EG20082A - Process for preparing of octadecyl-(2-N-methylpiperidino)-ethyl-phosphate - Google Patents

Process for preparing of octadecyl-(2-N-methylpiperidino)-ethyl-phosphate

Info

Publication number: EG20082A
Authority: EG; Egypt
Prior art keywords: methylpiperidino; octadecyl; phosphate; ethyl; preparing
Prior art date: 1991-07-04

Application number

EG34592A

Other languages

English (en)

Original Assignee

Asta Medica Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-04

Filing date

1992-07-01

Publication date

1997-05-31

1992-07-01 Application filed by Asta Medica Ag filed Critical Asta Medica Ag

1997-05-31 Application granted granted Critical

1997-05-31 Publication of EG20082A publication Critical patent/EG20082A/xx

Links

238000004519 manufacturing process Methods 0.000 title 1
230000000118 anti-neoplastic effect Effects 0.000 abstract 1
ZJXZSIYSNXKHEA-UHFFFAOYSA-N ethyl dihydrogen phosphate Chemical compound CCOP(O)(O)=O ZJXZSIYSNXKHEA-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicinal Preparation (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

EG34592A 1991-07-04 1992-07-01 Process for preparing of octadecyl-(2-N-methylpiperidino)-ethyl-phosphate EG20082A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4122140		1991-07-04
DE4129364		1991-09-04

Publications (1)

Publication Number	Publication Date
EG20082A true EG20082A (en)	1997-05-31

Family

ID=25905206

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG34592A EG20082A (en)	1991-07-04	1992-07-01	Process for preparing of octadecyl-(2-N-methylpiperidino)-ethyl-phosphate

Country Status (19)

Country	Link
US (1)	US5219866A (fr)
EP (1)	EP0521353B1 (fr)
JP (1)	JP3176720B2 (fr)
KR (1)	KR100255436B1 (fr)
CN (1)	CN1030658C (fr)
AT (1)	ATE136783T1 (fr)
AU (1)	AU651224B2 (fr)
CA (1)	CA2073146C (fr)
DE (2)	DE4219972A1 (fr)
DK (1)	DK0521353T3 (fr)
EG (1)	EG20082A (fr)
ES (1)	ES2086026T3 (fr)
FI (1)	FI108035B (fr)
GR (1)	GR3019776T3 (fr)
HU (2)	HUT61561A (fr)
IE (1)	IE73200B1 (fr)
IL (1)	IL102380A (fr)
NO (1)	NO303939B1 (fr)
PL (3)	PL173794B1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8383605B2 (en) *	2002-07-30	2013-02-26	Aeterna Zentaris Gmbh	Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals
JP2005535688A (ja)	2002-07-30	2005-11-24	ツェンタリスゲゼルシャフトミットベシュレンクテルハフツング	抗腫瘍医薬との組合せにおけるアルキルホスホコリンの使用
UA99434C2 (ru) *	2005-12-19	2012-08-27	Аетерна Центаріс Гмбх	Применение производных алкилфосфолипидов со сниженной цитотоксичностью
EP1962862B1 (fr) *	2005-12-19	2013-09-04	Æterna Zentaris GmbH	Nouveaux alkylphospholipides et leur utilisation
JP5068630B2 (ja) *	2007-11-15	2012-11-07	オルガノ株式会社	アルコール含有溶液中のアルデヒド化合物の除去方法及び該方法により精製された醸造酒
WO2011123691A1 (fr)	2010-03-31	2011-10-06	Keryx Biopharmaceuticals, Inc.	Périfosine et capécitabine en tant que traitement combiné du cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU301951A1 (ru) *	1970-06-01	1973-04-05	В. А. Чернов, Т. С. Сафонова, Н. В. Сазонов, А. А. Кропачева,	Лекарственное средство
JPS5984824A (ja) *	1982-11-08	1984-05-16	Takeda Chem Ind Ltd	抗腫瘍剤
ATE158295T1 (de) *	1991-07-04	1997-10-15	Asta Medica Ag	Verfahren zur herstellung von alkylphosphocholinen und reinherstellung derselben

