EE200000657A - Asoolid, nende valmistamismeetod, kasutamine ravimina ja farmatseutiline kompositsioon - Google Patents

Asoolid, nende valmistamismeetod, kasutamine ravimina ja farmatseutiline kompositsioon

Info

Publication number: EE200000657A
Authority: EE; Estonia
Prior art keywords: pharmaceutical; azoles; preparation; pharmaceutical composition; composition
Prior art date: 1998-05-14

Application number

EEP200000657A

Other languages

English (en)

Inventor

Jozef Elisabeth Van Der Veken Louis

Meerpoel Lieven

Jacobus Josef Backx Leo

Christopher Odds Frank

Heeres Jan

Original Assignee

Janssen Pharmaceutica N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-05-14

Filing date

1999-05-06

Publication date

2002-04-15

1999-05-06 Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.

2002-04-15 Publication of EE200000657A publication Critical patent/EE200000657A/et

2004-06-15 Publication of EE04311B1 publication Critical patent/EE04311B1/et

Links

150000003851 azoles Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

EEP200000657A 1998-05-14 1999-05-06 Asoolid, nende valmistamismeetod, kasutamine ravimina ja farmatseutiline kompositsioon EE04311B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98201588A EP0957101A1 (en)	1998-05-14	1998-05-14	Water soluble azoles as broad-spectrum antifungals
PCT/EP1999/003243 WO1999058530A1 (en)	1998-05-14	1999-05-06	Water soluble azoles as broad-spectrum antifungals

Publications (2)

Publication Number	Publication Date
EE200000657A true EE200000657A (et)	2002-04-15
EE04311B1 EE04311B1 (et)	2004-06-15

Family

ID=8233724

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
EEP200000651A EE04346B1 (et)	1998-05-14	1999-05-06	Asoolid, nende valmistamismeetod, kasutamine ja farmatseutiline kompositsioon
EEP200000657A EE04311B1 (et)	1998-05-14	1999-05-06	Asoolid, nende valmistamismeetod, kasutamine ravimina ja farmatseutiline kompositsioon

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
EEP200000651A EE04346B1 (et)	1998-05-14	1999-05-06	Asoolid, nende valmistamismeetod, kasutamine ja farmatseutiline kompositsioon

Country Status (31)

