EE05333B1 - Makroliidhendite konjugaadid p?letikuvastaste henditega ja nende kasutamine - Google Patents

Makroliidhendite konjugaadid p?letikuvastaste henditega ja nende kasutamine

Info

Publication number: EE05333B1
Authority: EE; Estonia
Prior art keywords: conjugates; inflammatory agents; macrolide compounds; macrolide; compounds
Prior art date: 2001-01-09

Application number

EEP200300293A

Other languages

English (en)

Estonian (et)

Inventor

Mercep Mladen

Mesic Milan

Tomaskovic Linda

Komac Marijana

Hrvacic Boska

Markovic Stribor

Original Assignee

Pliva D.D.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-09

Filing date

2002-01-03

Publication date

2010-08-16

2002-01-03 Application filed by Pliva D.D. filed Critical Pliva D.D.

2003-10-15 Publication of EE200300293A publication Critical patent/EE200300293A/xx

2010-08-16 Publication of EE05333B1 publication Critical patent/EE05333B1/xx

Links

229940121363 anti-inflammatory agent Drugs 0.000 title 1
239000002260 anti-inflammatory agent Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000003120 macrolide antibiotic agent Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Pulmonology (AREA)
Immunology (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EEP200300293A 2001-01-09 2002-01-03 Makroliidhendite konjugaadid p?letikuvastaste henditega ja nende kasutamine EE05333B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HR20010018A HRP20010018A2 (en)	2001-01-09	2001-01-09	Novel anti-inflammatory compounds
PCT/HR2002/000001 WO2002055531A1 (en)	2001-01-09	2002-01-03	Conjugates of immune cell specific macrolide compounds with anti-inflammatory compounds for improved cellular targeting of anti-inflammatory therapy

Publications (2)

Publication Number	Publication Date
EE200300293A EE200300293A (et)	2003-10-15
EE05333B1 true EE05333B1 (et)	2010-08-16

Family

ID=10947235

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300293A EE05333B1 (et)	2001-01-09	2002-01-03	Makroliidhendite konjugaadid p?letikuvastaste henditega ja nende kasutamine

Country Status (23)

