EE200200087A - Kompositsioon hepatotsellulaarse kartsinoomi raviks - Google Patents

Kompositsioon hepatotsellulaarse kartsinoomi raviks

Info

Publication number: EE200200087A
Authority: EE; Estonia
Prior art keywords: hepatocellular carcinoma; treatment; composition; docetaxel; mum
Prior art date: 1999-08-31

Application number

EEP200200087A

Other languages

English (en)

Inventor

Chi Chin-Wen

Lin Heng-Liang

Liu Tsung-Yun

Lui Wing-Yiu

Chau Gar-Yang

Original Assignee

Aventis Pharma S.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-31

Filing date

2000-08-29

Publication date

2003-04-15

2000-08-29 Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.

2003-04-15 Publication of EE200200087A publication Critical patent/EE200200087A/et

2009-02-16 Publication of EE05124B1 publication Critical patent/EE05124B1/et

Links

206010073071 hepatocellular carcinoma Diseases 0.000 title abstract 3
231100000844 hepatocellular carcinoma Toxicity 0.000 title abstract 3
ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 2
229960003668 docetaxel Drugs 0.000 abstract 2
229930012538 Paclitaxel Natural products 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229960001592 paclitaxel Drugs 0.000 abstract 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Steroid Compounds (AREA)

EEP200200087A 1999-08-31 2000-08-29 Toimeainena dotsetakseeli v?i selle hdraati sisaldava kompositsiooni kasutamine EE05124B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9920548.6A GB9920548D0 (en)	1999-08-31	1999-08-31	Treatment of hepatocellular carcinoma
PCT/EP2000/008782 WO2001015675A2 (en)	1999-08-31	2000-08-29	Use of docetaxel for treating hepatocellular carcinoma

Publications (2)

Publication Number	Publication Date
EE200200087A true EE200200087A (et)	2003-04-15
EE05124B1 EE05124B1 (et)	2009-02-16

Family

ID=10860081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200200087A EE05124B1 (et)	1999-08-31	2000-08-29	Toimeainena dotsetakseeli v?i selle hdraati sisaldava kompositsiooni kasutamine

Country Status (34)

Country	Link
US (2)	US20030158249A1 (et)
EP (1)	EP1214061B1 (et)
JP (1)	JP4866522B2 (et)
KR (1)	KR100670416B1 (et)
CN (1)	CN1174748C (et)
AT (1)	ATE269700T1 (et)
AU (1)	AU777583B2 (et)
BG (1)	BG65913B1 (et)
BR (1)	BR0013625A (et)
CA (1)	CA2382294C (et)
CZ (1)	CZ301378B6 (et)
DE (1)	DE60011794T2 (et)
DK (1)	DK1214061T3 (et)
EA (1)	EA004804B1 (et)
EE (1)	EE05124B1 (et)
ES (1)	ES2218223T3 (et)
GB (1)	GB9920548D0 (et)
HK (1)	HK1048944B (et)
HR (1)	HRP20020171A2 (et)
HU (1)	HU228861B1 (et)
IL (2)	IL147489A0 (et)
ME (1)	MEP7809A (et)
MX (1)	MXPA02002041A (et)
NO (1)	NO328527B1 (et)
NZ (1)	NZ517604A (et)
PL (1)	PL212612B1 (et)
PT (1)	PT1214061E (et)
RS (1)	RS50148B (et)
SI (1)	SI1214061T1 (et)
SK (1)	SK286378B6 (et)
TW (1)	TW589180B (et)
UA (1)	UA72927C2 (et)
WO (1)	WO2001015675A2 (et)
ZA (1)	ZA200201408B (et)

Families Citing this family (15)

