EE9800248A - Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine - Google Patents

Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine

Info

Publication number
EE9800248A
EE9800248A EE9800248A EE9800248A EE9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A EE 9800248 A EE9800248 A EE 9800248A
Authority
EE
Estonia
Prior art keywords
freeze
preparation
ultrasound contrast
contrast medium
dried
Prior art date
Application number
EE9800248A
Other languages
English (en)
Estonian (et)
Inventor
Helge Gulliksen Per
Undheim Br�nden Jorunn
Kjersti Fahlvik Anne
Swaerd-Nordmo Marit
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603466.5A external-priority patent/GB9603466D0/en
Priority claimed from GBGB9611894.8A external-priority patent/GB9611894D0/en
Priority claimed from GBGB9624919.8A external-priority patent/GB9624919D0/en
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of EE9800248A publication Critical patent/EE9800248A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Light Receiving Elements (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
EE9800248A 1996-02-19 1997-02-19 Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine EE9800248A (et)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9603466.5A GB9603466D0 (en) 1996-02-19 1996-02-19 Improvements in or relating to contrast agents
GBGB9611894.8A GB9611894D0 (en) 1996-06-07 1996-06-07 Improvements in or relating to contrast agents
GBGB9624919.8A GB9624919D0 (en) 1996-11-29 1996-11-29 Product
PCT/GB1997/000458 WO1997029782A1 (en) 1996-02-19 1997-02-19 Thermally stabilized contrast agent

Publications (1)

Publication Number Publication Date
EE9800248A true EE9800248A (et) 1999-02-15

Family

ID=27268136

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800248A EE9800248A (et) 1996-02-19 1997-02-19 Külmkuivatatud, vesiikuleid sisaldav ultraheli kontrastaine, selle valmistamismeetod ning ladustamise ja transpordi meetod, ultraheli kontrastaine keskkond ja selle valmistamismeetod ning külmkuivatuse stabilisaatorite kasutamine

Country Status (18)

Country Link
EP (1) EP0885016B1 (de)
JP (1) JP4250747B2 (de)
KR (1) KR100501863B1 (de)
CN (1) CN1092988C (de)
AT (1) ATE237362T1 (de)
AU (1) AU722735B2 (de)
CA (1) CA2246778A1 (de)
CZ (1) CZ262698A3 (de)
DE (1) DE69720979T2 (de)
EA (1) EA000900B1 (de)
EE (1) EE9800248A (de)
ES (1) ES2197331T3 (de)
HU (1) HUP9900812A3 (de)
IL (1) IL125800A0 (de)
NO (1) NO313815B1 (de)
NZ (1) NZ331372A (de)
PL (1) PL328309A1 (de)
WO (1) WO1997029782A1 (de)