Country	Link
US (2)	US7446097B2 (pl)
EP (1)	EP1351973B1 (pl)
JP (1)	JP4474101B2 (pl)
CN (1)	CN1269836C (pl)
AR (1)	AR035727A1 (pl)
AT (1)	ATE462713T1 (pl)
BG (1)	BG108073A (pl)
BR (1)	BR0206347A (pl)
CA (1)	CA2434009C (pl)
CZ (1)	CZ20031825A3 (pl)
DE (1)	DE60235794D1 (pl)
EA (1)	EA007061B1 (pl)
EE (1)	EE05333B1 (pl)
ES (1)	ES2342364T3 (pl)
GE (1)	GEP20053607B (pl)
HR (1)	HRP20010018A2 (pl)
HU (1)	HUP0500180A3 (pl)
IL (1)	IL156673A0 (pl)
PL (1)	PL207636B1 (pl)
RS (1)	RS51308B (pl)
SK (1)	SK9792003A3 (pl)
UA (1)	UA77166C2 (pl)
WO (1)	WO2002055531A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2002109169A (ja) *	2000-09-29	2002-04-12	Hitachi Ltd	作業支援方法並びにシステム及び作業支援方法を記録した記録媒体
AU2003219770B2 (en)	2002-02-15	2008-10-09	Merckle Gmbh	Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
US7271154B2 (en)	2002-02-15	2007-09-18	Merckle Gmbh	Antibiotic conjugates
EP1483579A4 (en)	2002-02-15	2006-07-12	Merckle Gmbh	CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS, PROCESS FOR THEIR MANUFACTURE AND USE, FORMULATION AND PHARMACEUTICAL APPLICATIONS THEREOF
EP1521763A2 (en) *	2002-07-08	2005-04-13	Pliva - Istrazivacki Institut d.o.o.	Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use
AU2003264917A1 (en)	2002-07-08	2004-01-23	Pliva - Istrazivacki Institut D.O.O.	Hybrid molecules of macrolides with steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
RS20050008A (sr) *	2002-07-08	2007-06-04	Pliva-Istraživački Institut D.O.O.,	Nova jedinjenja,kompozicije i metode za lečenje inflamatornih oboljenja i stanja
HRP20030324A2 (en)	2003-04-24	2005-02-28	Pliva-Istra�iva�ki institut d.o.o.	Compounds of antiinflammatory effect
WO2005030227A1 (en)	2003-09-23	2005-04-07	Enanta Pharmaceuticals, Inc.	9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
JP4737495B2 (ja) *	2004-01-14	2011-08-03	塩野義製薬株式会社	エリスロマイシン誘導体
KR20070046917A (ko) *	2004-08-12	2007-05-03	글락소스미쓰클라인 이스트라지바치키 센타 자그레브 디.오.오.	위장관의 염증성 질환의 치료를 위한 세포-특이적컨쥬게이트의 용도
US20060183696A1 (en) *	2004-08-12	2006-08-17	Pliva-Istrazivacki Institut D.O.O.	Use of immune cell specific conjugates for treatment of inflammatory diseases of gastrointestinal tract
US7402568B2 (en)	2004-09-29	2008-07-22	Enanta Pharmaceuticals, Inc.	Bicyclic 9a-azalide derivatives
ES2337915T3 (es) *	2004-10-27	2010-04-30	Glaxosmithkline Istrazivacki Centar Zagreb D.O.O.	Conjugados con adtividad antiinflamatoria.
US7271155B2 (en)	2005-01-07	2007-09-18	Enanta Pharmaceuticals, Inc.	9A, 11-2C-bicyclic 9a-azalide derivatives
US20080249034A1 (en) *	2005-03-21	2008-10-09	Zambon S.P.A.	Use of Macrolides for Treating Intestinal Inflammation
WO2011116312A1 (en) *	2010-03-19	2011-09-22	Catabasis Pharmaceuticals, Inc.	Fatty acid macrolide derivatives and their uses
EP2948152A4 (en) *	2013-01-23	2016-12-14	Sphaera Pharma Private Ltd	NOVEL COMPOUNDS OF 11-BETA HYDROXY-STEROIDS FOR USE IN MITOCHONDRIA BIOGENESIS AND DISEASES RELATED TO MITOCHONDRIA DYSFUNCTION OR ADDITIONAL
WO2016013030A2 (en)	2014-07-23	2016-01-28	Sphaera Pharma Pvt. Ltd.	Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof
GB201520419D0 (en)	2015-11-19	2016-01-06	Epi Endo Pharmaceuticals Ehf	Compounds
WO2023248010A2 (en) *	2022-06-23	2023-12-28	Synovo Gmbh	Targeted modulators of jak3 for treatment of inflammatory and autoimmune diseases

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4710495A (en)	1980-07-10	1987-12-01	Otsuka Pharmaceutical Co., Ltd.	Soft steroids having anti-inflammatory activity
HU198913B (en)	1987-09-03	1989-12-28	Pliva Pharm & Chem Works	Process for producing 10-dihydro-10-deoxo-11-aza-erythronolide a-derivatives and pharmaceutical compositions containing them as active components
JPH01163124A (ja) *	1987-12-21	1989-06-27	Yamayuu Seikatsushiya:Kk	外用鎮痛消炎消腫消膿剤
SE9100342D0 (sv)	1991-02-04	1991-02-04	Astra Ab	Novel steroid esters
SE9100341D0 (sv)	1991-02-04	1991-02-04	Astra Ab	Novel steroids
GB9225923D0 (en)	1992-12-11	1993-02-03	Rhone Poulenc Rorer Ltd	New compositions of matter
DE69311742T2 (de)	1992-12-24	1998-01-08	Rhone Poulenc Rorer Ltd	Neue steroide
AU3192695A (en)	1994-08-12	1996-03-07	Taisho Pharmaceutical Co., Ltd.	Interleukin-5 production inhibitor
WO1996004919A1 (en)	1994-08-12	1996-02-22	Taisho Pharmaceutical Co., Ltd.	Interleukin-5 production inhibitor
DE19542949A1 (de)	1995-11-17	1997-07-17	Hilti Ag	Bolzen zum Eintreiben in harte Aufnahmewerkstoffe
CA2252886C (en)	1996-04-26	2008-02-12	Massachusetts Institute Of Technology	Three-hybrid screening assay
FR2776927B1 (fr) *	1998-04-07	2002-07-05	Univ Paris Curie	Compositions pour la vectorisation de molecules
US6288234B1 (en) *	1998-06-08	2001-09-11	Advanced Medicine, Inc.	Multibinding inhibitors of microsomal triglyceride transferase protein
WO1999064040A1 (en) *	1998-06-08	1999-12-16	Advanced Medicine, Inc.	Novel polyene macrolide compounds and uses
IT1306205B1 (it)	1999-01-15	2001-05-30	Zambon Spa	Macrolidi ad attivita' antiinfiammatoria.
AU2003219770B2 (en)	2002-02-15	2008-10-09	Merckle Gmbh	Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof