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CN1268619C (zh) *	2003-05-08	2006-08-09	上海迪赛诺化学制药有限公司	多烯紫杉醇三水化合物的制备方法
EP1947094A3 (en) *	2003-12-12	2009-02-18	Quiral Quimica Do Brasil	Process for the preparation of taxane derivatives
US7449196B2 (en) *	2004-07-09	2008-11-11	Robert Sabin	Anti tumor compositions and methods of use
LT3311805T (lt) *	2005-08-31	2020-04-27	Abraxis Bioscience, Llc	Kompozicijos, apimančios silpnai vandenyje tirpius farmacinius agentus ir priešmikrobinius agentus
EP3527202A1 (en)	2005-08-31	2019-08-21	Abraxis BioScience, LLC	Compositions and methods for preparation of poorly water soluble drugs with increased stability
US9839667B2 (en)	2005-10-14	2017-12-12	Allergan, Inc.	Prevention and treatment of ocular side effects with a cyclosporin
US20080081051A1 (en) *	2006-09-28	2008-04-03	Robert Sabin	Method of manufacturing anti-tumor and anti-viral compositions
US20080262078A1 (en) *	2007-04-20	2008-10-23	Namdeo Alok B	Pharmaceutical Compositions
FR2917088B1 (fr) *	2007-06-08	2009-09-04	Aventis Pharma Sa	Dissolution directe du docetaxel dans un solvant dans le polysorbate 80
US8541360B2 (en) *	2008-11-19	2013-09-24	Ben Venue Laboratories, Inc.	Parenteral formulations comprising sugar-based esters and ethers
NZ602382A (en)	2010-03-26	2014-11-28	Abraxis Bioscience Llc	Methods of treatment of hepatocellular carcinoma
US10842770B2 (en) *	2010-05-03	2020-11-24	Teikoku Pharma Usa, Inc.	Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
US8842114B1 (en)	2011-04-29	2014-09-23	Nvidia Corporation	System, method, and computer program product for adjusting a depth of displayed objects within a region of a display
JO3685B1 (ar)	2012-10-01	2020-08-27	Teikoku Pharma Usa Inc	صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CA2976912A1 (en) *	2015-02-17	2016-08-25	Mallinckrodt Llc	Modified docetaxel liposome formulations and uses thereof

Family Cites Families (20)

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FR2601675B1 (fr) *	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US5543154A (en) *	1991-12-27	1996-08-06	Merck & Co., Inc.	Controlled release nifedipine delivery device
JP3254219B2 (ja) *	1993-01-19	2002-02-04	ワーナー−ランバート・コンパニー	安定な経口用のｃｉ−９８１製剤およびその製法
US5801029A (en) *	1993-02-16	1998-09-01	Onyx Pharmaceuticals, Inc.	Cytopathic viruses for therapy and prophylaxis of neoplasia
US5436243A (en) *	1993-11-17	1995-07-25	Research Triangle Institute Duke University	Aminoanthraquinone derivatives to combat multidrug resistance
FR2718963B1 (fr) *	1994-04-25	1996-05-24	Rhone Poulenc Rorer Sa	Nouvelle composition pharmaceutique à base de taxoïdes.
FR2722191B1 (fr) *	1994-07-08	1996-08-23	Rhone Poulenc Rorer Sa	Procede de preparation du trihydrate du (2r,3s)-3-tertbutoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4-acetoxy2alpha-benzoyloxy-5beta,20epoxy-1,7beta,10beta trihydroxy-9-oxo-tax-11-en-13alpha-yle
US5968972A (en)	1995-10-26	1999-10-19	Baker Norton Pharmaceuticals, Inc.	Method for increasing the oral bioactivity of pharmaceutical agents
US6245805B1 (en) *	1995-10-26	2001-06-12	Baker Norton Pharmaceuticals, Inc.	Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
FR2742751B1 (fr) *	1995-12-22	1998-01-30	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
AU741439B2 (en) *	1996-12-30	2001-11-29	Battelle Memorial Institute	Formulation and method for treating neoplasms by inhalation
US6503893B2 (en) *	1996-12-30	2003-01-07	Bone Care International, Inc.	Method of treating hyperproliferative diseases using active vitamin D analogues
PT1023050E (pt) *	1997-06-27	2013-12-04	Abraxis Bioscience Llc	Novas formulações de agentes farmacológicos, métodos para a sua preparação e métodos para a sua utilização
US6544979B1 (en) *	1997-09-18	2003-04-08	Janssen Pharmaceuticals, N.V.	Fused imidazole derivatives for improving oral bioavailability of pharmaceutical agents
EP1027045A4 (en) *	1997-10-31	2004-12-08	Arch Dev Corp	METHODS AND COMPILATIONS FOR REGULATING S-ALPHA REDUCTASE ACTIVITY
UA73092C2 (uk) *	1998-07-17	2005-06-15	Брістол-Майерс Сквібб Компані	Таблетка з ентеросолюбільним покриттям і спосіб її приготування
AU2592600A (en) *	1998-12-23	2000-07-31	G.D. Searle & Co.	Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
GB9909925D0 (en) *	1999-04-29	1999-06-30	Pharmacia & Upjohn Spa	Combined preparations comprising anthracycline derivatives
US8080672B2 (en) *	2005-12-13	2011-12-20	Teva Pharmaceutical Industries Ltd.	Crystal form of atorvastatin hemi-calcium and processes for preparation thereof

