EE04917B1 - Antihistamiinsed spirohendid, vahehendid ja farmatseutiline kompositsioon ning nende valmistamismeetodid ja kasutamine - Google Patents

Antihistamiinsed spirohendid, vahehendid ja farmatseutiline kompositsioon ning nende valmistamismeetodid ja kasutamine

Info

Publication number: EE04917B1
Authority: EE; Estonia
Prior art keywords: antihistamine; spirits; intermediates; preparation; methods
Prior art date: 1998-12-19

Application number

EEP200100328A

Other languages

English (en)

Estonian (et)

Inventor

Eduard Janssens Frans

Elisabeth Leenaerts Joseph

Original Assignee

Janssen Pharmaceutica N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-19

Filing date

1999-12-15

Publication date

2007-10-15

1999-12-15 Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.

2002-08-15 Publication of EE200100328A publication Critical patent/EE200100328A/xx

2007-10-15 Publication of EE04917B1 publication Critical patent/EE04917B1/xx

Links

GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
230000001387 anti-histamine Effects 0.000 title 1
239000000739 antihistaminic agent Substances 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
235000015096 spirit Nutrition 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/20—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Immunology (AREA)
Dermatology (AREA)
Ophthalmology & Optometry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Dental Preparations (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

EEP200100328A 1998-12-19 1999-12-15 Antihistamiinsed spirohendid, vahehendid ja farmatseutiline kompositsioon ning nende valmistamismeetodid ja kasutamine EE04917B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98204347		1998-12-19
PCT/EP1999/010176 WO2000037470A1 (fr)	1998-12-19	1999-12-15	Composes spiro antihistaminiques

Publications (2)

Publication Number	Publication Date
EE200100328A EE200100328A (et)	2002-08-15
EE04917B1 true EE04917B1 (et)	2007-10-15

Family

ID=8234498

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200100328A EE04917B1 (et)	1998-12-19	1999-12-15	Antihistamiinsed spirohendid, vahehendid ja farmatseutiline kompositsioon ning nende valmistamismeetodid ja kasutamine

Country Status (37)