2001
- 2001-01-09 HR HR20010018A patent/HRP20010018A2/hr not_active Application Discontinuation
2002
- 2002-01-03 EP EP02729470A patent/EP1351973B1/en not_active Expired - Lifetime
- 2002-01-03 HU HU0500180A patent/HUP0500180A3/hu unknown
- 2002-01-03 PL PL363478A patent/PL207636B1/pl unknown
- 2002-01-03 DE DE60235794T patent/DE60235794D1/de not_active Expired - Lifetime
- 2002-01-03 JP JP2002556599A patent/JP4474101B2/ja not_active Expired - Fee Related
- 2002-01-03 EE EEP200300293A patent/EE05333B1/xx not_active IP Right Cessation
- 2002-01-03 AT AT02729470T patent/ATE462713T1/de not_active IP Right Cessation
- 2002-01-03 US US10/250,934 patent/US7446097B2/en not_active Expired - Fee Related
- 2002-01-03 IL IL15667302A patent/IL156673A0/xx unknown
- 2002-01-03 SK SK979-2003A patent/SK9792003A3/sk unknown
- 2002-01-03 EA EA200300781A patent/EA007061B1/ru not_active IP Right Cessation
- 2002-01-03 CN CNB02804715XA patent/CN1269836C/zh not_active Expired - Fee Related
- 2002-01-03 BR BR0206347-6A patent/BR0206347A/pt not_active Application Discontinuation
- 2002-01-03 CZ CZ20031825A patent/CZ20031825A3/cs unknown
- 2002-01-03 ES ES02729470T patent/ES2342364T3/es not_active Expired - Lifetime
- 2002-01-03 CA CA002434009A patent/CA2434009C/en not_active Expired - Fee Related
- 2002-01-03 GE GE5260A patent/GEP20053607B/en unknown
- 2002-01-03 RS YUP-552/03A patent/RS51308B/sr unknown
- 2002-01-03 WO PCT/HR2002/000001 patent/WO2002055531A1/en not_active Ceased
- 2002-01-08 AR ARP020100040A patent/AR035727A1/es active IP Right Grant
- 2002-03-01 UA UA2003076135A patent/UA77166C2/uk unknown
2003
- 2003-08-07 BG BG108073A patent/BG108073A/bg unknown
2008
- 2008-09-16 US US12/211,213 patent/US7928078B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20040198677A1 (en)	2004-10-07
CA2434009A1 (en)	2002-07-18
IL156673A0 (en)	2004-01-04
HK1065320A1 (en)	2005-02-18
ATE462713T1 (de)	2010-04-15
SK9792003A3 (en)	2004-01-08
WO2002055531A1 (en)	2002-07-18
EE200300293A (et)	2003-10-15
HRP20010018A2 (en)	2002-12-31
EP1351973B1 (en)	2010-03-31
CZ20031825A3 (cs)	2003-11-12
CN1491230A (zh)	2004-04-21
YU55203A (sh)	2006-03-03
AR035727A1 (es)	2004-07-07
HUP0500180A2 (en)	2006-09-28
ES2342364T3 (es)	2010-07-06
PL207636B1 (pl)	2011-01-31
HUP0500180A3 (en)	2009-12-28
CA2434009C (en)	2009-09-29
DE60235794D1 (de)	2010-05-12
JP4474101B2 (ja)	2010-06-02
US7446097B2 (en)	2008-11-04
GEP20053607B (en)	2005-09-12
EA007061B1 (ru)	2006-06-30
UA77166C2 (en)	2006-11-15
US7928078B2 (en)	2011-04-19
EA200300781A1 (ru)	2003-12-25
EP1351973A1 (en)	2003-10-15
PL363478A1 (pl)	2004-11-15
BR0206347A (pt)	2004-02-10
CN1269836C (zh)	2006-08-16
BG108073A (bg)	2005-05-31
RS51308B (sr)	2010-12-31
US20090105163A1 (en)	2009-04-23
JP2004518670A (ja)	2004-06-24

