EE9800109A - 5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks - Google Patents

5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks

Info

Publication number: EE9800109A
Authority: EE; Estonia
Prior art keywords: preparation; methylerythronolide; desosaminyl; new derivatives; bioactive products
Prior art date: 1995-10-09

Application number

EE9800109A

Other languages

English (en)

Other versions

EE03878B1 (et

Inventor

Bonnet Alain

Chappert Bernadette

Lagouardat Jacques

Original Assignee

Hoechst Marion Roussel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-09

Filing date

1996-10-08

Publication date

1998-10-15

1996-10-08 Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel

1998-10-15 Publication of EE9800109A publication Critical patent/EE9800109A/et

2002-10-15 Publication of EE03878B1 publication Critical patent/EE03878B1/et

Links

238000002360 preparation method Methods 0.000 title 2
QTLYNHBYTKOXTE-HLJDHPTISA-N [H][C@@]1(O[C@@H]2[C@@H](C)[C@H](O)[C@@H](C)C(=O)OC(CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)OC)O[C@H](C)C[C@@H]([C@H]1O)N(C)C Chemical class [H][C@@]1(O[C@@H]2[C@@H](C)[C@H](O)[C@@H](C)C(=O)OC(CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)OC)O[C@H](C)C[C@@H]([C@H]1O)N(C)C QTLYNHBYTKOXTE-HLJDHPTISA-N 0.000 title 1
230000000975 bioactive effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EE9800109A 1995-10-09 1996-10-08 5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks EE03878B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9511861A FR2739620B1 (fr)	1995-10-09	1995-10-09	Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
PCT/FR1996/001567 WO1997013774A2 (fr)	1995-10-09	1996-10-08	Nouveaux derives de la 5-o-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs

Publications (2)

Publication Number	Publication Date
EE9800109A true EE9800109A (et)	1998-10-15
EE03878B1 EE03878B1 (et)	2002-10-15

Family

ID=9483377

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9800109A EE03878B1 (et)	1995-10-09	1996-10-08	5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks

Country Status (33)

Country	Link
US (1)	US6011142A (et)
EP (1)	EP0854879B1 (et)
JP (1)	JP4327248B2 (et)
KR (1)	KR100451063B1 (et)
CN (1)	CN1067401C (et)
AP (1)	AP888A (et)
AR (1)	AR004688A1 (et)
AT (1)	ATE212034T1 (et)
AU (1)	AU708351B2 (et)
BG (1)	BG63752B1 (et)
BR (1)	BR9610959A (et)
CA (1)	CA2231562C (et)
CZ (1)	CZ293430B6 (et)
DE (1)	DE69618607T2 (et)
DK (1)	DK0854879T3 (et)
EA (1)	EA000765B1 (et)
EE (1)	EE03878B1 (et)
ES (1)	ES2171722T3 (et)
FR (1)	FR2739620B1 (et)
GE (1)	GEP20032899B (et)
HU (1)	HUP9900136A3 (et)
IL (1)	IL123613A0 (et)
MX (1)	MX9802655A (et)
NO (1)	NO312592B1 (et)
PL (1)	PL183645B1 (et)
PT (1)	PT854879E (et)
RO (1)	RO118874B1 (et)
SI (1)	SI0854879T1 (et)
SK (1)	SK283619B6 (et)
TR (1)	TR199800624T1 (et)
UA (1)	UA52621C2 (et)
WO (1)	WO1997013774A2 (et)
ZA (1)	ZA966666B (et)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2777282B1 (fr) *	1998-04-08	2001-04-20	Hoechst Marion Roussel Inc	Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
US6399582B1 (en)	1999-04-16	2002-06-04	Ortho-Mcneil Pharmaceutical, Inc.	Ketolide antibacterials
US6590083B1 (en)	1999-04-16	2003-07-08	Ortho-Mcneil Pharmaceutical, Inc.	Ketolide antibacterials
AU775637B2 (en) *	1999-04-16	2004-08-12	Kosan Biosciences, Inc.	Macrolide antiinfective agents
GB0031312D0 (en) *	2000-12-21	2001-02-07	Glaxo Group Ltd	Macrolides
US7601695B2 (en) *	2003-03-10	2009-10-13	Optimer Pharmaceuticals, Inc.	Antibacterial agents
AU2008316830B2 (en)	2007-10-25	2016-03-17	Cempra Pharmaceuticals, Inc.	Process for the preparation of macrolide antibacterial agents
CN107854477A (zh)	2008-10-24	2018-03-30	森普拉制药公司	使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
US9480679B2 (en)	2009-09-10	2016-11-01	Cempra Pharmaceuticals, Inc.	Methods for treating malaria, tuberculosis and MAC diseases
HRP20160168T1 (hr)	2010-03-22	2016-03-25	Cempra Pharmaceuticals Inc	Kristalne forme makrolida i njihova uporaba
BR112012029586A2 (pt)	2010-05-20	2016-08-02	Cempra Pharmaceuticals Inc	processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20130120458A (ko)	2010-09-10	2013-11-04	셈프라 파마슈티컬스, 인크.	질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en)	2012-03-27	2013-10-03	Cempra Pharmaceuticals, Inc.	Parenteral formulations for administering macrolide antibiotics
WO2014152326A1 (en)	2013-03-14	2014-09-25	Cempra Pharmaceuticals, Inc.	Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en)	2013-03-15	2018-08-09	Cempra Pharmaceuticals, Inc.	Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3923784A (en) *	1973-09-10	1975-12-02	Hoffmann La Roche	Erythromycin a derivatives
US4518590A (en) *	1984-04-13	1985-05-21	Pfizer Inc.	9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4742049A (en) *	1986-06-04	1988-05-03	Abbott Laboratories	Semisynthetic erythromycin antibiotics
AU1204288A (en) *	1987-02-24	1988-08-25	Beecham Group Plc	Erythromycins
US5523399A (en) *	1991-12-27	1996-06-04	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide derivatives
ES2087737T3 (es) *	1992-04-22	1996-07-16	Taisho Pharmaceutical Co Ltd	Un derivado 5-o-desosaminil-eritronoluro a.
FR2692579B1 (fr) *	1992-06-19	1995-06-02	Roussel Uclaf	Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
AU671899B2 (en) *	1993-01-26	1996-09-12	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide derivative

