EE04676B1 - Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine - Google Patents

Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine

Info

Publication number
EE04676B1
EE04676B1 EEP200000626A EEP200000626A EE04676B1 EE 04676 B1 EE04676 B1 EE 04676B1 EE P200000626 A EEP200000626 A EE P200000626A EE P200000626 A EEP200000626 A EE P200000626A EE 04676 B1 EE04676 B1 EE 04676B1
Authority
EE
Estonia
Prior art keywords
imidazopidine
derivatives
preparation
gastric acid
acid secretion
Prior art date
Application number
EEP200000626A
Other languages
English (en)
Estonian (et)
Inventor
Amin Kosrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000626A publication Critical patent/EE200000626A/xx
Publication of EE04676B1 publication Critical patent/EE04676B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200000626A 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine EE04676B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000662 WO1999055705A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
EE200000626A EE200000626A (et) 2002-04-15
EE04676B1 true EE04676B1 (et) 2006-08-15

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200000626A EE04676B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Country Status (33)

Country Link
US (2) US6313137B1 (de)
EP (4) EP1073656B1 (de)
JP (2) JP3883383B2 (de)
KR (3) KR100650472B1 (de)
CN (2) CN1165535C (de)
AR (2) AR015769A1 (de)
AT (4) ATE312101T1 (de)
AU (2) AU769108B2 (de)
BR (2) BR9909996B1 (de)
CA (2) CA2329922C (de)
CZ (2) CZ293977B6 (de)
DE (4) DE69937077T2 (de)
DK (2) DK1073657T3 (de)
EE (2) EE04676B1 (de)
ES (2) ES2249913T3 (de)
HU (2) HUP0102425A3 (de)
ID (2) ID26819A (de)
IL (4) IL139200A0 (de)
IS (2) IS5684A (de)
MY (2) MY121379A (de)
NO (2) NO317262B1 (de)
NZ (2) NZ507638A (de)
PL (2) PL343797A1 (de)
RU (2) RU2235725C2 (de)
SA (2) SA99200064B1 (de)
SE (1) SE9801526D0 (de)
SI (1) SI1073656T1 (de)
SK (2) SK285768B6 (de)
TR (4) TR200003176T2 (de)
TW (2) TW490466B (de)
UA (2) UA67769C2 (de)
WO (2) WO1999055705A1 (de)
ZA (2) ZA200005797B (de)