Country	Link
US (2)	US7148214B1 (fr)
EP (1)	EP1144411B1 (fr)
JP (1)	JP4601175B2 (fr)
KR (1)	KR100598725B1 (fr)
CN (1)	CN1258533C (fr)
AR (1)	AR021888A1 (fr)
AT (1)	ATE294178T1 (fr)
AU (1)	AU764820C (fr)
BG (1)	BG65133B1 (fr)
BR (1)	BR9916371A (fr)
CA (1)	CA2355939C (fr)
CO (1)	CO5140116A1 (fr)
CZ (1)	CZ301953B6 (fr)
DE (1)	DE69925036T2 (fr)
DK (1)	DK1144411T3 (fr)
EA (1)	EA004500B1 (fr)
EE (1)	EE04917B1 (fr)
EG (1)	EG24605A (fr)
ES (1)	ES2242443T3 (fr)
HK (1)	HK1043128B (fr)
HR (1)	HRP20010453B1 (fr)
HU (1)	HU229406B1 (fr)
ID (1)	ID29268A (fr)
IL (1)	IL143767A0 (fr)
MY (1)	MY129663A (fr)
NO (1)	NO318891B1 (fr)
NZ (1)	NZ512870A (fr)
PL (1)	PL196262B1 (fr)
PT (1)	PT1144411E (fr)
SA (1)	SA00210113B1 (fr)
SI (1)	SI1144411T1 (fr)
SK (1)	SK286158B6 (fr)
TR (1)	TR200101711T2 (fr)
TW (1)	TWI250981B (fr)
UA (1)	UA74537C2 (fr)
WO (1)	WO2000037470A1 (fr)
ZA (1)	ZA200104977B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR0213325A (pt) *	2001-10-15	2004-10-13	Janssen Pharmaceutica Nv	Derivados de 4-fenil-4-[1h-imidazol-2-il]-piperidina substituìda para a redução de dano isquêmico
EA006507B1 (ru) *	2001-10-15	2005-12-29	Янссен Фармацевтика Н.В.	Новые замещенные 4-фенил-4-[1h-имидазол-2-ил] пиперидиновые производные и их применение в качестве селективных непептидных агонистов дельта-опиоидов
US7412768B2 (en) *	2004-05-11	2008-08-19	Alliss George E	Invertible trimmer line spool for a vegetation trimmer apparatus
EP1795527B1 (fr) *	2004-09-07	2009-04-22	Banyu Pharmaceutical Co., Ltd.	Composé spiro substitué par un groupement carbamoyle
CN102015711B (zh)	2008-04-29	2013-05-01	诺瓦提斯公司	用于治疗寄生虫病的螺-吲哚衍生物
US8940742B2 (en)	2012-04-10	2015-01-27	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
PT3052485T (pt)	2013-10-04	2021-10-22	Infinity Pharmaceuticals Inc	Compostos heterocíclicos e suas utilizações
US9751888B2 (en)	2013-10-04	2017-09-05	Infinity Pharmaceuticals, Inc.	Heterocyclic compounds and uses thereof
MX382033B (es)	2014-03-19	2025-03-13	Infinity Pharmaceuticals Inc	Compuestos heterocíclicos para utilizarlos en el tratamiento de trastornos mediados por pi3k-gamma.
KR102431436B1 (ko)	2014-08-29	2022-08-10	테스 파마 에스.알.엘.	α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제
WO2016054491A1 (fr)	2014-10-03	2016-04-07	Infinity Pharmaceuticals, Inc.	Composés hétérocycliques et leurs utilisations
WO2017048702A1 (fr)	2015-09-14	2017-03-23	Infinity Pharmaceuticals, Inc.	Formes solides de dérivés d'isoquinolinone, leur procédé de fabrication, compositions les comprenant et méthodes d'utilisation de celles-ci
WO2017088080A1 (fr)	2015-11-25	2017-06-01	Natural Response S.A.	Procédé d'obtention de saponines à partir de plantes
WO2017161116A1 (fr)	2016-03-17	2017-09-21	Infinity Pharmaceuticals, Inc.	Isotopologues de composés isoquinolinone et quinazolinone et leurs utilisations comme inhibiteurs de la kinase pi3k
WO2017214269A1 (fr)	2016-06-08	2017-12-14	Infinity Pharmaceuticals, Inc.	Composés hétérocycliques et leurs utilisations
KR102806794B1 (ko)	2022-10-14	2025-05-12	지이 일렉트리컬 엔지니어링 컴퍼니., 리미티드.	여과 장치용 커버
KR102806793B1 (ko)	2022-10-14	2025-05-12	지이 일렉트리컬 엔지니어링 컴퍼니., 리미티드.	여과 장치
CN117624052B (zh) *	2024-01-26	2024-04-12	四川益能康生环保科技有限公司	一种用于捕集二氧化碳的离子液体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4464380A (en)	1983-05-25	1984-08-07	Pfizer Inc.	Imidazolidinedione derivatives
PH30434A (en) *	1989-04-07	1997-05-09	Janssen Pharmaceutica Nv	Hydroxyalkylfuranyl derivatives
DE69110685T2 (de) *	1990-10-10	1995-11-09	Schering Corp	Substituierte imidazobenzazepine und imidazopyridoazepine.
IL101850A (en) *	1991-06-13	1996-01-31	Janssen Pharmaceutica Nv	11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
IL101851A (en) *	1991-06-13	1996-05-14	Janssen Pharmaceutica Nv	10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor
US5106844A (en) *	1991-09-10	1992-04-21	Sterling Drug Inc.	Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents
TW382017B (en) *	1995-12-27	2000-02-11	Janssen Pharmaceutica Nv	1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives

1999
- 1999-12-15 EE EEP200100328A patent/EE04917B1/xx unknown
- 1999-12-15 US US09/868,535 patent/US7148214B1/en not_active Expired - Lifetime
- 1999-12-15 TR TR2001/01711T patent/TR200101711T2/xx unknown
- 1999-12-15 BR BR9916371-3A patent/BR9916371A/pt not_active Application Discontinuation
- 1999-12-15 AU AU30412/00A patent/AU764820C/en not_active Expired
- 1999-12-15 HK HK02104999.1A patent/HK1043128B/zh unknown
- 1999-12-15 IL IL14376799A patent/IL143767A0/xx not_active IP Right Cessation
- 1999-12-15 AT AT99964625T patent/ATE294178T1/de active
- 1999-12-15 ID IDW00200101298A patent/ID29268A/id unknown
- 1999-12-15 WO PCT/EP1999/010176 patent/WO2000037470A1/fr not_active Ceased
- 1999-12-15 KR KR1020017005016A patent/KR100598725B1/ko not_active Expired - Lifetime
- 1999-12-15 EA EA200100681A patent/EA004500B1/ru not_active IP Right Cessation
- 1999-12-15 JP JP2000589540A patent/JP4601175B2/ja not_active Expired - Lifetime
- 1999-12-15 PT PT99964625T patent/PT1144411E/pt unknown
- 1999-12-15 CA CA2355939A patent/CA2355939C/fr not_active Expired - Lifetime
- 1999-12-15 HR HR20010453A patent/HRP20010453B1/xx not_active IP Right Cessation
- 1999-12-15 CZ CZ20012069A patent/CZ301953B6/cs not_active IP Right Cessation
- 1999-12-15 NZ NZ512870A patent/NZ512870A/en not_active IP Right Cessation
- 1999-12-15 UA UA2001064351A patent/UA74537C2/uk unknown
- 1999-12-15 ES ES99964625T patent/ES2242443T3/es not_active Expired - Lifetime
- 1999-12-15 SK SK814-2001A patent/SK286158B6/sk not_active IP Right Cessation
- 1999-12-15 EP EP99964625A patent/EP1144411B1/fr not_active Expired - Lifetime
- 1999-12-15 PL PL348295A patent/PL196262B1/pl unknown
- 1999-12-15 CN CNB998147052A patent/CN1258533C/zh not_active Expired - Lifetime
- 1999-12-15 HU HU0104779A patent/HU229406B1/hu unknown
- 1999-12-15 DK DK99964625T patent/DK1144411T3/da active
- 1999-12-15 DE DE69925036T patent/DE69925036T2/de not_active Expired - Lifetime
- 1999-12-15 SI SI9930798T patent/SI1144411T1/xx unknown
- 1999-12-17 CO CO99079021A patent/CO5140116A1/es unknown
- 1999-12-17 AR ARP990106513A patent/AR021888A1/es active IP Right Grant
- 1999-12-17 MY MYPI99005537A patent/MY129663A/en unknown
- 1999-12-17 TW TW088122194A patent/TWI250981B/zh not_active IP Right Cessation
- 1999-12-18 EG EG162699A patent/EG24605A/xx active
2000
- 2000-05-21 SA SA00210113A patent/SA00210113B1/ar unknown
2001
- 2001-05-29 BG BG105546A patent/BG65133B1/bg unknown
- 2001-06-01 NO NO20012710A patent/NO318891B1/no not_active IP Right Cessation
- 2001-06-18 ZA ZA200104977A patent/ZA200104977B/en unknown
2004
- 2004-07-26 US US10/898,844 patent/US7087595B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO20012710D0 (no)	2001-06-01
TR200101711T2 (tr)	2001-12-21
SK8142001A3 (en)	2002-04-04
BR9916371A (pt)	2001-09-18
KR20010075655A (ko)	2001-08-09
SA00210113B1 (ar)	2006-09-13
US7148214B1 (en)	2006-12-12
CN1331694A (zh)	2002-01-16
US7087595B2 (en)	2006-08-08
CZ20012069A3 (cs)	2002-02-13
EP1144411B1 (fr)	2005-04-27
CZ301953B6 (cs)	2010-08-11
HRP20010453A2 (en)	2002-06-30
ID29268A (id)	2001-08-16
JP2002533344A (ja)	2002-10-08
JP4601175B2 (ja)	2010-12-22
IL143767A0 (en)	2002-04-21
NO318891B1 (no)	2005-05-18
HK1043128B (zh)	2007-01-19
PL196262B1 (pl)	2007-12-31
EE200100328A (et)	2002-08-15
NO20012710L (no)	2001-06-01
BG105546A (en)	2001-12-29
PT1144411E (pt)	2005-09-30
CN1258533C (zh)	2006-06-07
AU3041200A (en)	2000-07-12
WO2000037470A8 (fr)	2000-08-24
DE69925036T2 (de)	2006-01-26
AU764820B2 (en)	2003-08-28
EP1144411A1 (fr)	2001-10-17
DK1144411T3 (da)	2005-09-19
CA2355939A1 (fr)	2000-06-29
SI1144411T1 (en)	2005-10-31
CA2355939C (fr)	2010-12-14
HUP0104779A2 (hu)	2002-04-29
TWI250981B (en)	2006-03-11
HUP0104779A3 (en)	2003-12-29
HU229406B1 (en)	2013-12-30
WO2000037470A1 (fr)	2000-06-29
BG65133B1 (bg)	2007-03-30
AR021888A1 (es)	2002-08-07
HK1043128A1 (en)	2002-09-06
US20050026901A1 (en)	2005-02-03
PL348295A1 (en)	2002-05-20
UA74537C2 (uk)	2006-01-16
NZ512870A (en)	2003-11-28
EA004500B1 (ru)	2004-04-29
SK286158B6 (sk)	2008-04-07
ES2242443T3 (es)	2005-11-01
EA200100681A1 (ru)	2001-12-24
ZA200104977B (en)	2002-06-18
EG24605A (en)	2010-01-10
DE69925036D1 (de)	2005-06-02
CO5140116A1 (es)	2002-03-22
KR100598725B1 (ko)	2006-07-11
HRP20010453B1 (hr)	2010-07-31
ATE294178T1 (de)	2005-05-15
AU764820C (en)	2004-11-18
MY129663A (en)	2007-04-30

