EG14354A - Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants - Google Patents

Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants

Info

Publication number: EG14354A
Authority: EG; Egypt
Prior art keywords: useful; inflammatory conditions; preparing novel; relieving inflammatory; aminothiazoles
Prior art date: 1978-06-02

Application number

EG333/79A

Other languages

English (en)

Inventor

George Joseph

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-06-02

Filing date

1979-05-30

Publication date

1984-06-30

1979-05-30 Application filed by Pfizer filed Critical Pfizer

1984-06-30 Application granted granted Critical

1984-06-30 Publication of EG14354A publication Critical patent/EG14354A/xx

Links

RAIPHJJURHTUIC-UHFFFAOYSA-N 1,3-thiazol-2-amine Chemical class NC1=NC=CS1 RAIPHJJURHTUIC-UHFFFAOYSA-N 0.000 title 1
230000004968 inflammatory condition Effects 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16B—DEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
- F16B15/00—Nails; Staples
- F16B15/0023—Nail plates
- F16B2015/0076—Nail plates with provisions for additional fastening means, e.g. hooks, holes for separate screws or nails, adhesive

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

EG333/79A 1978-06-02 1979-05-30 Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants EG14354A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US91183078A	1978-06-02	1978-06-02

Publications (1)

Publication Number	Publication Date
EG14354A true EG14354A (en)	1984-06-30

Family

ID=25430923

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG333/79A EG14354A (en)	1978-06-02	1979-05-30	Process for preparing novel aminothiazoles useful for relieving inflammatory conditions and as immune regulants

Country Status (36)