1995
- 1995-10-09 FR FR9511861A patent/FR2739620B1/fr not_active Expired - Fee Related
1996
- 1996-08-06 ZA ZA9606666A patent/ZA966666B/xx unknown
- 1996-08-10 UA UA98041836A patent/UA52621C2/uk unknown
- 1996-10-07 AR ARP960104634A patent/AR004688A1/es not_active Application Discontinuation
- 1996-10-08 KR KR10-1998-0702581A patent/KR100451063B1/ko not_active Expired - Lifetime
- 1996-10-08 JP JP51476697A patent/JP4327248B2/ja not_active Expired - Lifetime
- 1996-10-08 HU HU9900136A patent/HUP9900136A3/hu unknown
- 1996-10-08 EE EE9800109A patent/EE03878B1/et not_active IP Right Cessation
- 1996-10-08 SK SK431-98A patent/SK283619B6/sk unknown
- 1996-10-08 DK DK96933501T patent/DK0854879T3/da active
- 1996-10-08 US US09/051,378 patent/US6011142A/en not_active Ceased
- 1996-10-08 AT AT96933501T patent/ATE212034T1/de active
- 1996-10-08 EA EA199800280A patent/EA000765B1/ru not_active IP Right Cessation
- 1996-10-08 ES ES96933501T patent/ES2171722T3/es not_active Expired - Lifetime
- 1996-10-08 EP EP96933501A patent/EP0854879B1/fr not_active Expired - Lifetime
- 1996-10-08 CA CA002231562A patent/CA2231562C/fr not_active Expired - Lifetime
- 1996-10-08 AP APAP/P/1998/001216A patent/AP888A/en active
- 1996-10-08 BR BR9610959A patent/BR9610959A/pt not_active Application Discontinuation
- 1996-10-08 PL PL96326001A patent/PL183645B1/pl not_active IP Right Cessation
- 1996-10-08 CZ CZ19981055A patent/CZ293430B6/cs not_active IP Right Cessation
- 1996-10-08 IL IL12361396A patent/IL123613A0/xx not_active IP Right Cessation
- 1996-10-08 GE GEAP19964227A patent/GEP20032899B/en unknown
- 1996-10-08 AU AU72208/96A patent/AU708351B2/en not_active Expired
- 1996-10-08 DE DE69618607T patent/DE69618607T2/de not_active Expired - Lifetime
- 1996-10-08 SI SI9630452T patent/SI0854879T1/xx unknown
- 1996-10-08 TR TR1998/00624T patent/TR199800624T1/xx unknown
- 1996-10-08 RO RO98-00826A patent/RO118874B1/ro unknown
- 1996-10-08 WO PCT/FR1996/001567 patent/WO1997013774A2/fr not_active Ceased
- 1996-10-08 CN CN96197514A patent/CN1067401C/zh not_active Expired - Lifetime
- 1996-10-08 PT PT96933501T patent/PT854879E/pt unknown
1998
- 1998-03-25 BG BG102350A patent/BG63752B1/bg unknown
- 1998-04-03 MX MX9802655A patent/MX9802655A/es unknown
- 1998-04-08 NO NO19981630A patent/NO312592B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL123613A0 (en)	1998-10-30
TR199800624T1 (xx)	1998-06-22
FR2739620A1 (fr)	1997-04-11
EP0854879A2 (fr)	1998-07-29
NO981630D0 (no)	1998-04-08
JP4327248B2 (ja)	2009-09-09
BR9610959A (pt)	1999-03-02
MX9802655A (es)	1998-11-30
AU7220896A (en)	1997-04-30
EA199800280A1 (ru)	1998-10-29
AP888A (en)	2000-11-10
ES2171722T3 (es)	2002-09-16
SI0854879T1 (en)	2002-08-31
KR19990064100A (ko)	1999-07-26
FR2739620B1 (fr)	1997-12-19
BG63752B1 (bg)	2002-11-29
CA2231562C (fr)	2006-11-28
HUP9900136A3 (en)	2000-04-28
ZA966666B (en)	1997-08-06
CA2231562A1 (fr)	1997-04-17
JPH11513401A (ja)	1999-11-16
SK43198A3 (en)	1998-11-04
PT854879E (pt)	2002-07-31
DE69618607D1 (de)	2002-02-21
CZ293430B6 (cs)	2004-04-14
US6011142A (en)	2000-01-04
CN1199403A (zh)	1998-11-18
EP0854879B1 (fr)	2002-01-16
HUP9900136A1 (hu)	1999-05-28
SK283619B6 (sk)	2003-10-07
DE69618607T2 (de)	2002-08-14
ATE212034T1 (de)	2002-02-15
NO312592B1 (no)	2002-06-03
AR004688A1 (es)	1999-03-10
WO1997013774A2 (fr)	1997-04-17
RO118874B1 (ro)	2003-12-30
PL183645B1 (pl)	2002-06-28
EA000765B1 (ru)	2000-04-24
BG102350A (en)	1999-03-31
PL326001A1 (en)	1998-08-17
CN1067401C (zh)	2001-06-20
KR100451063B1 (ko)	2004-12-17
NO981630L (no)	1998-04-08
UA52621C2 (uk)	2003-01-15
CZ105598A3 (cs)	1998-07-15
GEP20032899B (en)	2003-02-25
EE03878B1 (et)	2002-10-15
WO1997013774A3 (fr)	1997-05-29
DK0854879T3 (da)	2002-05-06
AU708351B2 (en)	1999-08-05