Country	Link
US (2)	US6384030B1 (et)
EP (3)	EP0957101A1 (et)
JP (2)	JP2002514645A (et)
KR (2)	KR100575147B1 (et)
CN (2)	CN1135229C (et)
AR (2)	AR016482A1 (et)
AT (2)	ATE221884T1 (et)
AU (2)	AU758876B2 (et)
BG (2)	BG64388B1 (et)
BR (2)	BR9910448A (et)
CA (2)	CA2331141C (et)
CO (1)	CO5021227A1 (et)
CZ (2)	CZ299481B6 (et)
DE (2)	DE69907171T2 (et)
DK (1)	DK1077976T3 (et)
EE (2)	EE04346B1 (et)
ES (2)	ES2198915T3 (et)
HR (2)	HRP20000741B1 (et)
HU (2)	HUP0103536A3 (et)
IL (2)	IL139647A0 (et)
MY (2)	MY120248A (et)
NO (2)	NO319851B1 (et)
NZ (2)	NZ507965A (et)
PL (2)	PL194086B1 (et)
PT (1)	PT1077976E (et)
SI (1)	SI1077976T1 (et)
SK (2)	SK286156B6 (et)
TR (2)	TR200003322T2 (et)
TW (2)	TWI259835B (et)
WO (2)	WO1999058529A1 (et)
ZA (2)	ZA200007173B (et)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0957101A1 (en) *	1998-05-14	1999-11-17	Janssen Pharmaceutica N.V.	Water soluble azoles as broad-spectrum antifungals
AU3402301A (en) *	2000-03-07	2001-09-17	Ranbaxy Laboratories Limited	Azole compounds as therapeutic agents for fungal infections
EP1413301A1 (fr) *	2002-10-24	2004-04-28	Bayer CropScience SA	Médicaments antifongiques à base de dérivés d'arylamidine
ITMI20032020A1 (it) *	2003-10-17	2005-04-18	Italfarmaco Spa	Nuovi agenti antifungini azolici con diminuita interazione con i citocromi metabolici
AR052342A1 (es) *	2004-12-21	2007-03-14	Janssen Pharmaceutica Nv	Derivados sustituidos de triazolona,tetrazolona e imidazolona con actividad selectiva antagonista de alfa2c-adenoreceptores
CN102906087B (zh) *	2010-05-19	2016-03-23	桑多斯股份公司	制备手性三唑酮的方法
US11028078B2 (en)	2011-09-07	2021-06-08	The Johns Hopkins University	Itraconazole analogs and use thereof
US9346791B2 (en)	2011-09-07	2016-05-24	The Johns Hopkins University	Itraconazole analogs and use thereof
KR102240329B1 (ko)	2013-06-07	2021-04-14	더 스크립스 리서치 인스티튜트	섬유증의 소분자 억제제
CN107001343B (zh)	2014-12-05	2020-12-11	普尔莫赛德有限公司	抗真菌的化合物
WO2016094570A1 (en) *	2014-12-10	2016-06-16	The California Institute For Biomedical Research	Small molecule inhibitors of fibrosis
WO2016185225A1 (en)	2015-05-21	2016-11-24	Pulmocide Limited	Antifungal 4-(4-(4-(((3r,5r)-5-((1 h -1,2,4-triazol-1 -yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)- 3-methylphenyl)piperazin-1 -yl )-n -(2-h yd roxycyc lo h exyl) b e nzam i d e, or a pharmaceutically acceptable salt thereof.
CN105237392B (zh) *	2015-11-24	2017-12-12	辽宁渤大化工有限公司	芳烷基水杨酸及其衍生物的制备方法
EP3669191A4 (en) *	2017-08-20	2021-04-14	University of Connecticut	NITROGEN-TYPE COMPOUND ANALOGUES AND THEIR METHODS OF USE
WO2021030174A1 (en)	2019-08-09	2021-02-18	University Of Connecticut	Truncated itraconazole analogues and methods of use thereof
GB201917867D0 (en)	2019-12-06	2020-01-22	Pulmocide Ltd	Polymorphs
CN111138421A (zh) *	2019-12-26	2020-05-12	上海英诺富成生物科技有限公司	抗真菌水溶性化合物及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4267179A (en) *	1978-06-23	1981-05-12	Janssen Pharmaceutica, N.V.	Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
DE69330248T2 (de) *	1992-03-18	2002-03-21	Janssen Pharmaceutica N.V., Beerse	Itraconazol- und saperconazolstereoisomere
ZA9410142B (en) *	1993-12-21	1996-05-02	Schering Corp	Tetrahydrofuran antifungals
WO1995019983A1 (en) *	1994-01-24	1995-07-27	Janssen Pharmaceutica N.V.	Watersoluble azole antifungals
FI98688C (fi) *	1994-07-20	1997-07-25	Nokia Telecommunications Oy	Menetelmä lyhytsanomalähetyksen käynnistämiseksi solukkoradiojärjestelmässä, solukkoradiojärjestelmä sekä solukkoradiojärjestelmän tilaajarekisteri
MX9701229A (es) *	1995-06-02	1997-05-31	Schering Corp	Antifungicos de tetrahidrofurano.
WO1997000255A1 (en) *	1995-06-19	1997-01-03	Schering Corporation	Tetrahydrofuran antifungals
HU227744B1 (en) *	1997-02-11	2012-02-28	Janssen Pharmaceutica Nv	Amino acid ester containing azole antifungals, process for their preparation, pharmaceuticals containing the same and intermediates
EP0957101A1 (en) *	1998-05-14	1999-11-17	Janssen Pharmaceutica N.V.	Water soluble azoles as broad-spectrum antifungals