Country	Link
JP (1)	JPS5936988B2 (de)
AR (1)	AR226285A1 (de)
AT (1)	AT373248B (de)
AU (1)	AU511242B2 (de)
BE (1)	BE876732A (de)
CA (1)	CA1117949A (de)
CH (1)	CH639653A5 (de)
CS (1)	CS216927B2 (de)
DD (1)	DD144055A5 (de)
DE (1)	DE2922523C2 (de)
DK (1)	DK150068C (de)
EG (1)	EG14354A (de)
ES (1)	ES481220A1 (de)
FI (1)	FI68820C (de)
FR (1)	FR2427333A1 (de)
GB (1)	GB2022085B (de)
GR (1)	GR73142B (de)
HK (1)	HK66487A (de)
HU (1)	HU180045B (de)
IE (1)	IE48426B1 (de)
IL (1)	IL57450A (de)
IT (1)	IT1121238B (de)
KE (1)	KE3459A (de)
LU (1)	LU81349A1 (de)
MY (1)	MY8500318A (de)
NL (1)	NL178421C (de)
NO (1)	NO150760C (de)
NZ (1)	NZ190623A (de)
PH (1)	PH17020A (de)
PL (1)	PL117515B1 (de)
PT (1)	PT69718A (de)
SE (1)	SE438333B (de)
SG (1)	SG56184G (de)
SU (1)	SU843746A3 (de)
YU (1)	YU40997B (de)
ZA (1)	ZA792729B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0063575A4 (de) *	1980-10-24	1983-02-14	Ronald Peter Hansen	Staub-ermässigungssystem.
JPS57136579A (en) *	1981-01-21	1982-08-23	Mitsui Toatsu Chem Inc	Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
US4511574A (en) *	1981-01-08	1985-04-16	Mitsui Toatsu Kagaku Kabushiki Kaisha	N-(4-Phenyl-2-thiazolyl)carbamate derivatives
JPS57116067A (en) *	1981-01-12	1982-07-19	Sankyo Kagaku Kk	Novel 8-quinolinesulfonyl derivative, its synthesis and use
US4501750A (en) *	1981-01-13	1985-02-26	Mitsui Toatsu Kaguku Kabushiki Kaisha	Thiazole compounds, a process for preparing same and a pharmaceutical composition containing the thiazole compounds
WO1982002386A1 (en) *	1981-01-13	1982-07-22	Sakano Isao	Aminothiazole derivatives,process for their preparation,and medicinal composition containing same
JPS57154175A (en) *	1981-03-16	1982-09-22	Mitsui Toatsu Chem Inc	2-thiazoleamine derivative, its preparation, and drug composition comprising it
DE3227329A1 (de) *	1982-07-22	1984-01-26	Basf Ag, 6700 Ludwigshafen	Verfahren zur herstellung von 2-n,n-disubstituierten aminothiazolen
WO1986003203A1 (fr) *	1984-11-22	1986-06-05	Yoshitomi Pharmaceutical Industries, Ltd.	Derives de thienylthiazole
FR2581063B1 (fr) *	1985-04-30	1987-07-17	Chauvin Blache Lab	Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique
JPS63152368A (ja) *	1986-06-03	1988-06-24	Sumitomo Pharmaceut Co Ltd	新規なアミノアゾ−ル誘導体およびその酸付加塩
JPH075579B2 (ja) *	1986-09-01	1995-01-25	吉富製薬株式会社	アミノチアゾ−ル化合物
JPH0753666B2 (ja) *	1987-09-14	1995-06-07	久光製薬株式会社	置換ジフェニルチアゾール誘導体からなる抗炎症剤
US5463524A (en) *	1989-08-10	1995-10-31	Commonwealth Scientific And Industrial Research Organisation	Producing electrosuspensions
AU654125B2 (en) *	1991-03-07	1994-10-27	Hisamitsu Pharmaceutical Co., Inc.	Novel diphenylthyazole derivative
FR2692893B1 (fr) *	1992-06-24	1994-09-02	Sanofi Elf	Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
JPH10504542A (ja) *	1994-07-27	1998-05-06	ジー．ディー．サールアンドカンパニー	炎症処置用の置換チアゾール化合物
FR2754258B1 (fr)	1996-10-08	1998-12-31	Sanofi Sa	Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
CA2397661C (en) *	2000-03-01	2012-01-03	Janssen Pharmaceutica N.V.	2,4-disubstituted thiazolyl derivatives
WO2003015777A1 (en) *	2001-08-13	2003-02-27	Lion Bioscience Ag	Nr1h4 nuclear receptor binding compounds
AU2002340010A1 (en) *	2001-09-26	2003-04-07	Bayer Corporation	Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors
MXPA04006709A (es)	2002-01-11	2004-10-04	Sankyo Co	Derivados de aminoalcohol o derivados de acido fosfonico y composiciones farmaceuticas que los contienen.
EP1555264A1 (de) *	2004-01-15	2005-07-20	Sireen AG	Fünfringheterocyclische Verbindungen als Inhibitoren der Familie der SRC Proteinkinasen.
KR20110136901A (ko)	2004-02-24	2011-12-21	상꾜 가부시키가이샤	아미노 알코올 화합물
AU2006244203B2 (en)	2005-05-09	2012-05-03	Achillion Pharmaceuticals, Inc.	Thiazole compounds and methods of use
AU2007207743B2 (en)	2006-01-18	2010-07-08	Amgen Inc.	Thiazole compounds as protein kinase B (PKB) inhibitors
US7919504B2 (en)	2007-07-17	2011-04-05	Amgen Inc.	Thiadiazole modulators of PKB
US7897619B2 (en)	2007-07-17	2011-03-01	Amgen Inc.	Heterocyclic modulators of PKB
WO2012170931A2 (en)	2011-06-10	2012-12-13	Calcimedica, Inc.	Compounds that modulate intracellular calcium
US20130143927A1 (en) *	2011-06-10	2013-06-06	Calcimedica, Inc.	Compounds that modulate intracellular calcium
WO2013059677A1 (en)	2011-10-19	2013-04-25	Calcimedica, Inc.	Compounds that modulate intracellular calcium
CN110590785B (zh) *	2019-09-23	2021-02-02	武汉大学	一种氨基噻唑类化合物及其制备方法与抗肠道病毒71型的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3458526A (en) *	1966-09-26	1969-07-29	Upjohn Co	Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles

1979
- 1979-04-30 DK DK177679A patent/DK150068C/da not_active IP Right Cessation
- 1979-05-23 GB GB7917872A patent/GB2022085B/en not_active Expired
- 1979-05-29 CH CH501679A patent/CH639653A5/fr not_active IP Right Cessation
- 1979-05-30 EG EG333/79A patent/EG14354A/xx active
- 1979-05-30 CS CS793728A patent/CS216927B2/cs unknown
- 1979-05-31 IL IL57450A patent/IL57450A/xx unknown
- 1979-05-31 YU YU1288/79A patent/YU40997B/xx unknown
- 1979-05-31 AU AU47634/79A patent/AU511242B2/en not_active Ceased
- 1979-05-31 HU HU79PI679A patent/HU180045B/hu not_active IP Right Cessation
- 1979-05-31 LU LU81349A patent/LU81349A1/xx unknown
- 1979-05-31 CA CA000328805A patent/CA1117949A/en not_active Expired
- 1979-05-31 SU SU792773929A patent/SU843746A3/ru active
- 1979-05-31 PH PH22588A patent/PH17020A/en unknown
- 1979-05-31 SE SE7904798A patent/SE438333B/sv not_active IP Right Cessation
- 1979-06-01 NL NLAANVRAGE7904337,A patent/NL178421C/xx not_active IP Right Cessation
- 1979-06-01 FI FI791754A patent/FI68820C/fi not_active IP Right Cessation
- 1979-06-01 FR FR7914164A patent/FR2427333A1/fr active Granted
- 1979-06-01 BE BE0/195534A patent/BE876732A/xx not_active IP Right Cessation
- 1979-06-01 DE DE2922523A patent/DE2922523C2/de not_active Expired
- 1979-06-01 IT IT23228/79A patent/IT1121238B/it active
- 1979-06-01 PT PT69718A patent/PT69718A/pt unknown
- 1979-06-01 NO NO791831A patent/NO150760C/no unknown
- 1979-06-01 NZ NZ190623A patent/NZ190623A/en unknown
- 1979-06-01 JP JP54068781A patent/JPS5936988B2/ja not_active Expired
- 1979-06-01 ZA ZA792729A patent/ZA792729B/xx unknown
- 1979-06-01 AR AR276782A patent/AR226285A1/es active
- 1979-06-01 PL PL1979216030A patent/PL117515B1/pl unknown
- 1979-06-01 DD DD79213371A patent/DD144055A5/de not_active IP Right Cessation
- 1979-06-01 GR GR59240A patent/GR73142B/el unknown
- 1979-06-01 ES ES481220A patent/ES481220A1/es not_active Expired
- 1979-06-01 AT AT0401679A patent/AT373248B/de not_active IP Right Cessation
- 1979-08-08 IE IE1069/79A patent/IE48426B1/en unknown
1984
- 1984-08-13 SG SG561/84A patent/SG56184G/en unknown
- 1984-09-24 KE KE3459A patent/KE3459A/xx unknown
1985
- 1985-12-30 MY MY318/85A patent/MY8500318A/xx unknown
1987
- 1987-09-17 HK HK664/87A patent/HK66487A/xx unknown

