EG20569A - Novel (1-heteroazolyl -1- heterocyclyl ) alkane derivatives and their use as neuroprotective agents - Google Patents

Novel (1-heteroazolyl -1- heterocyclyl ) alkane derivatives and their use as neuroprotective agents

Info

Publication number
EG20569A
EG20569A EG40594A EG40594A EG20569A EG 20569 A EG20569 A EG 20569A EG 40594 A EG40594 A EG 40594A EG 40594 A EG40594 A EG 40594A EG 20569 A EG20569 A EG 20569A
Authority
EG
Egypt
Prior art keywords
heteroazolyl
heterocyclyl
novel
neuroprotective agents
alkane derivatives
Prior art date
Application number
EG40594A
Other languages
English (en)
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Application granted granted Critical
Publication of EG20569A publication Critical patent/EG20569A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EG40594A 1993-07-06 1994-07-06 Novel (1-heteroazolyl -1- heterocyclyl ) alkane derivatives and their use as neuroprotective agents EG20569A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE19939302332A SE9302332D0 (sv) 1993-07-06 1993-07-06 New compounds

Publications (1)

Publication Number Publication Date
EG20569A true EG20569A (en) 1999-08-30

Family

ID=20390539

Family Applications (1)

Application Number Title Priority Date Filing Date
EG40594A EG20569A (en) 1993-07-06 1994-07-06 Novel (1-heteroazolyl -1- heterocyclyl ) alkane derivatives and their use as neuroprotective agents

Country Status (24)

Country Link
US (2) US5731335A (cs)
EP (1) EP0707584A1 (cs)
JP (1) JPH08512312A (cs)
CN (1) CN1126994A (cs)
AU (1) AU691506B2 (cs)
BR (1) BR9406923A (cs)
CA (1) CA2164856A1 (cs)
CZ (1) CZ5396A3 (cs)
EE (1) EE03193B1 (cs)
EG (1) EG20569A (cs)
FI (1) FI960076L (cs)
HU (1) HUT75097A (cs)
IL (1) IL110157A (cs)
IS (1) IS4182A (cs)
MX (1) MX9405110A (cs)
NO (1) NO305955B1 (cs)
NZ (1) NZ268689A (cs)
PL (1) PL176471B1 (cs)
RU (1) RU2124011C1 (cs)
SE (1) SE9302332D0 (cs)
SG (1) SG64891A1 (cs)
SK (1) SK159895A3 (cs)
WO (1) WO1995001979A1 (cs)
ZA (1) ZA944569B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9604242D0 (en) 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
DE19645313A1 (de) 1996-11-04 1998-05-07 Basf Ag Substituierte 3-Benzylpyrazole
ES2259459T3 (es) * 1997-11-19 2006-10-01 Takeda Pharmaceutical Company Limited Nuevos inhibidores de apoptosis.
GB9726569D0 (en) * 1997-12-16 1998-02-11 Univ Southampton Neuroprotective agents
AR035016A1 (es) 1999-08-25 2004-04-14 Takeda Chemical Industries Ltd Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima.
EP1292577B1 (en) 2000-03-24 2012-10-24 Euro-Celtique S.A. Aryl substituted pyrazoles, triazoles and tetrazoles as sodium channel blocker
RS50521B (sr) 2004-01-12 2010-05-07 Applied Research Systems Ars Holding N.V. Derivati tiazola i njihova upotreba
WO2006031631A1 (en) * 2004-09-10 2006-03-23 Syngenta Limited Substituted isoxazoles as fungicides
US7888376B2 (en) * 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
RU2472788C9 (ru) * 2007-05-23 2013-04-20 Аллерган, Инк. (бициклогетероарил)имидазолил)метилгетероарильные соединения как агонисты адренергических рецепторов
WO2009123164A1 (ja) * 2008-04-02 2009-10-08 塩野義製薬株式会社 血管内皮リパーゼ阻害活性を有するヘテロ環誘導体
CN103003268A (zh) * 2010-07-19 2013-03-27 先正达参股股份有限公司 作为杀微生物剂的异噁唑、异噻唑、呋喃以及噻吩化合物
EP2447261A1 (en) * 2010-10-29 2012-05-02 Basf Se Pyrrole, furane and thiophene derivatives and their use as fungicides
US9150527B2 (en) * 2011-08-30 2015-10-06 Innocrin Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4367090A (en) * 1981-07-17 1983-01-04 Rhone-Poulenc Agrochimie Herbicidal N-(5,5-dimethyloxazolideneyl-2,4-dione) 5-(substituted phenoxy-2-substituted benzamides
JPS58148882A (ja) * 1982-02-26 1983-09-05 Tanabe Seiyaku Co Ltd フリルオキサゾリル酢酸誘導体及びその製法
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な１，２，４−オキサジアゾ−ル誘導体
JPH01249760A (ja) * 1988-03-29 1989-10-05 Yamaha Corp ホトクロミック化合物
SU1657505A1 (ru) * 1989-07-17 1991-06-23 Казанский научно-исследовательский технологический и проектный институт химико-фотографической промышленности Производственного объединения "Тасма" Производные 1-(морфолинокарбонил)-или 1-(морфолинокарбонилокси)-пиридиний хлорида в качестве дубителей дл желатинсодержащих слоев галогенсеребр ных фотографических материалов
US5086064A (en) * 1990-03-27 1992-02-04 Warner-Lambert Company 3,5-di-tertiary-butyl-4-hydroxyphenyl thiazolyl, oxazolyl, and imidazolyl methanones and related compounds as antiinflammatory agents
US5068237A (en) * 1990-05-21 1991-11-26 Warner-Lambert Company Substituted furans and derivatives thereof acting at muscarinic receptors
CA2126976A1 (en) * 1991-12-31 1993-07-08 Hisashi Takasugi Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity

Also Published As

Publication number Publication date
ZA944569B (en) 1995-02-15
NO305955B1 (no) 1999-08-23
BR9406923A (pt) 1996-07-30
SG64891A1 (en) 1999-05-25
NZ268689A (en) 1997-11-24
EE03193B1 (et) 1999-06-15
EP0707584A1 (en) 1996-04-24
AU7197794A (en) 1995-02-06
PL312417A1 (en) 1996-04-15
FI960076A7 (fi) 1996-01-08
HU9503744D0 (en) 1996-02-28
IL110157A (en) 2000-01-31
MX9405110A (es) 1995-01-31
CZ5396A3 (en) 1996-06-12
SK159895A3 (en) 1996-09-04
HUT75097A (en) 1997-04-28
IL110157A0 (en) 1994-10-07
US5607956A (en) 1997-03-04
PL176471B1 (pl) 1999-06-30
JPH08512312A (ja) 1996-12-24
CN1126994A (zh) 1996-07-17
US5731335A (en) 1998-03-24
RU2124011C1 (ru) 1998-12-27
AU691506B2 (en) 1998-05-21
CA2164856A1 (en) 1995-01-19
WO1995001979A1 (en) 1995-01-19
FI960076A0 (fi) 1996-01-08
FI960076L (fi) 1996-01-08
NO960028L (no) 1996-02-27
NO960028D0 (no) 1996-01-04
IS4182A (is) 1995-01-07
SE9302332D0 (sv) 1993-07-06

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