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2004-12-15	GB1A	Change in the ownership or in the address of the owner
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2007-06-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20061008

Publication	Publication Date	Title
EE9800065A (et)	1998-08-17	5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks
EE03482B1 (et)	2001-08-15	Kinasoliiniderivaadid, nende valmistamismeetod ja kasutamine
FI924054A7 (fi)	1993-03-15	Imidatsoliin liitetyt iso- ja heterosyklit, menetelmä niiden valmistamiseksi ja niiden käyttö
FI945900A7 (fi)	1995-06-18	Bentseenisulfonamidijohdokset ja menetelmä näiden valmistamiseksi
FI941137L (fi)	1994-09-12	2-debentsoyyli-2-asyylitaksolijohdannaisia ja menetelmiä niiden valmistamiseksi
FI964028L (fi)	1996-10-08	Uusi farmaseuttinen formulaatio ja menetelmä
EE03231B1 (et)	1999-10-15	Tetratsüklilised derivaadid, nende valmistamismeetod ja kasutamine
EE9600172A (et)	1997-06-16	Puriin-6-ooni derivaadid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja ravimid
FI944279L (fi)	1994-09-15	Suolatuote ja menetelmä sen valmistamiseksi
FI956080L (fi)	1996-01-17	Kuidutettu selluloosatuote ja menetelmä sen valmistamiseksi
FI931336A7 (fi)	1993-09-29	Polyhydroksimetyleenijohdannaisia sisältäviä lääkkeitä, menetelmä niiden valmistamiseksi ja käyttämiseksi
FI953898A0 (fi)	1995-08-18	Glysiiniamidijohdannaisia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä lääkeaineita
FI935465L (fi)	1994-06-08	Termoplastinen koostumus, menetelmä sen valmistamiseksi ja sen käyttö
FI953919A7 (fi)	1995-08-21	Pyrrolydeenimetyylijohdannaiset ja menetelmä niiden valmistamiseksi
EE9800302A (et)	1999-02-15	Arüülglütsiinamiidi derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline preparaat
FI942499L (fi)	1994-07-27	Indolijohdannainen, menetelmä sen valmistamiseksi ja sen lääkekäyttö
EE03878B1 (et)	2002-10-15	5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks
FI944713L (fi)	1994-12-02	4-difenyylimetyylipiperidiinijohdannaisia ja menetelmä niiden valmistamiseksi
EE9800145A (et)	1998-10-15	Fenüülamidiini derivaadid, meetodid nende valmistamiseks ja nende kasutamine arstimitena
FI903589A7 (fi)	1991-01-18	Lääkkeitä, jotka pohjautuvat 4,1,2-1H-bentsoksadiatsiinin johdannaisiin, uusia johdannaisia ja menetelmiä niiden valmistamiseksi
FI951631L (fi)	1995-04-05	Substituoituja kynureniinejä, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
FI955076A7 (fi)	1996-04-27	Elintarviketuote ja menetelmä sen valmistamiseksi
FI972988L (fi)	1997-09-11	Menetelmiä ja farmaseuttisia koostumuksia, joissa käytetään desmetyyliselegiliiniä
FI931346A7 (fi)	1993-09-27	Butadieenijohdokset ja menetelmä niiden valmistamiseksi
FI973434L (fi)	1997-08-21	Aminotetralonijohdannaisia ja menetelmä niiden valmistamiseksi