EE05675B1 - Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade - Google Patents

Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade

Info

Publication number
EE05675B1
EE05675B1 EEP200300005A EEP200300005A EE05675B1 EE 05675 B1 EE05675 B1 EE 05675B1 EE P200300005 A EEP200300005 A EE P200300005A EE P200300005 A EEP200300005 A EE P200300005A EE 05675 B1 EE05675 B1 EE 05675B1
Authority
EE
Estonia
Prior art keywords
diagnosis
detection
test procedure
reagent kit
required test
Prior art date
Application number
EEP200300005A
Other languages
English (en)
Estonian (et)
Inventor
Soto Claudio
Saborio Gabriella
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of EE200300005A publication Critical patent/EE200300005A/xx
Publication of EE05675B1 publication Critical patent/EE05675B1/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200300005A 2000-07-07 2001-06-13 Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade EE05675B1 (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP00114650 2000-07-07
EP00127892 2000-12-20
EP01102732 2001-02-07
PCT/GB2001/002584 WO2002004954A2 (en) 2000-07-07 2001-06-13 Early diagnosis of conformational diseases

Publications (2)

Publication Number Publication Date
EE200300005A EE200300005A (et) 2004-08-16
EE05675B1 true EE05675B1 (et) 2013-08-15

Family

ID=27223071

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300005A EE05675B1 (et) 2000-07-07 2001-06-13 Meetod konformse haiguse diagnoosimiseks v?i tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade

Country Status (30)