Legal Events

Date	Code	Title	Description
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231

Publication	Publication Date	Title
EE04917B1 (et)	2007-10-15	Antihistamiinsed spirohendid, vahehendid ja farmatseutiline kompositsioon ning nende valmistamismeetodid ja kasutamine
EE200300207A (et)	2003-08-15	Heterotsüklüülalküülpiperidiini derivaadid, nendevalmistamismeetodid ja farmatseutiline kompositsioon
EE05110B1 (et)	2008-12-15	3-(3-isopropl-5-metl-4H-1,2,4-triasool-4-l)ekso-8-asabitsklo[3.2.1]oktaani derivaadid, selliste derivaatide valmistamismeetodid, nende valmistamisel kasutatavad vahehendid, selliseid derivaatesisaldavad kompositsioonid ja kombinatsioonid ning
EE200300329A (et)	2003-10-15	Meetod peroraalselt manustatavate epotiloonide biosaadavuse suurendamiseks ning selles kasutatav komplekt, ravimkoostis ja farmatseutiline ravimvorm
EE05086B1 (et)	2008-10-15	Primidiini derivaadid, nende valmistamismeetod ja kasutamine, farmatseutiline kompositsioon ja selle valmistamismeetod, kombinatsioon ning saadus
EE05104B1 (et)	2008-12-15	Asetidiini derivaadid, nende valmistamise meetodid ja farmatseutiline kompositsioon
EE04915B1 (et)	2007-10-15	Kinuklidiinderivaadid, nende valmistamismeetod, vahehendid, farmatseutiline kompositsioon ja nende kasutamine
EE200200118A (et)	2003-04-15	Terapeutilised kinasoliini derivaadid, nende valmistamise meetod ning kasutamine
EE04178B1 (et)	2003-12-15	3- või 4-asendatud 4-(aminometüül)piperidiini bitsüklilised bensamiidid, vaheühend ja farmatseutiline kompositsioon ning nende valmistamismeetodid
EE05170B1 (et)	2009-06-15	Asabitskloalkaanid kui CCR5 modulaatorid, neid sisaldavad farmatseutilised kompositsioonid ja kombinatsioonid ning nende meditsiiniline kasutamine
EE200000319A (et)	2001-08-15	hGRF-PEG konjugaatide saitspetsiifiline valmistamismeetod, hGRF-PEG konjugaadid, nende vaheühendid, kasutamine ja farmatseutiline kompositsioon
EE04799B1 (et)	2007-04-16	Ühendid, mis on kasulikud põletikuvastaste vahenditena, nende ühendite valmistamise meetodid ja neid sisaldavad farmatseutilised kompositsioonid
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EE04917B1 - Antihistamiinsed spirohendid, vahehendid ja farmatseutiline kompositsioon ning nende valmistamismeetodid ja kasutamine - Google Patents