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EP1590006B1 (de) 2003-02-04 2010-09-08 Bracco Suisse SA Ultraschall kontrastmittel und verfahren zur erstellung
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WO2006018433A1 (en) 2004-08-18 2006-02-23 Bracco Research Sa Gas-filled microvesicles composition for contrast imaging
WO2006076826A1 (fr) * 2005-01-18 2006-07-27 Institute Of Pharmacology Toxicology, Academy Of Military Medical Sciences Composition de contraste pour ultrasons utilisant un phospholipide filmogene et procede de preparation de celle-ci
AU2007293888B2 (en) 2006-09-05 2013-05-02 Bracco Suisse S.A. Gas-filled microvesicles with polymer-modified lipids
EP2117603A2 (de) 2006-12-19 2009-11-18 Bracco International B.V. Targeting und therapeutische verbindungen und gasgefüllte mikrovesikel mit diesen verbindungen
KR20100057063A (ko) 2007-09-11 2010-05-28 몬도바이오테크 래보래토리즈 아게 치료제로서의 펩티드의 용도
WO2009033714A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
KR20100058555A (ko) 2007-09-11 2010-06-03 몬도바이오테크 래보래토리즈 아게 치료제로서의 ｂｐｐ－ｂ의 용도
AU2008303893A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of adrenomedullin as a therapeutic agent for the treatment of excessive angiogenesis
US20100204131A1 (en) 2007-09-11 2010-08-12 Dorian Bevec Use of a peptide as a therapeutic agent
AU2008303928A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of NF-KAPPAB inhibitor SN50 and optionally angiotensin III as therapeutic agents in the treatment of EG HBV infection
US20100204107A1 (en) 2007-09-11 2010-08-12 Dorian Bevec Use of urodilatin as a therapeutic agent
WO2009043468A2 (en) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of corticotropin-releasing factor as a therapeutic agent
AU2008306190A1 (en) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of bubuc and optionally EAA-MART1 (26-35) as a therapeutic agent for the treatment of HCMV infections
KR20100061481A (ko) 2007-09-11 2010-06-07 몬도바이오테크 래보래토리즈 아게 치료제로서의 미니가스트린
WO2009033667A2 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of a peptide as a therapeutic agent
KR20100059863A (ko) 2007-09-11 2010-06-04 몬도바이오테크 래보래토리즈 아게 치료제로서의 펩티드 티모신 베타 ４ 단독 또는 세크로핀 ａ와의 배합물의 용도
EP2090322A1 (de) 2008-02-18 2009-08-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Verwendung von FSH-Rezeptorliganden zur Diagnose und Behandlung von Krebs
EP2346532B1 (de) 2008-10-07 2020-10-07 Bracco Suisse SA Target-konstrukt mit einem anti-polymer-antikörper und an diesen bindende mikrovesikel
CN101649293B (zh) * 2009-09-02 2012-07-18 中国农业大学 一种微生物冷冻干燥保护剂及其应用
ES2673277T3 (es) 2010-08-09 2018-06-21 Bracco Suisse Sa Microvesículas dirigidas llenas de gas
EP2426202A1 (de) 2010-09-03 2012-03-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kinasen als Targets für antidiabetische Therapien
CN103269717B (zh) 2010-12-24 2016-08-03 博莱科瑞士股份有限公司 气体填充微囊泡用作疫苗
WO2013028942A1 (en) 2011-08-24 2013-02-28 The Regents Of The University Of California Targeting microbubbles
PT2768484T (pt) 2011-10-21 2019-10-28 Jazz Pharmaceuticals Res Llc Lipossomas liofilizados
EP2589383A1 (de) 2011-11-06 2013-05-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin FKBP-subtypspezifisches Rapamycin-Analogon zur Verwendung bei der Behandlung von Erkrankungen
GB201405735D0 (en) * 2014-03-31 2014-05-14 Ge Healthcare As Ultrasound precursor preparation method
GB201411423D0 (en) * 2014-06-26 2014-08-13 Ge Healthcare As Lipid sterilisation method
EP3020813A1 (de) 2014-11-16 2016-05-18 Neurovision Pharma GmbH Antisense-Oligonukleotide als Inhibitoren der TGF-R-Signalgebung
JP2017537907A (ja) 2014-12-22 2017-12-21 ブラッコ・スイス・ソシエテ・アノニムＢｒａｃｃｏ Ｓｕｉｓｓｅ ＳＡ ワクチンとしての使用のためのガス入りの微小胞
WO2017184672A1 (en) * 2016-04-19 2017-10-26 Microvascuar Therapeutics Llc Systems and methods for filling vials with gases
CN111836650B (zh) 2018-03-07 2024-06-18 博莱科瑞士股份有限公司 尺寸可控微泡的制备
EP3990033B1 (de) 2019-06-25 2023-12-06 Bracco Suisse SA Gefriergetrocknete zusammensetzung zur herstellung von kalibrierten gasgefüllten mikrovesikeln
JP7712878B2 (ja) * 2019-06-25 2025-07-24 ブラッコ・スイス・ソシエテ・アノニム 校正されたガス充填微小胞を調製するための凍結乾燥組成物
US10953023B1 (en) * 2020-01-28 2021-03-23 Applaud Medical, Inc. Phospholipid compounds and formulations
CN112891565A (zh) * 2021-04-09 2021-06-04 上海师范大学 锌-二甲基吡啶胺在制备诊断血栓性疾病药物中的应用
EP4105328A1 (de) 2021-06-15 2022-12-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Antisense-oligonukleotide zur prävention von nierenfunktionsstörungen, die durch endotheliale dysfunktion gefördert werden, durch unterdrückung von ephrin-b2
CN117797279B (zh) * 2023-11-07 2025-08-26 浙江普利药业有限公司 一种荧光-磁共振双模态造影剂及其制备方法

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US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
JPH06211645A (ja) * 1993-01-14 1994-08-02 Mitsubishi Kasei Corp リポソーム凍結乾燥製剤

Also Published As

Publication number Publication date
DE69720979T2 (de) 2004-02-26
JP4250747B2 (ja) 2009-04-08
PL328309A1 (en) 1999-01-18
CZ262698A3 (cs) 1999-03-17
DE69720979D1 (de) 2003-05-22
AU722735B2 (en) 2000-08-10
IL125800A0 (en) 1999-04-11
AU1805197A (en) 1997-09-02
KR19990082670A (ko) 1999-11-25
NO983584D0 (no) 1998-08-05
EP0885016B1 (de) 2003-04-16
NO313815B1 (no) 2002-12-09
ATE237362T1 (de) 2003-05-15
CN1213971A (zh) 1999-04-14
HUP9900812A3 (en) 1999-11-29
NO983584L (no) 1998-10-16
WO1997029782A1 (en) 1997-08-21
EP0885016A1 (de) 1998-12-23
NZ331372A (en) 2000-01-28
EA199800739A1 (ru) 1999-02-25
KR100501863B1 (ko) 2005-09-27
CN1092988C (zh) 2002-10-23
HUP9900812A2 (hu) 1999-07-28
JP2000506122A (ja) 2000-05-23
CA2246778A1 (en) 1997-08-21
ES2197331T3 (es) 2004-01-01
EA000900B1 (ru) 2000-06-26

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