Country Link
US (1) US7351526B2 (de)
EP (2) EP1712920B1 (de)
JP (1) JP4790966B2 (de)
KR (1) KR100764981B1 (de)
CN (1) CN1221807C (de)
AR (1) AR029583A1 (de)
AT (2) ATE335204T1 (de)
AU (2) AU6408901A (de)
BG (1) BG66272B1 (de)
BR (1) BRPI0112262B8 (de)
CA (1) CA2413078C (de)
CY (1) CY1109106T1 (de)
CZ (1) CZ304365B6 (de)
DE (2) DE60121958T2 (de)
DK (2) DK1712920T3 (de)
EA (1) EA007391B1 (de)
EE (1) EE05675B1 (de)
ES (2) ES2322660T3 (de)
HR (1) HRP20030033B1 (de)
HU (1) HU228813B1 (de)
IL (2) IL153824A0 (de)
MX (1) MXPA03000226A (de)
NO (1) NO331624B1 (de)
NZ (1) NZ523213A (de)
PL (1) PL211154B1 (de)
PT (2) PT1712920E (de)
RS (1) RS51523B (de)
SI (2) SI1712920T1 (de)
SK (1) SK287768B6 (de)
WO (1) WO2002004954A2 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002073210A1 (de) * 2001-03-13 2002-09-19 Manfred Eigen Verfahren zur verstärkung der bildung von aggregaten aus proteinuntereinheiten
AU2002320045B2 (en) 2001-05-31 2008-05-08 Adlyfe, Inc. Misfolded protein sensor method
US20050026165A1 (en) * 2001-05-31 2005-02-03 Cindy Orser Detection of conformationally altered proteins and prions
EP1636592B1 (de) 2003-06-19 2012-12-19 Merck Serono SA Verwendung von prion-umwandlung modulierende mittel
DE10328125A1 (de) * 2003-06-23 2005-01-13 Roche Diagnostics Gmbh Nachweis von Protease-resistentem Prion-Protein nach spontaner Transformationsreaktion
DE10328830A1 (de) * 2003-06-26 2005-01-20 Roche Diagnostics Gmbh Nachweis von Protease-resistentem Prion-Protein nach asymmetrischer Interaktion
WO2005010533A2 (en) * 2003-07-31 2005-02-03 Hadasit Medical Research Services & Development Ltd. Methods and kits for the detection of prion diseases
ES2398394T3 (es) 2003-08-13 2013-03-15 Novartis Vaccines And Diagnostics, Inc. Reactivos peptídicos específicos de prión
US20060057671A1 (en) * 2004-09-10 2006-03-16 Orser Cindy S Immobilized probes and methods of detecting conformationally altered prion proteins
JP4568840B2 (ja) * 2004-12-28 2010-10-27 国立大学法人金沢大学 アルツハイマー病の検査方法
EP1853915B1 (de) * 2005-02-15 2011-10-12 Adlyfe, Inc. Verfahren zum nachweis falsch gefalteter proteine und prionen
JP2008537155A (ja) * 2005-04-20 2008-09-11 ボード オブ リージェンツ ザ ユニバーシティー オブ テキサス システム 自動化タンパク質異常折り畳みの周期的増幅によるプリオンの超高感度検出
EP1731911A1 (de) * 2005-06-07 2006-12-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Verfahren zum Nachweis von Enzephalopathien
DE102005031429A1 (de) * 2005-07-04 2007-01-11 Heinrich-Heine-Universität Düsseldorf Verfahren zur selektiven Bestimmung pathologischer Proteinablagerungen
WO2007030804A1 (en) 2005-09-09 2007-03-15 Novartis Ag Prion-specific peptoid reagents
US20070281367A1 (en) 2006-05-03 2007-12-06 Applera Corporation Methods, Compositions, and Kits for Quantitating Antibodies
JP5097206B2 (ja) 2006-07-28 2012-12-12 エイディーライフ インコーポレイティッド 診断および治療のためのペプチドプローブ
WO2008030973A2 (en) * 2006-09-06 2008-03-13 The Board Of Regents Of The University Of Texas System Methods and compositions for the detection of protein folding disorders
EP2554996B1 (de) * 2007-07-20 2016-04-06 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Nachweis eines infektiösen Prionenproteins mittels beimpfter Umwandlung eines rekombinanten Prionenproteins
FR2929290B1 (fr) * 2008-03-27 2010-05-07 Lfb Biotechnologies Methode de detection et/ou de titrage in vitro d'un agent transmissible non conventionnel
WO2009145194A1 (ja) 2008-05-28 2009-12-03 独立行政法人農業・食品産業技術総合研究機構 羊スクレイピー由来異常プリオン蛋白質の効率的増幅方法
AU2009252392B2 (en) 2008-05-28 2012-02-02 Incorporated Administrative Agency National Agriculture And Food Research Organization Method for efficiently amplifying abnormal prion protein derived from BSE
ITMI20081052A1 (it) * 2008-06-10 2009-12-11 Univ Milano Bicocca Liposomi in grado di legare efficacemente il peptide beta-amiloide
FR2935711A1 (fr) * 2008-09-05 2010-03-12 Lfb Biotechnologies Clone cellulaire stable exprimant un prion
CN102725639A (zh) * 2009-11-04 2012-10-10 诺华有限公司 蛋白质聚集物与单体分离中作为结合试剂的带正电物质
US10989718B2 (en) 2014-09-11 2021-04-27 Amprion, Inc. Detection of misfolded alpha synuclein protein
US10215763B2 (en) * 2010-05-18 2019-02-26 Board Of Regents Of The University Of Texas System Methods for estimating prion concentration in fluids and tissue by quantitative PMCA
IT1405762B1 (it) 2010-11-25 2014-01-24 Icgeb Proteine ricombinanti con attivita' di inattivazione selettiva di proteine bersaglio
CA2824863A1 (en) * 2011-01-18 2012-07-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods for amplification and detection of prions
FR2973114A1 (fr) 2011-03-21 2012-09-28 Ets Francais Du Sang Nanobilles recouvertes de plasminogene comme support direct d'amplification cyclique de la proteine prion prpsc
WO2013056841A1 (en) 2011-10-19 2013-04-25 Inra (Institut National De La Recherche Agronomique) A method for diagnosing tse
WO2015160007A1 (ko) * 2014-04-17 2015-10-22 한림대학교 산학협력단 극미량 병원성 프리온 단백질 검출방법 및 장치
EP3191599B1 (de) 2014-09-11 2023-08-02 Board Of Regents Of the University Of Texas System Detektion von fehlgefalteten proteinen
WO2016040903A1 (en) 2014-09-11 2016-03-17 Board Of Regents Of The University Of Texas System Detection of misfolded amyloid beta protein
US10359434B2 (en) 2014-10-22 2019-07-23 Colorado State University Research Foundation In vitro detection of prions in blood
WO2016149537A1 (en) 2015-03-17 2016-09-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
KR20200007945A (ko) 2017-05-16 2020-01-22 암프리온, 인코퍼레이티드 미스폴딩된 타우 단백질의 검출
WO2019222554A2 (en) * 2018-05-16 2019-11-21 Amprion, Inc. Detection of brain injury or neurological disease using tau protein
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
KR102793756B1 (ko) 2019-09-04 2025-04-08 암프리온, 인코퍼레이티드 비드를 사용한 알파-시누클레인 검출
US11598783B1 (en) 2019-10-23 2023-03-07 Colorado State University Research Foundation In vitro detection of prions
WO2021198098A1 (en) * 2020-04-03 2021-10-07 Universität Zürich Improved method of detecting biomarkers in a biological sample
CN120367833B (zh) * 2025-04-26 2026-02-24 浙江青霄科技股份有限公司 一种潜水泵