1998
- 1998-05-14 EP EP98201588A patent/EP0957101A1/en not_active Withdrawn
1999
- 1999-05-06 CN CNB998060690A patent/CN1135229C/zh not_active Expired - Fee Related
- 1999-05-06 TR TR2000/03322T patent/TR200003322T2/xx unknown
- 1999-05-06 HR HR20000741A patent/HRP20000741B1/xx not_active IP Right Cessation
- 1999-05-06 PL PL99344037A patent/PL194086B1/pl unknown
- 1999-05-06 AT AT99926304T patent/ATE221884T1/de active
- 1999-05-06 CZ CZ20004108A patent/CZ299481B6/cs not_active IP Right Cessation
- 1999-05-06 DK DK99926304T patent/DK1077976T3/da active
- 1999-05-06 US US09/700,251 patent/US6384030B1/en not_active Expired - Lifetime
- 1999-05-06 TR TR2000/03323T patent/TR200003323T2/xx unknown
- 1999-05-06 ES ES99924942T patent/ES2198915T3/es not_active Expired - Lifetime
- 1999-05-06 HU HU0103536A patent/HUP0103536A3/hu unknown
- 1999-05-06 PL PL99344047A patent/PL194085B1/pl unknown
- 1999-05-06 HR HR20000740A patent/HRP20000740B1/xx not_active IP Right Cessation
- 1999-05-06 BR BR9910448-2A patent/BR9910448A/pt not_active Application Discontinuation
- 1999-05-06 PT PT99926304T patent/PT1077976E/pt unknown
- 1999-05-06 EP EP99926304A patent/EP1077976B1/en not_active Expired - Lifetime
- 1999-05-06 AU AU43615/99A patent/AU758876B2/en not_active Ceased
- 1999-05-06 JP JP2000548333A patent/JP2002514645A/ja active Pending
- 1999-05-06 KR KR1020007011624A patent/KR100575147B1/ko not_active Expired - Fee Related
- 1999-05-06 DE DE69907171T patent/DE69907171T2/de not_active Expired - Lifetime
- 1999-05-06 WO PCT/EP1999/003242 patent/WO1999058529A1/en not_active Ceased
- 1999-05-06 US US09/700,166 patent/US6448244B1/en not_active Expired - Lifetime
- 1999-05-06 WO PCT/EP1999/003243 patent/WO1999058530A1/en not_active Ceased
- 1999-05-06 AT AT99924942T patent/ATE238296T1/de not_active IP Right Cessation
- 1999-05-06 BR BR9911057-1A patent/BR9911057A/pt not_active Application Discontinuation
- 1999-05-06 IL IL13964799A patent/IL139647A0/xx not_active IP Right Cessation
- 1999-05-06 DE DE69902461T patent/DE69902461T2/de not_active Expired - Lifetime
- 1999-05-06 CZ CZ20004109A patent/CZ298702B6/cs not_active IP Right Cessation
- 1999-05-06 IL IL13964999A patent/IL139649A/en not_active IP Right Cessation
- 1999-05-06 NZ NZ507965A patent/NZ507965A/en not_active IP Right Cessation
- 1999-05-06 EP EP99924942A patent/EP1077975B1/en not_active Expired - Lifetime
- 1999-05-06 CA CA002331141A patent/CA2331141C/en not_active Expired - Fee Related
- 1999-05-06 AU AU41417/99A patent/AU751135B2/en not_active Ceased
- 1999-05-06 HU HU0102031A patent/HUP0102031A3/hu unknown
- 1999-05-06 EE EEP200000651A patent/EE04346B1/et not_active IP Right Cessation
- 1999-05-06 CN CNB998059560A patent/CN1137118C/zh not_active Expired - Fee Related
- 1999-05-06 KR KR1020007009640A patent/KR100593395B1/ko not_active Expired - Fee Related
- 1999-05-06 JP JP2000548334A patent/JP2002514646A/ja active Pending
- 1999-05-06 SK SK1681-2000A patent/SK286156B6/sk not_active IP Right Cessation
- 1999-05-06 SI SI9930131T patent/SI1077976T1/xx unknown
- 1999-05-06 SK SK1682-2000A patent/SK285763B6/sk not_active IP Right Cessation
- 1999-05-06 ES ES99926304T patent/ES2182531T3/es not_active Expired - Lifetime
- 1999-05-06 NZ NZ507966A patent/NZ507966A/xx not_active IP Right Cessation
- 1999-05-06 EE EEP200000657A patent/EE04311B1/et not_active IP Right Cessation
- 1999-05-06 CA CA002331187A patent/CA2331187C/en not_active Expired - Fee Related
- 1999-05-10 TW TW088107505A patent/TWI259835B/zh not_active IP Right Cessation
- 1999-05-10 TW TW088107504A patent/TW572899B/zh not_active IP Right Cessation
- 1999-05-11 MY MYPI99001861A patent/MY120248A/en unknown
- 1999-05-11 MY MYPI99001862A patent/MY122147A/en unknown
- 1999-05-13 CO CO99029778A patent/CO5021227A1/es unknown
- 1999-05-13 AR ARP990102276A patent/AR016482A1/es active IP Right Grant
- 1999-05-13 AR ARP990102270A patent/AR016480A1/es active IP Right Grant
2000
- 2000-08-28 BG BG104717A patent/BG64388B1/bg unknown
- 2000-11-09 BG BG104933A patent/BG64954B1/bg unknown
- 2000-11-13 NO NO20005712A patent/NO319851B1/no not_active IP Right Cessation
- 2000-11-13 NO NO20005713A patent/NO319760B1/no not_active IP Right Cessation
- 2000-12-04 ZA ZA200007173A patent/ZA200007173B/en unknown
- 2000-12-13 ZA ZA200007459A patent/ZA200007459B/xx unknown