1999
- 1999-08-31 GB GBGB9920548.6A patent/GB9920548D0/en not_active Ceased
- 1999-09-22 TW TW088115041A patent/TW589180B/zh not_active IP Right Cessation
2000
- 2000-08-29 JP JP2001519889A patent/JP4866522B2/ja not_active Expired - Fee Related
- 2000-08-29 ES ES00964144T patent/ES2218223T3/es not_active Expired - Lifetime
- 2000-08-29 SI SI200030478T patent/SI1214061T1/xx unknown
- 2000-08-29 EE EEP200200087A patent/EE05124B1/et not_active IP Right Cessation
- 2000-08-29 KR KR1020027002446A patent/KR100670416B1/ko not_active Expired - Fee Related
- 2000-08-29 MX MXPA02002041A patent/MXPA02002041A/es active IP Right Grant
- 2000-08-29 DK DK00964144T patent/DK1214061T3/da active
- 2000-08-29 BR BR0013625-5A patent/BR0013625A/pt not_active Application Discontinuation
- 2000-08-29 WO PCT/EP2000/008782 patent/WO2001015675A2/en not_active Ceased
- 2000-08-29 ME MEP-78/09A patent/MEP7809A/xx unknown
- 2000-08-29 SK SK271-2002A patent/SK286378B6/sk not_active IP Right Cessation
- 2000-08-29 IL IL14748900A patent/IL147489A0/xx active IP Right Grant
- 2000-08-29 AU AU75168/00A patent/AU777583B2/en not_active Ceased
- 2000-08-29 CA CA002382294A patent/CA2382294C/en not_active Expired - Fee Related
- 2000-08-29 HU HU0203197A patent/HU228861B1/hu not_active IP Right Cessation
- 2000-08-29 NZ NZ517604A patent/NZ517604A/en not_active IP Right Cessation
- 2000-08-29 CZ CZ20020739A patent/CZ301378B6/cs not_active IP Right Cessation
- 2000-08-29 EP EP00964144A patent/EP1214061B1/en not_active Expired - Lifetime
- 2000-08-29 HR HR20020171A patent/HRP20020171A2/hr not_active Application Discontinuation
- 2000-08-29 CN CNB008114501A patent/CN1174748C/zh not_active Expired - Fee Related
- 2000-08-29 DE DE60011794T patent/DE60011794T2/de not_active Expired - Lifetime
- 2000-08-29 AT AT00964144T patent/ATE269700T1/de active
- 2000-08-29 RS YUP-114/02A patent/RS50148B/sr unknown
- 2000-08-29 UA UA2002021546A patent/UA72927C2/uk unknown
- 2000-08-29 HK HK03101197.6A patent/HK1048944B/zh not_active IP Right Cessation
- 2000-08-29 EA EA200200313A patent/EA004804B1/ru not_active IP Right Cessation
- 2000-08-29 PT PT00964144T patent/PT1214061E/pt unknown
- 2000-08-29 PL PL353198A patent/PL212612B1/pl unknown
2002
- 2002-01-06 IL IL147489A patent/IL147489A/en not_active IP Right Cessation
- 2002-02-19 ZA ZA200201408A patent/ZA200201408B/xx unknown
- 2002-02-20 NO NO20020829A patent/NO328527B1/no not_active IP Right Cessation
- 2002-02-27 US US10/083,565 patent/US20030158249A1/en not_active Abandoned
- 2002-02-28 BG BG106460A patent/BG65913B1/bg unknown
2007
- 2007-06-12 US US11/761,512 patent/US20080045584A1/en not_active Abandoned