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262332A (en) 1989-04-05 1993-11-16 Brigham And Women's Hospital Diagnostic method for Alzheimer's disease: examination of non-neural tissue
US5616871A (en) * 1995-09-28 1997-04-01 Drummond Scientific Company Pipet gun assembly
US5750361A (en) * 1995-11-02 1998-05-12 The Regents Of The University Of California Formation and use of prion protein (PRP) complexes
EP0934531B1 (de) 1996-10-15 2004-08-04 D-Gen Limited Diagnose spongiformer encephalopathie
WO2001000235A1 (en) * 1999-06-29 2001-01-04 Mcgill University Prion protein binding proteins and uses thereof
CA2393607A1 (en) 1999-12-10 2001-06-28 Ronald R. Manna Ultrasonic horn assembly
JP2008537155A (ja) * 2005-04-20 2008-09-11 ボード オブ リージェンツ ザ ユニバーシティー オブ テキサス システム 自動化タンパク質異常折り畳みの周期的増幅によるプリオンの超高感度検出

Also Published As

Publication number Publication date
BG107498A (bg) 2003-11-28
HRP20030033A2 (en) 2004-02-29
MXPA03000226A (es) 2004-05-21
SK287768B6 (sk) 2011-09-05
EE200300005A (et) 2004-08-16
AR029583A1 (es) 2003-07-02
PL360397A1 (en) 2004-09-06
CY1109106T1 (el) 2014-07-02
NO20030059L (no) 2003-03-07
BR0112262A (pt) 2003-05-20
EP1299729B1 (de) 2006-08-02
JP2004503748A (ja) 2004-02-05
YU101202A (sh) 2006-01-16
HUP0301020A3 (en) 2010-03-29
BG66272B1 (bg) 2012-11-30
CN1449497A (zh) 2003-10-15
AU2001264089B2 (en) 2006-03-30
HU228813B1 (en) 2013-05-28
US7351526B2 (en) 2008-04-01
DE60121958T2 (de) 2007-02-01
CA2413078C (en) 2010-08-03
WO2002004954A3 (en) 2002-10-24
KR20030036257A (ko) 2003-05-09
EA007391B1 (ru) 2006-10-27
HUP0301020A2 (hu) 2003-07-28
CZ200336A3 (cs) 2003-06-18
NO20030059D0 (no) 2003-01-06
HK1058065A1 (en) 2004-04-30
HRP20030033B1 (hr) 2008-04-30
EP1712920B1 (de) 2009-03-25
ATE335204T1 (de) 2006-08-15
ES2322660T3 (es) 2009-06-24
EA200300126A1 (ru) 2003-06-26
PT1299729E (pt) 2006-10-31
CA2413078A1 (en) 2002-01-17
ATE426816T1 (de) 2009-04-15
BRPI0112262B8 (pt) 2021-07-27
NZ523213A (en) 2005-01-28
DE60121958D1 (de) 2006-09-14
ES2264691T3 (es) 2007-01-16
EP1712920A1 (de) 2006-10-18
US20050064505A1 (en) 2005-03-24
SI1299729T1 (sl) 2006-10-31
DK1712920T3 (da) 2009-05-11
SI1712920T1 (sl) 2009-10-31
IL153824A (en) 2010-02-17
BRPI0112262B1 (pt) 2016-08-09
PT1712920E (pt) 2009-04-09
IL153824A0 (en) 2003-07-31
NO331624B1 (no) 2012-02-06
AU6408901A (en) 2002-01-21
RS51523B (sr) 2011-06-30
WO2002004954A2 (en) 2002-01-17
KR100764981B1 (ko) 2007-10-09
DE60138146D1 (de) 2009-05-07
CZ304365B6 (cs) 2014-04-02
DK1299729T3 (da) 2006-12-04
PL211154B1 (pl) 2012-04-30
JP4790966B2 (ja) 2011-10-12
CN1221807C (zh) 2005-10-05
SK18582002A3 (sk) 2003-05-02
EP1299729A2 (de) 2003-04-09