Also Published As

Publication number	Publication date
ES2182531T3 (es)	2003-03-01
SK16812000A3 (sk)	2001-08-06
EP1077976B1 (en)	2002-08-07
KR20010041480A (ko)	2001-05-25
DE69902461T2 (de)	2003-04-10
JP2002514645A (ja)	2002-05-21
DE69902461D1 (de)	2002-09-12
JP2002514646A (ja)	2002-05-21
IL139649A (en)	2004-09-27
BG104717A (en)	2001-07-31
TWI259835B (en)	2006-08-11
CA2331141C (en)	2008-10-28
CN1300287A (zh)	2001-06-20
TW572899B (en)	2004-01-21
CO5021227A1 (es)	2001-03-27
TR200003323T2 (tr)	2001-02-21
PL194086B1 (pl)	2007-04-30
WO1999058529A1 (en)	1999-11-18
MY120248A (en)	2005-09-30
SK286156B6 (sk)	2008-04-07
EP1077975B1 (en)	2003-04-23
MY122147A (en)	2006-03-31
PT1077976E (pt)	2002-12-31
NO20005713L (no)	2001-01-11
CN1137118C (zh)	2004-02-04
NO20005713D0 (no)	2000-11-13
CA2331187C (en)	2008-11-18
BR9910448A (pt)	2001-01-02
DE69907171D1 (de)	2003-05-28
NZ507965A (en)	2002-05-31
PL344047A1 (en)	2001-09-24
NO319760B1 (no)	2005-09-12
EP1077976A1 (en)	2001-02-28
BR9911057A (pt)	2001-02-06
EP0957101A1 (en)	1999-11-17
IL139647A0 (en)	2002-02-10
DK1077976T3 (da)	2002-12-02
ATE238296T1 (de)	2003-05-15
PL344037A1 (en)	2001-09-24
BG104933A (en)	2001-10-31
HRP20000740B1 (en)	2003-12-31
AR016482A1 (es)	2001-07-04
US6448244B1 (en)	2002-09-10
NZ507966A (en)	2002-10-25
KR20010042852A (ko)	2001-05-25
PL194085B1 (pl)	2007-04-30
HK1032781A1 (en)	2001-08-03
CZ299481B6 (cs)	2008-08-13
HUP0102031A3 (en)	2002-10-28
AU4141799A (en)	1999-11-29
NO20005712D0 (no)	2000-11-13
CN1300288A (zh)	2001-06-20
HRP20000741B1 (hr)	2009-02-28
HRP20000741A2 (en)	2001-06-30
AU758876B2 (en)	2003-04-03
SK16822000A3 (sk)	2001-07-10
NO319851B1 (no)	2005-09-19
SI1077976T1 (en)	2003-02-28
HUP0102031A2 (hu)	2002-05-29
BG64388B1 (bg)	2004-12-30
CN1135229C (zh)	2004-01-21
CA2331187A1 (en)	1999-11-18
DE69907171T2 (de)	2004-02-05
IL139649A0 (en)	2002-02-10
CA2331141A1 (en)	1999-11-18
WO1999058530A1 (en)	1999-11-18
AR016480A1 (es)	2001-07-04
ZA200007173B (en)	2002-03-04
EE04346B1 (et)	2004-08-16
HK1033312A1 (en)	2001-08-24
HRP20000740A2 (en)	2001-10-31
ZA200007459B (en)	2002-09-13
EE200000651A (et)	2002-04-15
ATE221884T1 (de)	2002-08-15
TR200003322T2 (tr)	2001-02-21
NO20005712L (no)	2000-12-07
US6384030B1 (en)	2002-05-07
KR100575147B1 (ko)	2006-05-03
AU751135B2 (en)	2002-08-08
HUP0103536A3 (en)	2002-08-28
ES2198915T3 (es)	2004-02-01
AU4361599A (en)	1999-11-29
KR100593395B1 (ko)	2006-06-28
CZ20004109A3 (en)	2001-05-16
BG64954B1 (bg)	2006-10-31
CZ20004108A3 (en)	2001-05-16
HUP0103536A2 (hu)	2002-07-29
EE04311B1 (et)	2004-06-15
EP1077975A1 (en)	2001-02-28
CZ298702B6 (cs)	2007-12-27
SK285763B6 (sk)	2007-07-06

