EG20085A - Process for preparing of imidazopyridine PAF/H2 antagonists - Google Patents

Process for preparing of imidazopyridine PAF/H2 antagonists

Info

Publication number: EG20085A
Authority: EG; Egypt
Prior art keywords: pct; paf; antagonists; sec; imidazopyridine
Prior art date: 1991-02-13

Application number

EG8792A

Other languages

English (en)

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-02-13

Filing date

1992-02-10

Publication date

1997-05-31

1992-02-10 Application filed by Pfizer filed Critical Pfizer

1997-05-31 Application granted granted Critical

1997-05-31 Publication of EG20085A publication Critical patent/EG20085A/xx

Links

GAMYYCRTACQSBR-UHFFFAOYSA-N 4-azabenzimidazole Chemical compound C1=CC=C2NC=NC2=N1 GAMYYCRTACQSBR-UHFFFAOYSA-N 0.000 title 1
229940122957 Histamine H2 receptor antagonist Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
206010039085 Rhinitis allergic Diseases 0.000 abstract 1
230000000172 allergic effect Effects 0.000 abstract 1
201000010105 allergic rhinitis Diseases 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
208000010668 atopic eczema Diseases 0.000 abstract 1
125000005605 benzo group Chemical group 0.000 abstract 1
125000006355 carbonyl methylene group Chemical group [H]C([H])([*:2])C([*:1])=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
229960001340 histamine Drugs 0.000 abstract 1
230000004968 inflammatory condition Effects 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Immunology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Cosmetics (AREA)
Prostheses (AREA)
Steroid Compounds (AREA)

EG8792A 1991-02-13 1992-02-10 Process for preparing of imidazopyridine PAF/H2 antagonists EG20085A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB919102997A GB9102997D0 (en)	1991-02-13	1991-02-13	Therapeutic agents

Publications (1)

Publication Number	Publication Date
EG20085A true EG20085A (en)	1997-05-31

Family

ID=10689943

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG8792A EG20085A (en)	1991-02-13	1992-02-10	Process for preparing of imidazopyridine PAF/H2 antagonists

Country Status (29)

Country	Link
US (1)	US5358953A (de)
EP (1)	EP0572425B1 (de)
JP (1)	JP2506541B2 (de)
KR (1)	KR970005302B1 (de)
CN (1)	CN1040326C (de)
AT (1)	ATE109482T1 (de)
AU (1)	AU650322B2 (de)
BR (1)	BR9205615A (de)
CA (1)	CA2099381C (de)
CZ (1)	CZ280504B6 (de)
DE (1)	DE69200304T2 (de)
DK (1)	DK0572425T3 (de)
EG (1)	EG20085A (de)
ES (1)	ES2059212T3 (de)
FI (1)	FI933531A7 (de)
GB (1)	GB9102997D0 (de)
HU (2)	HUT65947A (de)
IE (1)	IE65125B1 (de)
IL (1)	IL100887A (de)
MX (1)	MX9200589A (de)
MY (1)	MY108437A (de)
NO (1)	NO300592B1 (de)
NZ (1)	NZ241597A (de)
PL (1)	PL169304B1 (de)
RU (1)	RU2114845C1 (de)
TW (1)	TW227000B (de)
WO (1)	WO1992014734A1 (de)
YU (1)	YU48238B (de)
ZA (1)	ZA921005B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2042421B1 (es) *	1992-05-22	1994-08-01	Uriach & Cia Sa J	Procedimiento para la obtencion de la 8-cloro-11-1-(5-metil-3-piridil)metil-4-piperidiliden-6,11-dihidro-5h-benzo5,6ciclohepta1,2-bpiridina.
US5753671A (en) *	1994-08-10	1998-05-19	British Biotech Pharmaceuticals Limited	Imidazopyridine derivatives as dual histamine (H1) and platelet activating factor (PAF) antagonists
ES2087038B1 (es) *	1994-11-07	1997-03-16	Uriach & Cia Sa J	Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) *	1995-04-19	1996-10-22	Abbott Laboratories	Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) *	1995-04-28	1995-06-14	British Biotech Pharm	Benzimidazole derivatives
AU698487B2 (en) *	1995-08-05	1998-10-29	British Biotech Pharmaceuticals Limited	Imidazopyridine derivatives
SE9801526D0 (sv) *	1998-04-29	1998-04-29	Astra Ab	New compounds
CA2774959C (en)	2000-08-04	2016-05-31	Dmi Biosciences, Inc.	Method of using diketopiperazines and composition containing them
CN103191409A (zh)	2003-05-15	2013-07-10	Dmi生物科学公司	T-细胞介导的疾病的治疗
US7687515B2 (en) *	2006-01-17	2010-03-30	N.V. Organon	6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
AU2008349239B2 (en)	2008-01-30	2012-12-06	Nippon Zoki Pharmaceutical Co., Ltd.	Piperidine derivative
US8217047B2 (en)	2008-05-27	2012-07-10	Dmi Acquisition Corp.	Therapeutic methods and compounds
EP2727919B1 (de) *	2011-06-28	2019-05-08	Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd.	Benzocycloheptanthiophenderivate für antiallergische reaktionen
EP2765968A4 (de)	2011-10-10	2015-01-21	Ampio Pharmaceuticals Inc	Implantierbare medizinprodukte mit erhöhter immuntoleranz sowie verfahren zur herstellung und implantation
CA2846598C (en)	2011-10-10	2019-12-10	Ampio Pharmaceuticals, Inc.	Treatment of degenerative joint disease
HK1198812A1 (en) *	2011-10-28	2015-06-12	Ampio Pharmaceuticals, Inc.	Treatment of rhinitis
EA201500943A1 (ru)	2013-03-15	2016-08-31	Ампио Фармасьютикалс, Инк.	Составы для мобилизации, хоуминга, размножения и дифференцировки стволовых клеток и способы применения составов
CA2958080A1 (en)	2014-08-18	2016-02-25	Ampio Pharmaceuticals, Inc.	Treatment of joint conditions
US11389512B2 (en)	2015-06-22	2022-07-19	Ampio Pharmaceuticals, Inc.	Use of low molecular weight fractions of human serum albumin in treating diseases
CN113880801A (zh) *	2020-07-03	2022-01-04	合肥医工医药股份有限公司	一类三环化合物、其制备方法及其医药用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL132137C (de) *	1963-04-24
EP0404797B1 (de) *	1988-03-15	1995-02-01	G.D. Searle & Co.	1H/3H-[4-(N,N-CYCLOALKYL UND/ODER VERZWEIGTES ALKYLCARBOXAMIDO)-BENZYL]IMDAZO[4,5-c]PYRIDINE ALS PAF-ANTAGONISTEN
NZ228889A (en) *	1988-04-28	1991-09-25	Schering Corp	Fused tri- or tetracyclic heterocyclic compounds and pharmaceutical compositions
US5250681A (en) *	1988-06-02	1993-10-05	Ajinomoto Co., Inc.	Piperidine derivatives and hypotensives containing the same
US5114919A (en) *	1990-02-26	1992-05-19	Merck & Co., Inc.	Adjuncts in cancer chemotherapy
BR9106433A (pt) *	1990-05-09	1993-05-04	Pfizer	Imidazo (4,5-c) piridinas com atividade antagonista ao paf