Legal Events

Date	Code	Title	Description
2005-02-15	GB1A	Change in the ownership or in the address of the owner
2010-04-15	HB1A	Correction of owner name or address
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2012-10-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20120103

Publication	Publication Date	Title
EE05333B1 (et)	2010-08-16	Makroliidhendite konjugaadid p?letikuvastaste henditega ja nende kasutamine
EE200200251A (et)	2003-06-16	Uued N-asabitsükloamiidi derivaadid ja nende kasutamine
ID30590A (id)	2002-01-03	Celana sekali pakai jenis-celana pendek
EE200300145A (et)	2003-06-16	Asa- ja polüasanaftalenüülkarboksamiidid ja farmatseutiline kompositsioon
EE200200715A (et)	2004-08-16	Asendatud kinasoliini derivaadid ja nende kasutamine inhibiitoritena
EP1333834A4 (en)	2007-01-17	ANTIPHLOGISTIC MEANS
AR027938A1 (es)	2003-04-16	Compuestos uracilo y utilizacion de los mismos
DE60208351D1 (de)	2006-02-02	Glukopyranosyloxybenzylbenzolderivate und deren medizinische verwendung
DE60230591D1 (de)	2009-02-12	Glykopyranosyloxypyrazolderivate und deren medizinische verwendung
EE05169B1 (et)	2009-06-15	Asendatud oksasolidinoonid ja nende kasutamine
AR028567A1 (es)	2003-05-14	Nuevos derivados de fenil-propargileter
FR2803516B1 (fr)	2003-03-28	Formulation injectable de fulvestrant
EP1298180A4 (en)	2005-03-09	HYDROPHOBIC AND LIPOPHOBE COMPOSITION
NO20031407D0 (no)	2003-03-27	Glukopyranosyloksybenzylbenzen-derivater og medisinske sammensetninger inneholdende det samme
EE200200607A (et)	2004-04-15	2-atsüülindoolderivaadid ja nende kasutamine kasvajavastaste ravimitena
EE05020B1 (et)	2008-06-16	Glburiidi ravimkoostis
AR028596A1 (es)	2003-05-14	Nuevos derivados de fenilglicina
BRPI0208558A2 (pt)	2017-05-23	preparado de combinação de estrogênio-gestagênio e uso
EE200200626A (et)	2004-04-15	Antraniilamiidid ja nende kasutamine ravimitena
ID30187A (id)	2001-11-15	Dongkrak jenis pantagraf
FI20011671A0 (fi)	2001-08-20	Tuumorispesifiset oligosakkaridisekvenssit ja niiden käyttö
EE05537B1 (et)	2012-04-16	Neublastiini polmeerkonjugaadid ja meetodid nende kasutamiseks
DE60109003D1 (de)	2005-03-31	Viskose und Amin-gehärtete Dübelmasse
PT1322592E (pt)	2004-12-31	Derivados substituidos de 1-aminobutan-3-ol
DE60117096D1 (de)	2006-04-20	Dihydroindol- und tetrahydrochinolinderivate

EE05333B1 - Makroliidhendite konjugaadid p?letikuvastaste henditega ja nende kasutamine - Google Patents