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US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
CN1491104A (zh) * 2001-02-13 2004-04-21 新型改进释放制剂
JP2004520422A (ja) * 2001-03-08 2004-07-08 アストラゼネカ・アクチエボラーグ 新しい用途
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
DE60317529T2 (de) 2002-09-19 2008-09-25 Schering Corp. Imidazopyridine als hemmstoffe cyclin abhängiger kinasen
KR20050086584A (ko) 2002-11-19 2005-08-30 알타나 파마 아게 8-치환 이미다조피리딘
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
RS53118B (sr) * 2003-02-26 2014-06-30 Sugen Inc. Aminoheteroaril jedinjenja kao inhibitori protein kinaze
DK1606261T3 (da) 2003-03-10 2010-01-18 Nycomed Gmbh Hidtil ukendt fremgangsmåde til fremstilling af roflumilast
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2005041961A1 (en) * 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
US20080033006A1 (en) * 2004-01-26 2008-02-07 Altana Pharma Ag 1,2,4-Triazolo[ 1,5-A] Pyridines as Gastric Acid Secretion Inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
ATE405262T1 (de) * 2004-12-17 2008-09-15 Pfizer Chroman-derivate als säurepumpenantagonisten
AU2006224619B2 (en) 2005-03-16 2012-06-07 Takeda Gmbh Taste masked dosage form containing roflumilast
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
MX2007011710A (es) * 2005-03-21 2007-11-20 S Bio Pte Ltd Derivados de imidazo[1,2-a]piridina, preparacion y aplicaciones farmaceuticas.
PE20061110A1 (es) * 2005-03-24 2006-10-20 Glaxo Group Ltd Derivados de imidazopiridina como antagonistas de la bomba de acido (apa)
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
KR101146852B1 (ko) * 2005-12-05 2012-05-16 화이자 프로덕츠 인크. Ｃ?ｍｅｔ／ｈｇｆｒ 억제제의 다형체
BRPI0619424B1 (pt) * 2005-12-05 2022-02-08 Pfizer Products Inc Uso de inibidores c-met/hgfrs para a fabricação de medicamentos
BRPI0708808A2 (pt) * 2006-03-17 2011-06-14 Raqualia Pharma Inc Derivados de cromano
WO2008013785A2 (en) 2006-07-24 2008-01-31 Singh-Broemer And Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
US8513226B2 (en) * 2008-03-31 2013-08-20 Council Of Scientific And Industrial Research Simultaneous method for the preparation of a mixture of 3-acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3-acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
RU2403904C1 (ru) * 2009-02-26 2010-11-20 Федеральное государственное учреждение "Научно-исследовательский институт по изучению лепры Федерального агентства по здравоохранению и социальному развитию Росздрава" Способ профилактики острых гастродуоденальных язв у больных колоректальным раком в раннем послеоперационном периоде
US8648080B2 (en) * 2009-07-09 2014-02-11 Raqualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
AR096684A1 (es) * 2013-06-25 2016-01-27 Ptc Therapeutics Inc Compuestos para tratar atrofia muscular espinal
WO2015095128A1 (en) 2013-12-16 2015-06-25 Asana Biosciences, Llc P2x3 and/or p2x2/3 compounds and methods
WO2015148464A1 (en) * 2014-03-24 2015-10-01 Arqule Inc. Process of preparing 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3h-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) * 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
EP3749697A4 (de) 2018-02-05 2021-11-03 Bio-Rad Laboratories, Inc. Chromatografieharz mit einem liganden mit anionenaustausch-hydrophobem mischmodus
KR102706151B1 (ko) 2018-04-10 2024-09-13 바이엘 악티엔게젤샤프트 2,6-디알킬페닐아세트산을 제조하는 방법
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
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JP2024530045A (ja) 2021-11-05 2024-08-14 シンクルス・ファーマ・ホールディング・アクチエボラグ リナプラザングルレート塩酸塩の多形
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
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KR20260002254A (ko) * 2024-06-28 2026-01-06 온코닉테라퓨틱스 주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염의 결정형 및 이의 제조방법

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ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (de) * 1981-06-26 1986-03-05 Schering Corporation Imidazo(1,2-a)pyridine und -pyrazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
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GB9107513D0 (en) * 1991-04-10 1991-05-29 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof

Also Published As

Publication number Publication date
EE200000626A (et) 2002-04-15
WO1999055705A1 (en) 1999-11-04
EP1491543A1 (de) 2004-12-29
MY121379A (en) 2006-01-28
KR20050121760A (ko) 2005-12-27
TW490466B (en) 2002-06-11
CZ293977B6 (cs) 2004-09-15
HUP0102425A3 (en) 2002-12-28
DE69937077T2 (de) 2008-05-29
HK1071139A1 (en) 2005-07-08
DE69937076T2 (de) 2008-05-29
DE69937077D1 (de) 2007-10-18
BR9909996A (pt) 2000-12-26
MY121389A (en) 2006-01-28
JP3692034B2 (ja) 2005-09-07
SK285768B6 (sk) 2007-07-06
JP2002513024A (ja) 2002-05-08
SE9801526D0 (sv) 1998-04-29
CA2329922A1 (en) 1999-11-04
HK1036984A1 (en) 2002-01-25
IL139297A (en) 2007-06-03
IL139200A0 (en) 2001-11-25
DK1073656T3 (da) 2006-01-16
IS5683A (is) 2000-10-25
TR200102728T2 (tr) 2002-06-21
EE200000664A (et) 2002-04-15
HUP0102313A3 (en) 2002-10-28
ATE312101T1 (de) 2005-12-15
AR015769A1 (es) 2001-05-16
KR20010043133A (ko) 2001-05-25
NO318203B1 (no) 2005-02-14
DE69927803D1 (de) 2006-03-02
SA99200065B1 (ar) 2006-11-07
HUP0102313A2 (hu) 2001-12-28
RU2238271C2 (ru) 2004-10-20
NO20005450D0 (no) 2000-10-27
RU2235725C2 (ru) 2004-09-10
EP1491543B1 (de) 2007-09-05
AU4300699A (en) 1999-11-16
KR20010043134A (ko) 2001-05-25
DE69928792D1 (de) 2006-01-12
JP2002513025A (ja) 2002-05-08
TR200102612T2 (tr) 2002-06-21
CN1174980C (zh) 2004-11-10
US6313137B1 (en) 2001-11-06
NO317262B1 (no) 2004-09-27
NZ507639A (en) 2004-01-30
AR015768A1 (es) 2001-05-16
CN1306533A (zh) 2001-08-01
UA67769C2 (uk) 2004-07-15
NO20005450L (no) 2000-12-22
ZA200005797B (en) 2002-01-18
NZ507638A (en) 2003-10-31
TR200003149T2 (tr) 2001-03-21
BR9909995A (pt) 2000-12-26
NO20005451L (no) 2000-12-27
HK1033317A1 (en) 2001-08-24
EP1073656B1 (de) 2005-10-19
SK14912000A3 (sk) 2001-06-11
WO1999055706A1 (en) 1999-11-04
ATE307130T1 (de) 2005-11-15
ID26819A (id) 2001-02-15
DK1073657T3 (da) 2006-03-13
IS5684A (is) 2000-10-25
HK1033457A1 (en) 2001-08-31
TR200003176T2 (tr) 2001-03-21
EP1073656A1 (de) 2001-02-07
ES2249913T3 (es) 2006-04-01
DE69927803T2 (de) 2006-07-06
IL139200A (en) 2010-04-29
DE69928792T2 (de) 2006-07-20
ZA200005796B (en) 2002-01-18
KR100650472B1 (ko) 2006-11-28
US6313136B1 (en) 2001-11-06
EP1073657A1 (de) 2001-02-07
EE04916B1 (et) 2007-10-15
AU769190B2 (en) 2004-01-22
SI1073656T1 (sl) 2006-02-28
EP1491542A3 (de) 2005-01-05
ATE372339T1 (de) 2007-09-15
CA2329921A1 (en) 1999-11-04
PL343797A1 (en) 2001-09-10
HUP0102425A2 (hu) 2001-11-28
IL139297A0 (en) 2001-11-25
CN1307577A (zh) 2001-08-08
UA66846C2 (uk) 2004-06-15
SA99200064B1 (ar) 2006-10-11
ES2252975T3 (es) 2006-05-16
EP1491542B1 (de) 2007-09-05
BR9909996B1 (pt) 2010-08-24
KR100595806B1 (ko) 2006-07-03
SA99200065A (ar) 2005-12-03
PL195000B1 (pl) 2007-07-31
CZ292567B6 (cs) 2003-10-15
NO20005451D0 (no) 2000-10-27
ATE372340T1 (de) 2007-09-15
BR9909995B1 (pt) 2010-07-13
CZ20003982A3 (cs) 2001-02-14
TWI250159B (en) 2006-03-01
WO1999055706A9 (en) 2000-03-16
CZ20003981A3 (cs) 2001-03-14
EP1491542A2 (de) 2004-12-29
HK1036981A1 (en) 2002-01-25
DE69937076D1 (de) 2007-10-18
EP1073657B1 (de) 2005-12-07
SK14922000A3 (sk) 2001-06-11
PL343801A1 (en) 2001-09-10
CN1165535C (zh) 2004-09-08
CA2329922C (en) 2006-04-11
AU769108B2 (en) 2004-01-15
JP3883383B2 (ja) 2007-02-21
AU4300799A (en) 1999-11-16
ID27530A (id) 2001-04-12
KR100595805B1 (ko) 2006-07-03

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