1992
- 1992-06-19 AT AT92110347T patent/ATE136783T1/de not_active IP Right Cessation
- 1992-06-19 DE DE4219972A patent/DE4219972A1/de not_active Withdrawn
- 1992-06-19 DE DE59205998T patent/DE59205998D1/de not_active Expired - Fee Related
- 1992-06-19 ES ES92110347T patent/ES2086026T3/es not_active Expired - Lifetime
- 1992-06-19 EP EP92110347A patent/EP0521353B1/fr not_active Expired - Lifetime
- 1992-06-19 DK DK92110347.9T patent/DK0521353T3/da active
- 1992-07-01 US US07/907,025 patent/US5219866A/en not_active Expired - Lifetime
- 1992-07-01 EG EG34592A patent/EG20082A/xx active
- 1992-07-02 PL PL92311787A patent/PL173794B1/pl not_active IP Right Cessation
- 1992-07-02 IL IL10238092A patent/IL102380A/en not_active IP Right Cessation
- 1992-07-02 PL PL92295128A patent/PL173905B1/pl not_active IP Right Cessation
- 1992-07-02 PL PL92311788A patent/PL173869B1/pl not_active IP Right Cessation
- 1992-07-03 IE IE922183A patent/IE73200B1/en not_active IP Right Cessation
- 1992-07-03 KR KR1019920011821A patent/KR100255436B1/ko not_active Expired - Fee Related
- 1992-07-03 AU AU19435/92A patent/AU651224B2/en not_active Ceased
- 1992-07-03 JP JP17691592A patent/JP3176720B2/ja not_active Expired - Fee Related
- 1992-07-03 CA CA002073146A patent/CA2073146C/fr not_active Expired - Fee Related
- 1992-07-03 FI FI923088A patent/FI108035B/fi active
- 1992-07-03 CN CN92105452A patent/CN1030658C/zh not_active Expired - Fee Related
- 1992-07-03 HU HU9202232A patent/HUT61561A/hu unknown
- 1992-07-03 NO NO922642A patent/NO303939B1/no unknown
1995
- 1995-06-16 HU HU95P/P00233P patent/HU211483A9/hu unknown
1996
- 1996-04-29 GR GR960401156T patent/GR3019776T3/el unknown

Also Published As

Publication number	Publication date
IL102380A (en)	1996-10-16
KR100255436B1 (ko)	2000-05-01
HUT61561A (en)	1993-01-28
US5219866A (en)	1993-06-15
KR930001909A (ko)	1993-02-22
NO922642L (no)	1993-01-05
PL173794B1 (pl)	1998-05-29
GR3019776T3 (en)	1996-07-31
FI108035B (fi)	2001-11-15
CN1030658C (zh)	1996-01-10
IL102380A0 (en)	1993-01-14
DE4219972A1 (de)	1993-01-07
EP0521353A1 (fr)	1993-01-07
HU9202232D0 (en)	1992-10-28
PL295128A1 (en)	1993-08-23
HU211483A9 (en)	1995-11-28
IE73200B1 (en)	1997-05-07
ES2086026T3 (es)	1996-06-16
DE59205998D1 (de)	1996-05-23
EP0521353B1 (fr)	1996-04-17
JPH05213980A (ja)	1993-08-24
FI923088A0 (fi)	1992-07-03
JP3176720B2 (ja)	2001-06-18
NO303939B1 (no)	1998-09-28
FI923088L (fi)	1993-01-05
PL173905B1 (pl)	1998-05-29
IE922183A1 (en)	1993-01-13
CA2073146A1 (fr)	1993-01-05
AU651224B2 (en)	1994-07-14
DK0521353T3 (da)	1996-05-13
CN1068119A (zh)	1993-01-20
ATE136783T1 (de)	1996-05-15
PL173869B1 (pl)	1998-05-29
AU1943592A (en)	1993-03-11
CA2073146C (fr)	2002-05-28
NO922642D0 (no)	1992-07-03

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