EE200300398A - Isoksasoliini derivaat, selle saamine ja kasutamine depresioonivastase ravimi valmistamiseks ning seda sisaldav ravimkompositsioon - Google Patents

Isoksasoliini derivaat, selle saamine ja kasutamine depresioonivastase ravimi valmistamiseks ning seda sisaldav ravimkompositsioon

Info

Publication number
EE200300398A
EE200300398A EEP200300398A EEP200300398A EE200300398A EE 200300398 A EE200300398 A EE 200300398A EE P200300398 A EEP200300398 A EE P200300398A EE P200300398 A EEP200300398 A EE P200300398A EE 200300398 A EE200300398 A EE 200300398A
Authority
EE
Estonia
Prior art keywords
preparation
pharmaceutical composition
composition containing
isoxazoline derivative
medicament
Prior art date
Application number
EEP200300398A
Other languages
English (en)
Estonian (et)
Inventor
Ignacio Andr�s-Gil Jos�
Javier Fernndez-Gadea Francisco
Jes�s Alc�zar-Vaca Manuel
Maria Cid-Nu�ez Jos�
Pastor-Fernandez Joaquin
Adrianus Hendrikus Petrus Megens Antonius
Irma Christine Maria Heylen Godelieve
Jean Michel Langlois Xavier
Henrica Maria Bakker Margaretha
Horst Wolfgang Steckler Thomas
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE200300398A publication Critical patent/EE200300398A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EEP200300398A 2001-02-21 2002-02-13 Isoksasoliini derivaat, selle saamine ja kasutamine depresioonivastase ravimi valmistamiseks ning seda sisaldav ravimkompositsioon EE200300398A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01200611 2001-02-21
EP01201264 2001-04-05
PCT/EP2002/001567 WO2002066484A1 (fr) 2001-02-21 2002-02-13 Derives d'isoxazolines comme antidepresseurs

Publications (1)

Publication Number Publication Date
EE200300398A true EE200300398A (et) 2003-12-15

Family

ID=26076836

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300398A EE200300398A (et) 2001-02-21 2002-02-13 Isoksasoliini derivaat, selle saamine ja kasutamine depresioonivastase ravimi valmistamiseks ning seda sisaldav ravimkompositsioon

Country Status (32)

