de)
IS (2) IS5684A (de)
MY (2) MY121379A (de)
NO (2) NO318203B1 (de)
NZ (2) NZ507638A (de)
PL (2) PL195000B1 (de)
RU (2) RU2235725C2 (de)
SA (2) SA99200065B1 (de)
SE (1) SE9801526D0 (de)
SI (1) SI1073656T1 (de)
SK (2) SK14912000A3 (de)
TR (4) TR200003176T2 (de)
TW (2) TW490466B (de)
UA (2) UA66846C2 (de)
WO (2) WO1999055705A1 (de)
ZA (2) ZA200005796B (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
ES2261643T3 (es) * 2001-02-13 2006-11-16 Astrazeneca Ab Nueva formulacion de liberacion modificada.
EE05234B1 (et) * 2001-03-08 2009-12-15 Astrazeneca Ab 6-karboksamidoimidaso[1,2-a] pridiinihendite kasutamine ravimi p?hjustatud maohaavandi v„ltimiseks
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
ATE378336T1 (de) 2002-09-19 2007-11-15 Schering Corp Imidazopyridine als hemmstoffe cyclin abhängiger kinasen
RS20050377A (sr) 2002-11-19 2007-11-15 Altana Pharma Ag., 8-supstituisani imidazopiridini
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
GEP20084341B (en) * 2003-02-26 2008-03-25 Sugen Inc Aminoheteroaryl compounds as protein kinase inhibitors
SI1606261T1 (sl) 2003-03-10 2010-03-31 Nycomed Gmbh Novi postopek za pripravo roflumilasta
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP1974730A1 (de) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridin-Derivate zur Behandlung von Schlafstörungen durch stummen gastroösophagealen Reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
WO2005070927A2 (en) * 2004-01-26 2005-08-04 Altana Pharma Ag 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AU2005315303A1 (en) * 2004-12-17 2006-06-22 Pfizer Inc. Chromane derivatives useful as acid pump antagonists
US8663694B2 (en) 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
MY147647A (en) * 2005-03-21 2012-12-31 S Bio Pte Ltd Imidazo [1,2-a] pyridine derivatives : preparation and pharmaceutical applications
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
EP1861095A1 (de) * 2005-03-24 2007-12-05 Glaxo Group Limited Derivate von imidazo(1,2-a)pyridin als nützliche medikamente zur behandlung von magen-darm-erkrankungen
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
DK1959955T3 (da) * 2005-12-05 2011-02-07 Pfizer Prod Inc Fremgangsmåde til behandling af abnorm cellevækst
RU2387650C2 (ru) * 2005-12-05 2010-04-27 Пфайзер Продактс Инк. Полиморфы с-met/hgfr ингибитора
EP1996589A1 (de) * 2006-03-17 2008-12-03 RaQualia Pharma Inc Chromanderivate
US8728527B2 (en) 2006-07-24 2014-05-20 Luminus Biosciences, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
WO2009122435A2 (en) * 2008-03-31 2009-10-08 Council Of Scientific & Industrial Research A simultaneous method for the preparation of a mixture of 3- acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3- acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
RU2403904C1 (ru) * 2009-02-26 2010-11-20 Федеральное государственное учреждение "Научно-исследовательский институт по изучению лепры Федерального агентства по здравоохранению и социальному развитию Росздрава" Способ профилактики острых гастродуоденальных язв у больных колоректальным раком в раннем послеоперационном периоде
MX2012000275A (es) 2009-07-09 2012-02-08 Raqualia Pharma Inc Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal.
RU2673542C2 (ru) * 2013-06-25 2018-11-28 Ф. Хоффманн-Ля Рош Аг Соединения для лечения спинальной мышечной атрофии
JP6616772B2 (ja) 2013-12-16 2019-12-04 アサナ・バイオサイエンシズ，リミテッド・ライアビリティ・カンパニー Ｐ２ｘ３および／またはｐ２ｘ２／３化合物ならびに方法
DK3122748T3 (en) * 2014-03-24 2018-11-05 Arqule Inc METHOD OF PREPARING 3- (3- (4- (1-AMINOCYCLOBUTYL) PHENYL) -5-PHENYL-3H-IMIDAZO [4,5-B] PYRIDIN-2-YL) PYRIDIN-2-AMINE
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂
MX2020010636A (es) 2018-04-10 2020-10-28 Bayer Ag Proceso para la produccion de acidos 2,6-dialquilfenilaceticos.
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
CN114901262A (zh) 2019-11-04 2022-08-12 辛克鲁斯制药控股有限公司 X842的口服制剂
IL312564A (en) 2021-11-05 2024-07-01 Cinclus Pharma Holding Ab Publ Polymorphs of the hydrochloride salt of linfarezan glurate
CN118414334A (zh) 2021-11-05 2024-07-30 辛克鲁斯制药控股有限公司 （Publ） 谷氨酸利那拉生甲磺酸盐的多晶型物
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
JP2026503096A (ja) 2023-01-11 2026-01-27 シンクルス・ファーマ・ホールディング・アクチエボラグ・パブリーク リナプラザングルレート（ｌｉｎａｐｒａｚａｎ ｇｌｕｒａｔｅ）のマレイン酸塩の多形
EP4649079A1 (de) 2023-01-11 2025-11-19 Cinclus Pharma Holding AB (publ) Polymorphe des hydrobromidsalzes von linaprazanglurat
PE20260034A1 (es) * 2023-02-01 2026-01-09 Jeil Pharmaceutical Co Ltd Formulacion farmaceutica, metodo de preparacion para la misma y composicion de tableta
WO2025215593A1 (en) * 2024-04-12 2025-10-16 Hetero Labs Limited An improved process for preparation of zastaprazan
KR20260002254A (ko) * 2024-06-28 2026-01-06 온코닉테라퓨틱스 주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염의 결정형 및 이의 제조방법
WO2026005545A1 (ko) * 2024-06-28 2026-01-02 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염 및 이의 제조방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (de) 1981-06-26 1986-03-05 Schering Corporation Imidazo(1,2-a)pyridine und -pyrazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (de) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridinverbindungen und Verfahren zu ihrer Herstellung
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound
GB9102997D0 (en) * 1991-02-13 1991-03-27 Pfizer Ltd Therapeutic agents
GB9107513D0 (en) * 1991-04-10 1991-05-29 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof

Also Published As

Publication number Publication date
CN1174980C (zh) 2004-11-10
NO20005450L (no) 2000-12-22
NO317262B1 (no) 2004-09-27
HUP0102425A2 (hu) 2001-11-28
RU2235725C2 (ru) 2004-09-10
SK285768B6 (sk) 2007-07-06
RU2238271C2 (ru) 2004-10-20
HUP0102313A2 (hu) 2001-12-28
ZA200005796B (en) 2002-01-18
KR100595806B1 (ko) 2006-07-03
CZ293977B6 (cs) 2004-09-15
WO1999055706A9 (en) 2000-03-16
EP1491543B1 (de) 2007-09-05
ID27530A (id) 2001-04-12
KR20010043133A (ko) 2001-05-25
HUP0102425A3 (en) 2002-12-28
AR015768A1 (es) 2001-05-16
CN1165535C (zh) 2004-09-08
CA2329922A1 (en) 1999-11-04
NO20005450D0 (no) 2000-10-27
ID26819A (id) 2001-02-15
IL139200A0 (en) 2001-11-25
SA99200064B1 (ar) 2006-10-11
SK14912000A3 (sk) 2001-06-11
CZ20003982A3 (cs) 2001-02-14
IL139297A (en) 2007-06-03
NZ507639A (en) 2004-01-30
CN1307577A (zh) 2001-08-08
BR9909995B1 (pt) 2010-07-13
TR200003176T2 (tr) 2001-03-21
JP2002513024A (ja) 2002-05-08
AU4300699A (en) 1999-11-16
NO20005451D0 (no) 2000-10-27
DK1073656T3 (da) 2006-01-16
KR20010043134A (ko) 2001-05-25
NZ507638A (en) 2003-10-31
TW490466B (en) 2002-06-11
DE69927803D1 (de) 2006-03-02
US6313137B1 (en) 2001-11-06
NO318203B1 (no) 2005-02-14
EP1073656B1 (de) 2005-10-19
SA99200065A (ar) 2005-12-03
JP3883383B2 (ja) 2007-02-21
TWI250159B (en) 2006-03-01
HK1036984A1 (en) 2002-01-25
DE69928792D1 (de) 2006-01-12
DE69937076D1 (de) 2007-10-18
CZ292567B6 (cs) 2003-10-15
TR200102728T2 (tr) 2002-06-21
ES2249913T3 (es) 2006-04-01
CZ20003981A3 (cs) 2001-03-14
BR9909996B1 (pt) 2010-08-24
ATE312101T1 (de) 2005-12-15
BR9909996A (pt) 2000-12-26
IS5683A (is) 2000-10-25
PL343801A1 (en) 2001-09-10
EP1491543A1 (de) 2004-12-29
DE69927803T2 (de) 2006-07-06
NO20005451L (no) 2000-12-27
PL343797A1 (en) 2001-09-10
SA99200065B1 (ar) 2006-11-07
ZA200005797B (en) 2002-01-18
US6313136B1 (en) 2001-11-06
CA2329921A1 (en) 1999-11-04
MY121379A (en) 2006-01-28
CA2329922C (en) 2006-04-11
ES2252975T3 (es) 2006-05-16
KR100650472B1 (ko) 2006-11-28
EP1073656A1 (de) 2001-02-07
KR100595805B1 (ko) 2006-07-03
EP1491542A2 (de) 2004-12-29
HUP0102313A3 (en) 2002-10-28
IS5684A (is) 2000-10-25
EE04916B1 (et) 2007-10-15
EP1491542A3 (de) 2005-01-05
DK1073657T3 (da) 2006-03-13
SE9801526D0 (sv) 1998-04-29
KR20050121760A (ko) 2005-12-27
IL139200A (en) 2010-04-29
AU4300799A (en) 1999-11-16
DE69937077D1 (de) 2007-10-18
BR9909995A (pt) 2000-12-26
HK1033457A1 (en) 2001-08-31
PL195000B1 (pl) 2007-07-31
DE69937077T2 (de) 2008-05-29
EE200000664A (et) 2002-04-15
EP1491542B1 (de) 2007-09-05
HK1036981A1 (en) 2002-01-25
EP1073657B1 (de) 2005-12-07
CN1306533A (zh) 2001-08-01
TR200003149T2 (tr) 2001-03-21
ATE372339T1 (de) 2007-09-15
WO1999055705A1 (en) 1999-11-04
HK1071139A1 (en) 2005-07-08
ATE307130T1 (de) 2005-11-15
EE200000626A (et) 2002-04-15
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
MY121389A (en) 2006-01-28
AU769108B2 (en) 2004-01-15
JP2002513025A (ja) 2002-05-08
DE69937076T2 (de) 2008-05-29
DE69928792T2 (de) 2006-07-20
IL139297A0 (en) 2001-11-25
SK14922000A3 (sk) 2001-06-11
TR200102612T2 (tr) 2002-06-21
UA66846C2 (uk) 2004-06-15
JP3692034B2 (ja) 2005-09-07
AR015769A1 (es) 2001-05-16
HK1033317A1 (en) 2001-08-24
ATE372340T1 (de) 2007-09-15
EP1073657A1 (de) 2001-02-07
AU769190B2 (en) 2004-01-22
UA67769C2 (uk) 2004-07-15