1991
- 1991-02-13 GB GB919102997A patent/GB9102997D0/en active Pending
1992
- 1992-01-24 PL PL92300296A patent/PL169304B1/pl unknown
- 1992-01-24 EP EP92902889A patent/EP0572425B1/de not_active Expired - Lifetime
- 1992-01-24 CA CA002099381A patent/CA2099381C/en not_active Expired - Fee Related
- 1992-01-24 DE DE69200304T patent/DE69200304T2/de not_active Expired - Fee Related
- 1992-01-24 DK DK92902889.2T patent/DK0572425T3/da active
- 1992-01-24 AT AT92902889T patent/ATE109482T1/de not_active IP Right Cessation
- 1992-01-24 RU RU93054165A patent/RU2114845C1/ru active
- 1992-01-24 BR BR9205615A patent/BR9205615A/pt not_active Application Discontinuation
- 1992-01-24 AU AU11683/92A patent/AU650322B2/en not_active Ceased
- 1992-01-24 HU HU9302327A patent/HUT65947A/hu unknown
- 1992-01-24 WO PCT/EP1992/000163 patent/WO1992014734A1/en not_active Ceased
- 1992-01-24 US US08/087,736 patent/US5358953A/en not_active Expired - Fee Related
- 1992-01-24 JP JP4503504A patent/JP2506541B2/ja not_active Expired - Fee Related
- 1992-01-24 ES ES92902889T patent/ES2059212T3/es not_active Expired - Lifetime
- 1992-01-24 FI FI933531A patent/FI933531A7/fi not_active Application Discontinuation
- 1992-01-24 KR KR1019930702352A patent/KR970005302B1/ko not_active Expired - Fee Related
- 1992-02-06 IL IL10088792A patent/IL100887A/en not_active IP Right Cessation
- 1992-02-10 EG EG8792A patent/EG20085A/xx active
- 1992-02-10 TW TW081100891A patent/TW227000B/zh active
- 1992-02-11 MX MX9200589A patent/MX9200589A/es unknown
- 1992-02-12 IE IE920449A patent/IE65125B1/en not_active IP Right Cessation
- 1992-02-12 ZA ZA921005A patent/ZA921005B/xx unknown
- 1992-02-12 NZ NZ241597A patent/NZ241597A/en unknown
- 1992-02-12 YU YU14392A patent/YU48238B/sh unknown
- 1992-02-12 CZ CS92425A patent/CZ280504B6/cs not_active IP Right Cessation
- 1992-02-12 MY MYPI92000223A patent/MY108437A/en unknown
- 1992-02-13 CN CN92100974A patent/CN1040326C/zh not_active Expired - Fee Related
1993
- 1993-08-13 NO NO932889A patent/NO300592B1/no unknown
1995
- 1995-06-09 HU HU95P/P00175P patent/HU211202A9/hu unknown