Country Link
US (1) US7169786B2 (fr)
EP (1) EP1368358B1 (fr)
JP (1) JP3953424B2 (fr)
KR (1) KR100848898B1 (fr)
CN (1) CN100400540C (fr)
AR (1) AR035685A1 (fr)
AT (1) ATE337322T1 (fr)
AU (1) AU2002244717B2 (fr)
BG (1) BG107984A (fr)
BR (1) BR0207433A (fr)
CA (1) CA2437505C (fr)
CY (1) CY1106448T1 (fr)
CZ (1) CZ20032515A3 (fr)
DE (1) DE60214138T2 (fr)
DK (1) DK1368358T3 (fr)
EA (1) EA006747B1 (fr)
EE (1) EE200300398A (fr)
EG (1) EG23929A (fr)
ES (1) ES2271230T3 (fr)
HR (1) HRP20030647A2 (fr)
HU (1) HUP0303270A3 (fr)
IL (2) IL157470A0 (fr)
MX (1) MXPA03007432A (fr)
MY (1) MY137836A (fr)
NO (1) NO20033700L (fr)
NZ (1) NZ526741A (fr)
PL (1) PL208593B1 (fr)
PT (1) PT1368358E (fr)
SI (1) SI1368358T1 (fr)
SK (1) SK11612003A3 (fr)
TW (1) TWI257392B (fr)
WO (1) WO2002066484A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203299D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel compounds
ATE372342T1 (de) * 2002-04-02 2007-09-15 Janssen Pharmaceutica Nv Substituierte aminoisoxazolinderivate und ihre verwendung als antidepressiva
TW200409777A (en) * 2002-08-12 2004-06-16 Janssen Pharmaceutica Nv C-substituted tricyclic isoxazoline derivatives and their use as anti-depressants
CN100522972C (zh) * 2002-08-15 2009-08-05 詹森药业有限公司 稠合杂环异噁唑啉衍生物和它们作为抗抑郁剂的用途
JP4478570B2 (ja) * 2002-08-21 2010-06-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｃ６−およびｃ９−置換’４，３−ｃ！イソキサゾリン誘導体およびそれらの抗鬱薬としての使用
CA2517081A1 (fr) * 2003-03-07 2004-09-16 Astellas Pharma Inc. Derive heterocyclique azote contenant du styryl 2,6-disubstitue
EP1944306A1 (fr) * 2003-09-17 2008-07-16 Janssen Pharmaceutica, N.V. Composés hétérocycliques fusionnés
SI1668014T1 (sl) * 2003-09-17 2009-06-30 Janssen Pharmaceutica Nv Kondenzirane heterociklične spojine kot modulatorji serotoninskih receptorjev
ES2331144T3 (es) * 2004-11-26 2009-12-22 Janssen Pharmaceutica Nv Derivados de isoxazolina-indol con actividad antipsicotica y ansiolitica mejorada.
NZ579431A (en) 2007-03-09 2012-04-27 Sanofi Aventis Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
WO2008154442A1 (fr) * 2007-06-08 2008-12-18 Helicon Therapeutics, Inc. Dérivés d'urée de pyrazoloquinoline thérapeutiques
WO2009082268A2 (fr) 2007-12-21 2009-07-02 Alla Chem, Llc Ligands dalpha-adrénorécepteurs, de récepteurs de dopamine, de l'histamine, d'imidazoline et de sérotonine ainsi que leurs procédés d'utilisation
AR078171A1 (es) 2009-09-15 2011-10-19 Sanofi Aventis Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2055011T3 (es) * 1988-09-19 1994-08-16 Akzo Nv Un procedimiento para la preparacion de derivados de tetrahidronaftaleno e indano.
US5880121A (en) * 1996-01-05 1999-03-09 Hoechst Marion Roussel Inc. 4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
EP0892804B1 (fr) * 1996-04-12 2002-08-28 Janssen Pharmaceutica N.V. Derives isoxazolidines
HUP9602763A3 (en) * 1996-10-09 1999-05-28 Egyt Gyogyszervegyeszeti Gyar 3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
JP2002527438A (ja) * 1998-10-09 2002-08-27 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ４，５−ジヒドロ−イソオキサゾール誘導体及びそれらの製薬学的使用

Also Published As

Publication number Publication date
CA2437505C (fr) 2010-02-09
CY1106448T1 (el) 2011-10-12
HUP0303270A2 (hu) 2004-01-28
HK1065537A1 (zh) 2005-02-25
ATE337322T1 (de) 2006-09-15
US7169786B2 (en) 2007-01-30
HRP20030647A2 (en) 2005-06-30
US20040122037A1 (en) 2004-06-24
MXPA03007432A (es) 2003-11-18
JP2004518748A (ja) 2004-06-24
NO20033700L (no) 2003-10-21
EP1368358A1 (fr) 2003-12-10
BR0207433A (pt) 2004-06-01
AU2002244717B2 (en) 2007-07-19
PT1368358E (pt) 2007-01-31
EA200300915A1 (ru) 2004-06-24
PL208593B1 (pl) 2011-05-31
DE60214138D1 (de) 2006-10-05
IL157470A (en) 2008-07-08
PL363264A1 (en) 2004-11-15
KR20030076590A (ko) 2003-09-26
SK11612003A3 (sk) 2004-04-06
CZ20032515A3 (cs) 2003-12-17
EG23929A (en) 2008-01-14
KR100848898B1 (ko) 2008-07-29
IL157470A0 (en) 2004-03-28
NO20033700D0 (no) 2003-08-20
EA006747B1 (ru) 2006-04-28
JP3953424B2 (ja) 2007-08-08
DE60214138T2 (de) 2007-03-29
DK1368358T3 (da) 2007-01-02
WO2002066484A1 (fr) 2002-08-29
HUP0303270A3 (en) 2007-03-28
EP1368358B1 (fr) 2006-08-23
BG107984A (bg) 2004-09-30
SI1368358T1 (sl) 2007-02-28
TWI257392B (en) 2006-07-01
AR035685A1 (es) 2004-06-23
CA2437505A1 (fr) 2002-08-29
ES2271230T3 (es) 2007-04-16
CN100400540C (zh) 2008-07-09
MY137836A (en) 2009-03-31
CN1492871A (zh) 2004-04-28
NZ526741A (en) 2004-04-30

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