Also Published As

Publication number	Publication date
BG106460A (bg)	2002-09-30
JP2003508427A (ja)	2003-03-04
HK1048944B (zh)	2005-04-22
US20030158249A1 (en)	2003-08-21
NO20020829L (no)	2002-02-20
BG65913B1 (bg)	2010-05-31
ZA200201408B (en)	2003-07-30
PL212612B1 (pl)	2012-10-31
TW589180B (en)	2004-06-01
US20080045584A1 (en)	2008-02-21
RS50148B (sr)	2009-05-06
ME00624B (me)	2011-12-20
DE60011794D1 (de)	2004-07-29
MEP7809A (en)	2011-12-20
YU11402A (sh)	2005-07-19
DE60011794T2 (de)	2005-07-14
HUP0203197A2 (hu)	2003-01-28
ES2218223T3 (es)	2004-11-16
CZ301378B6 (cs)	2010-02-03
CZ2002739A3 (cs)	2002-06-12
EA004804B1 (ru)	2004-08-26
JP4866522B2 (ja)	2012-02-01
BR0013625A (pt)	2002-05-14
MXPA02002041A (es)	2002-08-20
CN1372466A (zh)	2002-10-02
SI1214061T1 (en)	2004-12-31
HU228861B1 (hu)	2013-06-28
SK286378B6 (sk)	2008-08-05
HK1048944A1 (en)	2003-04-25
ATE269700T1 (de)	2004-07-15
AU7516800A (en)	2001-03-26
NZ517604A (en)	2004-04-30
HRP20020171A2 (en)	2004-02-29
NO328527B1 (no)	2010-03-08
IL147489A0 (en)	2002-08-14
CA2382294A1 (en)	2001-03-08
UA72927C2 (uk)	2005-05-16
SK2712002A3 (en)	2002-07-02
EE05124B1 (et)	2009-02-16
EP1214061B1 (en)	2004-06-23
KR20020060166A (ko)	2002-07-16
EA200200313A1 (ru)	2002-08-29
PT1214061E (pt)	2004-09-30
CA2382294C (en)	2008-06-03
IL147489A (en)	2006-06-11
HUP0203197A3 (en)	2005-01-28
DK1214061T3 (da)	2004-11-01
EP1214061A2 (en)	2002-06-19
GB9920548D0 (en)	1999-11-03
WO2001015675A2 (en)	2001-03-08
KR100670416B1 (ko)	2007-01-17
CN1174748C (zh)	2004-11-10
PL353198A1 (en)	2003-11-03
WO2001015675A3 (en)	2001-09-20
NO20020829D0 (no)	2002-02-20
AU777583B2 (en)	2004-10-21

Legal Events

Date	Code	Title	Description
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2016-04-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20150829

Publication	Publication Date	Title
EE200200087A (et)	2003-04-15	Kompositsioon hepatotsellulaarse kartsinoomi raviks
MY147643A (en)	2012-12-31	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of mania and bipolar disorder
HUP0301405A2 (hu)	2003-08-28	Fokozott oldékonyságú gyógyhatású komponenseket tartalmazó készítmények
NO20034204D0 (no)	2003-09-22	Farmasöytiske kombinasjoner til behandling av kreft
MXPA05012323A (es)	2006-01-30	Sulfonamidas ciclicas para la inhibicion de gama-secretasa.
GB0223038D0 (en)	2002-11-13	Therapeutic compounds
NO20042596L (no)	2004-06-21	Inbibitorer av 11-beta-hydroksy steroid dehydrogenase type 1
ATE468332T1 (de)	2010-06-15	Phenyl-(4-(3-phenyl-1h-pyrazol-4-yl)-pyrimidin- - yi)aminderivate
HRP20040059B1 (hr)	2008-05-31	Tretman infekcije nokta s no
ATE408601T1 (de)	2008-10-15	Fredericamycin-derivate
DE60336664D1 (de)	2011-05-19	Nichtnukleosidische reverse-transkriptase-hemmer
SE9903759D0 (sv)	1999-10-18	Pharmaceutically active compounds
ATE478662T1 (de)	2010-09-15	Arzneilösungen enthaltend modafinilverbindungen
MY148459A (en)	2013-04-30	Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression
CY1106319T1 (el)	2011-10-12	Τοπικη θepαπεια στη μασταλγια
DE60128100D1 (de)	2007-06-06	Analgetisches arzneimittel
NO20032597L (no)	2003-06-06	Anvendelse av SARP-1 for behandlingen og/eller forebyggingen av skleroderma
EA200700979A1 (ru)	2007-10-26	Пероральные твердые лекарственные формы, содержащие низкую дозу эстрадиола
ATE306940T1 (de)	2005-11-15	Zusammensetzung gegen coccidiose
AU2016219620A1 (en)	2016-09-15	Compositions and methods useful for treatment of respiratory illness
UA95094C2 (ru)	2011-07-11	Применение бензоконденсированных гетероциклических сульфамидных производных для лечения маниакального синдрома и биполярного расстройства
TW200505836A (en)	2005-02-16	Cyclic sulfonamides for inhibition of gamma-secretase