Also Published As

Publication number	Publication date
ZA921005B (en)	1993-08-12
ATE109482T1 (de)	1994-08-15
TW227000B (de)	1994-07-21
FI933531L (fi)	1993-08-10
HU211202A9 (en)	1995-11-28
DE69200304T2 (de)	1994-12-08
CN1064275A (zh)	1992-09-09
AU650322B2 (en)	1994-06-16
NO932889L (no)	1993-08-13
AU1168392A (en)	1992-09-15
YU14392A (sh)	1994-11-15
CS42592A3 (en)	1992-09-16
FI933531A0 (fi)	1993-08-10
DK0572425T3 (da)	1994-09-12
HUT65947A (en)	1994-08-29
YU48238B (sh)	1997-08-22
HU9302327D0 (en)	1993-10-28
FI933531A7 (fi)	1993-08-10
JP2506541B2 (ja)	1996-06-12
EP0572425A1 (de)	1993-12-08
WO1992014734A1 (en)	1992-09-03
GB9102997D0 (en)	1991-03-27
IE920449A1 (en)	1992-08-12
NO300592B1 (no)	1997-06-23
NO932889D0 (no)	1993-08-13
NZ241597A (en)	1993-04-28
CN1040326C (zh)	1998-10-21
BR9205615A (pt)	1994-05-17
EP0572425B1 (de)	1994-08-03
IL100887A0 (en)	1992-11-15
CA2099381C (en)	1996-07-09
CA2099381A1 (en)	1992-08-14
RU2114845C1 (ru)	1998-07-10
PL169304B1 (pl)	1996-06-28
DE69200304D1 (de)	1994-09-08
IL100887A (en)	1996-01-19
MY108437A (en)	1996-09-30
US5358953A (en)	1994-10-25
JPH06504992A (ja)	1994-06-09
KR970005302B1 (ko)	1997-04-15
MX9200589A (es)	1992-10-01
CZ280504B6 (cs)	1996-02-14
IE65125B1 (en)	1995-10-04
ES2059212T3 (es)	1994-11-01

Publication	Publication Date	Title
EG20085A (en)	1997-05-31	Process for preparing of imidazopyridine PAF/H2 antagonists
YU48426B (sh)	1998-07-10	Novi supstituisani pirazolilpirazoli, postupak njihovog dobijanja, medjuproizvodi za njihovo dobijanje i primena kao sredstava sa herbicidnim delovanjem
MXPA02011417A (es)	2003-04-25	1-aminoalquil-lactamas sustituidas y su uso como antagonistas de receptores muscarinicos.
ES2162061T3 (es)	2001-12-16	Derivados de piperidina como antagonistas de la neuroquinina.
YU84791A (sh)	1994-06-10	Biciklicni 1-aza-cikloalkalni
PT75471A (fr)	1982-09-01	Procede de preparation d'ethers tricycliques
DE69530094D1 (de)	2003-04-30	Thiazolidindione derivate, ihre herstellung und verwendung
RU93054165A (ru)	1996-09-10	Производные имидазопиридина, способ их получения, фармацевтическая композиция, способ лечения
FI922341A0 (fi)	1992-05-22	Piperidin- och pyrrolidinderivat.
SG164268A1 (en)	2010-09-29	Quinolin-4-yl derivatives i
EP0335979A4 (en)	1992-02-26	Thienopyrimidine derivatives
DE3855902D1 (de)	1997-06-12	Herstellungsverfahren für 2,5-Diamino-6-nitro-pyridinderivate sowie neue 2,5-Diamino-6-nitro-pyridinderivate
PT1018512E (pt)	2004-08-31	Novos derivados basicos de benzo¬e\|isoindol-1-onas e pirrolo¬3,4-c\|quinolin-1-onas com actividade antagonista de 5ht3 a sua preparacao e o seu uso terapeutico
YU4393A (sr)	1996-01-09	Supstituisani heksahidroazepinoni i tetrahidrobenzazepinoni
SE8801964D0 (sv)	1988-05-26	New 5-(omega-ammonio acyloxy methylene) tetrahydrofurans and tetrahydrothiophenes
TW225989B (de)	1994-07-01
MX9606654A (es)	1997-12-31	Derivados de alaquildiamina substituida y su uso como antagonistas de taquicinina.
GR75618B (de)	1984-08-01
AU564799B2 (en)	1987-08-27	Composition for prophylactic and preventative of ketosis in livestock
HU900728D0 (en)	1990-04-28	Process for preparation of calcium antagonistics
PT100223A (pt)	1993-09-30	Processo para a preparacao de imidazopiridinas antagonistas de paf/h1
DE69006366D1 (de)	1994-03-10	BENZO[b]PHENANTHROLINDERIVATE, IHRE HERSTELLUNG UND IHRE THERAPEUTISCHE VERWENDUNG.
FI973558L (fi)	1997-08-29	Menetelmä terapeuttisesti käytt¦kelpoisten 2-metyyli-imidatsoÄ4,5-cÜpyrid-1-yylijohdannaisten valmistamiseksi
GR70255B (de)	1982-09-02
HUT44502A (en)	1988-03-28	Process for producing 3-amino-dihydropyridine derivatives and pharmaceutical compositions containing them