Similar Documents

Publication Publication Date Title
EE200300005A (et) Meetod konformse haiguse diagnoosimiseks või tuvastamiseks, selleks vajalik katsemenetlus, reaktiivikomplekt ning seade
ITRM20030386A0 (it) Metodo e test diagnostici basati sull'analisi citofluorimetrica dei linfociti t antigene-specifici.
DK1266608T3 (da) Biologisk væskeprövetagnings- og analytmåleindretning
NO20025702L (no) Todelt stråle FTIR-metoder og anordning for anvendelse i analyttdeteksjon ipröver med lav transmissivitet
FI20011877L (fi) Menetelmä ja bioanturi analyysiä varten
EE200300128A (et) Meetod allergeeniga seostuva immunoglobuliini detekteerimiseks proovis, patsiendi allergiate in vitro diagnoosimeetod, mikromaatrikskiip ja komplekt
DE602004018575D1 (de) Chirurgisches Ultraschallsystem und Probe
ATE514945T1 (de) Diagnoseverfahren für maul- und klauenseuche und diagnostischer kit
DE60141171D1 (de) Klinische intelligente diagnostische vorrichtungen und verfahren
DE60043049D1 (de) Bluttestvorrichtung
FI990559A7 (fi) Näytteenkäsittelymenetelmä ja diagnostinen mittauslaite
DE60223635D1 (de) Reagenzien, Verfahren und Vorrichtungen zum Nachweis von Analyten
EP1625386A4 (de) Vorrichtungen und verfahren zum nachweis von analytkonzentrationen
DE60030756D1 (de) Körperflüssigkeitsmessinstrument und körperflüssigkeitsprobeentnahmegerät
NO20034777L (no) Anordning for måling av blodglukosekonsentrasjoner
DE50202018D1 (de) Intrakorporale sonde zur analyse oder diagnose und/oder therapie
DE60133982D1 (de) Biosensor und verfahren zum analysieren von blutkomponenten
DE69821865D1 (de) Ultraschall-Diagnosegerät, Verfahren zur Cursor-Darstellung, und Messgerät
ZA200700525B (en) Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
EP1643894A4 (de) Verfahren, kits und antikörper zum nachweis von parathyroid
FR2810444B1 (fr) Dispositif de collimation, appareil de radiologie, kit de test et procede de test d'un appareil de radiologie
AU2003289853A8 (en) Methods, device and instrument for detection of analytes
EP1372473A4 (de) Gerät und verfahren für den nachweis und die quantifizierung von oszillationsignalen
DE60037595D1 (de) Vorrichtung zur zerstörungsfreien prüfung
DE19983966T1 (de) Immunodiagnostisches Testverfahren für eine Tierkrankheit

Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
HC1A Change of owner name