Legal Events

Date	Code	Title	Description
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20090506

Publication	Publication Date	Title
EE04464B1 (et)	2005-04-15	Indalüülasendatud benseenkarboksamiidid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid
EE200100431A (et)	2002-12-16	16-halogenoepotilooni derivaadid, nende valmistamismeetod ja farmatseutiline kasutamine
EE200200095A (et)	2003-04-15	Sulfonüülkarboksamiidi derivaadid, nende kasutamine, ravim ja nende valmistamismeetod
EE200200487A (et)	2004-02-16	Asetidiini derivaadid, nende valmistamismeetodid ja farmatseutiline kompositsioon
EE200000468A (et)	2002-04-15	Ühendid, nende kasutamine ja farmatseutiline kompositsioon
EE9500064A (et)	1996-06-17	Asendatud 1H-imidasoolid, nende valmistamismeetodid ja farmatseutilised kompositsioonid
EE04275B1 (et)	2004-04-15	Kinoliini derivaadid, nende valmistamismeetodid, kasutamine ja farmatseutilised kompositsioonid
EE04721B1 (et)	2006-10-16	Fenüülksantiini derivaadid, nende valmistamismeetodid ja kasutamine
FI964395L (fi)	1996-10-31	Uudet erytromysiinijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
EE200000225A (et)	2001-06-15	Arüüloksüalküüldialküülamiinid, nende valmistamismeetodid ja farmatseutiline kompositsioon
EE200300245A (et)	2003-08-15	Bensotiofeeni derivaadid, nende valmistamise meetod ja kasutamine
EE04151B1 (et)	2003-10-15	Atsüülpiperasinüülpürimidiinide derivaadid, nendevalmistamine ja kasutamine ravimitena
EE200000657A (et)	2002-04-15	Asoolid, nende valmistamismeetod, kasutamine ravimina ja farmatseutiline kompositsioon
EE200200298A (et)	2003-08-15	Asendatud ftalotsüaniinid ja nende lähteühendid, nende valmistamismeetod ja kasutamine, farmatseutiline kompositsioon ja materjal
EE9800265A (et)	1999-02-15	Erütromütsiini derivaadid, nende valmistamismeetod ja kasutamine ravimitena
EE200000621A (et)	2002-06-17	Pikornaviirusevastased ühendid, nende valmistamine ja kasutamine
HUP9803040A3 (en)	2001-04-28	Thiazole derivatives, process for the preparation thereof, use thereof and pharmaceutical compositions containing them
EE03825B1 (et)	2002-08-15	2-tsüanoiminoimidasooli derivaadid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid
EE9800200A (et)	1998-12-15	Bensoüülguanidiini derivaadid, nende valmistamismeetod, kasutamine ja farmatseutiline kompositsioon
FI953384L (fi)	1996-01-13	Uusi bentsolitiaditsiiniyhdiste, menetelmä sen valmistamiseksi ja sitä sisältävät farmaseuttiset koostumukset
EE03996B1 (et)	2003-04-15	Farmatseutilised kompositsioonid, nende valmistamismeetod ja kasutamine
FI960316L (fi)	1996-03-22	Oksatiolaanit, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
HUP0101234A3 (en)	2002-12-28	Betha-carboline derivatives, process for their preparation and pharmaceutical compositions thereof
EE04260B1 (et)	2004-04-15	Farmatseutiline kompositsioon, selle valmistamisemeetod ja kasutamine
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