Similar Documents

Publication Publication Date Title
EE04676B1 (et) Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine
EE04060B1 (et) Heterotsüklilised ühendid maohappesekretsiooni inhibeerimiseks, protsess nende valmistamiseks ja ravimkoostised
EE200100437A (et) C-21 modifitseeritud epotioloonid, nende valmistamise meetod ning kasutamine
EE200200704A (et) Uued ühendid, meetod nende valmistamiseks ning nende kasutamine
EE200200470A (et) Uued ühendid, meetod nende valmistamiseks ning nende kasutamine
ZA200109073B (en) Compositions for treatment of disorders of the oesophagus.
EE05223B1 (et) Triasoloprimidiini hendid, meetod nende valmistamiseks ning nende kasutamine
EE200100574A (et) Uued ühendid, nende valmistamise meetod ning kasutamine
IT1317741B1 (it) Metodo per la preparazione di 5-cianoftalide.
HUP0300592A3 (en) Process for the preparation of 2-halobenzoic acid derivatives
NO20004722D0 (no) Faste, hurtigdesintegrerende cetirizin-formuleringer
NO20006039L (no) Fremgangsmåte for fremstilling av 4-karboksyamino-2- substituert-1,2,3,4- tetrahydroquinolin
EE04739B1 (et) Tienüülasolüülalkoksüetaanamiinderivaadid, nende ja nende soolade valmistamismeetod ja kasutamine, farmatseutiline kompositsioon ning vaheühend ja selle valmistamismeetod
EE03682B1 (et) Asendatud bensimidasooli derivaadid, protsessid nende valmistamiseks ning nende kasutamine
EE200100383A (et) L-fenüülefriinvesinikkloriidi valmistamise meetod
IL141165A0 (en) New imidazopyridine compounds for the inhibition of acid secretion, pharmaceutical compositions thereof and process for preparing the same
FR2833259B1 (fr) Procede de preparation de 2-arylbenzofuranes, composes intermediaires, 2-arylbenzofuranes et compositions les comprenant
ZA995597B (en) Process for the preparation of nicotinic acid.
EE200200697A (et) Uued ühendid, meetod nende valmistamiseks ning nende kasutamine
IL157709A0 (en) Process for the preparation of 1,2-benzisoxazole-3-acetic acid
EE200100573A (et) Uued ühendid, nende valmistamise meetod ning kasutamine
ZA200006045B (en) Gastric acid secretion.
FI972742L (fi) Liuotinvapaa menetelmä 2,6-difluoribentseenin valmistamiseksi
EE200000752A (et) Alfa-D-ksüloosiühendid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon
HUP0102447A3 (en) Novel octahydro-6,10-dioxo-6h-pyridazino/1,2a//1,2/diazepin-1-carboxylic acid derivatives, preparation method and use for preparing therapeutically active compounds

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20100423