Also Published As

Publication number	Publication date
NL178421B (nl)	1985-10-16
GB2022085B (en)	1983-01-12
DD144055A5 (de)	1980-09-24
ES481220A1 (es)	1980-09-01
IT1121238B (it)	1986-03-26
NL7904337A (nl)	1979-12-04
FR2427333A1 (fr)	1979-12-28
NO791831L (no)	1979-12-04
FR2427333B1 (de)	1983-05-20
NO150760B (no)	1984-09-03
AU4763479A (en)	1979-12-06
ATA401679A (de)	1983-05-15
LU81349A1 (fr)	1979-12-07
IL57450A (en)	1982-11-30
DK150068B (da)	1986-12-01
HK66487A (en)	1987-09-25
SE7904798L (sv)	1979-12-03
FI791754A7 (fi)	1979-11-26
NZ190623A (en)	1984-07-06
IL57450A0 (en)	1979-09-30
SU843746A3 (ru)	1981-06-30
IT7923228A0 (it)	1979-06-01
DK177679A (da)	1979-12-03
CA1117949A (en)	1982-02-09
FI68820C (fi)	1985-11-11
DE2922523A1 (de)	1979-12-06
JPS5936988B2 (ja)	1984-09-06
CH639653A5 (fr)	1983-11-30
PL117515B1 (en)	1981-08-31
PT69718A (en)	1979-07-01
HU180045B (en)	1983-01-28
YU128879A (en)	1982-10-31
BE876732A (fr)	1979-12-03
PH17020A (en)	1984-05-11
GR73142B (de)	1984-02-09
NL178421C (nl)	1986-03-17
YU40997B (en)	1986-10-31
FI68820B (fi)	1985-07-31
IE791069L (en)	1979-12-02
CS216927B2 (en)	1982-12-31
GB2022085A (en)	1979-12-12
DK150068C (da)	1987-06-29
AT373248B (de)	1983-12-27
SG56184G (en)	1985-03-08
NO150760C (no)	1984-12-12
IE48426B1 (en)	1985-01-23
KE3459A (en)	1984-10-12
AU511242B2 (en)	1980-08-07
MY8500318A (en)	1985-12-31
SE438333B (sv)	1985-04-15
PL216030A1 (de)	1980-03-10
AR226285A1 (es)	1982-06-30
DE2922523C2 (de)	1982-10-21
ZA792729B (en)	1981-03-25
JPS54160369A (en)	1979-12-19

Publication	Publication Date	Title
PT69718A (en)	1979-07-01	Process for preparing novel aminothiazoles
GB2017682B (en)	1982-08-25	Process for the preparation of aliphatic amines
DE2966723D1 (en)	1984-04-05	Process for the preparation of 6-amino-6-desoxy-l-sorbose
DE2960539D1 (en)	1981-10-29	Process for the preparation of 4-fluor-3-phenoxytoluene
DE2962201D1 (en)	1982-03-25	Process for the preparation of amines
DE2962321D1 (en)	1982-04-29	Process for the preparation of shaped articles
DE2963068D1 (en)	1982-07-29	Process for the preparation of benzothiazole-disulphide
DE2961140D1 (en)	1981-12-10	Process for the preparation of azaspirodecanes
DE2961237D1 (en)	1982-01-14	Process for the preparation of hydroxyalkyl-perfluoralkane-sulfonamides
ZA791589B (en)	1980-04-30	Process for the preparation of 2-mercaptobenzthiazole
DE2960104D1 (en)	1981-02-26	Process for the preparation of thiazole derivatives
DE2960278D1 (en)	1981-07-30	Process for the preparation of 4-acyloxy-2-methylcrotonaldehydes
KE3399A (en)	1984-06-08	Process for the preparation of 1-n-acyl-aminoglycosides
GB2015998B (en)	1982-07-14	Process for the preparation of p-amino-diphenylamine
DE2960541D1 (en)	1981-10-29	Process for the preparation of 3-phenoxybenzaldehydes
GB2016478B (en)	1982-06-30	Process for the preparation of ceruletide
DE2961447D1 (en)	1982-01-28	Process for the preparation of p-nitroso-diphenylhydroxylamines
GB2088852B (en)	1982-11-24	Process for the preparation of 9-oxobenzomorphans
DE2860555D1 (en)	1981-04-16	Process for the preparation of 4-methyl-5-chloromethyl-imidazole
DE2961888D1 (en)	1982-03-04	Process for the preparation of 6-hydroxypyrid-2-ones
GB2018774B (en)	1982-12-01	Process for the preparation of 2-mercaptobenzthiazole
DE2960495D1 (en)	1981-10-22	Process for the preparation of benzothiazolesulfenamides
EP0044091A3 (en)	1982-03-31	Process for the preparation of n-alkylamino-benzophenones
DE2961832D1 (en)	1982-02-25	Process for the preparation of hydro-diphenyl amines
DE2960822D1 (en)	1981-12-03	Process for the preparation of aminodioxyanthracenes